Tunda Hidvegi

Associate Professor of Pediatrics

  • 1636 Citations
1985 …2019

Research output per year

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Research Output

An analog of glibenclamide selectively enhances autophagic degradation of misfolded α1-antitrypsin Z

Wang, Y., Cobanoglu, M. C., Li, J., Hidvegi, T., Hale, P., Ewing, M., Chu, A. S., Gong, Z., Muzumdar, R., Pak, S. C., Silverman, G. A., Bahar, I. & Perlmutter, D. H., Jan 2019, In : PloS one. 14, 1, e0209748.

Research output: Contribution to journalArticle

Open Access
  • 3 Scopus citations

    NFκB mitigates the pathological effects of misfolded α1-antitrypsin by activating autophagy and an integrated program of proteostasis mechanisms

    Mukherjee, A., Hidvegi, T., Araya, P., Ewing, M., Stolz, D. B. & Perlmutter, D. H., Mar 1 2019, In : Cell Death and Differentiation. 26, 3, p. 455-469 15 p.

    Research output: Contribution to journalArticle

  • 3 Scopus citations

    Enhancing autophagy with drugs or lung-directed gene therapy reverses the pathological effects of respiratory epithelial cell proteinopathy

    Hidvegi, T., Stolz, D. B., Alcorn, J. F., Yousem, S. A., Wang, J., Leme, A. S., Houghton, A. M. G., Hale, P., Ewing, M., Cai, H., Garchar, E. A., Pastore, N., Annunziata, P., Kaminski, N., Pilewski, J., Shapiro, S. D., Pak, S. C., Silverman, G. A., Brunetti-Pierri, N. & Perlmutter, D. H., Dec 11 2015, In : Journal of Biological Chemistry. 290, 50, p. 29742-29757 16 p.

    Research output: Contribution to journalArticle

    Open Access
  • 19 Scopus citations

    Fluphenazine reduces proteotoxicity in C. elegans and mammalian models of alpha-1-antitrypsin deficiency

    Li, J., Pak, S. C., O'Reilly, L. P., Benson, J. A., Wang, Y., Hidvegi, T., Hale, P., Dippold, C., Ewing, M., Silverman, G. A. & Perlmutter, D. H., Jan 31 2014, In : PloS one. 9, 1, e87260.

    Research output: Contribution to journalArticle

    Open Access
  • 20 Scopus citations

    Spontaneous hepatic repopulation in transgenic mice expressing mutant human α1-antitrypsin by wild-type donor hepatocytes

    Ding, J., Yannam, G. R., Roy-Chowdhury, N., Hidvegi, T., Basma, H., Rennard, S. I., Wong, R. J., Avsar, Y., Guha, C., Perlmutter, D. H., Fox, I. J. & Roy-Chowdhury, J., May 2 2011, In : Journal of Clinical Investigation. 121, 5, p. 1930-1934 5 p.

    Research output: Contribution to journalArticle

    Open Access
  • 47 Scopus citations