Sean Whelan

Marvin A Brennecke Distinguished Professor of Molecular Microbiology, Head of the Department of Molecular Microbiology

    • 7397 Citations
    1994 …2020

    Research output per year

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    Keywords

    • COVID-19

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    Research Output

    A broad-spectrum antiviral molecule, QL47, selectively inhibits eukaryotic translation

    De Wispelaere, M., Carocci, M., Burri, D. J., Neidermyer, W. J., Olson, C. M., Roggenbach, I., Liang, Y., Wang, J., Whelan, S. P. J., Gray, N. S. & Yang, P. L., Jan 1 2020, In : Journal of Biological Chemistry. 295, 6, p. 1694-1703 10 p.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations

    Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2

    Kang, Y. L., Chou, Y. Y., Rothlauf, P. W., Liu, Z., Soh, T. K., Cureton, D., Case, J. B., Chen, R. E., Diamond, M. S., Whelan, S. P. J. & Kirchhausen, T., Aug 25 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 34, p. 20803-20813 11 p.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations

    Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2

    Case, J. B., Rothlauf, P. W., Chen, R. E., Liu, Z., Zhao, H., Kim, A. S., Bloyet, L. M., Zeng, Q., Tahan, S., Droit, L., Ilagan, M. X. G., Tartell, M. A., Amarasinghe, G., Henderson, J. P., Miersch, S., Ustav, M., Sidhu, S., Virgin, H. W., Wang, D., Ding, S. & 5 others, Corti, D., Theel, E. S., Fremont, D. H., Diamond, M. S. & Whelan, S. P. J., Sep 9 2020, In : Cell Host and Microbe. 28, 3, p. 475-485.e5

    Research output: Contribution to journalArticle

    Open Access
  • 7 Scopus citations

    Oligomerization of the Vesicular Stomatitis Virus Phosphoprotein Is Dispensable for mRNA Synthesis but Facilitates RNA Replication

    Bloyet, L. M., Morin, B., Brusic, V., Gardner, E., Ross, R. A., Vadakkan, T., Kirchhausen, T. & Whelan, S. P. J., Jun 16 2020, In : Journal of virology. 94, 13

    Research output: Contribution to journalArticle

    Open Access
  • Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein

    Zost, S. J., Gilchuk, P., Chen, R. E., Case, J. B., Reidy, J. X., Trivette, A., Nargi, R. S., Sutton, R. E., Suryadevara, N., Chen, E. C., Binshtein, E., Shrihari, S., Ostrowski, M., Chu, H. Y., Didier, J. E., MacRenaris, K. W., Jones, T., Day, S., Myers, L., Eun-Hyung Lee, F. & 11 others, Nguyen, D. C., Sanz, I., Martinez, D. R., Rothlauf, P. W., Bloyet, L. M., Whelan, S. P. J., Baric, R. S., Thackray, L. B., Diamond, M. S., Carnahan, R. H. & Crowe, J. E., Sep 1 2020, In : Nature medicine. 26, 9, p. 1422-1427 6 p.

    Research output: Contribution to journalArticle

    Open Access
  • 10 Scopus citations