Research Output per year
Research Output per year
Personal profile
Research interests
My research interests focus on the impact of CD36 deficiency on inflammation and lipid trafficking. CD36 deletion disrupts immune cell trafficking to lymph nodes and results in chronic inflammation driven by neutrophils. Humans with partial CD36 deficiency, which associates with abnormal chylomicron clearance, have more activated neutrophils in the circulation, suggesting subclinical inflammation. CD36 deletion affects the lymphatic system, rerouting more of intestinal chylomicrons to the liver, promoting hepatic steatosis and early signs of fibrosis.
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Research Output
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Decreased adipose tissue oxygenation associates with insulin resistance in individuals with obesity
Cifarelli, V., Beeman, S. C., Smith, G. I., Yoshino, J., Morozov, D., Beals, J. W., Kayser, B. D., Watrous, J. D., Jain, M., Patterson, B. W. & Klein, S., Dec 1 2020, In: Journal of Clinical Investigation. 130, 12, p. 6688-6699 12 p.Research output: Contribution to journal › Article › peer-review
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The Intestinal Lymphatic System: Functions and Metabolic Implications
Cifarelli, V. & Eichmann, A., 2019, In: CMGH. 7, 3, p. 503-513 11 p.Research output: Contribution to journal › Review article › peer-review
Open Access19 Scopus citations -
Enterocyte Fatty Acid Handling Proteins and Chylomicron Formation
Cifarelli, V. & Abumrad, N. A., Mar 28 2018, Physiology of the Gastrointestinal Tract: Sixth Edition. Elsevier Inc., Vol. 2-2. p. 1087-1107 21 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
1 Scopus citations -
Intestinal CD36 and other key proteins of lipid utilization: Role in absorption and gut homeostasis
Cifarelli, V. & Abumrad, N. A., Apr 2018, In: Comprehensive Physiology. 8, 2, p. 493-507 15 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Normalized neutral lipid quantitation by flow cytometry
Wolins, N. E., DeHaan, K. N., Cifarelli, V. & Stoeckman, A. K., 2018, In: Journal of lipid research. 59, 7, p. 1294-1300 7 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations