Wade Self

809

Citations

Research activity per year

Research interests

I wish to understand the molecular and cellular processes that lead to age-related neurodegeneration, and translate these findings into novel experimental therapeutics for disease modification and prevention.

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10 Article
5 Review article
1 Chapter
1 Comment/debate

Short-chain fatty acids are a key mediator of gut microbial regulation of T cell trafficking and differentiation after traumatic brain injury
Celorrio, M., Shumilov, K., Ni, A., Ayerra, L., Self, W. K., de Francisca, N. L. V., Rodgers, R., Schriefer, L. A., Garcia, B., Aymerich, M. S., Layden, B. T., Egervari, G., Baldridge, M. T. & Friess, S. H., Oct 2025, In: Experimental Neurology. 392, 115349.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Thwarting amyloidosis: IL-17 as a disease modifier along the gut/brain axis
Self, W. K. & Holtzman, D. M., Jul 1 2025, In: Journal of Clinical Investigation. 135, 13, e194443.
Research output: Contribution to journal › Review article › peer-review

Open Access
An emerging role for the gut microbiome in tauopathy
Zhu, Y., Self, W. K. & Holtzman, D. M., Oct 2024, In: Neurotherapeutics. 21, 6, e00423.
Research output: Contribution to journal › Review article › peer-review

Open Access
5 Scopus citations
Can the gut microbiome inform the effects of omega-3 fatty acid supplementation trials on cognition?
Kerman, B. E., Self, W. & Yassine, H. N., Mar 1 2024, In: Current opinion in clinical nutrition and metabolic care. 27, 2, p. 116-124 9 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
11 Scopus citations
Correction to: The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration (Nature Communications, (2022), 13, 1, (6901), 10.1038/s41467-022-34620-y)
Opie-Martin, S., Iacoangeli, A., Topp, S. D., Abel, O., Mayl, K., Mehta, P. R., Shatunov, A., Fogh, I., Bowles, H., Limbachiya, N., Spargo, T. P., Al-Khleifat, A., Williams, K. L., Jockel-Balsarotti, J., Bali, T., Self, W., Henden, L., Nicholson, G. A., Ticozzi, N. & McKenna-Yasek, D. & 29 others, Tang, L., Shaw, P. J., Chio, A., Ludolph, A., Weishaupt, J. H., Landers, J. E., Glass, J. D., Mora, J. S., Robberecht, W., Damme, P. V., McLaughlin, R., Hardiman, O., van den Berg, L., Veldink, J. H., Corcia, P., Stevic, Z., Siddique, N., Silani, V., Blair, I. P., Fan, D. S., Esselin, F., de la Cruz, E., Camu, W., Basak, N. A., Siddique, T., Miller, T., Brown, R. H., Al-Chalabi, A. & Shaw, C. E., Dec 2024, In: Nature communications. 15, 1, 5560.
Research output: Contribution to journal › Comment/debate

Open Access

Wade Self

Personal profile

Research interests

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Collaborations and top research areas from the last five years

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Short-chain fatty acids are a key mediator of gut microbial regulation of T cell trafficking and differentiation after traumatic brain injury

Thwarting amyloidosis: IL-17 as a disease modifier along the gut/brain axis

An emerging role for the gut microbiome in tauopathy

Can the gut microbiome inform the effects of omega-3 fatty acid supplementation trials on cognition?

Correction to: The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration (Nature Communications, (2022), 13, 1, (6901), 10.1038/s41467-022-34620-y)

Wade Self

Personal profile

Research interests

Fingerprint

Collaborations and top research areas from the last five years

Research output

Short-chain fatty acids are a key mediator of gut microbial regulation of T cell trafficking and differentiation after traumatic brain injury

Thwarting amyloidosis: IL-17 as a disease modifier along the gut/brain axis

An emerging role for the gut microbiome in tauopathy

Can the gut microbiome inform the effects of omega-3 fatty acid supplementation trials on cognition?

Correction to: The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration (Nature Communications, (2022), 13, 1, (6901), 10.1038/s41467-022-34620-y)