Research output per year
Research output per year
Personal profile
Research interests
I am the pediatric radiation oncologist for Siteman Cancer Center and my research involves the treatment of childhood malignancies, as well as the late effects of therapy. My lab focuses on the neurocognitive outcomes of pediatric brain tumor patients. This research includes an ongoing prospective analysis of resting-state functional connectivity MRI (RSFC MRI) as a potential biomarker for cognitive outcome.
Clinical interests
I am a board-certified radiation oncologist with a special focus on pediatric oncology and neuro-oncology. I hold the S. Lee Kling Chair in Radiation Oncology at Washington University School of Medicine in St. Louis, Missouri. I serve as the director of the S. Lee Kling Proton Therapy Center and chief of the Pediatric Radiotherapy Service. My clinical interests include proton therapy, pediatric brain tumors, stereotactic radiosurgery, pediatric cancer-focused radiopharmaceuticals, and the management of brain arteriovenous malformations.
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Collaborations and top research areas from the last five years
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Dosimetric evaluation of dose shaping by adaptive aperture and its impact on plan quality
Silvus, A., Haefner, J., Altman, M. B., Zhao, T., Perkins, S. & Zhang, T., Mar 1 2024, In: Medical Dosimetry. 49, 1, p. 30-36 7 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Functional network disorganization and cognitive decline following fractionated whole-brain radiation in mice
Seitzman, B. A., Reynoso, F. J., Mitchell, T. J., Bice, A. R., Jarang, A., Wang, X., Mpoy, C., Strong, L., Rogers, B. E., Yuede, C. M., Rubin, J. B., Perkins, S. M. & Bauer, A. Q., Feb 2024, In: GeroScience. 46, 1, p. 543-562 20 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
High spatiotemporal resolution scintillation imaging of pulsed pencil beam scanning proton beams produced by a gantry-mounted synchrocyclotron
Goddu, S. M., Hao, Y., Ji, Z., Setianegara, J., Liu, F., Green, W., Sobotka, L. G., Zhao, T., Perkins, S. & Darafsheh, A., Jul 2024, In: Medical physics. 51, 7, p. 4996-5006 11 p.Research output: Contribution to journal › Article › peer-review
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Risk factors for neurocognitive impairment, emotional distress, and poor quality of life in survivors of pediatric rhabdomyosarcoma: A report from the Childhood Cancer Survivor Study
van der Plas, E., Darji, H., Srivastava, D. K., Schapiro, M., Jeffe, D., Perkins, S., Howell, R., Leisenring, W., Armstrong, G. T., Oeffinger, K., Krull, K., Edelstein, K. & Hayashi, R. J., Jun 15 2024, In: Cancer. 130, 12, p. 2224-2236 13 p.Research output: Contribution to journal › Article › peer-review
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An Analysis of Major Target Deviations in Craniospinal Irradiation Treatment Plans for Patients With Intermediate-Risk Medulloblastoma Within a Phase 3 Clinical Trial (Children's Oncology Group Study ACNS0331)
Schiff, J. P., Lee, Y., Wang, Y., Perkins, S. M., Kessel, S. K., Fitzgerald, T. J., Larrier, N. A. & Michalski, J. M., Jan 1 2023, In: Advances in Radiation Oncology. 8, 1, 101083.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations