Samuel Klein

2024

A multisociety Delphi consensus statement on new fatty liver disease nomenclature

NAFLD Nomenclature consensus group, Jan 1 2024, In: Annals of Hepatology. 29, 1, 101133.

Research output: Contribution to journal › Review article › peer-review

Open Access

Cardiometabolic characteristics of people with metabolically healthy and unhealthy obesity

Petersen, M. C., Smith, G. I., Palacios, H. H., Farabi, S. S., Yoshino, M., Yoshino, J., Cho, K., Davila-Roman, V. G., Shankaran, M., Barve, R. A., Yu, J., Stern, J. H., Patterson, B. W., Hellerstein, M. K., Shulman, G. I., Patti, G. J. & Klein, S., Apr 2 2024, In: Cell metabolism. 36, 4, p. 745-761.e5

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Cardio-renal-metabolic disease in primary care setting

Ibrahim, M., Ba-Essa, E. M., Baker, J., Cahn, A., Ceriello, A., Cosentino, F., Davies, M. J., Eckel, R. H., Van Gaal, L., Gaede, P., Handelsman, Y., Klein, S., Leslie, R. D., Pozzilli, P., Del Prato, S., Prattichizzo, F., Schnell, O., Seferovic, P. M., Standl, E. & Thomas, A. & 3 others, Tuomilehto, J., Valensi, P. & Umpierrez, G. E., Mar 2024, In: Diabetes/Metabolism Research and Reviews. 40, 3, e3755.

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Control of lipolysis by a population of oxytocinergic sympathetic neurons

Li, E., Wang, L., Wang, D., Chi, J., Lin, Z., Smith, G. I., Klein, S., Cohen, P. & Rosen, E. D., Jan 4 2024, In: Nature. 625, 7993, p. 175-180 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Critical Evaluation of Indices Used to Assess b-Cell Function

Cao, C., Koh, H. C. E., Reeds, D. N., Patterson, B. W., Klein, S. & Mittendorfer, B., Mar 2024, In: Diabetes. 73, 3, p. 391-400 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Impaired plasma glucose clearance is a key determinant of fasting hyperglycemia in people with obesity

Mittendorfer, B., van Vliet, S., Smith, G. I., Petersen, M. C., Patterson, B. W. & Klein, S., Mar 2024, In: Obesity. 32, 3, p. 540-546 7 p.

Research output: Contribution to journal › Article › peer-review

Is Weight Loss-Induced Muscle Mass Loss Clinically Relevant?

Conte, C., Hall, K. D. & Klein, S., Jul 2 2024, In: JAMA. 332, 1, p. 9-10 2 p.

Research output: Contribution to journal › Short survey › peer-review

8 Scopus citations

Very-low-density lipoprotein triglyceride and free fatty acid plasma kinetics in women with high or low brown adipose tissue volume and overweight/obesity

Chondronikola, M., Yoshino, J., Ramaswamy, R., Giardina, J. D., Laforest, R., Wahl, R. L., Patterson, B. W., Mittendorfer, B. & Klein, S., Jan 16 2024, In: Cell Reports Medicine. 5, 1, 101370.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

2023

A multisociety Delphi consensus statement on new fatty liver disease nomenclature

Rinella, M. E., Lazarus, J. V., Ratziu, V., Francque, S. M., Sanyal, A. J., Kanwal, F., Romero, D., Abdelmalek, M. F., Anstee, Q. M., Arab, J. P., Arrese, M., Bataller, R., Beuers, U., Boursier, J., Bugianesi, E., Byrne, C. D., Castro Narro, G. E., Chowdhury, A., Cortez-Pinto, H. & Cryer, D. R. & 33 others, Cusi, K., El-Kassas, M., Klein, S., Eskridge, W., Fan, J., Gawrieh, S., Guy, C. D., Harrison, S. A., Kim, S. U., Koot, B. G., Korenjak, M., Kowdley, K. V., Lacaille, F., Loomba, R., Mitchell-Thain, R., Morgan, T. R., Powell, E. E., Roden, M., Romero-Gómez, M., Silva, M., Singh, S. P., Sookoian, S. C., Spearman, C. W., Tiniakos, D., Valenti, L., Vos, M. B., Wong, V. W. S., Xanthakos, S., Yilmaz, Y., Younossi, Z., Hobbs, A., Villota-Rivas, M. & Newsome, P. N., Dec 2023, In: Hepatology. 78, 6, p. 1966-1986 21 p.

