Research Output per year
Research Output per year
Personal profile
Research interests
My lab's major interest is to understand the systemic regulatory network for the control of aging and longevity in mammals, focusing on the roles of NAD-dependent mammalian sirtuins and NAD biosynthesis pathways. We are also trying to translate our findings to humans and develop preventive/therapeutic anti-aging interventions.
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Research Output
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Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men
Irie, J., Inagaki, E., Fujita, M., Nakaya, H., Mitsuishi, M., Yamaguchi, S., Yamashita, K., Shigaki, S., Ono, T., Yukioka, H., Okano, H., Nabeshima, Y. I., Imai, S. I., Yasui, M., Tsubota, K. & Itoh, H., 2020, In: Endocrine Journal. 67, 2, p. 153-160 8 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
SS-31 and NMN: Two paths to improve metabolism and function in aged hearts
Whitson, J. A., Bitto, A., Zhang, H., Sweetwyne, M. T., Coig, R., Bhayana, S., Shankland, E. G., Wang, L., Bammler, T. K., Mills, K. F., Imai, S. I., Conley, K. E., Marcinek, D. J. & Rabinovitch, P. S., Oct 1 2020, In: Aging Cell. 19, 10, e13213.Research output: Contribution to journal › Article › peer-review
Open Access -
Author Correction: Slc12a8 is a nicotinamide mononucleotide transporter (Nature Metabolism, (2019), 1, 1, (47-57), 10.1038/s42255-018-0009-4)
Grozio, A., Mills, K. F., Yoshino, J., Bruzzone, S., Sociali, G., Tokizane, K., Lei, H. C., Cunningham, R., Sasaki, Y., Migaud, M. E. & Imai, S. I., Jul 1 2019, In: Nature Metabolism. 1, 7, p. 743 1 p.Research output: Contribution to journal › Comment/debate
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Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice
Yoshida, M., Satoh, A., Lin, J. B., Mills, K. F., Sasaki, Y., Rensing, N., Wong, M., Apte, R. S. & Imai, S. I., Aug 6 2019, In: Cell metabolism. 30, 2, p. 329-342.e5Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
Reply to: Absence of evidence that Slc12a8 encodes a nicotinamide mononucleotide transporter
Grozio, A., Mills, K., Yoshino, J., Bruzzone, S., Sociali, G., Tokizane, K., Lei, H. C., Sasaki, Y., Migaud, M. & Imai, S. I., Jul 1 2019, In: Nature Metabolism. 1, 7, p. 662-665 4 p.Research output: Contribution to journal › Letter › peer-review
Open Access1 Scopus citations