Thomas Conturo

Associate Professor of Radiology, Adjunct Associate Professor of Physics

    • 9678 Citations
    1982 …2019

    Research output per year

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    Personal profile

    Research interests

    Magnetic resonance (MR) imaging is a noninvasive means of providing images of the human body at high spatial resolution and contrast sensitivity. The contrast can be manipulated to depend on different properties of tissue water, enabling the study of a variety of biological processes. In some cases, endogenous or exogenous paramagnetic MR contrast agents are used to alter the MRI contrast by perturbing the tissue water environment. Recently, new MRI hardware has also enabled techniques having high temporal resolution. Using the unique contrast properties of MRI and the higher spatial/temporal resolution, noninvasive techniques can be devised to study neuronal activity, tissue perfusion, water mobility (diffusion), and neuronal fiber pathways in the human brain. The goals of Dr. Conturo's research lab are to develop and apply MR imaging techniques for quantitative imaging of cerebral perfusion, brain function, water diffusion, and neuronal fiber pathways. These techniques utilize the MR signal effects of exogenous bolus-injected contrast agents, endogenous hemoglobin, and microscopic water diffusion. Long-term goals are to apply these methodologies toward imaging and understanding human brain structure, function, and physiology in normal and abnormal conditions. The approaches that are used in this laboratory cover a broad range of areas, including MRI physics, MRI pulse sequence development, theoretical derivations, computer simulations, image-processing, computer graphics, custom contrast agents, phantom studies, animal models, human studies, clinical patient studies, and comparison with other imaging modalities.

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    Research Output

    • 9678 Citations
    • 71 Article
    • 2 Letter
    • 1 Comment/debate
    • 1 Review article

    Behavioral inhibition corresponds to white matter fiber bundle integrity in older adults

    Garcia-Egan, P. M., Preston-Campbell, R. N., Salminen, L. E., Heaps-Woodruff, J. M., Balla, L., Cabeen, R. P., Laidlaw, D. H., Conturo, T. E. & Paul, R. H., Dec 1 2019, In : Brain Imaging and Behavior. 13, 6, p. 1602-1611 10 p.

    Research output: Contribution to journalArticle

  • Predicting and grouping digitized paintings by style using unsupervised feature learning

    Gultepe, E., Edward. Conturo, T. & Makrehchi, M., May 1 2018, In : Journal of Cultural Heritage. 31, p. 13-23 11 p.

    Research output: Contribution to journalArticle

  • 9 Scopus citations

    Cognitive reserve moderates the relationship between neuropsychological performance and white matter fiber bundle length in healthy older adults

    Baker, L. M., Laidlaw, D. H., Cabeen, R., Akbudak, E., Conturo, T. E., Correia, S., Tate, D. F., Heaps-Woodruff, J. M., Brier, M. R., Bolzenius, J., Salminen, L. E., Lane, E. M., McMichael, A. R. & Paul, R. H., Jun 1 2017, In : Brain Imaging and Behavior. 11, 3, p. 632-639 8 p.

    Research output: Contribution to journalArticle

  • 5 Scopus citations

    Vulnerability of white matter tracts and cognition to the SOD2 polymorphism: A preliminary study of antioxidant defense genes in brain aging

    Salminen, L. E., Schofield, P. R., Pierce, K. D., Bruce, S. E., Griffin, M. G., Tate, D. F., Cabeen, R. P., Laidlaw, D. H., Conturo, T. E., Bolzenius, J. D. & Paul, R. H., Jun 30 2017, In : Behavioural Brain Research. 329, p. 111-119 9 p.

    Research output: Contribution to journalArticle

  • 3 Scopus citations

    Neuromarkers of the common angiotensinogen polymorphism in healthy older adults: A comprehensive assessment of white matter integrity and cognition

    Salminen, L. E., Schofield, P. R., Pierce, K. D., Zhao, Y., Luo, X., Wang, Y., Laidlaw, D. H., Cabeen, R. P., Conturo, T. E., Tate, D. F., Akbudak, E., Lane, E. M., Heaps, J. M., Bolzenius, J. D., Baker, L. M., Cagle, L. M. & Paul, R. H., Jan 1 2016, In : Behavioural Brain Research. 296, p. 85-93 9 p.

    Research output: Contribution to journalArticle

  • 6 Scopus citations