Research output per year
Research output per year
- 1 - 50 out of 109 results
Search results
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2023
Lethal neonatal respiratory failure due to biallelic variants in BBS1 and monoallelic variant in TTC21B
Viehl, L., Wegner, D. J., Hmiel, S. P., White, F. V., Jain, S., Cole, F. S. & Wambach, J. A., Feb 2023, In: Pediatric Nephrology. 38, 2, p. 605-609 5 p.Research output: Contribution to journal › Article › peer-review
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2022
An ex vivo culture model of kidney podocyte injury reveals mechanosensitive, synaptopodin-templating, sarcomere-like structures
Jiang, S., Alisafaei, F., Huang, Y. Y., Hong, Y., Peng, X., Qu, C., Puapatanakul, P., Jain, S., Miner, J. H., Genin, G. M. & Suleiman, H. Y., Sep 2022, In: Science Advances. 8, 35, eabn6027.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
A reference tissue atlas for the human kidney
Kidney Precision Medicine Project, Jun 2022, In: Science Advances. 8, 23, eabn4965.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Integrated single-cell sequencing and histopathological analyses reveal diverse injury and repair responses in a participant with acute kidney injury: a clinical-molecular-pathologic correlation
Kidney Precision Medicine Project, Jun 2022, In: Kidney International. 101, 6, p. 1116-1125 10 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Tissue registration and exploration user interfaces in support of a human reference atlas
Börner, K., Bueckle, A., Herr, B. W., Cross, L. E., Quardokus, E. M., Record, E. G., Ju, Y., Silverstein, J. C., Browne, K. M., Jain, S., Wasserfall, C. H., Jorgensen, M. L., Spraggins, J. M., Patterson, N. H. & Weber, G. M., Dec 2022, In: Communications Biology. 5, 1, 1369.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: Guidelines from the kidney precision medicine project
Kidney Precision Medicine Project, 2021, In: Physiological genomics. 53, 1, p. 1-11 11 p.Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
Anatomical structures, cell types and biomarkers of the Human Reference Atlas
Börner, K., Teichmann, S. A., Quardokus, E. M., Gee, J. C., Browne, K., Osumi-Sutherland, D., Herr, B. W., Bueckle, A., Paul, H., Haniffa, M., Jardine, L., Bernard, A., Ding, S. L., Miller, J. A., Lin, S., Halushka, M. K., Boppana, A., Longacre, T. A., Hickey, J., Lin, Y., & 16 others, Nov 2021, In: Nature Cell Biology. 23, 11, p. 1117-1128 12 p.Research output: Contribution to journal › Review article › peer-review
Open Access19 Scopus citations -
A Pilot Study of Urine Proteomics in COVID-19–Associated Acute Kidney Injury
Ye, Y., Swensen, A. C., Wang, Y., Kaushal, M., Salamon, D., Knoten, A., Nicora, C. D., Marks, L., Gaut, J. P., Vijayan, A., Orton, D. J., Mudd, P. A., Parikh, C. R., Qian, W. J., O'Halloran, J. A., Piehowski, P. D. & Jain, S., Dec 2021, In: Kidney International Reports. 6, 12, p. 3064-3069 6 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Automated Computational Detection of Interstitial Fibrosis, Tubular Atrophy, and Glomerulosclerosis
Ginley, B., Jen, K. Y., Han, S. S., Rodrigues, L., Jain, S., Fogo, A. B., Zuckerman, J., Walavalkar, V., Miecznikowski, J. C., Wen, Y., Yen, F., Yun, D., Moon, K. C., Rosenberg, A., Parikh, C. & Sarder, P., Apr 1 2021, In: Journal of the American Society of Nephrology : JASN. 32, 4, p. 837-850 14 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
Cadherin-11, Sparc-related modular calcium binding protein-2, and Pigment epithelium-derived factor are promising non-invasive biomarkers of kidney fibrosis
Kidney Precision Medicine Project (KPMP), Sep 2021, In: Kidney International. 100, 3, p. 672-683 12 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Large-scale, three-dimensional tissue cytometry of the human kidney: a complete and accessible pipeline
for the Kidney Precision Medicine Project, May 2021, In: Laboratory Investigation. 101, 5, p. 661-676 16 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Ontology-based Modeling, Representation, and Analysis of Biomarkers in Healthy and Disease Kidney Tissue
Kidney Precision Medicine Project, 2021, In: CEUR Workshop Proceedings. 3073, p. 70-76 7 p.Research output: Contribution to journal › Conference article › peer-review
1 Scopus citations -
Patient perspectives and involvement in precision medicine research
Kidney Precision Medicine Project, Mar 2021, In: Kidney International. 99, 3, p. 511-514 4 p.Research output: Contribution to journal › Comment/debate
2 Scopus citations -
Plasticity of distal nephron epithelia from human kidney organoids enables the induction of ureteric tip and stalk
Howden, S. E., Wilson, S. B., Groenewegen, E., Starks, L., Forbes, T. A., Tan, K. S., Vanslambrouck, J. M., Holloway, E. M., Chen, Y. H., Jain, S., Spence, J. R. & Little, M. H., Apr 1 2021, In: Cell Stem Cell. 28, 4, p. 671-684.e6Research output: Contribution to journal › Article › peer-review
Open Access52 Scopus citations -
Rationale and design of the Kidney Precision Medicine Project
Kidney Precision Medicine Project, Mar 2021, In: Kidney International. 99, 3, p. 498-510 13 p.Research output: Contribution to journal › Comment/debate
48 Scopus citations -
2020
Fully automated classification of glomerular lesions in lupus nephritis
Ginley, B., Jen, K. Y., Rosenberg, A., Rossi, G. M., Jain, S. & Sarder, P., 2020, Medical Imaging 2020: Digital Pathology. Tomaszewski, J. E. & Ward, A. D. (eds.). SPIE, 113200Y. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11320).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review
5 Scopus citations -
Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project
Kidney Precision Medicine Project, Nov 1 2020, In: Nature Reviews Nephrology. 16, 11, p. 686-696 11 p.Research output: Contribution to journal › Review article › peer-review
30 Scopus citations -
Neutrophil Extracellular Traps (NETs): An unexplored territory in renal pathobiology, a pilot computational study
Santo, B. A., Segal, B. H., Tomaszewski, J. E., Mohammad, I., Worral, A. M., Jain, S., Visser, M. B. & Sarder, P., 2020, Medical Imaging 2020: Digital Pathology. Tomaszewski, J. E. & Ward, A. D. (eds.). SPIE, 1132012. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11320).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review
4 Scopus citations -
Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker
Kidney Precision Medicine Project (KPMP),5 and Nephrotic Syndrome Study Network (NEPTUNE), Mar 26 2020, In: JCI Insight. 5, 6, e133267.Research output: Contribution to journal › Article › peer-review
Open Access69 Scopus citations -
2019
An integrated iterative annotation technique for easing neural network training in medical image analysis
Lutnick, B., Ginley, B., Govind, D., McGarry, S. D., LaViolette, P. S., Yacoub, R., Jain, S., Tomaszewski, J. E., Jen, K. Y. & Sarder, P., Feb 1 2019, In: Nature Machine Intelligence. 1, 2, p. 112-119 8 p.Research output: Contribution to journal › Article › peer-review
75 Scopus citations -
A single-nucleus RNA-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys
Lake, B. B., Chen, S., Hoshi, M., Plongthongkum, N., Salamon, D., Knoten, A., Vijayan, A., Venkatesh, R., Kim, E. H., Gao, D., Gaut, J., Zhang, K. & Jain, S., Dec 1 2019, In: Nature communications. 10, 1, 2832.Research output: Contribution to journal › Article › peer-review
