Research Output per year
Research Output per year
Personal profile
Research interests
My laboratory is engaged in translational research focused on investigating genetic and pharmacogenetic associations with cardiovascular disease, with a particular interest in diabetic cardiovascular disease. Ongoing projects in my laboratory include 1) comprehensively investigating the genetic and pharmacogenetic associations of PPAR-pathway variants, using a custom PPAR-pathway targeted-genotyping 3K array, in a population with type 2 DM and coronary artery disease that has been extensively phenotyped (BARI 2D cohort); 2) assessing the predictive impact of genetic variants in the context of modern post-ACS therapy in a cohort of 4,500 patients with acute myocardial infarction (TRIUMPH cohort).
Areas of Clinical Interest
Transthoracic, transesophageal and stress echocardiograms
Keywords
- COVID-19
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Research Output
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Association of factor v leiden with subsequent atherothrombotic events: A GENIUS-CHD study of individual participant data
Mahmoodi, B. K., Tragante, V., Kleber, M. E., Holmes, M. V., Schmidt, A. F., McCubrey, R. O., Howe, L. J., Direk, K., Allayee, H., Baranova, E. V., Braund, P. S., Delgado, G. E., Eriksson, N., Gijsberts, C. M., Gong, Y., Hartiala, J., Heydarpour, M., Pasterkamp, G., Kotti, S., Kuukasjärvi, P. & 64 others, , Aug 11 2020, In: Circulation. 142, 6, p. 546-555 10 p.Research output: Contribution to journal › Article › peer-review
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Genetic architecture of circulating very-long-chain (C24:0 and c22:0) ceramide concentrations
Cresci, S., Zhang, R., Yang, Q., Duncan, M. S., Xanthakis, V., Jiang, X., Vasan, R. S., Schaffer, J. & Peterson, L., Jan 1 2020, In: Journal of Lipid and Atherosclerosis. 9, 1, p. 172-183 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
PPARA polymorphism influences the cardiovascular benefit of fenofibrate in type 2 diabetes: Findings from accord-lipid
Morieri, M. L., Shah, H. S., Sjaarda, J., Lenzini, P. A., Campbell, H., Motsinger-Reif, A. A., Gao, H., Lovato, L., Prudente, S., Pandolfi, A., Pezzolesi, M. G., Sigal, R. J., Paré, G., Marcovina, S. M., Rotroff, D. M., Patorno, E., Mercuri, L., Trischitta, V., Chew, E. Y., Kraft, P. & 7 others, , Apr 1 2020, In: Diabetes. 69, 4, p. 771-783 13 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
A genetic locus on chromosome 2q24 predicting peripheral neuropathy risk in type 2 diabetes: Results from the ACCORD and BARI 2D studies
Tang, Y., Lenzini, P. A., Pop-Busui, R., Ray, P. R., Campbell, H., Perkins, B. A., Callaghan, B., Wagner, M. J., Motsinger-Reif, A. A., Buse, J. B., Price, T. J., Mychaleckyj, J. C., Cresci, S., Shah, H. & Doria, A., Aug 1 2019, In: Diabetes. 68, 8, p. 1649-1662 14 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Association of chromosome 9p21 with subsequent coronary heart disease events: A GENIUS-CHD study of individual participant data
CARDIoGRAMPlusC4D Consortium, 2019, In: Circulation: Genomic and Precision Medicine. 12, 4, p. 161-172 12 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations