Wayne Yokoyama

Research Output

Research Output per year

1973 2020

• 23823 Citations
• 236 Article
• 35 Review article
• 10 Comment/debate
• 3 Short survey
• 5 More
  • 2 Chapter
  • 2 Letter
  • 1 Editorial

Research Output per year

Research Output per year

Search results

• 2020

  Blood natural killer cell deficiency reveals an immunotherapy strategy for atopic dermatitis

  Mack, M. R., Brestoff, J. R., Berrien-Elliott, M. M., Trier, A. M., Yang, T. L. B., McCullen, M., Collins, P. L., Niu, H., Bodet, N. D., Wagner, J. A., Park, E., Xu, A. Z., Wang, F., Chibnall, R., Council, M. L., Heffington, C., Kreisel, F., Margolis, D. J., Sheinbein, D., Lovato, P. & 7 others, Vivier, E., Cella, M., Colonna, M., Yokoyama, W. M., Oltz, E. M., Fehniger, T. A. & Kim, B. S., Feb 26 2020, In: Science translational medicine. 12, 532, aay1005.

  Research output: Contribution to journal › Article › peer-review

  • GATA2 Deficiency
  • Atopic Dermatitis
  • Immunotherapy
  • Blood Cells
  • Interleukin-15
  8 Scopus citations

• cDC1 prime and are licensed by CD4⁺ T cells to induce anti-tumour immunity

  Ferris, S. T., Durai, V., Wu, R., Theisen, D. J., Ward, J. P., Bern, M. D., Davidson, J. T., Bagadia, P., Liu, T., Briseño, C. G., Li, L., Gillanders, W. E., Wu, G. F., Yokoyama, W. M., Murphy, T. L., Schreiber, R. D. & Murphy, K. M., Aug 27 2020, In: Nature. 584, 7822, p. 624-629 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Immunity
  • T-Lymphocytes
  • Neoplasms
  • Antigen Presentation
  • Licensure
  7 Scopus citations

• Control of Viral Infection by Natural Killer Cell Inhibitory Receptors

  Parikh, B. A., Bern, M. D., Piersma, S. J., Yang, L., Beckman, D. L., Poursine-Laurent, J., Plougastel-Douglas, B. & Yokoyama, W. M., Jul 28 2020, In: Cell Reports. 32, 4, 107969.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Natural Killer Cell Receptors
  • Major Histocompatibility Complex
  • Virus Diseases
  • Muromegalovirus
  • Natural Killer Cells

• T cell response kinetics determines neuroinfection outcomes during murine HSV infection

  Lee, A. G., Scott, J. M., Fabbrizi, M. R., Jiang, X., Sojka, D. K., Miller, M. J., Baldridge, M. T., Yokoyama, W. M. & Shin, H., Mar 12 2020, In: JCI Insight. 5, 5, e134258.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Human Herpesvirus 1
  • Human Herpesvirus 2
  • Herpes Genitalis
  • Kinetics
  • T-Lymphocytes

• Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through sting

  Piersma, S. J., Poursine-Laurent, J., Yang, L., Barber, G. N., Parikh, B. A. & Yokoyama, W. M., Jul 2020, In: eLife. 9, p. 1-21 21 p., e56882.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Muromegalovirus
  • Viruses
  • Bites and Stings
  • Stromal Cells
  • Virus Diseases
  1 Scopus citations
• 2019

  Activation receptor–dependent IFN-g production by NK cells is controlled by transcription, translation, and the proteasome

  Piersma, S. J., Pak-Wittel, M. A., Lin, A., Plougastel-Douglas, B. & Yokoyama, W. M., Oct 1 2019, In: Journal of Immunology. 203, 7, p. 1981-1988 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Proteasome Endopeptidase Complex
  • Natural Killer Cells
  • Cytokines
  • Oncogenic Viruses
  • Interleukin-12
  4 Scopus citations

• Cowpox virus encodes a protein that binds B7.1 and B7.2 and subverts T cell costimulation

  Wang, X., Piersma, S. J., Elliott, J. I., Errico, J. M., Gainey, M. D., Yang, L., Nelson, C. A., Yokoyama, W. M. & Fremont, D. H., Oct 15 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 42, p. 21113-21119 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cowpox virus
  • T-Lymphocytes
  • Poxviridae Infections
  • Proteins
  • Ligands

• First-onset herpesviral infection and lung injury in allogeneic hematopoietic cell transplantation

  Zhou, X., O'Dwyer, D. N., Xia, M., Miller, H. K., Chan, P. R., Trulik, K., Chadwick, M. M., Hoffman, T. C., Bulte, C., Sekerak, K., Wilke, C. A., Patel, S. J., Yokoyama, W. M., Murray, S., Yanik, G. A. & Moore, B. B., Jan 1 2019, In: American journal of respiratory and critical care medicine. 200, 1, p. 63-74 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell Transplantation
  • Allogeneic Cells
  • Lung Injury
  • Roseolovirus
  • Transplants
  12 Scopus citations

• Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis

  Ardain, A., Domingo-Gonzalez, R., Das, S., Kazer, S. W., Howard, N. C., Singh, A., Ahmed, M., Nhamoyebonde, S., Rangel-Moreno, J., Ogongo, P., Lu, L., Ramsuran, D., de la Luz Garcia-Hernandez, M., K. Ulland, T., Darby, M., Park, E., Karim, F., Melocchi, L., Madansein, R., Dullabh, K. J. & 16 others, Dunlap, M., Marin-Agudelo, N., Ebihara, T., Ndung’u, T., Kaushal, D., Pym, A. S., Kolls, J. K., Steyn, A., Zúñiga, J., Horsnell, W., Yokoyama, W. M., Shalek, A. K., Kløverpris, H. N., Colonna, M., Leslie, A. & Khader, S. A., Jun 27 2019, In: Nature. 570, 7762, p. 528-532 5 p.

  Research output: Contribution to journal › Article › peer-review

  • CXC Chemokines
  • Tuberculosis
  • Immunity
  • Lymphocytes
  • Mycobacterium tuberculosis
  39 Scopus citations

• Inducible down-regulation of MHC class I results in natural killer cell tolerance

  Bern, M. D., Parikh, B. A., Yang, L., Beckman, D. L., Poursine‑Laurent, J. & Yokoyama, W. M., Jan 1 2019, In: Journal of Experimental Medicine. 216, 1, p. 99-116 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Natural Killer Cells
  • Down-Regulation
  • Inflammation
  • Lymphocytes
  • T-Lymphocytes
  11 Scopus citations

• In the absence of natural killer cell activation donor-specific antibody mediates chronic, but not acute, kidney allograft rejection

  Yagisawa, T., Tanaka, T., Miyairi, S., Tanabe, K., Dvorina, N., Yokoyama, W. M., Valujskikh, A., Baldwin, W. M. & Fairchild, R. L., Feb 2019, In: Kidney International. 95, 2, p. 350-362 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Natural Killer Cells
  • Allografts
  • Transplants
  • Antibodies
  • Kidney
  4 Scopus citations

• Long-term correction of hemophilia B using adenoviral delivery of CRISPR/Cas9

  Stephens, C. J., Lauron, E. J., Kashentseva, E., Lu, Z. H., Yokoyama, W. M. & Curiel, D. T., Mar 28 2019, In: Journal of Controlled Release. 298, p. 128-141 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hemophilia B
  • Clustered Regularly Interspaced Short Palindromic Repeats
  • Adenoviridae
  • Genetic Therapy
  • Gene Knock-In Techniques
  20 Scopus citations

• Toxoplasma gondii effector TgIST blocks type I interferon signaling to promote infection

  Matta, S. K., Olias, P., Huang, Z., Wang, Q., Park, E., Yokoyama, W. M. & Sibley, L. D., Aug 27 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 35, p. 17480-17491 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Interferon Type I
  • Toxoplasma
  • Interferons
  • Interferon-gamma
  • Parasites
  8 Scopus citations

• Toxoplasma gondii infection drives conversion of NK cells into ILC1-like cells

  Park, E., Patel, S., Wang, Q., Andhey, P., Zaitsev, K., Porter, S., Hershey, M., Bern, M., Plougastel-Douglas, B., Collins, P., Colonna, M., Murphy, K. M., Oltz, E., Artyomov, M., Sibley, L. D. & Yokoyama, W. M., Aug 2019, In: eLife. 8, e47605.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Toxoplasmosis
  • Tumors
  • Natural Killer Cells
  • Cytokines
  • Lymphocytes
  20 Scopus citations

• ZBTB32 restrains antibody responses to murine cytomegalovirus infections, but not other repetitive challenges

  Jash, A., Zhou, Y. W., Gerardo, D. K., Ripperger, T. J., Parikh, B. A., Piersma, S., Jamwal, D. R., Kiela, P. R., Boon, A. C. M., Yokoyama, W. M., Hsieh, C. S. & Bhattacharya, D., Dec 1 2019, In: Scientific reports. 9, 1, 15257.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Muromegalovirus
  • Cytomegalovirus Infections
  • Antibody Formation
  • B-Lymphocytes
  • Infection
  3 Scopus citations
• 2018

  A herpesvirus encoded Qa-1 mimic inhibits natural killer cell cytotoxicity through CD94/NKG2A receptor engagement

  Wang, X., Piersma, S. J., Nelson, C. A., Dai, Y. N., Christensen, T., Lazear, E., Yang, L., Sluijter, M., van Hall, T., Hansen, T. H., Yokoyama, W. M. & Fremont, D. H., Dec 1 2018, In: eLife. 7, e38667.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • NK Cell Lectin-Like Receptor Subfamily C
  • Cytotoxicity
  • Peru
  • Herpesviridae
  • Natural Killer Cells
  1 Scopus citations

• Cross-priming induces immunodomination in the presence of viral MHC class I inhibition

  Lauron, E. J., Yang, L., Elliott, J. I., Gainey, M. D., Fremont, D. H. & Yokoyama, W. M., Feb 2018, In: PLoS pathogens. 14, 2, e1006883.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cowpox virus
  • Cross-Priming
  • T-Lymphocytes
  • Poxviridae
  • Epitopes
  6 Scopus citations

• Cutting edge: Local proliferation of uterine tissue-resident NK cells during decidualization in mice

  Sojka, D. K., Yang, L., Plougastel-Douglas, B., Higuchi, D. A., Anne Croy, B. & Yokoyama, W. M., Nov 1 2018, In: Journal of Immunology. 201, 9, p. 2551-2556 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Natural Killer Cells
  • Uterus
  • Deciduoma
  • Parabiosis
  • Decidua
  23 Scopus citations

• WDFY4 is required for cross-presentation in response to viral and tumor antigens

  Theisen, D. J., Davidson, J. T., Briseño, C. G., Gargaro, M., Lauron, E. J., Wang, Q., Desai, P., Durai, V., Bagadia, P., Brickner, J. R., Beatty, W. L., Virgin, H. W., Gillanders, W. E., Mosammaparast, N., Diamond, M. S., Sibley, L. D., Yokoyama, W., Schreiber, R. D., Murphy, T. L. & Murphy, K. M., Nov 9 2018, In: Science. 362, 6415, p. 694-699 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Cross-Priming
  • Viral Tumor Antigens
  • Dendritic Cells
  • T-Lymphocytes
  • Clustered Regularly Interspaced Short Palindromic Repeats
  54 Scopus citations
• 2017

  A murine herpesvirus closely related to ubiquitous human herpesviruses causes T-cell depletion

  Patel, S. J., Zhao, G., Penna, V. R., Park, E., Lauron, E. J., Harvey, I. B., Beatty, W. L., Plougastel-Douglas, B., Poursine-Laurent, J., Fremont, D. H., Wang, D. & Yokoyama, W. M., May 1 2017, In: Journal of virology. 91, 9, e02463-16.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Roseolovirus
  • Human Herpesvirus 6
  • Herpesviridae
  • T-lymphocytes
  • Human herpesvirus 7
  19 Scopus citations

