Research output per year
Research output per year
- 19 results
Search results
-
2024
Etomoxir-carnitine, a novel pharmaco-metabolite of etomoxir, inhibits phospholipases A2 and mitochondrial respiration
Ho Moon, S., Liu, X., Jenkins, C. M., Dilthey, B. G., Patti, G. J. & Gross, R. W., Sep 2024, In: Journal of lipid research. 65, 9, 100611.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2023
Genetic deletion of skeletal muscle iPLA2γ results in mitochondrial dysfunction, muscle atrophy and alterations in whole-body energy metabolism
Moon, S. H., Dilthey, B. G., Guan, S., Sims, H. F., Pittman, S. K., Keith, A. L., Jenkins, C. M., Weihl, C. C. & Gross, R. W., Jun 16 2023, In: iScience. 26, 6, 106895.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
2021
High-fat diet activates liver iPLA2γ generating eicosanoids that mediate metabolic stress
Moon, S. H., Dilthey, B. G., Liu, X., Guan, S., Sims, H. F. & Gross, R. W., 2021, In: Journal of lipid research. 62, 100052.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
2020
A functional role for eicosanoid-lysophospholipids in activating monocyte signaling
Liu, G. Y., Moon, S. H., Jenkins, C. M., Sims, H. F., Guan, S. & Gross, R. W., Aug 21 2020, In: Journal of Biological Chemistry. 295, 34, p. 12167-12180 14 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
2019
Synthesis of oxidized phospholipids by sn-1 acyltransferase using 2–15-HETE lysophospholipids
Liu, G. Y., Moon, S. H., Jenkins, C. M., Sims, H. F., Guan, S. & Gross, R. W., Jun 28 2019, In: Journal of Biological Chemistry. 294, 26, p. 10146-10159 14 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
2018
Cytochrome c is an oxidative stress–activated plasmalogenase that cleaves plasmenylcholine and plasmenylethanolamine at the sn-1 vinyl ether linkage
Jenkins, C. M., Yang, K., Liu, G., Moon, S. H., Dilthey, B. G. & Gross, R. W., Jun 1 2018, In: Journal of Biological Chemistry. 293, 22, p. 8693-8709 17 p.Research output: Contribution to journal › Article › peer-review
Open Access58 Scopus citations -
Identifying off-target effects of etomoxir reveals that carnitine palmitoyltransferase i is essential for cancer cell proliferation independent of β-oxidation
Yao, C. H., Liu, G. Y., Wang, R., Moon, S. H., Gross, R. W. & Patti, G. J., 2018, In: PLoS biology. 16, 3, e2003782.Research output: Contribution to journal › Article › peer-review
Open Access154 Scopus citations -
2017
The phospholipase iPLA2 is a major mediator releasing oxidized aliphatic chains from cardiolipin, integrating mitochondrial bioenergetics and signaling
Liu, G. Y., Ho Moon, S., Jenkins, C. M., Li, M., Sims, H. F., Guan, S. & Gross, R. W., Jun 23 2017, In: Journal of Biological Chemistry. 292, 25, p. 10672-10684 13 p.Research output: Contribution to journal › Article › peer-review
Open Access74 Scopus citations -
2016
Cardiac myocyte-specific knock-out of calcium-independent phospholipase a2 γ (ipla2 γ) decreases oxidized fatty acids during ischemia/reperfusion and reduces infarct size
Moon, S. H., Mancuso, D. J., Sims, H. F., Liu, X., Nguyen, A. L., Yang, K., Guan, S., Dilthey, B. G., Jenkins, C. M., Weinheimer, C. J., Kovacs, A., Abendschein, D. & Gross, R. W., Sep 9 2016, In: Journal of Biological Chemistry. 291, 37, p. 19687-19700 14 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
Cyclooxygenase-2 Mediated Oxidation of 2-Arachidonoyl-Lysophospholipids Identifies Unknown Lipid Signaling Pathways
Liu, X., Moon, S. H., Jenkins, C. M., Sims, H. F. & Gross, R. W., Oct 20 2016, In: Cell Chemical Biology. 23, 10, p. 1217-1227 11 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
2015
Loss of function variants in human PNPLA8 encoding calcium-independent phospholipase A2γ recapitulate the mitochondriopathy of the homologous null mouse
Saunders, C. J., Moon, S. H., Liu, X., Thiffault, I., Coffman, K., Lepichon, J. B., Taboada, E., Smith, L. D., Farrow, E. G., Miller, N., Gibson, M., Patterson, M., Kingsmore, S. F. & Gross, R. W., Mar 1 2015, In: Human mutation. 36, 3, p. 301-306 6 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
2013
Oxidized fatty acid analysis by charge-switch derivatization, selected reaction monitoring, and accurate mass quantitation
Liu, X., Moon, S. H., Mancuso, D. J., Jenkins, C. M., Guan, S., Sims, H. F. & Gross, R. W., 2013, In: Analytical Biochemistry. 442, 1, p. 40-50 11 p.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
2012
Activation of mitochondrial calcium-independent phospholipase A 2γ (iPLA2γ) by divalent cations mediating arachidonate release and production of downstream eicosanoids
Moon, S. H., Jenkins, C. M., Liu, X., Guan, S., Mancuso, D. J. & Gross, R. W., Apr 27 2012, In: Journal of Biological Chemistry. 287, 18, p. 14880-14895 16 p.Research output: Contribution to journal › Article › peer-review
Open Access60 Scopus citations -
Genetic ablation of calcium-independent phospholipase A2γ (iPLA2γ) attenuates calcium-induced opening of the mitochondrial permeability transition pore and resultant cytochrome c release
Moon, S. H., Jenkins, C. M., Kiebish, M. A., Sims, H. F., Mancuso, D. J. & Gross, R. W., Aug 24 2012, In: Journal of Biological Chemistry. 287, 35, p. 29837-29850 14 p.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
2011
CD36 protein is involved in store-operated calcium flux, phospholipase A2 activation, and production of prostaglandin E2
Kuda, O., Jenkins, C. M., Skinner, J. R., Moon, S. H., Su, X., Gross, R. W. & Abumrad, N. A., May 20 2011, In: Journal of Biological Chemistry. 286, 20, p. 17785-17795 11 p.Research output: Contribution to journal › Article › peer-review
Open Access76 Scopus citations -
2010
Genetic ablation of calcium-independent phospholipase A2β causes hypercontractility and markedly attenuates endothelium-dependent relaxation to acetylcholine
Dietrich, H. H., Abendschein, D. R., Moon, S. H., Nayeb-Hashemi, N., Mancuso, D. J., Jenkins, C. M., Kaltenbronn, K. M., Blumer, K. J., Turk, J. & Gross, R. W., Jun 2010, In: American Journal of Physiology - Heart and Circulatory Physiology. 298, 6, p. H2208-H2220Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Genetic ablation of calcium-independent phospholipase A2γ prevents obesity and insulin resistance during high fat feeding by mitochondrial uncoupling and increased adipocyte fatty acid oxidation
Mancuso, D. J., Sims, H. F., Yang, K., Kiebish, M. A., Su, X., Jenkins, C. M., Guan, S., Moon, S. H., Pietka, T., Nassir, F., Schappe, T., Moore, K., Han, X., Abumrad, N. A. & Gross, R. W., Nov 19 2010, In: Journal of Biological Chemistry. 285, 47, p. 36495-36510 16 p.Research output: Contribution to journal › Article › peer-review
Open Access81 Scopus citations -
2008
Smooth muscle cell arachidonic acid release, migration, and proliferation are markedly attenuated in mice null for calcium-independent phospholipase A2β
Sung, H. M., Jenkins, C. M., Mancuso, D. J., Turk, J. & Gross, R. W., Dec 5 2008, In: Journal of Biological Chemistry. 283, 49, p. 33975-33987 13 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
2007
Genetic ablation of calcium-independent phospholipase A2γ leads to alterations in mitochondrial lipid metabolism and function resulting in a deficient mitochondrial bioenergetic phenotype
Mancuso, D. J., Sims, H. F., Han, X., Jenkins, C. M., Shao, P. G., Yang, K., Sung, H. M., Pietka, T., Abumrad, N. A., Schlesinger, P. H. & Gross, R. W., Nov 30 2007, In: Journal of Biological Chemistry. 282, 48, p. 34611-34622 12 p.Research output: Contribution to journal › Article › peer-review
Open Access137 Scopus citations