Steven Brody

Dorothy R and Hubert C Moog Professor of Pulmonary Diseases in Medicine, Professor of Radiology

    • 7117 Citations
    1973 …2020

    Research output per year

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    Personal profile

    Research interests

    Our research focus is abnormalities of the airway epithelial cell differentiation that characterize lung diseases such as bronchitis, bronchiectasis, respiratory virus and bacterial infection. We are particularly interested in mechanisms of ciliated cell differentiation and cilia biogenesis. These studies are linked to investigation of the genetic basis of lung disease in patient populations with known or suspected defects in cilia, co-called ciliopathies.

    Areas of Clinical Interest

    Critical care medicine, ARDS, septic shock, clinical toxicology, cystic fibrosis, primary ciliary dyskinesia

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    Research Output

    Efficient Generation and Transcriptomic Profiling of Human iPSC-Derived Pulmonary Neuroendocrine Cells

    Hor, P., Punj, V., Calvert, B. A., Castaldi, A., Miller, A. J., Carraro, G., Stripp, B. R., Brody, S. L., Spence, J. R., Ichida, J. K., Ryan (Firth), A. L. & Borok, Z., May 22 2020, In : iScience. 23, 5, 101083.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations

    Preterm intraventricular hemorrhage in vitro: Modeling the cytopathology of the ventricular zone

    Castaneyra-Ruiz, L., McAllister, J. P., Morales, D. M., Brody, S. L., Isaacs, A. M. & Limbrick, D. D., Jul 20 2020, In : Fluids and barriers of the CNS. 17, 1, 46.

    Research output: Contribution to journalArticle

    Open Access
  • An obligatory role for club cells in preventing obliterative bronchiolitis in lung transplants

    Liu, Z., Liao, F., Scozzi, D., Furuya, Y., Pugh, K. N., Hachem, R., Chen, D. L., Cano, M., Green, J. M., Krupnick, A. S., Kreisel, D., Perl, A. K. T., Huang, H. J., Brody, S. L. & Gelman, A. E., 2019, In : JCI Insight. 4, 9, e124732.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations

    Autophagy proteins are required for club cell structure and function in airways

    Malvin, N. P., Kern, J. T., Liu, T. C., Brody, S. L. & Stappenbeck, T. S., Aug 2019, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 317, 2, p. L259-L270

    Research output: Contribution to journalArticle

  • 2 Scopus citations