Research output: Contribution to journal › Article › peer-review

Open Access

682 Scopus citations

A multisociety Delphi consensus statement on new fatty liver disease nomenclature

NAFLD Nomenclature consensus group & Klein, S., Dec 2023, In: Journal of Hepatology. 79, 6, p. 1542-1556 15 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

803 Scopus citations

Dietary weight loss-induced improvements in metabolic function are enhanced by exercise in people with obesity and prediabetes

Beals, J. W., Kayser, B. D., Smith, G. I., Schweitzer, G. G., Kirbach, K., Kearney, M. L., Yoshino, J., Rahman, G., Knight, R., Patterson, B. W. & Klein, S., Jul 2023, In: Nature Metabolism. 5, 7, p. 1221-1235 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Dorsal striatal response to taste is modified by obesity and insulin resistance

Dunn, J. P., Lamichhane, B., Smith, G. I., Garner, A., Wallendorf, M., Hershey, T. & Klein, S., Aug 2023, In: Obesity. 31, 8, p. 2065-2075 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Early intervention and intensive management of patients with diabetes, cardiorenal, and metabolic diseases

Handelsman, Y., Butler, J., Bakris, G. L., DeFronzo, R. A., Fonarow, G. C., Green, J. B., Grunberger, G., Januzzi, J. L., Klein, S., Kushner, P. R., McGuire, D. K., Michos, E. D., Morales, J., Pratley, R. E., Weir, M. R., Wright, E. & Fonseca, V. A., Feb 2023, In: Journal of Diabetes and Its Complications. 37, 2, 108389.

Research output: Contribution to journal › Review article › peer-review

Open Access

24 Scopus citations

Heterogeneity in the effect of marked weight loss on metabolic function in women with obesity

Mittendorfer, B., Kayser, B. D., Yoshino, M., Yoshino, J., Watrous, J. D., Jain, M., Eagon, J. C., Patterson, B. W. & Klein, S., 2023, In: JCI Insight. 8, 12, e169541.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Insulin sensitivity and β-cell function during early and late pregnancy in women with and without gestational diabetes mellitus

Mittendorfer, B., Patterson, B. W., Haire-Joshu, D., Cahill, A. G., Cade, W. T., Stein, R. I. & Klein, S., Dec 2023, In: Diabetes care. 46, 12, p. 2147-2154 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Publisher Correction: Glucagon receptor antagonist volagidemab in type 1 diabetes: a 12-week, randomized, double-blind, phase 2 trial (Nature Medicine, (2022), 28, 10, (2092-2099), 10.1038/s41591-022-02011-x)

Pettus, J., Boeder, S. C., Christiansen, M. P., Denham, D. S., Bailey, T. S., Akturk, H. K., Klaff, L. J., Rosenstock, J., Cheng, M. H. M., Bode, B. W., Bautista, E. D., Xu, R., Yan, H., Thai, D., Garg, S. K. & Klein, S., Nov 2023, In: Nature medicine. 29, 11, p. 2959 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

Short-term Intensive Lifestyle Therapy in a Worksite Setting Improves Cardiometabolic Health in People With Obesity

Schweitzer, G. G., Beckner, D. C., Smith, G. I. & Klein, S., Jun 1 2023, In: Journal of the Endocrine Society. 7, 6, bvad048.

Research output: Contribution to journal › Article › peer-review

Open Access

Steatosis drives monocyte-derived macrophage accumulation in human metabolic dysfunction-associated fatty liver disease

Chan, M. M., Daemen, S., Beals, J. W., Terekhova, M., Yang, B. Q., Fu, C. F., He, L., Park, A. C., Smith, G. I., Razani, B., Byrnes, K., Beatty, W. L., Eckhouse, S. R., Eagon, J. C., Ferguson, D., Finck, B. N., Klein, S., Artyomov, M. N. & Schilling, J. D., Nov 2023, In: JHEP Reports. 5, 11, 100877.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Weight versus weight-independent effects of Roux-en-Y gastric bypass on type 2 diabetes

Klein, S. & Seeley, R. J., Jun 2023, In: Nature Metabolism. 5, 6, p. 912-914 3 p.

Research output: Contribution to journal › Comment/debate

3 Scopus citations

β Cell function after Roux-en-Y gastric bypass surgery or reduced energy intake alone in people with obesity

Mittendorfer, B., Patterson, B. W., Magkos, F., Yoshino, M., Bradley, D. P., Eagon, J. C. & Klein, S., 2023, In: JCI Insight. 8, 12, e170307.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

ADRA1A–Gα_q signalling potentiates adipocyte thermogenesis through CKB and TNAP

Rahbani, J. F., Scholtes, C., Lagarde, D. M., Hussain, M. F., Roesler, A., Dykstra, C. B., Bunk, J., Samborska, B., O’Brien, S. L., Tripp, E., Pacis, A., Angueira, A. R., Johansen, O. S., Cinkornpumin, J., Hossain, I., Lynes, M. D., Zhang, Y., White, A. P., Pastor, W. A. & Chondronikola, M. & 12 others, Sidossis, L., Klein, S., Kralli, A., Cypess, A. M., Pedersen, S. B., Jessen, N., Tseng, Y. H., Gerhart-Hines, Z., Seale, P., Calebiro, D., Giguère, V. & Kazak, L., Nov 2022, In: Nature Metabolism. 4, 11, p. 1459-1473 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Architecture of the outbred brown fat proteome defines regulators of metabolic physiology

Xiao, H., Bozi, L. H. M., Sun, Y., Riley, C. L., Philip, V. M., Chen, M., Li, J., Zhang, T., Mills, E. L., Emont, M. P., Sun, W., Reddy, A., Garrity, R., Long, J., Becher, T., Vitas, L. P., Laznik-Bogoslavski, D., Ordonez, M., Liu, X. & Chen, X. & 26 others, Wang, Y., Liu, W., Tran, N., Liu, Y., Zhang, Y., Cypess, A. M., White, A. P., He, Y., Deng, R., Schöder, H., Paulo, J. A., Jedrychowski, M. P., Banks, A. S., Tseng, Y. H., Cohen, P., Tsai, L. T., Rosen, E. D., Klein, S., Chondronikola, M., McAllister, F. E., Van Bruggen, N., Huttlin, E. L., Spiegelman, B. M., Churchill, G. A., Gygi, S. P. & Chouchani, E. T., Nov 23 2022, In: Cell. 185, 24, p. 4654-4673.e28

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Complex physiology and clinical implications of time-restricted eating

Petersen, M. C., Gallop, M. R., Ramos, S. F., Zarrinpar, A., Broussard, J. L., Chondronikola, M., Chaix, A. & Klein, S., Oct 2022, In: Physiological reviews. 102, 4, p. 1991-2034 44 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

20 Scopus citations

Do lifestyle factors and quality of life differ in people with metabolically healthy and unhealthy obesity?

Farabi, S. S., Smith, G. I., Schweitzer, G. G., Stein, R. I. & Klein, S., Oct 2022, In: International Journal of Obesity. 46, 10, p. 1778-1785 8 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Effect of excessive gestational weight gain on insulin sensitivity and insulin kinetics in women with overweight/obesity

Cade, W. T., Mittendorfer, B., Patterson, B. W., Haire-Joshu, D., Cahill, A. G., Stein, R. I., Schechtman, K. B., Tinius, R. A., Brown, K. & Klein, S., Oct 2022, In: Obesity. 30, 10, p. 2014-2022 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Effects of Mindfulness Training and Exercise on Cognitive Function in Older Adults: A Randomized Clinical Trial

Lenze, E. J., Voegtle, M., Miller, J. P., Ances, B. M., Balota, D. A., Barch, D., Depp, C. A., Diniz, B. S., Eyler, L. T., Foster, E. R., Gettinger, T. R., Head, D., Hershey, T., Klein, S., Nichols, J. F., Nicol, G. E., Nishino, T., Patterson, B. W., Rodebaugh, T. L. & Schweiger, J. & 10 others, Shimony, J. S., Sinacore, D. R., Snyder, A. Z., Tate, S., Twamley, E. W., Wing, D., Wu, G. F., Yang, L., Yingling, M. D. & Wetherell, J. L., Dec 13 2022, In: JAMA. 328, 22, p. 2218-2229 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

43 Scopus citations

Erratum: Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids (Cell Reports (2022) 39(4), (S2211124722004946), (10.1016/j.celrep.2022.110733))

Martino, M. R., Gutiérrez-Aguilar, M., Yiew, N. K. H., Lutkewitte, A. J., Singer, J. M., McCommis, K., Ferguson, D., Liss, K. H. H., Yoshino, J., Renkemeyer, M. K., Smith, G., Cho, K., Fletcher, J. A., Klein, S., Patti, G. J., Burgess, S. C. & Finck, B. N., Nov 15 2022, In: Cell Reports. 41, 7, 111633.

Research output: Contribution to journal › Comment/debate

Open Access

3 Scopus citations

Erratum: Dynamic Shifts in the Composition of Resident and Recruited Macrophages Influence Tissue Remodeling in NASH (Cell Reports (2021) 34(2), (S2211124720316156), (10.1016/j.celrep.2020.108626))

Daemen, S., Gainullina, A., Kalugotla, G., He, L., Chan, M. M., Beals, J. W., Liss, K. H., Klein, S., Feldstein, A. E., Finck, B. N., Artyomov, M. N. & Schilling, J., Nov 15 2022, In: Cell Reports. 41, 7, 111660.

Research output: Contribution to journal › Comment/debate

Open Access

3 Scopus citations

Find the latest version: https://jci.me/154068/pdf β Cell function and plasma insulin clearance in people with obesity and different glycemic status

Mittendorfer, B., Patterson, B. W., Smith, G. I., Yoshino, M. & Klein, S., Feb 1 2022, In: Journal of Clinical Investigation. 132, 3, e154068.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

Focus on diet and exercise

Speakman, J., Johnstone, A., Moholdt, T., Panda, S., Klein, S., Parker, B. L. & Goodyear, L., Oct 4 2022, In: Cell metabolism. 34, 10, p. 1416-1419 4 p.

Research output: Contribution to journal › Comment/debate

Open Access

Glucagon-like peptide-1, glucose-dependent insulinotropic polypeptide, and glucagon receptor poly-agonists: a new era in obesity pharmacotherapy

Malik, I. H. O., Petersen, M. C. & Klein, S., Sep 2022, In: Obesity. 30, 9, p. 1718-1721 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Glucagon receptor antagonist volagidemab in type 1 diabetes: a 12-week, randomized, double-blind, phase 2 trial

Pettus, J., Boeder, S. C., Christiansen, M. P., Denham, D. S., Bailey, T. S., Akturk, H. K., Klaff, L. J., Rosenstock, J., Cheng, M. H. M., Bode, B. W., Bautista, E. D., Xu, R., Yan, H., Thai, D., Garg, S. K. & Klein, S., Oct 2022, In: Nature medicine. 28, 10, p. 2092-2099 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Insufficient sleep and obesity: cause or consequence

Broussard, J. L. & Klein, S., Oct 2022, In: Obesity. 30, 10, p. 1914-1916 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Licogliflozin for nonalcoholic steatohepatitis: a randomized, double-blind, placebo-controlled, phase 2a study

Harrison, S. A., Manghi, F. P., Smith, W. B., Alpenidze, D., Aizenberg, D., Klarenbeek, N., Chen, C. Y., Zuckerman, E., Ravussin, E., Charatcharoenwitthaya, P., Cheng, P. N., Katchman, H., Klein, S., Ben-Ari, Z., Mendonza, A. E., Zhang, Y., Martic, M., Ma, S., Kao, S. & Tanner, S. & 5 others, Pachori, A., Badman, M. K., He, Y. L., Ukomadu, C. & Sicard, E., Jul 2022, In: Nature medicine. 28, 7, p. 1432-1438 7 p.

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Metabolic subtypes of patients with NAFLD exhibit distinctive cardiovascular risk profiles

Martínez-Arranz, I., Bruzzone, C., Noureddin, M., Gil-Redondo, R., Mincholé, I., Bizkarguenaga, M., Arretxe, E., Iruarrizaga-Lejarreta, M., Fernández-Ramos, D., Lopitz-Otsoa, F., Mayo, R., Embade, N., Newberry, E., Mittendorf, B., Izquierdo-Sánchez, L., Smid, V., Arnold, J., Iruzubieta, P., Pérez Castaño, Y. & Krawczyk, M. & 21 others, Marigorta, U. M., Morrison, M. C., Kleemann, R., Martín-Duce, A., Hayardeny, L., Vitek, L., Bruha, R., Aller de la Fuente, R., Crespo, J., Romero-Gomez, M., Banales, J. M., Arrese, M., Cusi, K., Bugianesi, E., Klein, S., Lu, S. C., Anstee, Q. M., Millet, O., Davidson, N. O., Alonso, C. & Mato, J. M., Oct 2022, In: Hepatology. 76, 4, p. 1121-1134 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Physiological interindividual variability in endogenous estradiol concentration does not influence adipose tissue and hepatic lipid kinetics in women

Magkos, F., Fabbrini, E., Patterson, B. W., Mittendorfer, B. & Klein, S., Sep 2022, In: European Journal of Endocrinology. 187, 3, p. 391-398 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Reply to G Taubes, MI Friedman, and V Torres-Carot et al.

