Wayne Yokoyama

Sam and Audrey Loew Levin Professor of Medicine, Professor of Pathology and Immunology

  • 23419 Citations
1973 …2020

Research output per year

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Personal profile

Research interests

Our laboratory is interested in basic mechanisms of innate immunity, and the immune response to viruses. We have a particular interest in the receptors expressed by natural killer cells, and the ligands for these receptors, as well as immune evasion strategies employed by viruses. My clinical interests are in rheumatology, especially the etiology and pathogenesis of rheumatoid arthritis.

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Research Output

Blood natural killer cell deficiency reveals an immunotherapy strategy for atopic dermatitis

Mack, M. R., Brestoff, J. R., Berrien-Elliott, M. M., Trier, A. M., Yang, T. L. B., McCullen, M., Collins, P. L., Niu, H., Bodet, N. D., Wagner, J. A., Park, E., Xu, A. Z., Wang, F., Chibnall, R., Council, M. L., Heffington, C., Kreisel, F., Margolis, D. J., Sheinbein, D., Lovato, P. & 7 others, Vivier, E., Cella, M., Colonna, M., Yokoyama, W. M., Oltz, G., Fehniger, T. A. & Kim, B. S., Feb 26 2020, In : Science translational medicine. 12, 532, aay1005.

Research output: Contribution to journalArticle

  • 7 Scopus citations

    cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity

    Ferris, S. T., Durai, V., Wu, R., Theisen, D. J., Ward, J. P., Bern, M. D., Davidson, J. T., Bagadia, P., Liu, T., Briseño, C. G., Li, L., Gillanders, W., Wu, G. F., Yokoyama, W. M., Murphy, T. L., Schreiber, R. D. & Murphy, K. M., Aug 27 2020, In : Nature. 584, 7822, p. 624-629 6 p.

    Research output: Contribution to journalArticle

  • Control of Viral Infection by Natural Killer Cell Inhibitory Receptors

    Parikh, B., Bern, M. D., Piersma, S., Yang, L., Beckman, D. L., Poursine-Laurent, J., Plougastel-Douglas, B. & Yokoyama, W. M., Jul 28 2020, In : Cell Reports. 32, 4, 107969.

    Research output: Contribution to journalArticle

    Open Access
  • T cell response kinetics determines neuroinfection outcomes during murine HSV infection

    Lee, A. G., Scott, J. M., Fabbrizi, M. R., Jiang, X., Sojka, D. K., Miller, M. J., Baldridge, M. T., Yokoyama, W. M. & Shin, H., Mar 12 2020, In : JCI Insight. 5, 5, e134258.

    Research output: Contribution to journalArticle

    Open Access
  • Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through STING

    Piersma, S., Poursine-Laurent, J., Yang, L., Barber, G. N., Parikh, B. & Yokoyama, W. M., Jul 29 2020, In : eLife. 9

    Research output: Contribution to journalArticle

    Open Access