Research output per year
Research output per year
Personal profile
Research interests
My lab's major interest is to understand the systemic regulatory network for the control of aging and longevity in mammals, focusing on the roles of NAD-dependent mammalian sirtuins and NAD biosynthesis pathways. We are also trying to translate our findings to humans and develop preventive/therapeutic anti-aging interventions.
Available to Mentor:
- PhD/MSTP Students
Fingerprint
Dive into the research topics where Shin-Ichiro Imai is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Effects of nicotinamide mononucleotide on older patients with diabetes and impaired physical performance: A prospective, placebo-controlled, double-blind study
Akasaka, H., Nakagami, H., Sugimoto, K., Yasunobe, Y., Minami, T., Fujimoto, T., Yamamoto, K., Hara, C., Shiraki, A., Nishida, K., Asano, K., Kanou, M., Yamana, K., Imai, S. I. & Rakugi, H., Jan 2023, In: Geriatrics and Gerontology International. 23, 1, p. 38-43 6 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Sleep–wake patterns are altered with age, Prdm13 signaling in the DMH, and diet restriction in mice
Tsuji, S., Brace, C. S., Yao, R., Tanie, Y., Tada, H., Rensing, N., Mizuno, S., Almunia, J., Kong, Y., Nakamura, K., Furukawa, T., Ogiso, N., Toyokuni, S., Takahashi, S., Wong, M., Imai, S. I. & Satoh, A., Jun 2023, In: Life Science Alliance. 6, 6, e202301992.Research output: Contribution to journal › Article › peer-review
Open Access -
Age-related disruption of the proteome and acetylome in mouse hearts is associated with loss of function and attenuated by elamipretide (SS-31) and nicotinamide mononucleotide (NMN) treatment
Whitson, J. A., Johnson, R., Wang, L., Bammler, T. K., Imai, S. I., Zhang, H., Fredrickson, J., Latorre-Esteves, E., Bitto, A., MacCoss, M. J. & Rabinovitch, P. S., Jun 2022, In: GeroScience. 44, 3, p. 1621-1639 19 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health
Stanford TDA, University of Connecticut TMC, University of Michigan TDA, University of Minnesota TMC, University of Pittsburgh TMC, University of Washington TDA, Washington University TMC, Yale TMC, SenNet Consortium, Writing Group, Brown University TDA, Buck Institute for Research on Aging TMC/TDA, Consortium Organization and Data Coordinating Center (CODCC), Columbia TMC, Duke University TMC, Massachusetts General Hospital TDA, Mayo Clinic TDA & National Institute of Health (NIH), Dec 2022, In: Nature Aging. 2, 12, p. 1090-1100 11 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
SIRT1 mediates hypoxic postconditioning- and resveratrol-induced protection against functional connectivity deficits after subarachnoid hemorrhage
Clarke, J. V., Brier, L. M., Rahn, R. M., Diwan, D., Yuan, J. Y., Bice, A. R., Imai, S. I., Vellimana, A. K., Culver, J. P. & Zipfel, G. J., Jul 2022, In: Journal of Cerebral Blood Flow and Metabolism. 42, 7, p. 1210-1223 14 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations