• 7062 Citations
1992 …2020

Research output per year

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Personal profile

Research interests

Our laboratory is focused on the immunologic intervention to cancer via vaccine development. We are also characterizing the biology of the cell adhesion molecule, EpCAM. EpCAM is overexpressed in breast cancer and this overexpression correlates with poor prognosis. We are interested in the molecular controls that regulate EpCAM expression in breast cancer. Our studies have also identified the role EpCAM has in breast cancer invasion and we are further characterizing the biological signaling of EpCAM in human breast cancer.

Areas of Clinical Interest

Endocrine surgery, including thyroid and parathyroid surgery; minimally invasive parathyroid surgery; breast surgery, including breast cancer surgery

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Research Output

cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity

Ferris, S. T., Durai, V., Wu, R., Theisen, D. J., Ward, J. P., Bern, M. D., Davidson, J. T., Bagadia, P., Liu, T., Briseño, C. G., Li, L., Gillanders, W., Wu, G. F., Yokoyama, W. M., Murphy, T. L., Schreiber, R. D. & Murphy, K. M., Aug 27 2020, In : Nature. 584, 7822, p. 624-629 6 p.

Research output: Contribution to journalArticle

  • PVACtools: A computational toolkit to identify and visualize cancer neoantigens

    Hundal, J., Kiwala, S., McMichael, J., Miller, C. A., Xia, H., Wollam, A. T., Liu, C. J., Zhao, S., Feng, Y. Y., Graubert, A. P., Wollam, A. Z., Neichin, J., Neveau, M., Walker, J., Gillanders, W. E., Mardis, E. R., Griffith, O. L. & Griffith, M., Mar 1 2020, In : Cancer immunology research. 8, 3, p. 409-420 12 p.

    Research output: Contribution to journalArticle

    Open Access
  • 3 Scopus citations

    The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution

    Human Tumor Atlas Network, Apr 16 2020, In : Cell. 181, 2, p. 236-249 14 p.

    Research output: Contribution to journalReview article

    Open Access
  • 3 Scopus citations

    Best practices for bioinformatic characterization of neoantigens for clinical utility

    Richters, M. M., Xia, H., Campbell, K. M., Gillanders, W. E., Griffith, O. L. & Griffith, M., Aug 28 2019, In : Genome medicine. 11, 1, 56.

    Research output: Contribution to journalReview article

    Open Access
  • 14 Scopus citations