Virginia Buckles

2025

Integrative multiomics reveals common endotypes across PSEN1, PSEN2, and APP mutations in familial Alzheimer’s disease

Dominantly Inherited Alzheimer Network (DIAN), Dec 2025, In: Alzheimer's Research and Therapy. 17, 1, 5.

Research output: Contribution to journal › Article › peer-review

Open Access

2024

Generation of a gene-corrected human isogenic iPSC line from an Alzheimer's disease iPSC line carrying the PSEN1 H163R mutation

Dominantly Inherited Alzheimer Network (DIAN), Hernández, D., Morgan Schlicht, S., Elli Clarke, J., Daniszewski, M., Karch, C. M., Adams, S., Allegri, R., Araki, A., Barthelemy, N., Bateman, R., Bechara, J., Benzinger, T., Berman, S., Bodge, C., Brandon, S., (Bill) Brooks, W., Brosch, J., Buck, J. & Buckles, V. & 123 others, Carter, K., Cash, L., Chen, C., Chhatwal, J., Chrem Mendez, P., Chua, J., Chui, H., Courtney, L., Cruchaga, C., Day, G., DeLaCruz, C., Denner, D., Diffenbacher, A., Dincer, A., Donahue, T., Douglas, J., Duong, D., Egido, N., Esposito, B., Fagan, A., Farlow, M., Feldman, B., Fitzpatrick, C., Flores, S., Fox, N., Franklin, E., Friedrichsen, N., Fujii, H., Gardener, S., Ghetti, B., Goate, A., Goldberg, S., Goldman, J., Gonzalez, A., Gordon, B., Gr¨aber-Sultan, S., Graff-Radford, N., Graham, M., Gray, J., Gremminger, E., Grilo, M., Groves, A., Haass, C., H¨asler, L., Hassenstab, J., Hellm, C., Herries, E., Hoechst-Swisher, L., Hofmann, A., Holtzman, D., Hornbeck, R., Igor, Y., Ihara, R., Ikeuchi, T., Ikonomovic, S., Ishii, K., Jack, C., Jerome, G., Johnson, E., Jucker, M., Karch, C., K¨aser, S., Kasuga, K., Keefe, S., Klunk, W., Koeppe, R., Koudelis, D., Kuder-Buletta, E., Laske, C., Levey, A., Levin, J., Li, Y., Lopez, O., Marsh, J., Martins, R., Scott Mason, N., Masters, C., Mawuenyega, K., McCullough, A., McDade, E., Mejia, A., Morenas-Rodriguez, E., Morris, J., Mountz, J., Mummery, C., Nadkarni, N., Nagamatsu, A., Neimeyer, K., Niimi, Y., Noble, J., Norton, J., Nuscher, B., Obermüller, U., O'Connor, A., Patira, R., Perrin, R., Ping, L., Preische, O., Renton, A., Ringman, J., Salloway, S., Schofield, P., Senda, M., Seyfried, N. T., Shady, K., Shimada, H., Sigurdson, W., Smith, J., Smith, L., Snitz, B., Sohrabi, H., Stephens, S., Taddei, K., Thompson, S., V¨oglein, J., Wang, P., Wang, Q., Weamer, E., Xiong, C., Xu, J., Xu, X., Goate, A. M. & Pébay, A., Sep 2024, In: Stem Cell Research. 79, 103495.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

The role of the Alzheimer's Disease Neuroimaging Initiative in establishing the Dominantly Inherited Alzheimer Network

Morris, J. C. & Buckles, V. D., Aug 2024, In: Alzheimer's and Dementia. 20, 8, p. 5789-5791 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Brain network decoupling with increased serum neurofilament and reduced cognitive function in Alzheimer’s disease

Dominantly Inherited Alzheimer Network, Wheelock, M. D., Strain, J. F., Mansfield, P., Tu, J. C., Tanenbaum, A., Preische, O., Chhatwal, J. P., Cash, D. M., Cruchaga, C., Fagan, A. M., Fox, N. C., Graff-Radford, N. R., Hassenstab, J., Jack, C. R., Karch, C. M., Levin, J., McDade, E. M., Perrin, R. J. & Schofield, P. R. & 147 others, Xiong, C., Morris, J. C., Bateman, R. J., Jucker, M., Benzinger, T. L. S., Ances, B. M., Eggebrecht, A. T., Gordon, B. A., Adams, S., Allegri, R., Araki, A., Barthelemy, N., Bateman, R., Bechara, J., Benzinger, T., Berman, S., Bodge, C., Brandon, S., Brooks, W., Brosch, J., Buck, J., Buckles, V., Carter, K., Cash, D., Cash, L., Chen, C., Chhatwal, J., Chrem, P., Chua, J., Chui, H., Cruchaga, C., Day, G. S., De La Cruz, C., Denner, D., Diffenbacher, A., Dincer, A., Donahue, T., Douglas, J., Duong, D., Egido, N., Esposito, B., Fagan, A., Farlow, M., Feldman, B., Fitzpatrick, C., Flores, S., Fox, N., Franklin, E., Friedrichsen, N., Fujii, H., Gardener, S., Ghetti, B., Goate, A., Goldberg, S., Goldman, J., Gonzalez, A., Gordon, B., Gräber-Sultan, S., Graff-Radford, N., Graham, M., Gray, J., Gremminger, E., Grilo, M., Groves, A., Haass, C., Häsler, L., Hassenstab, J., Hellm, C., Herries, E., Hoechst-Swisher, L., Hofmann, A., Holtzman, D., Hornbeck, R., Igor, Y., Ihara, R., Ikeuchi, T., Ikonomovic, S., Ishii, K., Jack, C., Jerome, G., Johnson, E., Jucker, M., Karch, C., Käser, S., Kasuga, K., Keefe, S., Klunk, W., Koeppe, R., Koudelis, D., Kuder-Buletta, E., Laske, C., Lee, J. H., Levey, A., Levin, J., Li, Y., Lopez, O., Marsh, J., Martinez, R., Martins, R., Mason, N. S., Masters, C., Mawuenyega, K., McCullough, A., McDade, E., Mejia, A., Morenas-Rodriguez, E., Mori, H., Morris, J., Mountz, J., Mummery, C., Nadkami, N., Nagamatsu, A., Neimeyer, K., Niimi, Y., Noble, J., Norton, J., Nuscher, B., O’Connor, A., Obermüller, U., Patira, R., Perrin, R., Ping, L., Preische, O., Renton, A., Ringman, J., Salloway, S., Sanchez-Valle, R., Schofield, P., Senda, M., Seyfried, N., Shady, K., Shimada, H., Sigurdson, W., Smith, J., Smith, L., Snitz, B., Sohrabi, H., Stephens, S., Taddei, K., Thompson, S., Vöglein, J., Wang, P., Wang, Q., Weamer, E., Xiong, C., Xu, J. & Xu, X., Jul 1 2023, In: Brain. 146, 7, p. 2928-2943 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study

Alzheimer's Biomarker Consortium-Down Syndrome, Dominantly Inherited Alzheimer Network, Boerwinkle, A. H., Gordon, B. A., Wisch, J., Flores, S., Henson, R. L., Butt, O. H., McKay, N., Chen, C. D., Benzinger, T. L. S., Fagan, A. M., Cruchaga, C., Perrin, R. J., Xiong, C., Hassenstab, J., McDade, E., Bateman, R. J., Ances, B. M. & Barthelemy, N. & 8 others, Buckles, V., Day, G., Joseph-Mathurin, N., Holtzman, D., Karch, C., Li, Y., Wang, Q. & Xu, J., Jan 2023, In: The Lancet Neurology. 22, 1, p. 55-65 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

Cross-sectional and longitudinal comparisons of biomarkers and cognition among asymptomatic middle-aged individuals with a parental history of either autosomal dominant or late-onset Alzheimer's disease

and Dominantly Inherited Alzheimer Network (DIAN), Xiong, C., McCue, L. M., Buckles, V., Grant, E., Agboola, F., Coble, D., Bateman, R. J., Fagan, A. M., Benzinger, T. L. S., Hassenstab, J., Schindler, S. E., McDade, E., Moulder, K., Gordon, B. A., Cruchaga, C., Day, G. S., Ikeuchi, T., Suzuki, K. & Allegri, R. F. & 3 others, Vöglein, J., Levin, J. & Morris, J. C., Jul 2023, In: Alzheimer's and Dementia. 19, 7, p. 2923-2932 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Pattern and implications of neurological examination findings in autosomal dominant Alzheimer disease

for the Dominantly Inherited Alzheimer Network, Feb 2023, In: Alzheimer's and Dementia. 19, 2, p. 632-645 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

2022

Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology

Morris, J. C., Weiner, M., Xiong, C., Beckett, L., Coble, D., Saito, N., Aisen, P. S., Allegri, R., Benzinger, T. L. S., Berman, S. B., Cairns, N. J., Carrillo, M. C., Chui, H. C., Chhatwal, J. P., Cruchaga, C., Fagan, A. M., Farlow, M., Fox, N. C., Ghetti, B. & Goate, A. M. & 27 others, Gordon, B. A., Graff-Radford, N., Day, G., Hassenstab, J., Ikeuchi, T., Jack, C. R., Jagust, W. J., Jucker, M., Levin, J., Massoumzadeh, P., Masters, C. L., Martins, R., McDade, E., Mori, H., Noble, J. M., Petersen, R. C., Ringman, J. M., Salloway, S., Saykin, A. J., Schofield, P. R., Shaw, L. M., Toga, A. W., Trojanowski, J. Q., Vöglein, J., Weninger, S., Bateman, R. J. & Buckles, V., Oct 1 2022, In: Brain. 145, 10, p. 3594-3607 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Different rates of cognitive decline in autosomal dominant and late-onset Alzheimer disease

for the Dominantly Inherited Alzheimer's Network, Oct 2022, In: Alzheimer's and Dementia. 18, 10, p. 1754-1764 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid

Dominantly Inherited Alzheimer Network, Nov 17 2022, In: Nature. 611, 7936, p. 585-593 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

147 Scopus citations

Predicting brain age from functional connectivity in symptomatic and preclinical Alzheimer disease

for the Dominantly Inherited Alzheimer Network, Millar, P. R., Luckett, P. H., Gordon, B. A., Benzinger, T. L. S., Schindler, S. E., Fagan, A. M., Cruchaga, C., Bateman, R. J., Morris, J. C., Ances, B. M., Barthelemy, N., Bateman, R., Day, G. S., Joseph-Mathurin, N., Hassenstab, J., Holtzman, D., Karch, C., Li, Y. & McDade, E. & 5 others, Morris, J., Perrin, R., Wang, Q., Xiong, C. & Xu, J., Aug 1 2022, In: NeuroImage. 256, 119228.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study

Dominantly Inherited Alzheimer Network, Apr 2022, In: The Lancet Neurology. 21, 4, p. 329-341 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

112 Scopus citations

2021

Amyloid and Tau Pathology Associations With Personality Traits, Neuropsychiatric Symptoms, and Cognitive Lifestyle in the Preclinical Phases of Sporadic and Autosomal Dominant Alzheimer's Disease

Dominantly Inherited Alzheimer Network (DIAN) & PREVENT-AD Research Group, Apr 15 2021, In: Biological Psychiatry. 89, 8, p. 776-785 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

44 Scopus citations

Predicting Symptom Onset in Sporadic Alzheimer Disease With Amyloid PET

Schindler, S., Li, Y., Buckles, V., Gordon, B., Benzinger, T. L. S., Wang, G., Coble, D., Klunk, W. E., Fagan, A. M., Holtzman, D. M., Bateman, R. J., Morris, J. & Xiong, C., Nov 2 2021, In: Neurology. 97, 18, p. E1823-E1834

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

2020

A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease

the Dominantly Inherited Alzheimer Network, Mar 1 2020, In: Nature medicine. 26, 3, p. 398-407 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

432 Scopus citations

Awareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN)

Dominantly Inherited Alzheimer Network, Jan 1 2020, In: Alzheimer's and Dementia. 16, 1, p. 219-228 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Single-subject grey matter network trajectories over the disease course of autosomal dominant Alzheimer's disease

Vermunt, L., Dicks, E., Wang, G., Dincer, A., Flores, S., Keefe, S. J., Berman, S. B., Cash, D. M., Chhatwal, J. P., Cruchaga, C., Fox, N. C., Ghetti, B., Graff-Radford, N. R., Hassenstab, J., Karch, C. M., Laske, C., Levin, J., Masters, C. L., McDade, E. & Mori, H. & 92 others, Morris, J. C., Noble, J. M., Perrin, R. J., Schofield, P. R., Xiong, C., Scheltens, P., Visser, P. J., Bateman, R. J., Benzinger, T. L. S., Tijms, B. M., Gordon, B. A., Allegri, R., Amtashar, F., Berman, S., Bodge, C., Brandon, S., Brooks, W., Buck, J., Buckles, V., Chea, S., Chrem, P., Chui, H., Cinco, J., Jack, C., D'Mello, M., Donahue, T., Douglas, J., Edigo, N., Erekin-Taner, N., Fagan, A., Farlow, M., Farrar, A., Feldman, H., Flynn, G., Fox, N., Franklin, E., Fujii, H., Gant, C., Gardener, S., Ghetti, B., Goate, A., Goldman, J., Gordon, B., Gray, J., Gurney, J., Hassenstab, J., Hirohara, M., Holtzman, D., Hornbeck, R., Dibari, S. H., Ikeuchi, T., Ikonomovic, S., Jerome, G., Jucker, M., Kasuga, K., Kawarabayashi, T., Klunk, W., Koeppe, R., Kuder-Buletta, E., Laske, C., Levin, J., Marcus, D., Martins, R., Mason, N. S., Maue-Dreyfus, D., McDade, E., Montoya, L., Mori, H., Nagamatsu, A., Neimeyer, K., Noble, J., Norton, J., Perrin, R., Raichle, M., Ringman, J., Roh, J. H., Schofield, P., Shimada, H., Shiroto, T., Shoji, M., Sigurdson, W., Sohrabi, H., Sparks, P., Suzuki, K., Swisher, L., Taddei, K., Wang, J., Wang, P., Weiner, M., Wolfsberger, M., Xiong, C. & Xu, X., Dec 1 2020, In: Brain Communications. 2, 2, fcaa102.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

2019

An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations

the Dominantly Inherited Alzheimer Network (DIAN), Nov 1 2019, In: Nature neuroscience. 22, 11, p. 1903-1912 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

254 Scopus citations

Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer's disease

Vöglein, J., Paumier, K., Jucker, M., Preische, O., McDade, E., Hassenstab, J., Benzinger, T. L., Noble, J. M., Berman, S. B., Graff-Radford, N. R., Ghetti, B., Farlow, M. R., Chhatwal, J., Salloway, S., Xiong, C., Karch, C. M., Cairns, N., Mori, H., Schofield, P. R. & Masters, C. L. & 16 others, Goate, A., Buckles, V., Fox, N., Rossor, M., Chrem, P., Allegri, R., Ringman, J. M., Höglinger, G., Steiner, H., Dieterich, M., Haass, C., Laske, C., Morris, J. C., Bateman, R. J., Danek, A. & Levin, J., May 1 2019, In: Brain. 142, 5, p. 1429-1440 12 p., awz050.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

Seizures as an early symptom of autosomal dominant Alzheimer's disease

Dominantly Inherited Alzheimer Network, Apr 2019, In: Neurobiology of Aging. 76, p. 18-23 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease

Dominantly Inherited Alzheimer Network, Feb 1 2019, In: Nature medicine. 25, 2, p. 277-283 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

658 Scopus citations

2018

Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease

McDade, E., Wang, G., Gordon, B. A., Hassenstab, J., Benzinger, T. L. S., Buckles, V., Fagan, A. M., Holtzman, D. M., Cairns, N. J., Goate, A. M., Marcus, D. S., Morris, J. C., Paumier, K., Xiong, C., Allegri, R., Berman, S. B., Klunk, W., Noble, J., Ringman, J. & Ghetti, B. & 12 others, Farlow, M., Sperling, R. A., Chhatwal, J., Salloway, S., Graff-Radford, N. R., Schofield, P. R., Masters, C., Rossor, M. N., Fox, N. C., Levin, J., Jucker, M. & Bateman, R. J., Oct 2 2018, In: Neurology. 91, 14, p. E1295-E1306

Research output: Contribution to journal › Article › peer-review

Open Access

226 Scopus citations

Preferential degradation of cognitive networks differentiates Alzheimer's disease from ageing

Chhatwal, J. P., Schultz, A. P., Johnson, K. A., Hedden, T., Jaimes, S., Benzinger, T. L. S., Jack, C., Ances, B. M., Ringman, J. M., Marcus, D. S., Ghetti, B., Farlow, M. R., Danek, A., Levin, J., Yakushev, I., Laske, C., Koeppe, R. A., Galasko, D. R., Xiong, C. & Masters, C. L. & 10 others, Schofield, P. R., Kinnunen, K. M., Salloway, S., Martins, R. N., McDade, E., Cairns, N. J., Buckles, V. D., Morris, J. C., Bateman, R. & Sperling, R. A., May 1 2018, In: Brain. 141, 5, p. 1486-1500 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

77 Scopus citations

Relationship between physical activity, cognition, and Alzheimer pathology in autosomal dominant Alzheimer's disease

Dominantly Inherited Alzheimer Network (DIAN), Nov 2018, In: Alzheimer's and Dementia. 14, 11, p. 1427-1437 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

63 Scopus citations

Utility of perfusion PET measures to assess neuronal injury in Alzheimer's disease

Dominantly Inherited Alzheimer Network, Jan 1 2018, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 669-677 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer’s disease

Lee, S., Zimmerman, M. E., Narkhede, A., Nasrabady, S. E., Tosto, G., Meier, I. B., Benzinger, T. L. S., Marcus, D. S., Fagan, A. M., Fox, N. C., Cairns, N. J., Holtzman, D. M., Buckles, V., Ghetti, B., McDade, E., Martins, R. N., Saykin, A. J., Masters, C. L., Ringman, J. M. & Fӧrster, S. & 12 others, Schofield, P. R., Sperling, R. A., Johnson, K. A., Chhatwal, J. P., Salloway, S., Correia, S., Jack, C. R., Weiner, M., Bateman, R. J., Morris, J. C., Mayeux, R. & Brickman, A. M., May 2018, In: PloS one. 13, 5, e0195838.

Research output: Contribution to journal › Article › peer-review

Open Access

56 Scopus citations

2017

Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer's disease

Müller, S., Preische, O., Sohrabi, H. R., Gräber, S., Jucker, M., Dietzsch, J., Ringman, J. M., Martins, R. N., McDade, E., Schofield, P. R., Ghetti, B., Rossor, M., Graff-Radford, N. R., Levin, J., Galasko, D., Quaid, K. A., Salloway, S., Xiong, C., Benzinger, T. & Buckles, V. & 5 others, Masters, C. L., Sperling, R., Bateman, R. J., Morris, J. C. & Laske, C., Dec 1 2017, In: Scientific reports. 7, 1, 1225.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

Habitual exercise levels are associated with cerebral amyloid load in presymptomatic autosomal dominant Alzheimer's disease

the Dominantly Inherited Alzheimer Network, Nov 2017, In: Alzheimer's and Dementia. 13, 11, p. 1197-1206 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

51 Scopus citations

2016

Longitudinal relationships among biomarkers for Alzheimer disease in the Adult Children Study

Xiong, C., Jasielec, M. S., Weng, H., Fagan, A. M., Benzinger, T. L. S., Head, D., Hassenstab, J., Grant, E., Sutphen, C. L., Buckles, V., Moulder, K. L. & Morris, J. C., Apr 19 2016, In: Neurology. 86, 16, p. 1499-1506 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

40 Scopus citations

Neurological manifestations of autosomal dominant familial Alzheimer's disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS)

Dominantly Inherited Alzheimer Network (DIAN), Dec 1 2016, In: The Lancet Neurology. 15, 13, p. 1317-1325 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

94 Scopus citations

White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network

Lee, S., Viqar, F., Zimmerman, M. E., Narkhede, A., Tosto, G., Benzinger, T. L. S., Marcus, D. S., Fagan, A. M., Goate, A., Fox, N. C., Cairns, N. J., Holtzman, D. M., Buckles, V., Ghetti, B., McDade, E., Martins, R. N., Saykin, A. J., Masters, C. L., Ringman, J. M. & Ryan, N. S. & 12 others, Förster, S., Laske, C., Schofield, P. R., Sperling, R. A., Salloway, S., Correia, S., Jack, C., Weiner, M., Bateman, R. J., Morris, J. C., Mayeux, R. & Brickman, A. M., Jun 1 2016, In: Annals of neurology. 79, 6, p. 929-939 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

406 Scopus citations

2015

A survey of attitudes toward clinical trials and genetic disclosure in autosomal dominant Alzheimer's disease

Dominantly Inherited Alzheimer's Network, Grill, J. D., Bateman, R. J., Buckles, V., Oliver, A., Morris, J. C., Masters, C. L., Klunk, W. E. & Ringman, J. M., Jul 22 2015, In: Alzheimer's Research and Therapy. 7, 1, 50.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Cerebrospinal fluid markers of neurodegeneration and rates of brain atrophy in early Alzheimer disease

Tarawneh, R., Head, D., Allison, S., Buckles, V., Fagan, A. M., Ladenson, J. H., Morris, J. C. & Holtzman, D. M., Jun 1 2015, In: JAMA Neurology. 72, 6, p. 656-665 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

79 Scopus citations

Diagnostic Value of Subjective Memory Complaints Assessed with a Single Item in Dominantly Inherited Alzheimer's Disease: Results of the DIAN Study

Laske, C., Sohrabi, H. R., Jasielec, M. S., Müller, S., Koehler, N. K., Gräber, S., Förster, S., Drzezga, A., Mueller-Sarnowski, F., Danek, A., Jucker, M., Bateman, R. J., Buckles, V., Saykin, A. J., Martins, R. N. & Morris, J. C., 2015, In: BioMed Research International. 2015, 828120.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Early behavioural changes in familial Alzheimer's disease in the Dominantly Inherited Alzheimer Network

Ringman, J. M., Liang, L. J., Zhou, Y., Vangala, S., Teng, E., Kremen, S., Wharton, D., Goate, A., Marcus, D. S., Farlow, M., Ghetti, B., McDade, E., Masters, C. L., Mayeux, R. P., Rossor, M., Salloway, S., Schofield, P. R., Cummings, J. L., Buckles, V. & Bateman, R. & 1 others, Morris, J. C., Apr 1 2015, In: Brain. 138, 4, p. 1036-1045 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

69 Scopus citations

Erratum: Early behavioural changes in familial Alzheimers disease in the Dominantly Inherited Alzheimer Network (Brain (2015) 138 (103645) (10.1093/brain/awv004))

Ringman, J. M., Liang, L. J., Zhou, Y., Vangala, S., Teng, E., Kremen, S., Wharton, D., Goate, A., Marcus, D. S., Farlow, M., Ghetti, B., McDade, E., Masters, C. L., Mayeux, R. P., Rossor, M., Salloway, S., Schofield, P. R., Cummings, J. L., Buckles, V. & Bateman, R. & 1 others, Morris, J. C., Dec 1 2015, In: Brain. 138, 12, p. e401

Research output: Contribution to journal › Comment/debate

Open Access

Partial volume correction in quantitative amyloid imaging

Dominantly Inherited Alzheimer Network, Feb 5 2015, In: NeuroImage. 107, p. 55-64 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

194 Scopus citations

2014

Functional connectivity in autosomal dominant and late-onset Alzheimer disease

Thomas, J. B., Brier, M. R., Bateman, R. J., Snyder, A. Z., Benzinger, T. L., Xiong, C., Raichle, M., Holtzman, D. M., Sperling, R. A., Mayeux, R., Ghetti, B., Ringman, J. M., Salloway, S., McDade, E., Rossor, M. N., Ourselin, S., Schofield, P. R., Masters, C. L., Martins, R. N. & Weiner, M. W. & 18 others, Thompson, P. M., Fox, N. C., Koeppe, R. A., Jack, C. R., Mathis, C. A., Oliver, A., Blazey, T. M., Moulder, K., Buckles, V., Hornbeck, R., Chhatwal, J., Schultz, A. P., Goate, A. M., Fagan, A. M., Cairns, N. J., Marcus, D. S., Morris, J. C. & Ances, B. M., Sep 1 2014, In: JAMA Neurology. 71, 9, p. 1111-1122 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

86 Scopus citations

Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease

Fagan, A. M., Xiong, C., Jasielec, M. S., Bateman, R. J., Goate, A. M., Benzinger, T. L. S., Ghetti, B., Martins, R. N., Masters, C. L., Mayeux, R., Ringman, J. M., Rossor, M. N., Salloway, S., Schofield, P. R., Sperling, R. A., Marcus, D., Cairns, N. J., Buckles, V. D., Ladenson, J. H. & Morris, J. C. & 1 others, Holtzman, D. M., Mar 5 2014, In: Science translational medicine. 6, 226, 226ra30.

Research output: Contribution to journal › Article › peer-review

Open Access

321 Scopus citations

2013

Clinicopathologic study of alzheimer's disease: Alzheimer mimics

Shim, Y. S., Roe, C. M., Buckles, V. D. & Morris, J. C., 2013, In: Journal of Alzheimer's Disease. 35, 4, p. 799-811 13 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

44 Scopus citations

Dominantly inherited alzheimer network: Facilitating research and clinical trials

Moulder, K. L., Snider, B. J., Mills, S. L., Buckles, V. D., Santacruz, A. M., Bateman, R. J. & Morris, J. C., 2013, In: Alzheimer's Research and Therapy. 5, 5, 48.

Research output: Contribution to journal › Review article › peer-review

Open Access

128 Scopus citations

Erratum: Preclinical trials in autosomal dominant AD: Implementation of the DIAN-TU trial (Rev. Neurol. (2013) 169 (10) (737-743))

Mills, S. M., Mallmann, J., Santacruz, A. M., Fuqua, A., Carril, M., Aisen, P. S., Althage, M. C., Belyew, S., Benzinger, T. L., Brooks, W. S., Buckles, V. D., Cairns, N. J., Clifford, D., Danek, A., Fagan, A. M., Farlow, M., Fox, N., Ghetti, B., Goate, A. M. & Heinrichs, D. & 22 others, Hornbeck, R., Jack, C., Jucker, M., Klunk, W. E., Marcus, D. S., Martins, R. N., Masters, C. M., Mayeux, R., McDade, E., Morris, J. C., Oliver, A., Ringman, J. M., Rossor, M. N., Salloway, S., Schofield, P. R., Snider, J., Snyder, P., Sperling, R. A., Stewart, C., Thomas, R. G., Xiong, C. & Bateman, R. J., Dec 2013, In: Revue Neurologique. 169, 12, p. 1018 1 p.

Research output: Contribution to journal › Comment/debate

Impaired default network functional connectivity in autosomal dominant Alzheimer disease

Chhatwal, J. P., Schultz, A. P., Johnson, K., Benzinger, T. L. S., Jack, C., Ances, B. M., Sullivan, C. A., Salloway, S. P., Ringman, J. M., Koeppe, R. A., Marcus, D. S., Thompson, P., Saykin, A. J., Correia, S., Schofield, P. R., Rowe, C. C., Fox, N. C., Brickman, A. M., Mayeux, R. & McDade, E. & 7 others, Bateman, R., Fagan, A. M., Goate, A. M., Xiong, C., Buckles, V. D., Morris, J. C. & Sperling, R. A., Aug 20 2013, In: Neurology. 81, 8, p. 736-744 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

140 Scopus citations

Preclinical Alzheimer disease and risk of falls

Stark, S. L., Roe, C. M., Grant, E. A., Hollingsworth, H., Benzinger, T. L., Fagan, A. M., Buckles, V. D. & Morris, J. C., Jul 30 2013, In: Neurology. 81, 5, p. 437-443 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

66 Scopus citations

Preclinical trials in autosomal dominant AD: Implementation of the DIAN-TU trial

Mills, S. M., Mallmann, J., Santacruz, A. M., Fuqua, A., Carril, M., Aisen, P. S., Althage, M. C., Belyew, S., Benzinger, T. L., Brooks, W. S., Buckles, V. D., Cairns, N. J., Clifford, D., Danek, A., Fagan, A. M., Farlow, M., Fox, N., Ghetti, B., Goate, A. M. & Heinrichs, D. & 22 others, Hornbeck, R., Jack, C., Jucker, M., Klunk, W. E., Marcus, D. S., Martins, R. N., Masters, C. M., Mayeux, R., McDade, E., Morris, J. C., Oliver, A., Ringman, J. M., Rossor, M. N., Salloway, S., Schofield, P. R., Snider, J., Snyder, P., Sperling, R. A., Stewart, C., Thomas, R. G., Xiong, C. & Bateman, R. J., Oct 2013, In: Revue Neurologique. 169, 10, p. 737-743 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

125 Scopus citations

Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease

Benzinger, T. L. S., Blazey, T., Jack, C. R., Koeppe, R. A., Su, Y., Xiong, C., Raichle, M. E., Snyder, A. Z., Ances, B. M., Bateman, R. J., Cairns, N. J., Fagan, A. M., Goate, A., Marcus, D. S., Aisen, P. S., Christensen, J. J., Ercole, L., Hornbeck, R. C., Farrar, A. M. & Aldea, P. & 30 others, Jasielec, M. S., Owen, C. J., Xie, X., Mayeux, R., Brickman, A., McDade, E., Klunk, W., Mathis, C. A., Ringman, J., Thompson, P. M., Ghetti, B., Saykin, A. J., Sperling, R. A., Johnson, K. A., Salloway, S., Correia, S., Schofield, P. R., Masters, C. L., Rowe, C., Villemagne, V. L., Martins, R., Ourselin, S., Rossor, M. N., Fox, N. C., Cash, D. M., Weiner, M. W., Holtzman, D. M., Buckles, V. D., Moulder, K. & Morris, J. C., Nov 19 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 47, p. E4502-E4509

Research output: Contribution to journal › Article › peer-review

Open Access

311 Scopus citations

"Will I get alzheimer disease?" When cognitively normal patients ask to be tested for alzheimer disease

Snider, B. J. & Buckles, V. D., Apr 2013, In: CONTINUUM Lifelong Learning in Neurology. 19, 2, p. 470-474 5 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

2 Scopus citations

2012

Clinical and biomarker changes in dominantly inherited Alzheimer's disease

Bateman, R. J., Xiong, C., Benzinger, T. L. S., Fagan, A. M., Goate, A., Fox, N. C., Marcus, D. S., Cairns, N. J., Xie, X., Blazey, T. M., Holtzman, D. M., Santacruz, A., Buckles, V., Oliver, A., Moulder, K., Aisen, P. S., Ghetti, B., Klunk, W. E., McDade, E. & Martins, R. N. & 8 others, Masters, C. L., Mayeux, R., Ringman, J. M., Rossor, M. N., Schofield, P. R., Sperling, R. A., Salloway, S. & Morris, J. C., Aug 30 2012, In: New England Journal of Medicine. 367, 9, p. 795-804 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3004 Scopus citations

2011

Role of family history for Alzheimer biomarker abnormalities in the adult children study

Xiong, C., Roe, C. M., Buckles, V., Fagan, A., Holtzman, D., Balota, D., Duchek, J., Storandt, M., Mintun, M., Grant, E., Snyder, A. Z., Head, D., Benzinger, T. L. S., Mettenburg, J., Csernansky, J. & Morris, J. C., Oct 2011, In: Archives of neurology. 68, 10, p. 1313-1319 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

51 Scopus citations

2009

Neuropathology of nondemented aging: Presumptive evidence for preclinical Alzheimer disease

Price, J. L., McKeel, D. W., Buckles, V. D., Roe, C. M., Xiong, C., Grundman, M., Hansen, L. A., Petersen, R. C., Parisi, J. E., Dickson, D. W., Smith, C. D., Davis, D. G., Schmitt, F. A., Markesbery, W. R., Kaye, J., Kurlan, R., Hulette, C., Kurland, B. F., Higdon, R. & Kukull, W. & 1 others, Morris, J. C., Jul 2009, In: Neurobiology of Aging. 30, 7, p. 1026-1036 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

547 Scopus citations

Virginia Buckles

Research output

Search results