Sharon Morley

Associate Professor of Pediatrics, Associate Professor of Pathology and Immunology

    • 527 Citations

    Research output per year

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    Personal profile

    Research interests

    Regulation of adaptive and innate immunity by actin-binding proteins, currently focusing on the role of the bundling protein L-plastin. Mice deficient for L-plastin exhibit defects in T and B cell chemotaxis and activation due to failures of cellular polarization and maintenance of cell contacts. I am also developing a research interested into pulmonary immunity and the immune response in pneumococcal pneumonia.

    Areas of Clinical Interest

    Pediatric infections

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    Research Output

    • 527 Citations
    • 25 Article
    • 3 Review article
    • 1 Comment/debate
    • 1 Short survey

    L-Plastin deficiency produces increased trabecular bone due to attenuation of sealing ring formation and osteoclast dysfunction

    Chellaiah, M. A., Moorer, M. C., Majumdar, S., Aljohani, H., Morley, S. C., Yingling, V. & Stains, J. P., Dec 1 2020, In : Bone Research. 8, 1, 3.

    Research output: Contribution to journalArticle

    Open Access
  • 3 Scopus citations

    Neutrophil L-Plastin Controls Ocular Paucibacteriality and Susceptibility to Keratitis

    Lu, X., Kugadas, A., Smith-Page, K., Lamb, J., Lin, T., Ru, Y., Morley, S. C., Fichorova, R., Mittal, S. K., Chauhan, S. K., Littleton, S., Saban, D. & Gadjeva, M., Apr 3 2020, In : Frontiers in immunology. 11, 547.

    Research output: Contribution to journalArticle

    Open Access
  • The association of medications and vaccination with risk of pneumonia in inflammatory bowel disease

    Gregory, M. H., Ciorba, M. A., Wiitala, W. L., Stidham, R. W., Higgins, P., Celeste Morley, S., Hou, J. K., Feagins, L. A., Govani, S. M., Cohen-Mekelburg, S. A. & Waljee, A. K., 2020, In : Inflammatory bowel diseases. 26, 6, p. 919-925 7 p.

    Research output: Contribution to journalArticle

  • 2 Scopus citations

    Cells under stress: The mechanical environment shapes inflammasome responses to danger signals

    Joshi, H. & Morley, S. C., Jul 2019, In : Journal of Leukocyte Biology. 106, 1, p. 119-125 7 p.

    Research output: Contribution to journalReview article

  • 3 Scopus citations

    Inhaled GM-CSF in neonatal mice provides durable protection against bacterial pneumonia

    Todd, E. M., Ramani, R., Szasz, T. P. & Celeste Morley, S., Aug 14 2019, In : Science Advances. 5, 8, eaax3387.

    Research output: Contribution to journalArticle

    Open Access
  • 3 Scopus citations