Research output per year
Research output per year
- 1 - 50 out of 313 results
Search results
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2025
Expression of a single inhibitory member of the Ly49 receptor family is sufficient to license NK cells for effector functions
Piersma, S. J., Li, S., Wong, P., Bern, M. D., Poursine-Laurent, J., Yang, L., Beckman, D. L., Parikh, B. A. & Yokoyama, W. M., Mar 14 2025, In: eLife. 13Research output: Contribution to journal › Article › peer-review
Open Access -
Shared pathway of WDFY4-dependent cross-presentation of immune complexes by cDC1 and cDC2
Jo, S., Ohara, R. A., Theisen, D. J., Kim, S., Liu, T., Bullock, C. B., He, M., Ou, F., Chen, J., Piersma, S. J., Postoak, J. L., Yokoyama, W. M., Diamond, M. S., Murphy, T. L. & Murphy, K. M., Apr 7 2025, In: The Journal of experimental medicine. 222, 4Research output: Contribution to journal › Article › peer-review
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2024
Cis-regulatory evolution of the recently expanded Ly49 gene family
Fan, C., Xing, X., Murphy, S. J. H., Poursine-Laurent, J., Schmidt, H., Parikh, B. A., Yoon, J., Choudhary, M. N. K., Saligrama, N., Piersma, S. J., Yokoyama, W. M. & Wang, T., Dec 2024, In: Nature communications. 15, 1, 4839.Research output: Contribution to journal › Article › peer-review
Open Access -
Innate Lymphoid Cells and Natural Killer Cells
Paley, M. & Yokoyama, W., Jan 1 2024, Firestein & Kelley's Textbook of Rheumatology, 2-Volume Set. Elsevier, Vol. 2. p. 265-272 8 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Mucosal signatures of pathogenic T cells in HLA-B*27+ anterior uveitis and axial spondyloarthritis
Paley, M. A., Yang, X., Hassman, L. M., Penkava, F., Garner, L. I., Paley, G. L., Linskey, N., Agnew, R., Faria, P. H. A. D., Feng, A., Li, S. Y., Simone, D., Roberson, E. D. O., Ruzycki, P. A., Esaulova, E., Laurent, J., Feigl-Lenzen, L., Springer, L. E., Liu, C. & Gillespie, G. M. & 3 others, , Aug 22 2024, In: JCI Insight. 9, 16, e174776.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
2023
Corrigendum: Intraocular human cytomegaloviruses of ocular diseases are distinct from those of viremia and are capable of escaping from innate and adaptive immunity by exploiting HLA-E-mediated peripheral and central tolerance(Front. Immunol., (2022), 13, (1008220), 10.3389/fimmu.2022.1008220)
Shirane, M., Yawata, N., Motooka, D., Shibata, K., Khor, S. S., Omae, Y., Kaburaki, T., Yanai, R., Mashimo, H., Yamana, S., Ito, T., Hayashida, A., Mori, Y., Numata, A., Murakami, Y., Fujiwara, K., Ohguro, N., Hosogai, M., Akiyama, M. & Hasegawa, E. & 8 others, , Jan 5 2023, In: Frontiers in immunology. 13, 1124440.Research output: Contribution to journal › Comment/debate
Open Access -
Emil R. Unanue (1934-2022)
Yokoyama, W. M., Murphy, K., Schreiber, R. & Colonna, M., Feb 14 2023, In: Immunity. 56, 2, p. 225-226 2 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Fibrosis induced by resident macrophages has divergent roles in pancreas inflammatory injury and PDAC
Baer, J. M., Zuo, C., Kang, L. I., de la Lastra, A. A., Borcherding, N. C., Knolhoff, B. L., Bogner, S. J., Zhu, Y., Yang, L., Laurent, J., Lewis, M. A., Zhang, N., Kim, K. W., Fields, R. C., Yokoyama, W. M., Mills, J. C., Ding, L., Randolph, G. J. & DeNardo, D. G., Sep 2023, In: Nature immunology. 24, 9, p. 1443-1457 15 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
NK cell expansion requires HuR and mediates control of solid tumors and long-term virus infection
Piersma, S. J., Bangru, S., Yoon, J., Liu, T. W., Yang, L., Hsieh, C. S., Plougastel-Douglas, B., Kalsotra, A. & Yokoyama, W. M., 2023, In: Journal of Experimental Medicine. 220, 11, e20231154.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Perinatal murine cytomegalovirus infection reshapes the transcriptional profile and functionality of NK cells
Rožmanić, C., Lisnić, B., Pribanić Matešić, M., Mihalić, A., Hiršl, L., Park, E., Lesac Brizić, A., Indenbirken, D., Viduka, I., Šantić, M., Adler, B., Yokoyama, W. M., Krmpotić, A., Juranić Lisnić, V., Jonjić, S. & Brizić, I., Dec 2023, In: Nature communications. 14, 1, 6412.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2022
Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides
Yang, X., Garner, L. I., Zvyagin, I. V., Paley, M. A., Komech, E. A., Jude, K. M., Zhao, X., Fernandes, R. A., Hassman, L. M., Paley, G. L., Savvides, C. S., Brackenridge, S., Quastel, M. N., Chudakov, D. M., Bowness, P., Yokoyama, W. M., McMichael, A. J., Gillespie, G. M. & Garcia, K. C., Dec 22 2022, In: Nature. 612, 7941, p. 771-777 7 p.Research output: Contribution to journal › Article › peer-review
Open Access77 Scopus citations -
Disruption of thymic central tolerance by infection with murine roseolovirus induces autoimmune gastritis
Bigley, T. M., Yang, L., Kang, L. I., Saenz, J. B., Victorino, F. & Yokoyama, W. M., Mar 7 2022, In: Journal of Experimental Medicine. 219, 3, e20211403.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Human NK cells confer protection against HIV-1 infection in humanized mice
Sungur, C. M., Wang, Q., Ozantürk, A. N., Gao, H., Schmitz, A. J., Cella, M., Yokoyama, W. M. & Shan, L., Dec 15 2022, In: Journal of Clinical Investigation. 132, 24, e162694.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Intraocular human cytomegaloviruses of ocular diseases are distinct from those of viremia and are capable of escaping from innate and adaptive immunity by exploiting HLA-E-mediated peripheral and central tolerance
Shirane, M., Yawata, N., Motooka, D., Shibata, K., Khor, S. S., Omae, Y., Kaburaki, T., Yanai, R., Mashimo, H., Yamana, S., Ito, T., Hayashida, A., Mori, Y., Numata, A., Murakami, Y., Fujiwara, K., Ohguro, N., Hosogai, M., Akiyama, M. & Hasegawa, E. & 8 others, , Oct 19 2022, In: Frontiers in immunology. 13, 1008220.Research output: Contribution to journal › Article › peer-review
Open Access -
Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains
Bigley, T. M., Xiong, M., Ali, M., Chen, Y., Wang, C., Serrano, J. R., Eteleeb, A., Harari, O., Yang, L., Patel, S. J., Cruchaga, C., Yokoyama, W. M. & Holtzman, D. M., Dec 2022, In: Molecular neurodegeneration. 17, 1, 10.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
NK Cells and ILC1s in Cancer Biology
Sliz, A. & Yokoyama, W. M., 2022, Advances in Experimental Medicine and Biology. Springer, p. 41-55 15 p. (Advances in Experimental Medicine and Biology; vol. 1365).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
2 Scopus citations -
The CSF in neurosarcoidosis contains consistent clonal expansion of CD8 T cells, but not CD4 T cells
Paley, M. A., Baker, B. J., Dunham, S. R., Linskey, N., Cantoni, C., Lee, K., Hassman, L. M., Laurent, J., Roberson, E. D. O., Clifford, D. B. & Yokoyama, W. M., Jun 15 2022, In: Journal of Neuroimmunology. 367, 577860.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
The transcription factor Bach2 negatively regulates murine natural killer cell maturation and function
Li, S., Bern, M. D., Miao, B., Fan, C., Xing, X., Inoue, T., Piersma, S. J., Wang, T., Colonna, M., Kurosaki, T. & Yokoyama, W. M., 2022, In: eLife. 11, e77294.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
2021
Clinicomolecular Identification of Conserved and Individualized Features of Granulomatous Uveitis
Hassman, L. M., Paley, M. A., Esaulova, E., Paley, G. L., Ruzycki, P. A., Linskey, N., Laurent, J., Feigl-Lenzen, L., Springer, L., Montana, C. L., Hong, K., Enright, J., James, H., Artyomov, M. N. & Yokoyama, W. M., Mar 2021, In: Ophthalmology Science. 1, 1, 100010.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Hif1α is required for nk cell metabolic adaptation during virus infection
Victorino, F., Bigley, T. M., Park, E., Yao, C. H., Benoit, J., Yang, L. P., Piersma, S. J., Lauron, E. J., Davidson, R. M., Patti, G. J. & Yokoyama, W. M., Aug 2021, In: eLife. 10, e68484.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Hobit confers tissue-dependent programs to type 1 innate lymphoid cells
Yomogida, K., Bigley, T. M., Trsan, T., Gilfillan, S., Cella, M., Yokoyama, W. M., Egawa, T. & Colonna, M., Dec 14 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 50, e2117965118.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
Identification of a t-bethi quiescent exhausted cd8 t cell subpopulation that can differentiate into tim3+cx3cr1+ effectors and memory-like cells
Raju, S., Xia, Y., Daniel, B., Yost, K. E., Bradshaw, E., Tonc, E., Verbaro, D. J., Kometani, K., Yokoyama, W. M., Kurosaki, T., Satpathy, A. T. & Egawa, T., Jun 15 2021, In: Journal of Immunology. 206, 12, p. 2924-2936 13 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Immunology Lessons from the SARS-CoV-2 Pandemic
Yokoyama, W. M., Hogquist, K. A. & O'Shea, J. J., Apr 26 2021, In: Annual Review of Immunology. 39, p. V-VIIResearch output: Contribution to journal › Editorial
1 Scopus citations -
Innovations in MD-only physician-scientist training: Experiences from the Burroughs Wellcome Fund physician-scientist institutional award initiative
McElvaine, A. T., Hawkins-Salsbury, J. A., Arora, V. M., Gladwin, M. T., Goldenring, J. R., Huston, D. P., Krakow, D., Rhee, K., Solway, J., Steinman, R. A., Towler, D. A., Utz, P. J., Yokoyama, W. M., Simpson, R. L., Muglia, L. J., Permar, S. R. & Gbadegesin, R. A., May 2021, In: Journal of Clinical Investigation. 131, 10, e149948.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2020
Blood natural killer cell deficiency reveals an immunotherapy strategy for atopic dermatitis
Mack, M. R., Brestoff, J. R., Berrien-Elliott, M. M., Trier, A. M., Yang, T. L. B., McCullen, M., Collins, P. L., Niu, H., Bodet, N. D., Wagner, J. A., Park, E., Xu, A. Z., Wang, F., Chibnall, R., Council, M. L., Heffington, C., Kreisel, F., Margolis, D. J., Sheinbein, D. & Lovato, P. & 7 others, , Feb 26 2020, In: Science translational medicine. 12, 532, aay1005.Research output: Contribution to journal › Article › peer-review
Open Access79 Scopus citations -
cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity
Ferris, S. T., Durai, V., Wu, R., Theisen, D. J., Ward, J. P., Bern, M. D., Davidson, J. T., Bagadia, P., Liu, T., Briseño, C. G., Li, L., Gillanders, W. E., Wu, G. F., Yokoyama, W. M., Murphy, T. L., Schreiber, R. D. & Murphy, K. M., Aug 27 2020, In: Nature. 584, 7822, p. 624-629 6 p.Research output: Contribution to journal › Article › peer-review
Open Access351 Scopus citations -
Control of Viral Infection by Natural Killer Cell Inhibitory Receptors
Parikh, B. A., Bern, M. D., Piersma, S. J., Yang, L., Beckman, D. L., Poursine-Laurent, J., Plougastel-Douglas, B. & Yokoyama, W. M., Jul 28 2020, In: Cell Reports. 32, 4, 107969.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
T cell response kinetics determines neuroinfection outcomes during murine HSV infection
Lee, A. G., Scott, J. M., Fabbrizi, M. R., Jiang, X., Sojka, D. K., Miller, M. J., Baldridge, M. T., Yokoyama, W. M. & Shin, H., Mar 12 2020, In: JCI Insight. 5, 5, e134258.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through sting
Piersma, S. J., Poursine-Laurent, J., Yang, L., Barber, G. N., Parikh, B. A. & Yokoyama, W. M., Jul 2020, In: eLife. 9, p. 1-21 21 p., e56882.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
2019
Activation receptor–dependent IFN-g production by NK cells is controlled by transcription, translation, and the proteasome
Piersma, S. J., Pak-Wittel, M. A., Lin, A., Plougastel-Douglas, B. & Yokoyama, W. M., Oct 1 2019, In: Journal of Immunology. 203, 7, p. 1981-1988 8 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Cowpox virus encodes a protein that binds B7.1 and B7.2 and subverts T cell costimulation
Wang, X., Piersma, S. J., Elliott, J. I., Errico, J. M., Gainey, M. D., Yang, L., Nelson, C. A., Yokoyama, W. M. & Fremont, D. H., Oct 15 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 42, p. 21113-21119 7 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Fifty years (well, almost!) in immunology
Yokoyama, W. M., Jun 1 2019, In: Journal of Immunology. 202, 11, p. 3115-3122 8 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
First-onset herpesviral infection and lung injury in allogeneic hematopoietic cell transplantation
Zhou, X., O'Dwyer, D. N., Xia, M., Miller, H. K., Chan, P. R., Trulik, K., Chadwick, M. M., Hoffman, T. C., Bulte, C., Sekerak, K., Wilke, C. A., Patel, S. J., Yokoyama, W. M., Murray, S., Yanik, G. A. & Moore, B. B., 2019, In: American journal of respiratory and critical care medicine. 200, 1, p. 63-74 12 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis
Ardain, A., Domingo-Gonzalez, R., Das, S., Kazer, S. W., Howard, N. C., Singh, A., Ahmed, M., Nhamoyebonde, S., Rangel-Moreno, J., Ogongo, P., Lu, L., Ramsuran, D., de la Luz Garcia-Hernandez, M., K. Ulland, T., Darby, M., Park, E., Karim, F., Melocchi, L., Madansein, R. & Dullabh, K. J. & 16 others, , Jun 27 2019, In: Nature. 570, 7762, p. 528-532 5 p.Research output: Contribution to journal › Article › peer-review
Open Access156 Scopus citations -
Inducible down-regulation of MHC class I results in natural killer cell tolerance
Bern, M. D., Parikh, B. A., Yang, L., Beckman, D. L., Poursine‑Laurent, J. & Yokoyama, W. M., Jan 1 2019, In: Journal of Experimental Medicine. 216, 1, p. 99-116 18 p.Research output: Contribution to journal › Article › peer-review
Open Access51 Scopus citations -
In the absence of natural killer cell activation donor-specific antibody mediates chronic, but not acute, kidney allograft rejection
Yagisawa, T., Tanaka, T., Miyairi, S., Tanabe, K., Dvorina, N., Yokoyama, W. M., Valujskikh, A., Baldwin, W. M. & Fairchild, R. L., Feb 2019, In: Kidney International. 95, 2, p. 350-362 13 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Long-term correction of hemophilia B using adenoviral delivery of CRISPR/Cas9
Stephens, C. J., Lauron, E. J., Kashentseva, E., Lu, Z. H., Yokoyama, W. M. & Curiel, D. T., Mar 28 2019, In: Journal of Controlled Release. 298, p. 128-141 14 p.Research output: Contribution to journal › Article › peer-review
Open Access69 Scopus citations -
Publisher Correction: Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis (Nature, (2019), 570, 7762, (528-532), 10.1038/s41586-019-1276-2)
Ardain, A., Domingo-Gonzalez, R., Das, S., Kazer, S. W., Howard, N. C., Singh, A., Ahmed, M., Nhamoyebonde, S., Rangel-Moreno, J., Ogongo, P., Lu, L., Ramsuran, D., de la Luz Garcia-Hernandez, M., Ulland, T. K., Darby, M., Park, E., Karim, F., Melocchi, L., Madansein, R. & Dullabh, K. J. & 16 others, , Aug 8 2019, In: Nature. 572, 7768, p. E10Research output: Contribution to journal › Comment/debate
Open Access -
Toxoplasma gondii effector TgIST blocks type I interferon signaling to promote infection
Matta, S. K., Olias, P., Huang, Z., Wang, Q., Park, E., Yokoyama, W. M. & Sibley, L. D., Aug 27 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 35, p. 17480-17491 12 p.Research output: Contribution to journal › Article › peer-review
Open Access52 Scopus citations -
Toxoplasma gondii infection drives conversion of NK cells into ILC1-like cells
Park, E., Patel, S., Wang, Q., Andhey, P., Zaitsev, K., Porter, S., Hershey, M., Bern, M., Plougastel-Douglas, B., Collins, P., Colonna, M., Murphy, K. M., Oltz, E., Artyomov, M., Sibley, L. D. & Yokoyama, W. M., Aug 2019, In: eLife. 8, e47605.Research output: Contribution to journal › Article › peer-review
Open Access88 Scopus citations -
Uterine natural killer cells
Sojka, D. K., Yang, L. & Yokoyama, W. M., 2019, In: Frontiers in immunology. 10, MAY, 960.Research output: Contribution to journal › Review article › peer-review
Open Access119 Scopus citations -
Viral MHCI inhibition evades tissue-resident memory T cell formation and responses
Lauron, E. J., Yang, L., Harvey, I. B., Sojka, D. K., Williams, G. D., Paley, M. A., Bern, M. D., Park, E., Victorino, F., Boon, A. C. M. & Yokoyama, W. M., Jan 1 2019, In: Journal of Experimental Medicine. 216, 1, p. 117-132 16 p.Research output: Contribution to journal › Comment/debate
Open Access13 Scopus citations -
ZBTB32 restrains antibody responses to murine cytomegalovirus infections, but not other repetitive challenges
Jash, A., Zhou, Y. W., Gerardo, D. K., Ripperger, T. J., Parikh, B. A., Piersma, S., Jamwal, D. R., Kiela, P. R., Boon, A. C. M., Yokoyama, W. M., Hsieh, C. S. & Bhattacharya, D., Dec 1 2019, In: Scientific reports. 9, 1, 15257.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
2018
A herpesvirus encoded Qa-1 mimic inhibits natural killer cell cytotoxicity through CD94/NKG2A receptor engagement
Wang, X., Piersma, S. J., Nelson, C. A., Dai, Y. N., Christensen, T., Lazear, E., Yang, L., Sluijter, M., van Hall, T., Hansen, T. H., Yokoyama, W. M. & Fremont, D. H., Dec 1 2018, In: eLife. 7, e38667.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Comment on: Evidence of innate lymphoid cell redundancy in humans
Orange, J. S., Mace, E. M., French, A. R., Yokoyama, W. M., Fehniger, T. A. & Cooper, M. A., Aug 1 2018, In: Nature immunology. 19, 8, p. 788-789 2 p.Research output: Contribution to journal › Letter › peer-review
Open Access9 Scopus citations -
Cross-priming induces immunodomination in the presence of viral MHC class I inhibition
Lauron, E. J., Yang, L., Elliott, J. I., Gainey, M. D., Fremont, D. H. & Yokoyama, W. M., Feb 2018, In: PLoS pathogens. 14, 2, e1006883.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Cutting edge: Local proliferation of uterine tissue-resident NK cells during decidualization in mice
Sojka, D. K., Yang, L., Plougastel-Douglas, B., Higuchi, D. A., Anne Croy, B. & Yokoyama, W. M., Nov 1 2018, In: Journal of Immunology. 201, 9, p. 2551-2556 6 p.Research output: Contribution to journal › Article › peer-review
Open Access68 Scopus citations -
Uterine natural killer cells: To protect and to nurture
Sojka, D. K., Yang, L. & Yokoyama, W. M., Dec 1 2018, In: Birth Defects Research. 110, 20, p. 1531-1538 8 p.Research output: Contribution to journal › Review article › peer-review
Open Access29 Scopus citations -
WDFY4 is required for cross-presentation in response to viral and tumor antigens
Theisen, D. J., Davidson, J. T., Briseño, C. G., Gargaro, M., Lauron, E. J., Wang, Q., Desai, P., Durai, V., Bagadia, P., Brickner, J. R., Beatty, W. L., Virgin, H. W., Gillanders, W. E., Mosammaparast, N., Diamond, M. S., Sibley, L. D., Yokoyama, W., Schreiber, R. D., Murphy, T. L. & Murphy, K. M., Nov 9 2018, In: Science. 362, 6415, p. 694-699 6 p.Research output: Contribution to journal › Article › peer-review
Open Access235 Scopus citations -
2017
A murine herpesvirus closely related to ubiquitous human herpesviruses causes T-cell depletion
Patel, S. J., Zhao, G., Penna, V. R., Park, E., Lauron, E. J., Harvey, I. B., Beatty, W. L., Plougastel-Douglas, B., Poursine-Laurent, J., Fremont, D. H., Wang, D. & Yokoyama, W. M., May 1 2017, In: Journal of virology. 91, 9, e02463-16.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations