Research output per year
Research output per year
Personal profile
Research interests
I am interested in the molecular mechanisms of anesthetic and lipid modulation of neural receptors and ion channels.
Clinical interests
Coronary artery bypass grafting, prosthetic valve repair/replacement, heart transplant, lung transplant.
Available to Mentor:
- PhD/MSTP Students
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel
Dalal, V., Arcario, M. J., Petroff, J. T., Tan, B. K., Dietzen, N. M., Rau, M. J., Fitzpatrick, J. A. J., Brannigan, G. & Cheng, W. W. L., Dec 2024, In: Nature communications. 15, 1, 25.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1
Schmidpeter, P. A. M., Petroff, J. T., Khajoueinejad, L., Wague, A., Frankfater, C., Cheng, W. W. L., Nimigean, C. M. & Riegelhaupt, P. M., Dec 2023, In: Nature communications. 14, 1, 1077.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Druggable Lipid Binding Sites in Pentameric Ligand-Gated Ion Channels and Transient Receptor Potential Channels
Cheng, W. W. L., Arcario, M. J. & Petroff, J. T., Jan 4 2022, In: Frontiers in Physiology. 12, 798102.Research output: Contribution to journal › Review article › peer-review
Open Access15 Scopus citations -
Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation
Petroff, J. T., Dietzen, N. M., Santiago-McRae, E., Deng, B., Washington, M. S., Chen, L. J., Trent Moreland, K., Deng, Z., Rau, M., Fitzpatrick, J. A. J., Yuan, P., Joseph, T. T., Hénin, J., Brannigan, G. & Cheng, W. W. L., Dec 2022, In: Nature communications. 13, 1, 7017.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Polyunsaturated fatty acids inhibit a pentameric ligand-gated ion channel through one of two binding sites
Dietzen, N. M., Arcario, M. J., Chen, L. J., Petroff, J. T., Moreland, K. T., Krishnan, K., Brannigan, G., Covey, D. F. & Cheng, W. W. L., Jan 2022, In: eLife. 11, e74306.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations