Vladimir Kefalov

Bernard Becker and Janet R Becker Distinguished Professorship in Ophthalmology, Professor of Neuroscience

    • 1985 Citations
    19992020

    Research output per year

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    Personal profile

    Research interests

    Our lab is interested in the mechanisms that determine the functional properties of mammalian rod and cone photoreceptors. We use a battery of tools, from single-cell and isolated retina recordings, to live electroretinogram and behavior experiments with wild type and genetically modified mice. While the emphasis of our studies is on our daytime photoreceptors, the cones, we are also investigating some aspects of rod phototransduction.

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    Research Output

    Light deprivation reduces the severity of experimental diabetic retinopathy

    Thebeau, C., Zhang, S., Kolesnikov, A. V., Kefalov, V. J., Semenkovich, C. F. & Rajagopal, R., Apr 2020, In : Neurobiology of Disease. 137, 104754.

    Research output: Contribution to journalArticle

    Open Access
  • 4 Scopus citations

    Mislocalization of cone nuclei impairs cone function in mice

    Xue, Y., Razafsky, D., Hodzic, D. & Kefalov, V. J., Aug 1 2020, In : FASEB Journal. 34, 8, p. 10242-10249 8 p.

    Research output: Contribution to journalArticle

    Open Access
  • Phosphorylation at Serine 21 in G protein-coupled receptor kinase 1 (GRK1) is required for normal kinetics of dark adaption in rod but not cone photoreceptors

    Kolesnikov, A. V., Chrispell, J. D., Osawa, S., Kefalov, V. J. & Weiss, E. R., Feb 1 2020, In : FASEB Journal. 34, 2, p. 2677-2690 14 p.

    Research output: Contribution to journalArticle

    Open Access
  • Thyroid hormone receptors mediate two distinct mechanisms of long-wavelength vision

    Volkov, L. I., Kim-Han, J. S., Saunders, L. M., Poria, D., Hughes, A. E. O., Kefalov, V. J., Parichy, D. M. & Corbo, J. C., Jun 30 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 26, p. 15262-15269 8 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    A mixture of U.S. food and drug administration-approved monoaminergic drugs protects the retina from light Damage in diverse models of night blindness

    Leinonen, H., Choi, E. H., Gardella, A., Kefalov, V. J. & Palczewski, K., Apr 2019, In : Investigative Ophthalmology and Visual Science. 60, 5, p. 1442-1453 12 p.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations