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Personal profile

Research interests

I am interested in how the microbiome, including all of the bacteria, viruses and fungi that live in and on us contribute to health and disease. I have a particular focus on the microbiome in HIV and IBD.

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Research Output

  • 2275 Citations
  • 38 Article
  • 1 Letter
  • 1 Short survey
  • 1 Review article

An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis

Kim, A. S., Zimmerman, O., Fox, J. M., Nelson, C. A., Basore, K., Zhang, R., Durnell, L., Desai, C., Bullock, C., Deem, S. L., Oppenheimer, J., Shapiro, B., Wang, T., Cherry, S., Coyne, C. B., Handley, S. A., Landis, M. J., Fremont, D. H. & Diamond, M. S., Mar 11 2020, In : Cell Host and Microbe. 27, 3, p. 428-440.e9

Research output: Contribution to journalArticle

  • 1 Scopus citations
    Open Access
  • Select autophagy genes maintain quiescence of tissue-resident macrophages and increase susceptibility to Listeria monocytogenes

    Wang, Y. T., Zaitsev, K., Lu, Q., Li, S., Schaiff, W. T., Kim, K. W., Droit, L., Wilen, C. B., Desai, C., Balce, D. R., Orchard, R. C., Orvedahl, A., Park, S., Kreamalmeyer, D., Handley, S. A., Pfeifer, J. D., Baldridge, M. T., Artyomov, M. N., Stallings, C. L. & Virgin, S., Feb 1 2020, In : Nature microbiology. 5, 2, p. 272-281 10 p.

    Research output: Contribution to journalLetter

  • The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis

    Winkler, E. S., Shrihari, S., Hykes, B. L., Handley, S. A., Andhey, P. S., Huang, Y. J. S., Swain, A., Droit, L., Chebrolu, K. K., Mack, M., Vanlandingham, D. L., Thackray, L., Cella, M., Colonna, M., Artomov, M., Stappenbeck, T. & Diamond, M. S., Aug 20 2020, In : Cell. 182, 4, p. 901-918.e18

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    A Secreted Viral Nonstructural Protein Determines Intestinal Norovirus Pathogenesis

    Lee, S., Liu, H., Wilen, C. B., Sychev, Z. E., Desai, C., Hykes, B. L., Orchard, R. C., McCune, B. T., Kim, K. W., Nice, T. J., Handley, S. A., Baldridge, M. T., Amarasinghe, G. K. & Virgin, H. W., Jun 12 2019, In : Cell Host and Microbe. 25, 6, p. 845-857.e5

    Research output: Contribution to journalArticle

    Open Access
  • 9 Scopus citations