• CD8+ T cells prevent lethality from neonatal murine roseolovirus infection

  Patel, S. J. & Yokoyama, W. M., Nov 1 2017, In: Journal of Immunology. 199, 9, p. 3212-3221 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Roseolovirus Infections
  • Roseolovirus
  • T-Lymphocytes
  • Thymocytes
  • Infection
  2 Scopus citations

• Contribution of inhibitory receptor TIGIT to NK cell education

  He, Y., Peng, H., Sun, R., Wei, H., Ljunggren, H. G., Yokoyama, W. M. & Tian, Z., Jul 2017, In: Journal of Autoimmunity. 81, p. 1-12 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Natural Killer Cells
  • Education
  • Ligands
  • Histocompatibility Antigens Class I
  20 Scopus citations

• Cutting edge: Human CD49e^- NK cells are tissue resident in the liver

  Aw Yeang, H. X., Piersma, S. J., Lin, Y., Yang, L., Malkova, O. N., Miner, C., Krupnick, A. S., Chapman, W. C. & Yokoyama, W. M., Feb 15 2017, In: Journal of Immunology. 198, 4, p. 1417-1422 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Natural Killer Cells
  • Liver
  • Spleen
  • Transcription Factors
  39 Scopus citations

• Immunoreceptor tyrosine-based inhibitory motif–dependent functions of an MHC class I-specific NK cell receptor

  Bern, M. D., Beckman, D. L., Ebihara, T., Taffner, S. M., Poursine-Laurent, J., White, J. M. & Yokoyama, W. M., Oct 3 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 40, p. E8440-E8447

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Natural Killer Cell Receptors
  • Natural Killer Cells
  • Tyrosine
  • Licensure
  • Mutation
  10 Scopus citations

• Natural killer cells attenuate cytomegalovirus-induced hearing loss in mice

  Almishaal, A. A., Mathur, P. D., Hillas, E., Chen, L., Zhang, A., Yang, J., Wang, Y., Yokoyama, W. M., Firpo, M. A. & Park, A. H., Aug 2017, In: PLoS pathogens. 13, 8, e1006599.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cytomegalovirus
  • Hearing Loss
  • Natural Killer Cells
  • Sensorineural Hearing Loss
  • Labyrinthitis
  9 Scopus citations

• Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression

  Zhu, Y., Herndon, J. M., Sojka, D. K., Kim, K. W., Knolhoff, B. L., Zuo, C., Cullinan, D. R., Luo, J., Bearden, A. R., Lavine, K. J., Yokoyama, W. M., Hawkins, W. G., Fields, R. C., Randolph, G. J. & DeNardo, D. G., Aug 15 2017, In: Immunity. 47, 2, p. 323-338.e6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hematopoiesis
  • Adenocarcinoma
  • Macrophages
  • Neoplasms
  • Monocytes
  150 Scopus citations
• 2016

  Deficiency of the adaptor protein SLy1 results in a natural killer cell ribosomopathy affecting tumor clearance

  Arefanian, S., Schäll, D., Chang, S., Ghasemi, R., Higashikubo, R., Zheleznyak, A., Guo, Y., Yu, J., Asgharian, H., Li, W., Gelman, A. E., Kreisel, D., French, A. R., Zaher, H., Plougastel-Douglas, B., Maggi, L., Yokoyama, W., Beer-Hammer, S. & Krupnick, A. S., Dec 1 2016, In: OncoImmunology. 5, 12, e1238543.

  Research output: Contribution to journal › Article › peer-review

  • Protein Deficiency
  • Natural Killer Cells
  • Cytoplasm
  • Neoplasms
  • Ribosomal Proteins
  3 Scopus citations

• Differential phenotypic and functional properties of liver-resident NK cells and mucosal ILC1s

  Tang, L., Peng, H., Zhou, J., Chen, Y., Wei, H., Sun, R., Yokoyama, W. M. & Tian, Z., Feb 1 2016, In: Journal of Autoimmunity. 67, p. 29-35 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Natural Killer Cells
  • Liver
  • Lymphocytes
  • Contact Dermatitis
  • Internship and Residency
  57 Scopus citations

• Thymic stromal lymphopoietin blocks early stages of breast carcinogenesis

  Demehri, S., Cunningham, T. J., Manivasagam, S., Ngo, K. H., Tuchayi, S. M., Reddy, R., Meyers, M. A., DeNardo, D. G. & Yokoyama, W. M., Apr 1 2016, In: Journal of Clinical Investigation. 126, 4, p. 1458-1470 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • thymic stromal lymphopoietin
  • Carcinogenesis
  • Breast
  • Th2 Cells
  • Immunity
  28 Scopus citations
• 2015

  Brief report: Chikungunya viral arthritis in the United States: A mimic of seronegative rheumatoid arthritis

  Miner, J. J., Yeang, H. X. A., Fox, J. M., Taffner, S., Malkova, O. N., Oh, S. T., Kim, A. H. J., Diamond, M. S., Lenschow, D. J. & Yokoyama, W. M., May 1 2015, In: Arthritis and Rheumatology. 67, 5, p. 1214-1220 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Chikungunya virus
  • Infectious Arthritis
  • Rheumatoid Arthritis
  • Arthritis
  • Chikungunya Fever
  79 Scopus citations

• Detailed phenotypic and molecular analyses of genetically modified mice generated by CRISPR-Cas9-mediated editing

  Parikh, B. A., Beckman, D. L., Patel, S. J., White, J. M. & Yokoyama, W. M., Jan 14 2015, In: PloS one. 10, 1, e0116484.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Clustered Regularly Interspaced Short Palindromic Repeats
  • Genes
  • gene editing
  • Gene Editing
  • Guide RNA
  29 Scopus citations

• Dual Requirement of Cytokine and Activation Receptor Triggering for Cytotoxic Control of Murine Cytomegalovirus by NK Cells

  Parikh, B. A., Piersma, S. J., Pak-Wittel, M. A., Yang, L., Schreiber, R. D. & Yokoyama, W. M., 2015, In: PLoS pathogens. 11, 12, e1005323.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Muromegalovirus
  • Cytokine Receptors
  • Natural Killer Cells
  • Natural Killer Cell Receptors
  • Granzymes
  18 Scopus citations

• PTEN regulates natural killer cell trafficking in vivo

  Leong, J. W., Schneider, S. E., Sullivan, R. P., Parikh, B. A., Anthony, B. A., Singh, A., Jewell, B. A., Schappe, T., Wagner, J. A., Link, D. C., Yokoyama, W. M. & Fehniger, T. A., Feb 17 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 7, p. E700-E709

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Tensins
  • Phosphoric Monoester Hydrolases
  • Natural Killer Cells
  • Bone Marrow
  • Neoplasms
  22 Scopus citations

• Runx3 specifies lineage commitment of innate lymphoid cells

  Ebihara, T., Song, C., Ryu, S. H., Plougastel-Douglas, B., Yang, L., Levanon, D., Groner, Y., Bern, M. D., Stappenbeck, T. S., Colonna, M., Egawa, T. & Yokoyama, W. M., Oct 20 2015, In: Nature immunology. 16, 11, p. 1124-1133 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Lymphocytes
  • Transcription Factors
  • Citrobacter rodentium
  • Cell Lineage
  • Mucous Membrane
  83 Scopus citations

• The Inhibitory Receptor NKG2A Sustains Virus-Specific CD8⁺ T Cells in Response to a Lethal Poxvirus Infection

  Rapaport, A. S., Schriewer, J., Gilfillan, S., Hembrador, E., Crump, R., Plougastel, B. F., Wang, Y., Le Friec, G., Gao, J., Cella, M., Pircher, H., Yokoyama, W. M., Buller, R. M. L. & Colonna, M., 2015, In: Immunity. 43, 6, p. 1112-1124 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • NK Cell Lectin-Like Receptor Subfamily C
  • Poxviridae Infections
  • Viruses
  • T-Lymphocytes
  • Ectromelia virus
  30 Scopus citations

• The pancreas anatomy conditions the origin and properties of resident macrophages

  Calderon, B., Carrero, J. A., Ferris, S. T., Sojka, D. K., Moore, L., Epelman, S., Murphy, K. M., Yokoyama, W. M., Randolph, G. J. & Unanue, E. R., Sep 21 2015, In: Journal of Experimental Medicine. 212, 10, p. 1497-1512 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pancreas
  • Anatomy
  • Macrophages
  • Hematopoiesis
  • Myeloid Cells
  102 Scopus citations

• Tissue-resident NK cells mediate ischemic kidney injury and are not depleted by anti-asialo-GM1 antibody

  Victorino, F., Sojka, D. K., Brodsky, K. S., McNamee, E. N., Masterson, J. C., Homann, D., Yokoyama, W. M., Eltzschig, H. K. & Clambey, E. T., Nov 15 2015, In: Journal of Immunology. 195, 10, p. 4973-4985 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • asialo GM1 ganglioside
  • Natural Killer Cells
  • Antibodies
  • Kidney
  • Wounds and Injuries
  57 Scopus citations
• 2014

  Chronic allergic contact dermatitis promotes skin cancer

  Demehri, S., Cunningham, T. J., Hurst, E. A., Schaffer, A., Sheinbein, D. M. & Yokoyama, W. M., Nov 3 2014, In: Journal of Clinical Investigation. 124, 11, p. 5037-5041 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Allergic Contact Dermatitis
  • Skin Neoplasms
  • Skin
  • Dinitrofluorobenzene
  • Squamous Cell Carcinoma
  13 Scopus citations

• Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation

  Epelman, S., Lavine, K. J., Beaudin, A. E., Sojka, D. K., Carrero, J. A., Calderon, B., Brija, T., Gautier, E. L., Ivanov, S., Satpathy, A. T., Schilling, J. D., Schwendener, R., Sergin, I., Razani, B., Forsberg, E. C., Yokoyama, W. M., Unanue, E. R., Colonna, M., Randolph, G. J. & Mann, D. L., Jan 16 2014, In: Immunity. 40, 1, p. 91-104 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Macrophages
  • Inflammation
  • Yolk Sac
  • Monocytes
  • Population
  589 Scopus citations

• Ischemic neurons recruit natural killer cells that accelerate brain infarction

  Gan, Y., Liu, Q., Wu, W., Yin, J. X., Bai, X. F., Shen, R., Wang, Y., Chen, J., Cava, A. L., Poursine-Laurent, J., Yokoyama, W. & Shi, F. D., Feb 18 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 7, p. 2704-2709 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Brain Infarction
  • Natural Killer Cells
  • Neurons
  • Brain Ischemia
  • Brain
  110 Scopus citations

• Isolation of murine natural killer cells

  Pak-Wittel, M. A., Piersma, S. J., Plougastel, B. F., Poursine-Laurent, J. & Yokoyama, W. M., Jan 1 2014, In: Current Protocols in Immunology. SUPPL.105, 3.22.

  Research output: Contribution to journal › Article › peer-review

  • Natural Killer Cells
  • Spleen
  • Antibodies
  • Flow Cytometry
  • Monoclonal Antibodies
  3 Scopus citations

• Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

  Schoggins, J. W., MacDuff, D. A., Imanaka, N., Gainey, M. D., Shrestha, B., Eitson, J. L., Mar, K. B., Richardson, R. B., Ratushny, A. V., Litvak, V., Dabelic, R., Manicassamy, B., Aitchison, J. D., Aderem, A., Elliott, R. M., García-Sastre, A., Racaniello, V., Snijder, E. J., Yokoyama, W. M., Diamond, M. S. & 2 others, Virgin, H. W. & Rice, C. M., 2014, In: Nature. 505, 7485, p. 691-695 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Innate Immunity
  • Interferons
  • RNA Viruses
  • Antiviral Agents
  • Viruses
  458 Scopus citations

• Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells

  Sojka, D. K., Plougastel-Douglas, B., Yang, L., Pak-Wittel, M. A., Artyomov, M. N., Ivanova, Y., Zhong, C., Chase, J. M., Rothman, P. B., Yu, J., Riley, J. K., Zhu, J., Tian, Z. & Yokoyama, W. M., Apr 8 2014, In: eLife. 2014, 3, e01659.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cell Lineage
  • Natural Killer Cells
  • Tissue
  • Liver
  • Cytotoxicity
  288 Scopus citations
• 2013

  Inositol tetrakisphosphate limits NK cell effector functions by controlling PI3K signaling

  Sauer, K., Park, E., Siegemund, S., French, A. R., Wahle, J. A., Sternberg, L., Rigaud, S., Jonsson, A. H., Yokoyama, W. M. & Huang, Y. H., Jan 10 2013, In: Blood. 121, 2, p. 286-297 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Natural Killer Cell Receptors
  • Inositol
  • Phosphatidylinositol 3-Kinases
  • Natural Killer Cells
  • Tissue homeostasis
  14 Scopus citations

• Interferon-γ mediates chemokine-dependent recruitment of natural killer cells during viral infection

  Pak-Wittel, M. A., Yang, L., Sojka, D. K., Rivenbark, J. G. & Yokoyama, W. M., Jan 2 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 1, p. E50-E59

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Chemokines
  • Natural Killer Cells
  • Interferons
  • Virus Diseases
  • Cowpox virus
  63 Scopus citations

• Liver-resident NK cells confer adaptive immunity in skin-contact inflammation

  Peng, H., Jiang, X., Chen, Y., Sojka, D. K., Wei, H., Gao, X., Sun, R., Yokoyama, W. M. & Tian, Z., Apr 1 2013, In: Journal of Clinical Investigation. 123, 4, p. 1444-1456 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adaptive Immunity
  • Natural Killer Cells
  • Inflammation
  • Skin
  • Liver
  299 Scopus citations

• Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes

  Jakubzick, C., Gautier, E. L., Gibbings, S. L., Sojka, D. K., Schlitzer, A., Johnson, T. E., Ivanov, S., Duan, Q., Bala, S., Condon, T., vanRooijen, N., Grainger, J. R., Belkaid, Y., Ma'ayan, A., Riches, D. W. H., Yokoyama, W. M., Ginhoux, F., Henson, P. M. & Randolph, G. J., Sep 19 2013, In: Immunity. 39, 3, p. 599-610 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Monocytes
  • Lymph Nodes
  • Antigens
  • Dendritic Cells
  • Macrophages
  393 Scopus citations

• Murine cytomegalovirus protein pM79 is a key regulator for viral late transcription

  Chapa, T. J., Steven Johnson, L., Affolter, C., Valentine Mark C., M. C., Fehr, A. R., Yokoyama, W. M. & Yu, D., Aug 2013, In: Journal of virology. 87, 16, p. 9135-9147 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Muromegalovirus
  • Cytomegalovirus
  • Viral DNA
  • transcription (genetics)
  • mice
  13 Scopus citations

• Natural killer cell licensing in mice with inducible expression of MHC class I

  Ebihara, T., Jonsson, A. H. & Yokoyama, W. M., Nov 5 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 45, p. E4232-E4237

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Licensure
  • Natural Killer Cells
  • Ovalbumin
  • Stromal Cells
  • Spleen
  29 Scopus citations

• Production of monoclonal antibodies

  Yokoyama, W. M., Christensen, M., Santos, G. D., Miller, D., Ho, J., Wu, T., Dziegelewski, M. & Neethling, F. A., 2013, In: Current Protocols in Immunology. SUPPL.102, 2.5.

  Research output: Contribution to journal › Article › peer-review

  • Hybridomas
  • Organism Cloning
  • Cell Fusion
  • Monoclonal Antibodies
  • Antibody Specificity
  32 Scopus citations