Victor Davila-Roman

Professor of Medicine, Professor of Radiology, Professor of Anesthesiology

  • 9563 Citations
1991 …2019
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Personal profile

Research interests

Research interests include the study of hypertension (HTN), a disease that affects over 65 million Americans and one of the most common chronic diseases in the world. Hypertensive heart disease (HHD)-endophenotypes, including left ventricular hypertrophy, LV diastolic dysfunction, LV systolic dysfunction, and vascular hypertrophy are common and inter-related. Furthermore, HHD-endophenotypes are worsened by co-morbid conditions such as diabetes, obesity, metabolic syndrome, and dyslipidemia, thus suggesting that common underlying pathologic processes control/modulate these phenotypes through gene-gene and/or gene-environment interactions. Genes involved in myocardial metabolism and inflammation have been postulated as modulators of these highly complex endophenotypes. Through our large cardiovascular disease phenotype-genotype repository, we are conducting a genome-wide association study where important genes will be associated with quantitative HHD-endophenotypes.

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  • 28 Similar Profiles
Left Ventricular Function Medicine & Life Sciences
Echocardiography Medicine & Life Sciences
Heart Failure Medicine & Life Sciences
Transesophageal Echocardiography Medicine & Life Sciences
Thoracic Surgery Medicine & Life Sciences
Stress Echocardiography Medicine & Life Sciences
Cardiovascular Diseases Medicine & Life Sciences
Dobutamine Medicine & Life Sciences

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Research Output 1991 2019

2 Citations (Scopus)

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

Kraja, A., Liu, C., Fetterman, J. L., Graff, M., Have, C. T., Gu, C., Yanek, L. R., Feitosa, M. F., Arking, D. E., Chasman, D. I., Young, K., Ligthart, S., Hill, W. D., Weiss, S., Luan, J., Giulianini, F., Li-Gao, R., Hartwig, F. P., Lin, S. J., Wang, L. & 132 others, Richardson, T. G., Yao, J., Fernandez, E. P., Ghanbari, M., Wojczynski, M., Lee, W. J., Argos, M., Armasu, S. M., Barve, R. A., Ryan, K. A., An, P., Baranski, T., Bielinski, S. J., Bowden, D. W., Broeckel, U., Christensen, K., Chu, A. Y., Corley, J., Cox, S. R., Uitterlinden, A. G., Rivadeneira, F., Cropp, C. D., Daw, E. W., van Heemst, D., De Las Fuentes, L., Gao, H., Tzoulaki, I., Ahluwalia, T. S., de Mutsert, R., Emery, L. S., Erzurumluoglu, A. M., Perry, J. A., Fu, M., Forouhi, N. G., Gu, Z., Hai, Y., Harris, S. E., Hemani, G., Hunt, S. C., Irvin, M. R., Jonsson, A. E., Justice, A. E., Kerrison, N. D., Larson, N. B., Lin, K. H., Love-Gregory, L. D., Mathias, R. A., Lee, J. H., Nauck, M., Noordam, R., Ong, K. K., Pankow, J., Patki, A., Pattie, A., Petersmann, A., Qi, Q., Ribel-Madsen, R., Rohde, R., Sandow, K., Schnurr, T. M., Sofer, T., Starr, J. M., Taylor, A. M., Teumer, A., Timpson, N. J., de Haan, H. G., Wang, Y., Weeke, P. E., Williams, C., Wu, H., Yang, W., Zeng, D., Witte, D. R., Weir, B. S., Wareham, N. J., Vestergaard, H., Turner, S. T., Torp-Pedersen, C., Stergiakouli, E., Sheu, W. H. H., Rosendaal, F. R., Ikram, M. A., Franco, O. H., Ridker, P. M., Perls, T. T., Pedersen, O., Nohr, E. A., Newman, A. B., Linneberg, A., Langenberg, C., Kilpeläinen, T. O., Kardia, S. L. R., Jørgensen, M. E., Jørgensen, T., Sørensen, T. I. A., Homuth, G., Hansen, T., Goodarzi, M. O., Deary, I. J., Christensen, C., Chen, Y. D. I., Chakravarti, A., Brandslund, I., Bonnelykke, K., Taylor, K. D., Wilson, J. G., Rodriguez, S., Davies, G., Horta, B. L., Thyagarajan, B., Rao, DC., Grarup, N., Davila-Roman, V., Hudson, G., Guo, X., Arnett, D. K., Hayward, C., Vaidya, D., Mook-Kanamori, D. O., Tiwari, H. K., Levy, D., Loos, R. J. F., Dehghan, A., Elliott, P., Malik, A. N., Scott, R. A., Becker, D. M., de Andrade, M., Province, M., Meigs, J. B., Rotter, J. I. & North, K. E., Jan 3 2019, In : American journal of human genetics. 104, 1, p. 112-138 27 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Mitochondrial Genes
Mitochondria
Mitochondrial DNA
Genes
Waist-Hip Ratio
1 Citation (Scopus)

Dissemination and Implementation Program in Hypertension in Rwanda: Report on Initial Training and Evaluation

Baumann, A. A., Mutabazi, V., Brown, A., Hooley, C., Reeds, D., Ingabire, C., Ndahindwa, V., Nishimwe, A., Cade, T., De Las Fuentes, L., Proctor, E. K., Karengera, S., Schecthman, K. B., Goss, C. W., Yarasheski, K., Newsome, B., Mutimura, E. & Davila-Roman, V., Jun 1 2019, In : Global Heart. 14, 2, p. 135-141 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Rwanda
Hypertension
Cardiovascular Diseases
Biostatistics
Research

High-sensitivity cardiac troponin T increases after stress echocardiography

Samaha, E., Brown, J., Brown, F., Martinez, S. C., Scott, M., Jaffe, A. S., Davila-Roman, V. & Nagele, P., Jan 1 2019, In : Clinical Biochemistry. 63, p. 18-23 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Echocardiography
Stress Echocardiography
Troponin T
Dobutamine
Exercise

Low dose chloroquine decreases insulin resistance in human metabolic syndrome but does not reduce carotid intima-media thickness

McGill, J., Johnson, M., Hurst, S., Cade, T., Yarasheski, K. E., Ostlund, R., Schechtman, K., Razani, B., Kastan, M. B., McClain, D. A., De Las Fuentes, L., Davila-Roman, V., Ory, D., Wickline, S. A. & Semenkovich, C., Jul 29 2019, In : Diabetology and Metabolic Syndrome. 11, 1, 61.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Carotid Intima-Media Thickness
Chloroquine
Insulin Resistance
Ataxia Telangiectasia
Atherosclerosis

Research Education and Mentoring Program in Cardiovascular Diseases for Under-Represented Junior Faculty From NHLBI SIPID/PRIDE

Boutjdir, M., Aromolaran, A. S., De Las Fuentes, L., Boyington, J. E. A., Arteaga, S. S., Jobe, J., Jeffe, D., Rao, DC., Rice, T. & Davila-Roman, V., Apr 16 2019, In : Journal of the American College of Cardiology. 73, 14, p. 1861-1865 5 p.

Research output: Contribution to journalArticleResearchpeer-review

National Heart, Lung, and Blood Institute (U.S.)
Cardiovascular Diseases
Education
Research
Mentoring