Research output per year
Research output per year
Personal profile
Research interests
My laboratory is engaged in translational research focused on investigating genetic and pharmacogenetic associations with cardiovascular disease, with a particular interest in diabetic cardiovascular disease. Ongoing projects in my laboratory include 1) comprehensively investigating the genetic and pharmacogenetic associations of PPAR-pathway variants, using a custom PPAR-pathway targeted-genotyping 3K array, in a population with type 2 DM and coronary artery disease that has been extensively phenotyped (BARI 2D cohort); 2) assessing the predictive impact of genetic variants in the context of modern post-ACS therapy in a cohort of 4,500 patients with acute myocardial infarction (TRIUMPH cohort).
Clinical interests
Transthoracic, transesophageal and stress echocardiograms, hypertrophic cardiomyopathy.
Keywords
- COVID-19
Available to Mentor:
- PhD/MSTP Students
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Collaborations and top research areas from the last five years
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Association Between age or Duration of Diagnosis in Obstructive Hypertrophic Cardiomyopathy and Response to Mavacamten Treatment: Exploratory Analysis of the EXPLORER-HCM Trial
WANG, A., LAKDAWALA, N. K., ABRAHAM, T. P., NILLES, E. K., WOJDYLA, D. M., OWENS, A. T., BACH, R. G., SABERI, S. A. R. A., SEHNERT, A. M. Y. & CRESCI, S., 2025, (Accepted/In press) In: Journal of cardiac failure.Research output: Contribution to journal › Article › peer-review
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Association of Echocardiographic Parameters and Health Status in Patients With Obstructive Hypertrophic Cardiomyopathy: Insights From EXPLORER-HCM
Arnold, S. V., Gosch, K. L., Dolan, C., Fine, J. T., Masri, A., Saberi, S., Wang, A., Elliott, P. M., Hegde, S. M., Lam, J., Sehnert, A. J., Cresci, S., Bach, R. G. & Spertus, J. A., Nov 5 2024, In: Circulation. 150, 19, p. 1560-1562 3 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
CYP2C19 Genetic Testing for Oral P2Y12 Inhibitor Therapy: A Scientific Statement From the American Heart Association
on behalf of the American Heart Association Professional/Public Education and Publications Committee of the Council on Genomic and Precision Medicine; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; Council on Peripheral Vascular Disease; and Stroke Council, Aug 6 2024, In: Circulation. 150, 6, p. e129-e150Research output: Contribution to journal › Review article › peer-review
20 Scopus citations -
Effect of Mavacamten in Women Compared with Men with Obstructive Hypertrophic Cardiomyopathy: Insights from EXPLORER-HCM
Cresci, S., Bach, R. G., Saberi, S., Owens, A. T., Spertus, J. A., Hegde, S. M., Lakdawala, N. K., Nilles, E. K., Wojdyla, D. M., Sehnert, A. J. & Wang, A., Feb 13 2024, In: Circulation. 149, 7, p. 498-509 12 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Exercise Testing to Unmask Latent LVOT Obstruction in a Highly Symptomatic Patient With Hypertrophic Cardiomyopathy
Husaini, M., Bach, R. G. & Cresci, S., Aug 6 2024, In: Journal of the American College of Cardiology. 84, 6, p. 602-606 5 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations