Research output per year
Research output per year
Personal profile
Research interests
I study mucosal immunity to bacterial pathogens. In particular, I utilize a murine model of chronic urinary tract infection with uropathogenic E. coli to understand the mucosal immune responses of the urinary bladder and how these host responses affect disease outcome.
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Collaborations and top research areas from the last five years
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Secretory leukocyte protease inhibitor protects against severe urinary tract infection in mice
Rosen, A. L., Lint, M. A., Voelker, D. H., Gilbert, N. M., Tomera, C. P., Santiago-Borges, J., Wallace, M. A., Hannan, T. J., Burnham, C. A. D., Hultgren, S. J. & Kau, A. L., Feb 2024, In: mBio. 15, 2Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Urinary tract infections trigger synucleinopathy via the innate immune response
Peelaerts, W., Mercado, G., George, S., Villumsen, M., Kasen, A., Aguileta, M., Linstow, C., Sutter, A. B., Kuhn, E., Stetzik, L., Sheridan, R., Bergkvist, L., Meyerdirk, L., Lindqvist, A., Gavis, M. L. E., Van den Haute, C., Hultgren, S. J., Baekelandt, V., Pospisilik, J. A. & Brudek, T. & 7 others, , May 2023, In: Acta Neuropathologica. 145, 5, p. 541-559 19 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Uropathogenic Escherichia coli infection-induced epithelial trained immunity impacts urinary tract disease outcome
Russell, S. K., Harrison, J. K., Olson, B. S., Lee, H. J., O’Brien, V. P., Xing, X., Livny, J., Yu, L., Roberson, E. D. O., Bomjan, R., Fan, C., Sha, M., Estfanous, S., Amer, A. O., Colonna, M., Stappenbeck, T. S., Wang, T., Hannan, T. J. & Hultgren, S. J., May 2023, In: Nature microbiology. 8, 5, p. 875-888 14 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Longitudinal multi-omics analyses link gut microbiome dysbiosis with recurrent urinary tract infections in women
Worby, C. J., Schreiber, H. L., Straub, T. J., van Dijk, L. R., Bronson, R. A., Olson, B. S., Pinkner, J. S., Obernuefemann, C. L. P., Muñoz, V. L., Paharik, A. E., Azimzadeh, P. N., Walker, B. J., Desjardins, C. A., Chou, W. C., Bergeron, K., Chapman, S. B., Klim, A., Manson, A. L., Hannan, T. J. & Hooton, T. M. & 5 others, , May 2022, In: Nature microbiology. 7, 5, p. 630-639 10 p.Research output: Contribution to journal › Article › peer-review
Open Access69 Scopus citations -
Mucosal infection rewires TNFα signaling dynamics to skew susceptibility to recurrence
Yu, L., O’Brien, V. P., Livny, J., Dorsey, D., Bandyopadhyay, N., Colonna, M., Caparon, M. G., Roberson, E. D. O., Hultgren, S. J. & Hannan, T. J., Aug 2019, In: eLife. 8, e46677.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations