Virginia Buckles

Generation of a gene-corrected human isogenic iPSC line from an Alzheimer's disease iPSC line carrying the PSEN1 H163R mutation

Dominantly Inherited Alzheimer Network (DIAN), Hernández, D., Morgan Schlicht, S., Elli Clarke, J., Daniszewski, M., Karch, C. M., Adams, S., Allegri, R., Araki, A., Barthelemy, N., Bateman, R., Bechara, J., Benzinger, T., Berman, S., Bodge, C., Brandon, S., (Bill) Brooks, W., Brosch, J., Buck, J. & Buckles, V. & 123 others, Carter, K., Cash, L., Chen, C., Chhatwal, J., Chrem Mendez, P., Chua, J., Chui, H., Courtney, L., Cruchaga, C., Day, G., DeLaCruz, C., Denner, D., Diffenbacher, A., Dincer, A., Donahue, T., Douglas, J., Duong, D., Egido, N., Esposito, B., Fagan, A., Farlow, M., Feldman, B., Fitzpatrick, C., Flores, S., Fox, N., Franklin, E., Friedrichsen, N., Fujii, H., Gardener, S., Ghetti, B., Goate, A., Goldberg, S., Goldman, J., Gonzalez, A., Gordon, B., Gr¨aber-Sultan, S., Graff-Radford, N., Graham, M., Gray, J., Gremminger, E., Grilo, M., Groves, A., Haass, C., H¨asler, L., Hassenstab, J., Hellm, C., Herries, E., Hoechst-Swisher, L., Hofmann, A., Holtzman, D., Hornbeck, R., Igor, Y., Ihara, R., Ikeuchi, T., Ikonomovic, S., Ishii, K., Jack, C., Jerome, G., Johnson, E., Jucker, M., Karch, C., K¨aser, S., Kasuga, K., Keefe, S., Klunk, W., Koeppe, R., Koudelis, D., Kuder-Buletta, E., Laske, C., Levey, A., Levin, J., Li, Y., Lopez, O., Marsh, J., Martins, R., Scott Mason, N., Masters, C., Mawuenyega, K., McCullough, A., McDade, E., Mejia, A., Morenas-Rodriguez, E., Morris, J., Mountz, J., Mummery, C., Nadkarni, N., Nagamatsu, A., Neimeyer, K., Niimi, Y., Noble, J., Norton, J., Nuscher, B., Obermüller, U., O'Connor, A., Patira, R., Perrin, R., Ping, L., Preische, O., Renton, A., Ringman, J., Salloway, S., Schofield, P., Senda, M., Seyfried, N. T., Shady, K., Shimada, H., Sigurdson, W., Smith, J., Smith, L., Snitz, B., Sohrabi, H., Stephens, S., Taddei, K., Thompson, S., V¨oglein, J., Wang, P., Wang, Q., Weamer, E., Xiong, C., Xu, J., Xu, X., Goate, A. M. & Pébay, A., Sep 2024, In: Stem Cell Research. 79, 103495.

Research output: Contribution to journal › Article › peer-review

Open Access

The role of the Alzheimer's Disease Neuroimaging Initiative in establishing the Dominantly Inherited Alzheimer Network

Morris, J. C. & Buckles, V. D., Aug 2024, In: Alzheimer's and Dementia. 20, 8, p. 5789-5791 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Brain network decoupling with increased serum neurofilament and reduced cognitive function in Alzheimer’s disease

Dominantly Inherited Alzheimer Network, Wheelock, M. D., Strain, J. F., Mansfield, P., Tu, J. C., Tanenbaum, A., Preische, O., Chhatwal, J. P., Cash, D. M., Cruchaga, C., Fagan, A. M., Fox, N. C., Graff-Radford, N. R., Hassenstab, J., Jack, C. R., Karch, C. M., Levin, J., McDade, E. M., Perrin, R. J. & Schofield, P. R. & 147 others, Xiong, C., Morris, J. C., Bateman, R. J., Jucker, M., Benzinger, T. L. S., Ances, B. M., Eggebrecht, A. T., Gordon, B. A., Adams, S., Allegri, R., Araki, A., Barthelemy, N., Bateman, R., Bechara, J., Benzinger, T., Berman, S., Bodge, C., Brandon, S., Brooks, W., Brosch, J., Buck, J., Buckles, V., Carter, K., Cash, D., Cash, L., Chen, C., Chhatwal, J., Chrem, P., Chua, J., Chui, H., Cruchaga, C., Day, G. S., De La Cruz, C., Denner, D., Diffenbacher, A., Dincer, A., Donahue, T., Douglas, J., Duong, D., Egido, N., Esposito, B., Fagan, A., Farlow, M., Feldman, B., Fitzpatrick, C., Flores, S., Fox, N., Franklin, E., Friedrichsen, N., Fujii, H., Gardener, S., Ghetti, B., Goate, A., Goldberg, S., Goldman, J., Gonzalez, A., Gordon, B., Gräber-Sultan, S., Graff-Radford, N., Graham, M., Gray, J., Gremminger, E., Grilo, M., Groves, A., Haass, C., Häsler, L., Hassenstab, J., Hellm, C., Herries, E., Hoechst-Swisher, L., Hofmann, A., Holtzman, D., Hornbeck, R., Igor, Y., Ihara, R., Ikeuchi, T., Ikonomovic, S., Ishii, K., Jack, C., Jerome, G., Johnson, E., Jucker, M., Karch, C., Käser, S., Kasuga, K., Keefe, S., Klunk, W., Koeppe, R., Koudelis, D., Kuder-Buletta, E., Laske, C., Lee, J. H., Levey, A., Levin, J., Li, Y., Lopez, O., Marsh, J., Martinez, R., Martins, R., Mason, N. S., Masters, C., Mawuenyega, K., McCullough, A., McDade, E., Mejia, A., Morenas-Rodriguez, E., Mori, H., Morris, J., Mountz, J., Mummery, C., Nadkami, N., Nagamatsu, A., Neimeyer, K., Niimi, Y., Noble, J., Norton, J., Nuscher, B., O’Connor, A., Obermüller, U., Patira, R., Perrin, R., Ping, L., Preische, O., Renton, A., Ringman, J., Salloway, S., Sanchez-Valle, R., Schofield, P., Senda, M., Seyfried, N., Shady, K., Shimada, H., Sigurdson, W., Smith, J., Smith, L., Snitz, B., Sohrabi, H., Stephens, S., Taddei, K., Thompson, S., Vöglein, J., Wang, P., Wang, Q., Weamer, E., Xiong, C., Xu, J. & Xu, X., Jul 1 2023, In: Brain. 146, 7, p. 2928-2943 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study

Alzheimer's Biomarker Consortium-Down Syndrome, Dominantly Inherited Alzheimer Network, Boerwinkle, A. H., Gordon, B. A., Wisch, J., Flores, S., Henson, R. L., Butt, O. H., McKay, N., Chen, C. D., Benzinger, T. L. S., Fagan, A. M., Cruchaga, C., Perrin, R. J., Xiong, C., Hassenstab, J., McDade, E., Bateman, R. J., Ances, B. M. & Barthelemy, N. & 8 others, Buckles, V., Day, G., Joseph-Mathurin, N., Holtzman, D., Karch, C., Li, Y., Wang, Q. & Xu, J., Jan 2023, In: The Lancet Neurology. 22, 1, p. 55-65 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

Cross-sectional and longitudinal comparisons of biomarkers and cognition among asymptomatic middle-aged individuals with a parental history of either autosomal dominant or late-onset Alzheimer's disease

and Dominantly Inherited Alzheimer Network (DIAN), Xiong, C., McCue, L. M., Buckles, V., Grant, E., Agboola, F., Coble, D., Bateman, R. J., Fagan, A. M., Benzinger, T. L. S., Hassenstab, J., Schindler, S. E., McDade, E., Moulder, K., Gordon, B. A., Cruchaga, C., Day, G. S., Ikeuchi, T., Suzuki, K. & Allegri, R. F. & 3 others, Vöglein, J., Levin, J. & Morris, J. C., Jul 2023, In: Alzheimer's and Dementia. 19, 7, p. 2923-2932 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Virginia Buckles

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Generation of a gene-corrected human isogenic iPSC line from an Alzheimer's disease iPSC line carrying the PSEN1 H163R mutation

The role of the Alzheimer's Disease Neuroimaging Initiative in establishing the Dominantly Inherited Alzheimer Network

Brain network decoupling with increased serum neurofilament and reduced cognitive function in Alzheimer’s disease

Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study

Cross-sectional and longitudinal comparisons of biomarkers and cognition among asymptomatic middle-aged individuals with a parental history of either autosomal dominant or late-onset Alzheimer's disease