Personal profile
Research interests
I study mucosal immunity to bacterial pathogens. In particular, I utilize a murine model of chronic urinary tract infection with uropathogenic E. coli to understand the mucosal immune responses of the urinary bladder and how these host responses affect disease outcome.
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Mechanisms of uropathogenic E. coli mucosal association in the gastrointestinal tract
Azimzadeh, P. N., Birchenough, G. M., Gualbuerto, N. C., Pinkner, J. S., Tamadonfar, K. O., Beatty, W., Hannan, T. J., Dodson, K. W., Ibarra, E. C., Kim, S., Schreiber, H. L., Janetka, J. W., Kau, A. L., Earl, A. M., Miller, M. J., Hansson, G. C. & Hultgren, S. J., Jan 31 2025, In: Science Advances. 11, 5, eadp7066.Research output: Contribution to journal › Article › peer-review
Open Access11 Link opens in a new tab Scopus citations -
METs, NETs, and UTIs
Hannan, T. J., Mar 12 2025, In: Cell Host and Microbe. 33, 3, p. 318-320 3 p.Research output: Contribution to journal › Comment/debate
2 Link opens in a new tab Scopus citations -
Chronic urinary tract infections cause persistent microglial changes in a humanized ɑ-synuclein mouse model
Mercado, G., Clabout, A. C., Howland, V., Arkin, E., Janer, A. B., Plessers, D., Steiner, J. A., Smith, W. W., Hannan, T., Brundin, P. & Peelaerts, W., Nov 1 2024, In: Journal of Parkinson's Disease. 14, 8, p. 1559-1574 16 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Secretory leukocyte protease inhibitor protects against severe urinary tract infection in mice
Rosen, A. L., Lint, M. A., Voelker, D. H., Gilbert, N. M., Tomera, C. P., Santiago-Borges, J., Wallace, M. A., Hannan, T. J., Burnham, C. A. D., Hultgren, S. J. & Kau, A. L., Feb 2024, In: mBio. 15, 2Research output: Contribution to journal › Article › peer-review
Open Access6 Link opens in a new tab Scopus citations -
Urinary tract infections trigger synucleinopathy via the innate immune response
Peelaerts, W., Mercado, G., George, S., Villumsen, M., Kasen, A., Aguileta, M., Linstow, C., Sutter, A. B., Kuhn, E., Stetzik, L., Sheridan, R., Bergkvist, L., Meyerdirk, L., Lindqvist, A., Gavis, M. L. E., Van den Haute, C., Hultgren, S. J., Baekelandt, V., Pospisilik, J. A. & Brudek, T. & 7 others, , May 2023, In: Acta Neuropathologica. 145, 5, p. 541-559 19 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Link opens in a new tab Scopus citations