Tiantian Liu

2024

Transcription factor C/EBPα is required for the development of Ly6C^hi monocytes but not Ly6C^lo monocytes

Kim, S., Chen, J., Ou, F., Liu, T. T., Jo, S., Gillanders, W. E., Murphy, T. L. & Murphy, K. M., Apr 9 2024, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 15, e2315659121.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

2023

Bcl6, Irf2, and Notch2 promote nonclassical monocyte development

O'Connor, K. W., Liu, T., Kim, S., Briseño, C. G., Georgopoulos, K., Murphy, T. L. & Murphy, K. M., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 35, e2220853120.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Cis interactions in the Irf8 locus regulate stage-dependent enhancer activation

Liu, T. T., Ou, F., Belk, J. A., Bagadia, P., Anderson, D. A., Durai, V., Yao, W., Satpathy, A. T., Murphy, T. L. & Murphy, K. M., 2023, In: Genes and Development. 37, 7-8, p. 291-302 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Enhanced in vitro type 1 conventional dendritic cell generation via the recruitment of hematopoietic stem cells and early progenitors by Kit ligand

Ou, F., Ferris, S. T., Kim, S., Wu, R., Anderson, D. A., Liu, T. T., Jo, S., Chen, M. Y., Gillanders, W. E., Murphy, T. L. & Murphy, K. M., Sep 2023, In: European Journal of Immunology. 53, 9, 2250201.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

IL-6 selectively suppresses cDC1 specification via C/EBPβ

Kim, S., Chen, J., Jo, S., Ou, F., Ferris, S. T., Liu, T. T., Ohara, R. A., Anderson, D. A., Wu, R., Chen, M. Y., Gillanders, W. E., Gillanders, W. E., Murphy, T. L. & Murphy, K. M., Oct 2 2023, In: Journal of Experimental Medicine. 220, 10, e20221757.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

WDFY4 deficiency in NOD mice ameliorates autoimmune diabetes and insulitis

Ferris, S. T., Liu, T., Chen, J., Ohara, R. A., Ou, F., Wu, R., Kim, S., Murphy, T. L. & Murphy, K. M., Mar 28 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 13, e2219956120.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

2022

Ablation of cDC2 development by triple mutations within the Zeb2 enhancer

Liu, T. T., Kim, S., Desai, P., Kim, D. H., Huang, X., Ferris, S. T., Wu, R., Ou, F., Egawa, T., Van Dyken, S. J., Diamond, M. S., Johnson, P. F., Kubo, M., Murphy, T. L. & Murphy, K. M., Jul 7 2022, In: Nature. 607, 7917, p. 142-148 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

42 Scopus citations

cDC1 Vaccines Drive Tumor Rejection by Direct Presentation Independently of Host cDC1

Ferris, S. T., Ohara, R. A., Ou, F., Wu, R., Huang, X., Kim, S., Chen, J., Liu, T. T., Schreiber, R. D., Murphy, T. L. & Murphy, K. M., Aug 2022, In: Cancer immunology research. 10, 8, p. 920-931 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

Mechanisms of CD40-dependent cDC1 licensing beyond costimulation

Wu, R., Ohara, R. A., Jo, S., Liu, T. T., Ferris, S. T., Ou, F., Kim, S., Theisen, D. J., Anderson, D. A., Wong, B. W., Gershon, T., Schreiber, R. D., Murphy, T. L. & Murphy, K. M., Nov 2022, In: Nature immunology. 23, 11, p. 1536-1550 15 p.

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

2021

Differential usage of transcriptional repressor Zeb2 enhancers distinguishes adult and embryonic hematopoiesis

Huang, X., Ferris, S. T., Kim, S., Choudhary, M. N. K., Belk, J. A., Fan, C., Qi, Y., Sudan, R., Xia, Y., Desai, P., Chen, J., Ly, N., Shi, Q., Bagadia, P., Liu, T., Guilliams, M., Egawa, T., Colonna, M., Diamond, M. S. & Murphy, T. L. & 3 others, Satpathy, A. T., Wang, T. & Murphy, K. M., Jul 13 2021, In: Immunity. 54, 7, p. 1417-1432.e7

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

2020

cDC1 prime and are licensed by CD4⁺ T cells to induce anti-tumour immunity

Ferris, S. T., Durai, V., Wu, R., Theisen, D. J., Ward, J. P., Bern, M. D., Davidson, J. T., Bagadia, P., Liu, T., Briseño, C. G., Li, L., Gillanders, W. E., Wu, G. F., Yokoyama, W. M., Murphy, T. L., Schreiber, R. D. & Murphy, K. M., Aug 27 2020, In: Nature. 584, 7822, p. 624-629 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

314 Scopus citations

High Amount of Transcription Factor IRF8 Engages AP1-IRF Composite Elements in Enhancers to Direct Type 1 Conventional Dendritic Cell Identity

Kim, S., Bagadia, P., Anderson, D. A., Liu, T. T., Huang, X., Theisen, D. J., O'Connor, K. W., Ohara, R. A., Iwata, A., Murphy, T. L. & Murphy, K. M., Oct 13 2020, In: Immunity. 53, 4, p. 759-774.e9

Research output: Contribution to journal › Article › peer-review

Open Access

48 Scopus citations

2019

An Nfil3–Zeb2–Id2 pathway imposes Irf8 enhancer switching during cDC1 development

Bagadia, P., Huang, X., Liu, T. T., Durai, V., Grajales-Reyes, G. E., Nitschké, M., Modrusan, Z., Granja, J. M., Satpathy, A. T., Briseño, C. G., Gargaro, M., Iwata, A., Kim, S., Chang, H. Y., Shaw, A. S., Murphy, T. L. & Murphy, K. M., Sep 1 2019, In: Nature immunology. 20, 9, p. 1174-1185 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

79 Scopus citations

Cryptic activation of an Irf8 enhancer governs cDC1 fate specification

Durai, V., Bagadia, P., Granja, J. M., Satpathy, A. T., Kulkarni, D. H., Davidson, J. T., Wu, R., Patel, S. J., Iwata, A., Liu, T. T., Huang, X., Briseño, C. G., Grajales-Reyes, G. E., Wöhner, M., Tagoh, H., Kee, B. L., Newberry, R. D., Busslinger, M., Chang, H. Y. & Murphy, T. L. & 1 others, Murphy, K. M., Sep 1 2019, In: Nature immunology. 20, 9, p. 1161-1173 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

103 Scopus citations

FAM64A positively regulates STAT3 activity to promote Th17 differentiation and colitisassociated carcinogenesis

Xu, Z. S., Zhang, H. X., Li, W. W., Ran, Y., Liu, T. T., Xiong, M. G., Li, Q. L., Wang, S. Y., Wu, M., Shu, H. B., Xia, H. & Wang, Y. Y., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 21, p. 10447-10452 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

41 Scopus citations

2017

TRIM32-TAX1BP1-dependent selective autophagic degradation of TRIF negatively regulates TLR3/4-mediated innate immune responses

Yang, Q., Liu, T. T., Lin, H., Zhang, M., Wei, J., Luo, W. W., Hu, Y. H., Zhong, B., Hu, M. M. & Shu, H. B., Sep 2017, In: PLoS pathogens. 13, 9, e1006600.

Research output: Contribution to journal › Article › peer-review

Open Access

91 Scopus citations

2016

LSm14A plays a critical role in antiviral immune responses by regulating MITA level in a cell-specific manner

Liu, T. T., Yang, Q., Li, M., Zhong, B., Ran, Y., Liu, L. L., Yang, Y., Wang, Y. Y. & Shu, H. B., Jun 15 2016, In: Journal of Immunology. 196, 12, p. 5101-5111 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

PASD1 promotes STAT3 activity and tumor growth by inhibiting TC45-mediated dephosphorylation of STAT3 in the nucleus

Xu, Z. S., Zhang, H. X., Zhang, Y. L., Liu, T. T., Ran, Y., Chen, L. T., Wang, Y. Y. & Shu, H. B., Jun 1 2016, In: Journal of Molecular Cell Biology. 8, 3, p. 221-231 11 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Sumoylation Promotes the Stability of the DNA Sensor cGAS and the Adaptor STING to Regulate the Kinetics of Response to DNA Virus

Hu, M. M., Yang, Q., Xie, X. Q., Liao, C. Y., Lin, H., Liu, T. T., Yin, L. & Shu, H. B., Sep 20 2016, In: Immunity. 45, 3, p. 555-569 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

269 Scopus citations

2011

SENP2 negatively regulates cellular antiviral response by deSUMOylating IRF3 and conditioning it for ubiquitination and degradation

Ran, Y., Liu, T. T., Zhou, Q., Li, S., Mao, A. P., Li, Y., Liu, L. J., Cheng, J. K. & Shu, H. B., Oct 2011, In: Journal of Molecular Cell Biology. 3, 5, p. 283-292 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

70 Scopus citations

2010

The E3 ubiquitin ligase RNF5 targets virus-induced signaling adaptor for ubiquitination and degradation

Zhong, B., Zhang, Y., Tan, B., Liu, T. T., Wang, Y. Y. & Shu, H. B., Jun 1 2010, In: Journal of Immunology. 184, 11, p. 6249-6255 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

155 Scopus citations

WDR5 is essential for assembly of the VISA-associated signaling complex and virus-triggered IRF3 and NF-κB activation

Wang, Y. Y., Liu, L. J., Zhong, B., Liu, T. T., Li, Y., Yang, Y., Ran, Y., Li, S., Tien, P. & Shu, H. B., 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 2, p. 815-820 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

81 Scopus citations

Tiantian Liu

Research output

Search results