Research output per year
Research output per year
Personal profile
Research interests
My lab's major interest is to understand the systemic regulatory network for the control of aging and longevity in mammals, focusing on the roles of NAD-dependent mammalian sirtuins and NAD biosynthesis pathways. We are also trying to translate our findings to humans and develop preventive/therapeutic anti-aging interventions.
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SIRT1 mediates hypoxic postconditioning- and resveratrol-induced protection against functional connectivity deficits after subarachnoid hemorrhage
Clarke, J. V., Brier, L. M., Rahn, R. M., Diwan, D., Yuan, J. Y., Bice, A. R., Imai, S. I., Vellimana, A. K., Culver, J. P. & Zipfel, G. J., Jul 2022, In: Journal of Cerebral Blood Flow and Metabolism. 42, 7, p. 1210-1223 14 p.Research output: Contribution to journal › Article › peer-review
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Friends and foes: Extracellular vesicles in aging and rejuvenation
Lananna, B. V. & Imai, S. I., Oct 2021, In: FASEB BioAdvances. 3, 10, p. 787-801 15 p.Research output: Contribution to journal › Review article › peer-review
Open Access3 Scopus citations -
Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women
Yoshino, M., Yoshino, J., Kayser, B. D., Patti, G. J., Franczyk, M. P., Mills, K. F., Sindelar, M., Pietka, T., Patterson, B. W., Imai, S. I. & Klein, S., Jun 11 2021, In: Science. 372, 6547, p. 1224-1229 6 p.Research output: Contribution to journal › Article › peer-review
46 Scopus citations -
The 2021 FASEB science research conference on NAD metabolism and signaling
Gorbunova, V., Buschbeck, M., Cambronne, X. A., Chellappa, K., Corda, D., Du, J., Freichel, M., Gigas, J., Green, A. E., Gu, F., Guberovic, I., Jayabalan, A., Khansahib, I., Mukherjee, S., Seluanov, A., Simon, M. A., Sverkeli, L. J., Kory, N., Levine, D. C., Matic, I. & 9 others, , 2021, In: Aging. 13, 23, p. 24924-24930 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men
Irie, J., Inagaki, E., Fujita, M., Nakaya, H., Mitsuishi, M., Yamaguchi, S., Yamashita, K., Shigaki, S., Ono, T., Yukioka, H., Okano, H., Nabeshima, Y. I., Imai, S. I., Yasui, M., Tsubota, K. & Itoh, H., 2020, In: Endocrine Journal. 67, 2, p. 153-160 8 p.Research output: Contribution to journal › Article › peer-review
Open Access55 Scopus citations