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Personal profile

Research interests

Development genetics of the germ cells, including germline stem cells, meiotic prophase entry and progression and gametogenesis. The use of the C. elegans system to model human disease and test the functional significance of human coding sequence variation.

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Research Output

De novo EIF2AK1 and EIF2AK2 Variants Are Associated with Developmental Delay, Leukoencephalopathy, and Neurologic Decompensation

Undiagnosed Diseases Network, Apr 2 2020, In : American journal of human genetics. 106, 4, p. 570-583 14 p.

Research output: Contribution to journalArticle

  • GLP-1 Notch-LAG-1 CSL control of the germline stem cell fate is mediated by transcriptional targets lst-1 and sygl-1

    Chen, J., Mohammad, A., Pazdernik, N., Huang, H., Bowman, B., Tycksen, E. & Schedl, T., Mar 1 2020, In : PLoS genetics. 16, 3, e1008650.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations

    WormBase: A modern Model Organism Information Resource

    Harris, T. W., Arnaboldi, V., Cain, S., Chan, J., Chen, W. J., Cho, J., Davis, P., Gao, S., Grove, C. A., Kishore, R., Lee, R. Y. N., Muller, H. M., Nakamura, C., Nuin, P., Paulini, M., Raciti, D., Rodgers, F. H., Russell, M., Schindelman, G., Auken, K. V. & 8 others, Wang, Q., Williams, G., Wright, A. J., Yook, K., Howe, K. L., Schedl, T., Stein, L. & Sternberg, P. W., Jan 1 2020, In : Nucleic acids research. 48, D1, p. D762-D767

    Research output: Contribution to journalArticle

    Open Access
  • 17 Scopus citations

    Biology of the caenorhabditis elegans germline stem cell system

    Albert Hubbard, E. J. & Schedl, T., Jan 1 2019, In : Genetics. 213, 4, p. 1145-1188 44 p.

    Research output: Contribution to journalArticle

  • 7 Scopus citations
  • 1 Scopus citations