Personal profile

Research interests

We have recently discovered that HIV-1 Integrase protein regulates particle maturation, a role completely independent of its catalytic activity. This involves the binding of integrase to viral RNA molecules, which ensures the encapsidation of viral RNA and IN in the viral core. Remarkably, integrase-RNA interactions can be targeted by a novel class of compounds that are currently in clinical trials. Our goal is to discover novel compounds that directly target integrase-RNA interactions and determine their mechanism of action, which will be of great value in the clinical setting.

Available to Mentor:

  • PhD/MSTP Students


Dive into the research topics where Sebla Kutluay is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 1 Similar Profiles

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or