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Personal profile

Research interests

With the overall theme of understanding the biological regulation of skeletal matrix quality, our research group integrates engineering and biology approaches for (1) understanding the effect of disease mechanisms on the structure-function relationships of skeletal tissues and (2) developing of translatable therapeutic and regenerative strategies for these diseases. The investigation of these scientific questions includes the application of finite element analyses, multiscale tissue mechanics, the functional imaging of skeletal tissues, and development of nanostructures and nanomaterials for regenerative medicine with in vitro and in vivo biological systems.

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Research Output

Determination of the Depth- and Time- Dependent Mechanical Behavior of Mouse Articular Cartilage Using Cyclic Reference Point Indentation

Chang, A. & Tang, S. Y., Jul 1 2020, In : Cartilage. 11, 3, p. 358-363 6 p.

Research output: Contribution to journalArticle

  • 2 Scopus citations

    Rapid determination of internal strains in soft tissues using an experimentally calibrated finite element model derived from magnetic resonance imaging

    Yoon, D. H. E., Weber, C. I., Easson, G. W. D., Broz, K. S. & Tang, S. Y., Jan 1 2020, In : Quantitative Imaging in Medicine and Surgery. 10, 1, p. 57-65 9 p.

    Research output: Contribution to journalArticle

  • Sclerostin Regulation, Microarchitecture, and Advanced Glycation End-Products in the Bone of Elderly Women With Type 2 Diabetes

    Piccoli, A., Cannata, F., Strollo, R., Pedone, C., Leanza, G., Russo, F., Greto, V., Isgrò, C., Quattrocchi, C. C., Massaroni, C., Silvestri, S., Vadalà, G., Bisogno, T., Denaro, V., Pozzilli, P., Tang, S. Y., Silva, M., Conte, C., Papalia, R., Maccarrone, M. & 1 others, Napoli, N., 2020, (Accepted/In press) In : Journal of Bone and Mineral Research.

    Research output: Contribution to journalArticle

  • Behavioral Compensations and Neuronal Remodeling in a Rodent Model of Chronic Intervertebral Disc Degeneration

    Leimer, E. M., Gayoso, M. G., Jing, L., Tang, S. Y., Gupta, M. C. & Setton, L. A., Dec 1 2019, In : Scientific reports. 9, 1, 3759.

    Research output: Contribution to journalArticle

    Open Access
  • 4 Scopus citations

    Cannulated Screw Prominence in Tension Band Wiring of Patella Fractures Increases Fracture Gapping: A Cadaver Study

    Avery, M. C., Jo, S., Chang, A., Ricci, W. M., McAndrew, C., Miller, A. N. & Tang, S., May 1 2019, In : Clinical orthopaedics and related research. 477, 5, p. 1249-1255 7 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations