Sarah England

Professor of Obstetrics and Gynecology, Professor of Cell Biology and Physiology, Alan A and Edith L Wolff Professor of Medicine

  • 2429 Citations
1990 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Research interests

My research addresses mechanisms that regulate smooth muscle cell excitability and relaxation. Ion flux in myometrial cells results in changes in membrane excitability. For example, potassium efflux is the primary ionic current responsible for maintaining the resting membrane potential, and contributes significantly to uterine quiescence during pregnancy. In myometrial smooth muscle cells (MSMCs), changes in the expression or activity of K+ channels can translate into inadequate repolarization, leading to aberrant uterine activity and pathophysiological conditions such as preterm labor and post-term labor. The main objective of research in my laboratory is to contribute fundamental knowledge about how the modulation of ion channel expression and function could be used to regulate uterine activity.

Fingerprint Dive into the research topics where Sarah England is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output

  • 2429 Citations
  • 62 Article
  • 8 Review article
  • 1 Comment/debate
  • 1 Editorial

Editorial overview: Pregnancy and the myometrium

Wray, S. & England, S. K., Feb 2020, In : Current Opinion in Physiology. 13, p. iii-vi

Research output: Contribution to journalEditorial

Open Access

Evolving cervical imaging technologies to predict preterm birth

Pizzella, S., El Helou, N., Chubiz, J., Wang, L. V., Tuuli, M. G., England, S. K. & Stout, M. J., 2020, (Accepted/In press) In : Seminars in Immunopathology.

Research output: Contribution to journalReview article

  • Microelectrode array analysis of mouse uterine smooth muscle electrical activity†

    Ma, X., Zhao, P., Wakle-Prabagaran, M., Amazu, C., Malik, M., Wu, W., Wang, H., Wang, Y. & England, S. K., Apr 15 2020, In : Biology of reproduction. 102, 4, p. 935-942 8 p.

    Research output: Contribution to journalArticle

  • Progesterone and estrogen regulate NALCN expression in human myometrial smooth muscle cells

    Amazu, C., Ma, X., Henkes, C., Ferreira, J. J., Santi, C. M. & England, S. K., Apr 2020, In : American Journal of Physiology - Endocrinology and Metabolism. 318, 4, p. E441-E452

    Research output: Contribution to journalArticle

  • Sodium channels and transporters in the myometrium

    Amazu, C., Ferreira, J. J., Santi, C. M. & England, S. K., Feb 2020, In : Current Opinion in Physiology. 13, p. 141-144 4 p.

    Research output: Contribution to journalReview article

    Open Access