Sessions Cole

Park J White, M.D. Professor of Pediatrics, Professor of Cell Biology and Physiology, Assistant Vice Chancellor for Children's Health, Washington University School of Medicine, Executive Vice Chair of the Department of Pediatrics

    • 5007 Citations
    1976 …2020

    Research output per year

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    Personal profile

    Research interests

    Genetic regulation of neonatal pulmonary surfactant deficiency has been suggested by studies of gender, genetic linkage, recurrent familial cases, targeted gene ablation in murine lineages, and by racial disparity in risk of neonatal respiratory distress syndrome. Successful fetal-neonatal pulmonary transition requires production of the pulmonary surfactant, a phospholipid-protein film that lines alveoli and maintains alveolar patency at end expiration. Our goal is to understand the genetic mechanisms that disrupt pulmonary surfactant metabolism and cause neonatal respiratory distress syndrome.

    Areas of Clinical Interest

    Inherited lung diseases of infancy, surfactant protein-B deficiency, newborn immunity, newborn infections, complement biosynthesis

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    Research Output

    Acute Kidney Injury and Bronchopulmonary Dysplasia in Premature Neonates Born Less than 32 Weeks' Gestation

    Starr, M. C., Boohaker, L., Eldredge, L. C., Menon, S., Griffin, R., Mayock, D. E., Li, L., Askenazi, D., Hingorani, S., Ambalavanan, N., Selewski, D. T., Sarkar, S., Kent, A., Fletcher, J., Abitbol, C. L., Defreitas, M., Duara, S., Charlton, J. R., Swanson, J. R., Guillet, R. & 52 others, D'Angio, C., Mian, A., Rademacher, E., Mhanna, M. J., Raina, R., Kumar, D., Jetton, J. G., Brophy, P. D., Colaizy, T. T., Klein, J. M., Arikan, A. A., Rhee, C. J., Goldstein, S. L., Nathan, A. T., Kupferman, J. C., Bhutada, A., Rastogi, S., Bonachea, E., Mahan, J., Cole, F. S., Davis, T. K., Dower, J., Milner, L., Smith, A., Fuloria, M., Reidy, K., Kaskel, F. J., Soranno, D. E., Gien, J., Gist, K. M., Chishti, A. S., Hanna, M. H., Wong, C. S., Joseph, C., Dupont, T., Ohls, R., Staples, A., Khokhar, S., Perazzo, S., Ray, P. E., Revenis, M., Sethi, S. K., Rohatgi, S., Mammen, C., Synnes, A., Wazir, S., Wintermark, P., Woroniecki, R., Sridhar, S., Ingraham, S., Nada, A. & Zappitelli, M., Feb 1 2020, In : American journal of perinatology. 37, 3, p. 341-348 8 p.

    Research output: Contribution to journalArticle

  • 3 Scopus citations

    Addressing medically underserved populations through maternal-fetal transport: a geographic analysis

    Rosenbloom, J. I., Nelson, D. M., Saunders, S., Cole, F. S., Chandarlis, J., Macones, G. A. & Cahill, A. G., Sep 1 2020, In : Journal of Maternal-Fetal and Neonatal Medicine. 33, 17, p. 2913-2917 5 p.

    Research output: Contribution to journalArticle

  • De novo EIF2AK1 and EIF2AK2 Variants Are Associated with Developmental Delay, Leukoencephalopathy, and Neurologic Decompensation

    Undiagnosed Diseases Network, Apr 2 2020, In : American journal of human genetics. 106, 4, p. 570-583 14 p.

    Research output: Contribution to journalArticle

  • Low hemoglobin levels are independently associated with neonatal acute kidney injury: a report from the AWAKEN Study Group

    AWAKEN Study Group, 2020, (Accepted/In press) In : Pediatric research.

    Research output: Contribution to journalArticle

  • Phenotypic expansion of KMT2D-related disorder: Beyond Kabuki syndrome

    Baldridge, D., Spillmann, R. C., Wegner, D. J., Wambach, J. A., White, F. V., Sisco, K., Toler, T. L., Dickson, P. I., Cole, F. S., Shashi, V. & Grange, D. K., May 1 2020, In : American Journal of Medical Genetics, Part A. 182, 5, p. 1053-1065 13 p.

    Research output: Contribution to journalArticle