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Personal profile

Research interests

I am a patient-oriented researcher with interests in chronic renal failure, pediatric kidney transplantation and post-transplant infections. I perform epidemiological analyses of very large national databases to elucidate risk factors for events and the outcomes after events, typically infectious events. These large databases include UNOS, USRDS, NAPRTCS. I also participate in multi-center clinical and mechanistic research trials in the areas of chronic renal insufficiency, dialysis and transplantation. My work gets funding from NIH institutes (NIDDK, NIAID) and industry. I am particularly known for my work related to a post-transplant malignancy called post-transplant lymphoproliferative disorder (PTLD), caused in most cases by Epstein-Barr virus infection. These issues of infection and malignancy post-transplant have received a lot of attention as we gave our patients more immunosuppression in the hopes of reducing acute rejection rates. My collaborators are numerous. For the prospective clinical trials, my collaborators include pediatric nephrology colleagues at various centers such as Harvard, Johns Hopkins, University of Pennsylvania, UCSF, University of Washington and UAB. For my epidemiological studies, I collaborate with an adult nephrologist in the Army, with biostatisticians and epidemiologists at Emmes Corporation and with a biostatistician at UNOS.

Areas of Clinical Interest

Pediatric nephrology, pediatric dialysis, kidney transplantation, pediatric plasmapheresis, cellular apheresis, kidney biopsies, acute hemodialysis, peritoneal dialysis, kidney critical care, anemia management, bone mineral management.

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Research Output

Association between day of the week and medication adherence among adolescent and young adult kidney transplant recipients

Boucquemont, J., Pai, A. L. H., Dharnidharka, V. R., Hebert, D., Zelikovsky, N., Amaral, S., Furth, S. L. & Foster, B. J., Jan 1 2020, In : American Journal of Transplantation. 20, 1, p. 274-281 8 p.

Research output: Contribution to journalArticle

  • 1 Scopus citations

    Comparative Effectiveness of High-Dose Versus Standard-Dose Influenza Vaccine Among Patients Receiving Maintenance Hemodialysis

    Butler, A. M., Layton, J. B., Dharnidharka, V. R., Sahrmann, J. M., Seamans, M. J., Weber, D. J. & McGrath, L. J., Jan 2020, In : American Journal of Kidney Diseases. 75, 1, p. 72-83 12 p.

    Research output: Contribution to journalArticle

  • 5 Scopus citations

    Comparative safety of high-dose versus standard-dose influenza vaccination in patients with end-stage renal disease

    Layton, J. B., McGrath, L. J., Sahrmann, J. M., Ma, Y., Dharnidharka, V. R., O'Neil, C., Weber, D. J. & Butler, A. M., Jul 14 2020, In : Vaccine. 38, 33, p. 5178-5186 9 p.

    Research output: Contribution to journalArticle

  • Economic impacts of alternative kidney transplant immunosuppression: A national cohort study

    Axelrod, D. A., Caliskan, Y., Schnitzler, M. A., Xiao, H., Dharnidharka, V. R., Segev, D. L., McAdams-DeMarco, M., Brennan, D. C., Randall, H., Alhamad, T., Kasiske, B. L., Hess, G. & Lentine, K. L., Apr 1 2020, In : Clinical Transplantation. 34, 4, e13813.

    Research output: Contribution to journalArticle

  • Impacts of center and clinical factors in antihypertensive medication use after kidney transplantation

    Koraishy, F. M., Yamout, H., Naik, A. S., Zhang, Z., Schnitzler, M. A., Ouseph, R., Lam, N. N., Dharnidharka, V. R., Axelrod, D., Hess, G. P., Segev, D. L., Kasiske, B. L. & Lentine, K. L., Mar 1 2020, In : Clinical Transplantation. 34, 3, e13803.

    Research output: Contribution to journalArticle