Research output per year
Research output per year
Personal profile
Research interests
My lab's major interest is to understand the systemic regulatory network for the control of aging and longevity in mammals, focusing on the roles of NAD-dependent mammalian sirtuins and NAD biosynthesis pathways. We are also trying to translate our findings to humans and develop preventive/therapeutic anti-aging interventions.
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Friends and foes: Extracellular vesicles in aging and rejuvenation
Lananna, B. V. & Imai, S. I., Oct 2021, In: FASEB BioAdvances. 3, 10, p. 787-801 15 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women
Yoshino, M., Yoshino, J., Kayser, B. D., Patti, G. J., Franczyk, M. P., Mills, K. F., Sindelar, M., Pietka, T., Patterson, B. W., Imai, S. I. & Klein, S., Jun 11 2021, In: Science. 372, 6547, p. 1224-1229 6 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men
Irie, J., Inagaki, E., Fujita, M., Nakaya, H., Mitsuishi, M., Yamaguchi, S., Yamashita, K., Shigaki, S., Ono, T., Yukioka, H., Okano, H., Nabeshima, Y. I., Imai, S. I., Yasui, M., Tsubota, K. & Itoh, H., 2020, In: Endocrine Journal. 67, 2, p. 153-160 8 p.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations -
SS-31 and NMN: Two paths to improve metabolism and function in aged hearts
Whitson, J. A., Bitto, A., Zhang, H., Sweetwyne, M. T., Coig, R., Bhayana, S., Shankland, E. G., Wang, L., Bammler, T. K., Mills, K. F., Imai, S. I., Conley, K. E., Marcinek, D. J. & Rabinovitch, P. S., Oct 1 2020, In: Aging Cell. 19, 10, e13213.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Author Correction: Slc12a8 is a nicotinamide mononucleotide transporter (Nature Metabolism, (2019), 1, 1, (47-57), 10.1038/s42255-018-0009-4)
Grozio, A., Mills, K. F., Yoshino, J., Bruzzone, S., Sociali, G., Tokizane, K., Lei, H. C., Cunningham, R., Sasaki, Y., Migaud, M. E. & Imai, S. I., Jul 1 2019, In: Nature Metabolism. 1, 7, p. 743 1 p.Research output: Contribution to journal › Comment/debate