• 10928 Citations

Research output per year

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Personal profile

Research interests

Dr. Benzinger's research focuses on translating advanced neuromagnetic resonance imaging techniques from small animal research in the department of radiology, to translational research in the Center for Clinical Imaging Research (CCIR), and into clinical practice. In particular, her current research focuses on using directional diffusivity measurements derived from diffusion tensor imaging (DTI) to measure axonal and myelin damage in pediatric and adult demyelination, dysmyelinating diseases, and as a function of aging. In addition, Dr. Benzinger combines advanced neuromagnetic resonance techniques, such as DTI and spectrosopy, and positron emission tomogrophy (PET) to study interactions between normal aging, Alzheimer's disease, depression and delerium in older adults.

Areas of Clinical Interest


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Research Output

Acute Rodent Tolerability, Toxicity, and Radiation Dosimetry Estimates of the S1P1-Specific Radioligand [11C]CS1P1

Liu, H., Laforest, R., Gu, J., Luo, Z., Jones, L. A., Gropler, R. J., Benzinger, T. L. S. & Tu, Z., Apr 1 2020, In : Molecular Imaging and Biology. 22, 2, p. 285-292 8 p.

Research output: Contribution to journalArticle

  • Amyloid and Tau Pathology Associations With Personality Traits, Neuropsychiatric Symptoms, and Cognitive Lifestyle in the Preclinical Phases of Sporadic and Autosomal Dominant Alzheimer's Disease

    Dominantly Inherited Alzheimer Network (DIAN) & PREVENT-AD Research Group, 2020, (Accepted/In press) In : Biological Psychiatry.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline

    Montagne, A., Nation, D. A., Sagare, A. P., Barisano, G., Sweeney, M. D., Chakhoyan, A., Pachicano, M., Joe, E., Nelson, A. R., D’Orazio, L. M., Buennagel, D. P., Harrington, M. G., Benzinger, T. L. S., Fagan, A. M., Ringman, J. M., Schneider, L. S., Morris, J. C., Reiman, E. M., Caselli, R. J., Chui, H. C. & 7 others, Tcw, J., Chen, Y., Pa, J., Conti, P. S., Law, M., Toga, A. W. & Zlokovic, B. V., May 7 2020, In : Nature. 581, 7806, p. 71-76 6 p.

    Research output: Contribution to journalArticle

  • 30 Scopus citations

    A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease

    the Dominantly Inherited Alzheimer Network, Mar 1 2020, In : Nature medicine. 26, 3, p. 398-407 10 p.

    Research output: Contribution to journalArticle

  • 18 Scopus citations

    Association of education with Aβ burden in preclinical familial and sporadic Alzheimer disease

    DIAN Study Group and the PREVENT-AD Research Group, Sep 15 2020, In : Neurology. 95, 11, p. e1554-e1564

    Research output: Contribution to journalArticle