Open Access114 Scopus citations -
A toolbox to characterize human induced pluripotent stem cell-derived kidney cell types and organoids
Vanslambrouck, J. M., Wilson, S. B., Tan, K. S., Soo, J. Y. C., Scurr, M., Spijker, H. S., Starks, L. T., Neilson, A., Cui, X., Jain, S., Little, M. H. & Howden, S. E., 2019, In: Journal of the American Society of Nephrology. 30, 10, p. 1811-1823 13 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
Computational segmentation and classification of diabetic glomerulosclerosis
Ginley, B., Lutnick, B., Jen, K. Y., Fogo, A. B., Jain, S., Rosenberg, A., Walavalkar, V., Wilding, G., Tomaszewski, J. E., Yacoub, R., Rossi, G. M. & Sarder, P., 2019, In: Journal of the American Society of Nephrology. 30, 10, p. 1953-1967 15 p.Research output: Contribution to journal › Article › peer-review
93 Scopus citations -
Developmental pathology of congenital kidney and urinary tract anomalies
Jain, S. & Chen, F., Jun 1 2019, In: Clinical Kidney Journal. 12, 3, p. 382-399 18 p.Research output: Contribution to journal › Review article › peer-review
Open Access45 Scopus citations -
Examining structural patterns and causality in diabetic nephropathy using inter-glomerular distance and Bayesian graphical models
Majumdar, A., Jen, K. Y., Jain, S., Tomaszewski, J. E. & Sarder, P., 2019, Medical Imaging 2019: Digital Pathology. Tomaszewski, J. E. & Ward, A. D. (eds.). SPIE, 1095608. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10956).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review
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FAT4 Fine-Tunes Kidney Development by Regulating RET Signaling
Zhang, H., Bagherie-Lachidan, M., Badouel, C., Enderle, L., Peidis, P., Bremner, R., Kuure, S., Jain, S. & McNeill, H., Mar 25 2019, In: Developmental cell. 48, 6, p. 780-792.e4Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Peroxidasin Is a Novel Target of Autoantibodies in Lupus Nephritis
Manral, P., Colon, S., Bhave, G., Zhao, M. H., Jain, S. & Borza, D. B., Jul 2019, In: Kidney International Reports. 4, 7, p. 1004-1006 3 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
WNT pathway signaling is associated with microvascular injury and predicts kidney transplant failure
Seifert, M. E., Gaut, J. P., Guo, B., Jain, S., Malone, A. F., Geraghty, F., Della Manna, D. L., Yang, E. S., Yi, N., Brennan, D. C. & Mannon, R. B., Oct 1 2019, In: American Journal of Transplantation. 19, 10, p. 2833-2845 13 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2018
Angiotensin II triggers peripheral macrophage-to-sensory neuron redox crosstalk to elicit pain
Shepherd, A. J., Copits, B. A., Mickle, A. D., Karlsson, P., Kadunganattil, S., Haroutounian, S., Tadinada, S. M., De Kloet, A. D., Valtcheva, M. V., McIlvried, L. A., Sheahan, T. D., Jain, S., Ray, P. R., Usachev, Y. M., Dussor, G., Krause, E. G., Price, T. J., Gereau, R. W. & Mohapatra, D. P., Aug 8 2018, In: Journal of Neuroscience. 38, 32, p. 7032-7057 26 p.Research output: Contribution to journal › Article › peer-review
Open Access58 Scopus citations -
Centrosome amplification disrupts renal development and causes cystogenesis'
Dionne, L. K., Shim, K., Hoshi, M., Cheng, T., Wang, J., Marthiens, V., Knoten, A., Basto, R., Jain, S. & Mahjoub, M. R., Jul 2018, In: Journal of Cell Biology. 217, 7, p. 2485-2501 17 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Computational analysis of the structural progression of human glomeruli in diabetic nephropathy
Ginley, B. G., Tomaszewski, J. E., Jen, K. Y., Fogo, A., Jain, S. & Sarder, P., 2018, Medical Imaging 2018: Digital Pathology. Gurcan, M. N. & Tomaszewski, J. E. (eds.). SPIE, 105810A. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10581).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review
5 Scopus citations -
Deep variational auto-encoders for unsupervised glomerular classification
Lutnick, B., Yacoub, R., Jen, K. Y., Tomaszewski, J. E., Jain, S. & Sarder, P., 2018, Medical Imaging 2018: Digital Pathology. Gurcan, M. N. & Tomaszewski, J. E. (eds.). SPIE, 105810C. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10581).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review
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Examining structural changes in diabetic nephropathy using inter-nuclear distances in glomeruli: A comparison of variously automated methods
Simon, O., Yacoub, R., Jain, S., Tomaszewski, J. E. & Sarder, P., 2018, Medical Imaging 2018: Digital Pathology. Gurcan, M. N. & Tomaszewski, J. E. (eds.). SPIE, 105810B. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10581).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review
1 Scopus citations -
Multi-radial LBP Features as a Tool for Rapid Glomerular Detection and Assessment in Whole Slide Histopathology Images
Simon, O., Yacoub, R., Jain, S., Tomaszewski, J. E. & Sarder, P., Dec 1 2018, In: Scientific reports. 8, 1, 2032.Research output: Contribution to journal › Article › peer-review
Open Access56 Scopus citations -
Pathogenic Germline Variants in 10,389 Adult Cancers
The Cancer Genome Atlas Research Network, Apr 5 2018, In: Cell. 173, 2, p. 355-370.e14Research output: Contribution to journal › Article › peer-review
Open Access426 Scopus citations -
Quantification of vascular damage in acute kidney injury with fluorine magnetic resonance imaging and spectroscopy
Moore, J. K., Chen, J., Pan, H., Gaut, J. P., Jain, S. & Wickline, S. A., Jun 2018, In: Magnetic resonance in medicine. 79, 6, p. 3144-3153 10 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Reciprocal spatiotemporally controlled apoptosis regulates Wolffian duct cloaca fusion
Hoshi, M., Reginensi, A., Joens, M. S., Fitzpatrick, J. A. J., McNeill, H. & Jain, S., Mar 2018, In: Journal of the American Society of Nephrology. 29, 3, p. 775-783 9 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Renal Histopathologic Findings Associated with Severity of Clinical Acute Kidney Injury
Kudose, S., Hoshi, M., Jain, S. & Gaut, J. P., 2018, In: American Journal of Surgical Pathology. 42, 5, p. 625-635 11 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
2017
(Re) Building a kidney
Oxburgh, L., Carroll, T. J., Cleaver, O., Gossett, D. R., Hoshizaki, D. K., Hubbell, J. A., Humphreys, B. D., Jain, S., Jensen, J., Kaplan, D. L., Kesselman, C., Ketchum, C. J., Little, M. H., McMahon, A. P., Shankland, S. J., Spence, J. R., Valerius, M. T., Wertheim, J. A., Wessely, O., Zheng, Y., & 1 others, May 2017, In: Journal of the American Society of Nephrology. 28, 5, p. 1370-1378 9 p.Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations -
B cell-derived IL-4 acts on podocytes to induce proteinuria and foot process effacement
Kim, A. H. J., Chung, J. J., Akilesh, S., Koziell, A., Jain, S., Hodgin, J. B., Miller, M. J., Stappenbeck, T. S., Miner, J. H. & Shaw, A. S., Nov 2 2017, In: JCI Insight. 2, 21, e81836.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
Injury-induced actin cytoskeleton reorganization in podocytes revealed by super-resolution microscopy
Suleiman, H. Y., Roth, R., Jain, S., Heuser, J. E., Shaw, A. S. & Miner, J. H., Aug 17 2017, In: JCI Insight. 2, 16, e94137.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
Routine use of clinical exome-based next-generation sequencing for evaluation of patients with thrombotic microangiopathies
Gaut, J. P., Jain, S., Pfeifer, J. D., Vigh-Conrad, K. A., Corliss, M., Sharma, M. K., Heusel, J. W. & Cottrell, C. E., Dec 1 2017, In: Modern Pathology. 30, 12, p. 1739-1747 9 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
2016
7-dehydrocholesterol efficiently supports Ret signaling in a mouse model of Smith-Opitz-Lemli syndrome
Gou-Fàbregas, M., MacIà, A., Anerillas, C., Vaquero, M., Jové, M., Jain, S., Ribera, J. & Encinas, M., Jun 23 2016, In: Scientific reports. 6, 28534.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Adventitial MSC-like Cells Are Progenitors of Vascular Smooth Muscle Cells and Drive Vascular Calcification in Chronic Kidney Disease
Kramann, R., Goettsch, C., Wongboonsin, J., Iwata, H., Schneider, R. K., Kuppe, C., Kaesler, N., Chang-Panesso, M., Machado, F. G., Gratwohl, S., Madhurima, K., Hutcheson, J. D., Jain, S., Aikawa, E. & Humphreys, B. D., Nov 3 2016, In: Cell Stem Cell. 19, 5, p. 628-642 15 p.Research output: Contribution to journal › Article › peer-review
Open Access199 Scopus citations -
A multiplexed analysis approach identifies new association of inflammatory proteins in patients with overactive bladder
Ma, E., Vetter, J., Bliss, L., Lai, H. H., Mysorekar, I. U. & Jain, S., Jul 1 2016, In: American Journal of Physiology - Renal Physiology. 311, 1, p. F28-F34Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis
Yu, H., Artomov, M., Brähler, S., Stander, M. C., Shamsan, G., Sampson, M. G., White, J. M., Kretzler, M., Miner, J. H., Jain, S., Winkler, C. A., Mitra, R. D., Kopp, J. B., Daly, M. J. & Shaw, A. S., Mar 1 2016, In: Journal of Clinical Investigation. 126, 3, p. 1067-1078 12 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
Erratum: A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis (American Society for Clinical Investigation (2016) 126:3 (1067-1078) DOI: 10.1172/JCI82592)
Yu, H., Artomov, M., Brähler, S., Stander, M. C., Shamsan, G., Sampson, M. G., White, J. M., Kretzler, M., Miner, J. H., Jain, S., Winkler, C. A., Mitra, R. D., Kopp, J. B., Daly, M. J. & Shaw, A. S., Apr 1 2016, In: Journal of Clinical Investigation. 126, 4, p. 1603 1 p.Research output: Contribution to journal › Comment/debate
Open Access6 Scopus citations -
Erratum: A role for genetic susceptibility in sporadic focal segmental glomerulosclerosis (Journal of Clinical Investigation(2016)126: 3(1067-1078)Doi: 10.1172/JCI82592)
Yu, H., Artomov, M., Brähler, S., Christine Stander, M., Shamsan, G., Sampson, M. G., Michael White, J., Kretzler, M., Miner, J. H., Jain, S., Winkler, C. A., Mitra, R. D., Kopp, J. B., Daly, M. J. & Shaw, A. S., Apr 1 2016, In: Journal of Clinical Investigation. 126, 4, p. 1603-1604 2 p.Research output: Contribution to journal › Comment/debate
Open Access3 Scopus citations -
Genome-wide significance testing of variation from single case exomes
Wilfert, A. B., Chao, K. R., Kaushal, M., Jain, S., Zöllner, S., Adams, D. R. & Conrad, D. F., Dec 1 2016, In: Nature Genetics. 48, 12, p. 1455-1461 7 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
Glial cell line-derived neurotrophic factor protects against high-fat diet-induced hepatic steatosis by suppressing hepatic PPAR-γ expression
Mwangi, S. M., Peng, S., Nezami, B. G., Thorn, N., Farris, A. B., Jain, S., Laroui, H., Merlin, D., Anania, F. & Srinivasan, S., 2016, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 310, 2, p. G103-G116Research output: Contribution to journal › Article › peer-review
10 Scopus citations