Personal profile
Research interests
My overall goal as a researcher is to study the molecular and cellular mechanisms that underlie the regulation of intrinsic neuronal excitability and how neurons, in a system, come together and coordinate specific behaviors. In particular, I am interested in identifying the molecular determinants and cellular mechanisms that underlie the rhythmic oscillations in neuronal excitability in the suprachiasmatic nucleus (SCN), and I’m focused on understanding the physiological role repetitive firing rates play in adult SCN neurons in maintaining circadian rhythmicity in an intact animal.
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Collaborations and top research areas from the last five years
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Effects of NALCN-Encoded Na1 Leak Currents on the Repetitive Firing Properties of SCN Neurons Depend on K+ Driven Rhythmic Changes in Input Resistance
Yang, N. D., Mellor, R. L., Hermanstyne, T. O. & Nerbonne, J. M., Jul 12 2023, In: Journal of Neuroscience. 43, 28, p. 5132-5141 10 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
Kv12-encoded K+ channels drive the day–night switch in the repetitive firing rates of SCN neurons
Hermanstyne, T. O., Yang, N. D., Granados-Fuentes, D., Li, X., Mellor, R. L., Jegla, T., Herzog, E. D. & Nerbonne, J. M., Sep 4 2023, In: Journal of General Physiology. 155, 9, e202213310.Research output: Contribution to journal › Article › peer-review
Open Access10 Link opens in a new tab Scopus citations -
Helping others enhances graduate student wellness and mental health
Hermanstyne, T. O., Johnson, L., Wylie, K. M. & Skeath, J. B., Apr 1 2022, In: Nature Biotechnology. 40, 4, p. 618-619 2 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Link opens in a new tab Scopus citations -
Understanding Circadian Mechanisms of Sudden Cardiac Death: A Report From the National Heart, Lung, and Blood Institute Workshop, Part 2: Population and Clinical Considerations
Delisle, B. P., George, A. L., Nerbonne, J. M., Bass, J. T., Ripplinger, C. M., Jain, M. K., Hermanstyne, T. O., Young, M. E., Kannankeril, P. J., Duffy, J. F., Goldhaber, J. I., Hall, M. H., Somers, V. K., Smolensky, M. H., Garnett, C. E., Anafi, R. C., Scheer, F. A. J. L., Shivkumar, K., Shea, S. A. & Balijepalli, R. C., Nov 1 2021, In: Circulation: Arrhythmia and Electrophysiology. 14, 11, p. E010190Research output: Contribution to journal › Review article › peer-review
Open Access12 Link opens in a new tab Scopus citations -
Understanding Circadian Mechanisms of Sudden Cardiac Death: A Report From the National Heart, Lung, and Blood Institute Workshop, Part 1: Basic and Translational Aspects
Delisle, B. P., George, A. L., Nerbonne, J. M., Bass, J. T., Ripplinger, C. M., Jain, M. K., Hermanstyne, T. O., Young, M. E., Kannankeril, P. J., Duffy, J. F., Goldhaber, J. I., Hall, M. H., Somers, V. K., Smolensky, M. H., Garnett, C. E., Anafi, R. C., Scheer, F. A. J. L., Shivkumar, K., Shea, S. A. & Balijepalli, R. C., Nov 1 2021, In: Circulation: Arrhythmia and Electrophysiology. 14, 11, p. E010181Research output: Contribution to journal › Review article › peer-review
Open Access15 Link opens in a new tab Scopus citations