Treva Rice

Professor of Biostatistics, Professor of Psychiatry

    • 12197 Citations
    1986 …2020

    Research output per year

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    Personal profile

    Research interests

    Dr. Rice’s research interests include methodological issues related to defining / refining the measurement of complex traits through statistical methods, and in analytical / methodological issues underlying genetic studies, including genome-wide association study data. Her applied research is largely in genetic epidemiological investigations of traits related to the metabolic syndrome (obesity, diabetes, hypertension and lipids). She has published over 190 research articles in these areas. Dr. Rice is currently PI of a Data Coordinating Center for the GenSalt study, which is a dietary sodium intervention in hypertensive Chinese families. She is a Co-Investigator on other multi-center family and genetic studies (HyperGEN, HERITAGE). Dr. Rice also has active interests in training and mentoring activities. She is Co-Director for the Summer Institute Program to Increase Diversity (SIPID), and teaches in the SIPID program, in the Genetic Epidemiology Master of Science (GEMS) program, and in a summer training program for undergraduates (SIBS/Bridge).

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    Research Output

    Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

    Lifelines Cohort Study, 2020, (Accepted/In press) In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

    Sung, Y. J., De Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C. Y., Sim, X., Vojinovic, D., Marten, J. & 261 others, Musani, S. K., Kilpeläinen, T. O., Richard, M. A., Aslibekyan, S., Bartz, T. M., Dorajoo, R., Li, C., Liu, Y., Rankinen, T., Smith, A. V., Tajuddin, S. M., Tayo, B. O., Zhao, W., Zhou, Y., Matoba, N., Sofer, T., Alver, M., Amini, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Giulianini, F., Goel, A., Harris, S. E., Hartwig, F. P., He, M., Horimoto, A. R. V. R., Hsu, F. C., Jackson, A. U., Kammerer, C. M., Kasturiratne, A., Komulainen, P., Kühnel, B., Leander, K., Lee, W. J., Lin, K. H., Luan, J., Lyytikäinen, L. P., McKenzie, C. A., Nelson, C. P., Noordam, R., Scott, R. A., Sheu, W. H. H., Stančáková, A., Takeuchi, F., Van Der Most, P. J., Varga, T. V., Waken, R. J., Wang, H., Wang, Y., Ware, E. B., Weiss, S., Wen, W., Yanek, L. R., Zhang, W., Zhao, J. H., Afaq, S., Alfred, T., Amin, N., Arking, D. E., Aung, T., Barr, R. G., Bielak, L. F., Boerwinkle, E., Bottinger, E. P., Braund, P. S., Brody, J. A., Broeckel, U., Cade, B., Campbell, A., Canouil, M., Chakravarti, A., Cocca, M., Collins, F. S., Connell, J. M., De Mutsert, R., De Silva, H. J., Dörr, M., Duan, Q., Eaton, C. B., Ehret, G., Evangelou, E., Faul, J. D., Forouhi, N. G., Franco, O. H., Friedlander, Y., Gao, H., Gigante, B., Gu, C. C., Gupta, P., Hagenaars, S. P., Harris, T. B., He, J., Heikkinen, S., Heng, C. K., Hofman, A., Howard, B. V., Hunt, S. C., Irvin, M. R., Jia, Y., Katsuya, T., Kaufman, J., Kerrison, N. D., Khor, C. C., Koh, W. P., Koistinen, H. A., Kooperberg, C. B., Krieger, J. E., Kubo, M., Kutalik, Z., Kuusisto, J., Lakka, T. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lee, J. H., Lehne, B., Levy, D., Lewis, C. E., Li, Y., Lim, S. H., Liu, C. T., Liu, J., Liu, J., Liu, Y., Loh, M., Lohman, K. K., Louie, T., Mägi, R., Matsuda, K., Meitinger, T., Metspalu, A., Milani, L., Momozawa, Y., Thomas, T. H., Nalls, M. A., Nasri, U., O'Connell, J. R., Ogunniyi, A., Palmas, W. R., Palmer, N. D., Pankow, J. S., Pedersen, N. L., Peters, A., Peyser, P. A., Polasek, O., Porteous, D., Raitakari, O. T., Renström, F., Rice, T. K., Ridker, P. M., Robino, A., Robinson, J. G., Rose, L. M., Rudan, I., Sabanayagam, C., Salako, B. L., Sandow, K., Schmidt, C. O., Schreiner, P. J., Scott, W. R., Sever, P., Sims, M., Sitlani, C. M., Smith, B. H., Smith, J. A., Snieder, H., Starr, J. M., Strauch, K., Tang, H., Taylor, K. D., Teo, Y. Y., Tham, Y. C., Uitterlinden, A. G., Waldenberger, M., Wang, L., Wang, Y. X., Wei, W. B., Wilson, G., Wojczynski, M. K., Xiang, Y. B., Yao, J., Yuan, J. M., Zonderman, A. B., Becker, D. M., Boehnke, M., Bowden, D. W., Chambers, J. C., Chen, Y. D. I., Weir, D. R., De Faire, U., Deary, I. J., Esko, T., Farrall, M., Forrester, T., Freedman, B. I., Froguel, P., Gasparini, P., Gieger, C., Horta, B. L., Hung, Y. J., Jonas, J. B., Kato, N., Kooner, J. S., Laakso, M., Lehtimäki, T., Liang, K. W., Magnusson, P. K. E., Oldehinkel, A. J., Pereira, A. C., Perls, T., Rauramaa, R., Redline, S., Rettig, R., Samani, N. J., Scott, J., Shu, X. O., Van Der Harst, P., Wagenknecht, L. E., Wareham, N. J., Watkins, H., Wickremasinghe, A. R., Wu, T., Kamatani, Y., Laurie, C. C., Bouchard, C., Cooper, R. S., Evans, M. K., Gudnason, V., Hixson, J., Kardia, S. L. R., Kritchevsky, S. B., Psaty, B. M., Van Dam, R. M., Arnett, D. K., Mook-Kanamori, D. O., Fornage, M., Fox, E. R., Hayward, C., Van Duijn, C. M., Tai, E. S., Wong, T. Y., Loos, R. J. F., Reiner, A. P., Rotimi, C. N., Bierut, L. J., Zhu, X., Cupples, L. A., Province, M. A., Rotter, J. I., Franks, P. W., Rice, K., Elliott, P., Caulfield, M. J., Gauderman, W. J., Munroe, P. B., Rao, D. C. & Morrison, A. C., Aug 1 2019, In : Human molecular genetics. 28, 15, p. 2615-2633 19 p.

    Research output: Contribution to journalArticle

  • 4 Scopus citations

    Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

    De Vries, P. S., Brown, M. R., Bentley, A. R., Sung, Y. J., Winkler, T. W., Ntalla, I., Schwander, K., Kraja, A. T., Guo, X., Franceschini, N., Cheng, C. Y., Sim, X., Vojinovic, D., Huffman, J. E., Musani, S. K., Li, C., Feitosa, M. F., Richard, M. A., Noordam, R., Aschard, H. & 246 others, Bartz, T. M., Bielak, L. F., Deng, X., Dorajoo, R., Lohman, K. K., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Evangelou, E., Graff, M., Alver, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Goel, A., Hagemeijer, Y., Harris, S. E., Hartwig, F. P., He, M., Horimoto, A. R. V. R., Hsu, F. C., Jackson, A. U., Kasturiratne, A., Komulainen, P., Kühnel, B., Laguzzi, F., Lee, J. H., Luan, JA., Lyytikäinen, L. P., Matoba, N., Nolte, I. M., Pietzner, M., Riaz, M., Said, M. A., Scott, R. A., Sofer, T., Stančáková, A., Takeuchi, F., Tayo, B. O., Van Der Most, P. J., Varga, T. V., Wang, Y., Ware, E. B., Wen, W., Yanek, L. R., Zhang, W., Zhao, J. H., Afaq, S., Amin, N., Amini, M., Arking, D. E., Aung, T., Ballantyne, C., Boerwinkle, E., Broeckel, U., Campbell, A., Canouil, M., Charumathi, S., Chen, Y. D. I., Connell, J. M., De Faire, U., De Las Fuentes, L., De Mutsert, R., De Silva, H. J., Ding, J., Dominiczak, A. F., Duan, Q., Eaton, C. B., Eppinga, R. N., Faul, J. D., Fisher, V., Forrester, T., Franco, O. H., Friedlander, Y., Ghanbari, M., Giulianini, F., Grabe, H. J., Grove, M. L., Gu, C. C., Harris, T. B., Heikkinen, S., Heng, C. K., Hirata, M., Hixson, J. E., Howard, B. V., Ikram, M. A., Jacobs, D. R., Johnson, C., Jonas, J. B., Kammerer, C. M., Katsuya, T., Khor, C. C., Kilpeläinen, T. O., Koh, W. P., Koistinen, H. A., Kolcic, I., Kooperberg, C., Krieger, J. E., Kritchevsky, S. B., Kubo, M., Kuusisto, J., Lakka, T. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lehne, B., Lemaitre, R. N., Li, Y., Liang, J., Liu, J., Liu, K., Loh, M., Louie, T., Mägi, R., Manichaikul, A. W., McKenzie, C. A., Meitinger, T., Metspalu, A., Milaneschi, Y., Milani, L., Mohlke, K. L., Mosley, T. H., Mukamal, K. J., Nalls, M. A., Nauck, M., Nelson, C. P., Sotoodehnia, N., O'Connell, J. R., Palmer, N. D., Pazoki, R., Pedersen, N. L., Peters, A., Peyser, P. A., Polasek, O., Poulter, N., Raffel, L. J., Raitakari, O. T., Reiner, A. P., Rice, T. K., Rich, S. S., Robino, A., Robinson, J. G., Rose, L. M., Rudan, I., Schmidt, C. O., Schreiner, P. J., Scott, W. R., Sever, P., Shi, Y., Sidney, S., Sims, M., Smith, B. H., Smith, J. A., Snieder, H., Starr, J. M., Strauch, K., Tan, N., Taylor, K. D., Teo, Y. Y., Tham, Y. C., Uitterlinden, A. G., Van Heemst, D., Vuckovic, D., Waldenberger, M., Wang, L., Wang, Y., Wang, Z., Wei, W. B., Williams, C., Wilson, G., Wojczynski, M. K., Yao, J., Yu, B., Yu, C., Yuan, J. M., Zhao, W., Zonderman, A. B., Becker, D. M., Boehnke, M., Bowden, D. W., Chambers, J. C., Deary, I. J., Esko, T., Farrall, M., Franks, P. W., Freedman, B. I., Froguel, P., Gasparini, P., Gieger, C., Horta, B. L., Kamatani, Y., Kato, N., Kooner, J. S., Laakso, M., Leander, K., Lehtimäki, T., Magnusson, P. K. E., Penninx, B., Pereira, A. C., Rauramaa, R., Samani, N. J., Scott, J., Shu, X. O., Van Der Harst, P., Wagenknecht, L. E., Wang, Y. X., Wareham, N. J., Watkins, H., Weir, D. R., Wickremasinghe, A. R., Zheng, W., Elliott, P., North, K. E., Bouchard, C., Evans, M. K., Gudnason, V., Liu, C. T., Liu, Y., Psaty, B. M., Ridker, P. M., Van Dam, R. M., Kardia, S. L. R., Zhu, X., Rotimi, C. N., Mook-Kanamori, D. O., Fornage, M., Kelly, T. N., Fox, E. R., Hayward, C., Van Duijn, C. M., Tai, E. S., Wong, T. Y., Liu, J., Rotter, J. I., Gauderman, W. J., Province, M. A., Munroe, P. B., Rice, K., Chasman, D. I., Cupples, L. A., Rao, D. C. & Morrison, A. C., Jun 1 2019, In : American journal of epidemiology. 188, 6, p. 1033-1054 22 p.

    Research output: Contribution to journalArticle

    Open Access
  • 12 Scopus citations

    Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

    Understanding Society Scientific group, Lifelines Cohort, COGENT-Kidney Consortium & EPIC-InterAct Consortium, Apr 1 2019, In : Nature Genetics. 51, 4, p. 636-648 13 p.

    Research output: Contribution to journalArticle

  • 25 Scopus citations

    Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

    Noordam, R., Bos, M. M., Wang, H., Winkler, T. W., Bentley, A. R., Kilpeläinen, T. O., de Vries, P. S., Sung, Y. J., Schwander, K., Cade, B. E., Manning, A., Aschard, H., Brown, M. R., Chen, H., Franceschini, N., Musani, S. K., Richard, M., Vojinovic, D., Aslibekyan, S., Bartz, T. M. & 128 others, de las Fuentes, L., Feitosa, M., Horimoto, A. R., Ilkov, M., Kho, M., Kraja, A., Li, C., Lim, E., Liu, Y., Mook-Kanamori, D. O., Rankinen, T., Tajuddin, S. M., van der Spek, A., Wang, Z., Marten, J., Laville, V., Alver, M., Evangelou, E., Graff, M. E., He, M., Kühnel, B., Lyytikäinen, L. P., Marques-Vidal, P., Nolte, I. M., Palmer, N. D., Rauramaa, R., Shu, X. O., Snieder, H., Weiss, S., Wen, W., Yanek, L. R., Adolfo, C., Ballantyne, C., Bielak, L., Biermasz, N. R., Boerwinkle, E., Dimou, N., Eiriksdottir, G., Gao, C., Gharib, S. A., Gottlieb, D. J., Haba-Rubio, J., Harris, T. B., Heikkinen, S., Heinzer, R., Hixson, J. E., Homuth, G., Ikram, M. A., Komulainen, P., Krieger, J. E., Lee, J., Liu, J., Lohman, K. K., Luik, A. I., Mägi, R., Martin, L. W., Meitinger, T., Metspalu, A., Milaneschi, Y., Nalls, M. A., O’Connell, J., Peters, A., Peyser, P., Raitakari, O. T., Reiner, A. P., Rensen, P. C. N., Rice, T. K., Rich, S. S., Roenneberg, T., Rotter, J. I., Schreiner, P. J., Shikany, J., Sidney, S. S., Sims, M., Sitlani, C. M., Sofer, T., Strauch, K., Swertz, M. A., Taylor, K. D., Uitterlinden, A. G., van Duijn, C. M., Völzke, H., Waldenberger, M., Wallance, R. B., van Dijk, K. W., Yu, C., Zonderman, A. B., Becker, D. M., Elliott, P., Esko, T., Gieger, C., Grabe, H. J., Lakka, T. A., Lehtimäki, T., North, K. E., Penninx, B. W. J. H., Vollenweider, P., Wagenknecht, L. E., Wu, T., Xiang, Y. B., Zheng, W., Arnett, D. K., Bouchard, C., Evans, M. K., Gudnason, V., Kardia, S., Kelly, T. N., Kritchevsky, S. B., Loos, R. J. F., Pereira, A. C., Province, M., Psaty, B. M., Rotimi, C., Zhu, X., Amin, N., Cupples, L. A., Fornage, M., Fox, E. F., Guo, X., Gauderman, W. J., Rice, K., Kooperberg, C., Munroe, P. B., Liu, C. T., Morrison, A. C., Rao, D. C., van Heemst, D. & Redline, S., Dec 1 2019, In : Nature communications. 10, 1, 5121.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Scopus citations