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Weikai Li

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Weikai Li

Roy and Diana Vagelos Professor of Biochemistry and Molecular Biophysics, Professor of Biochemistry and Molecular Biophysics

 https://orcid.org/0000-0002-8711-1904

    Willing to Mentor

    Available to Mentor:

    PhD Students, Post-Baccalaureate Students, Postdocs

    • 1944
      Citations
    1997 …2025

    Research activity per year

    Personal profile

    Research interests

    Dr. Weikai Li’s lab studies membrane enzymes, transporters and adhesion molecules that are important therapeutic targets in hematology and cardiovascular biology. To support the study, the lab has developed unique multidisciplinary approaches that combine novel structural biology and mass spectrometry methods with biochemistry and cell biology. Recent publications of the lab include those in Science, Science Adv., EMBO J and NSMB. The lab is well funded by five grants from NIH and other foundations,. More information of the lab can be found at https://weikailab.wustl.edu.

    Mentoring

    The lab culture encourages free exploration, and trainees are welcome to develop their own research projects and strategies that are of mutual interest. High degrees of motivation and independency are greatly appreciated. On the other hand, the PI is always available for advices or open discussions.
     
    Based on previous experiences and research interests, trainees may choose to work on cryo-EM and crystal structures of membrane proteins, study their biochemistry and cell biology, or combine with mass spectrometry to elucidate their native states and interactions."
     
    Trainees are supported in every aspect for their growth and future career. To expand their current knowledge, the lab is well established in the structural biology, biochemistry, and cell biology studies of membrane proteins, and has developed novel methods for these studies, such as live cell footprinting (NSMB 2007) and fast structure determination (Sci. Adv. 2020). Moreover, we have strong collaborators ranging from mouse and stem cell studies, mass spectrometry, to immunology and virology. Trainees are encouraged to join regular joint meetings with these collaborators. The PI provides very strong support when trainees are ready for their future academic or industrial career."

    Available to Mentor:

    • Post-Baccalaureate Students
    • PhD Students
    • Postdocs

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