Hall, K. D., Farooqi, I. S., Friedman, J. M., Klein, S., Loos, R. J. F., Mangelsdorf, D. J., O’Rahilly, S., Ravussin, E., Redman, L. M., Ryan, D. H., Speakman, J. R. & Tobias, D. K., Aug 1 2022, In: American Journal of Clinical Nutrition. 116, 2, p. 614-616 3 p.

Research output: Contribution to journal › Letter › peer-review

Open Access

1 Scopus citations

Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids

Martino, M. R., Gutiérrez-Aguilar, M., Yiew, N. K. H., Lutkewitte, A. J., Singer, J. M., McCommis, K., Ferguson, D., Liss, K. H. H., Yoshino, J., Renkemeyer, M. K., Smith, G. I., Cho, K., Fletcher, J. A., Klein, S., Patti, G. J., Burgess, S. C. & Finck, B. N., Apr 26 2022, In: Cell Reports. 39, 4, 110733.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes

Gunasekar, S. K., Xie, L., Kumar, A., Hong, J., Chheda, P. R., Kang, C., Kern, D. M., My-Ta, C., Maurer, J., Heebink, J., Gerber, E. E., Grzesik, W. J., Elliot-Hudson, M., Zhang, Y., Key, P., Kulkarni, C. A., Beals, J. W., Smith, G. I., Samuel, I. & Smith, J. K. & 10 others, Nau, P., Imai, Y., Sheldon, R. D., Taylor, E. B., Lerner, D. J., Norris, A. W., Klein, S., Brohawn, S. G., Kerns, R. & Sah, R., Dec 2022, In: Nature communications. 13, 1, 784.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

The energy balance model of obesity: beyond calories in, calories out

Hall, K. D., Farooqi, I. S., Friedman, J. M., Klein, S., Loos, R. J. F., Mangelsdorf, D. J., O'Rahilly, S., Ravussin, E., Redman, L. M., Ryan, D. H., Speakman, J. R. & Tobias, D. K., May 1 2022, In: American Journal of Clinical Nutrition. 115, 5, p. 1243-1254 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

148 Scopus citations

The rheumatoid arthritis drug auranofin lowers leptin levels and exerts antidiabetic effects in obese mice

Cox, A. R., Masschelin, P. M., Saha, P. K., Felix, J. B., Sharp, R., Lian, Z., Xia, Y., Chernis, N., Bader, D. A., Kim, K. H., Li, X., Yoshino, J., Li, G., Sun, Z., Wu, H., Coarfa, C., Moore, D. D., Klein, S., Sun, K. & Hartig, S. M., Dec 6 2022, In: Cell metabolism. 34, 12, p. 1932-1946.e7

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Why does obesity cause diabetes?

Klein, S., Gastaldelli, A., Yki-Järvinen, H. & Scherer, P. E., Jan 4 2022, In: Cell metabolism. 34, 1, p. 11-20 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

276 Scopus citations

Worksite-based intensive lifestyle therapy has profound cardiometabolic benefits in people with obesity and type 2 diabetes

Yoshino, M., Yoshino, J., Smith, G. I., Stein, R. I., Bittel, A. J., Bittel, D. C., Reeds, D. N., Sinacore, D. R., Cade, T., Patterson, B. W., Cho, K., Patti, G. J., Mittendorfer, B. & Klein, S., Oct 4 2022, In: Cell metabolism. 34, 10, p. 1431-1441.e5

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

2021

A critical role of hepatic GABA in the metabolic dysfunction and hyperphagia of obesity

Geisler, C. E., Ghimire, S., Bruggink, S. M., Miller, K. E., Weninger, S. N., Kronenfeld, J. M., Yoshino, J., Klein, S., Duca, F. A. & Renquist, B. J., Jun 29 2021, In: Cell Reports. 35, 13, 109301.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis

Zhu, Y., Li, N., Huang, M., Bartels, M., Dogné, S., Zhao, S., Chen, X., Crewe, C., Straub, L., Vishvanath, L., Zhang, Z., Shao, M., Yang, Y., Gliniak, C. M., Gordillo, R., Smith, G. I., Holland, W. L., Gupta, R. K., Dong, B. & Caron, N. & 4 others, Xu, Y., Akgul, Y., Klein, S. & Scherer, P. E., Dec 1 2021, In: Nature communications. 12, 1, 4829.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Associations Among Adipose Tissue Immunology, Inflammation, Exosomes and Insulin Sensitivity in People With Obesity and Nonalcoholic Fatty Liver Disease

Fuchs, A., Samovski, D., Smith, G. I., Cifarelli, V., Farabi, S. S., Yoshino, J., Pietka, T., Chang, S. W., Ghosh, S., Myckatyn, T. M. & Klein, S., Sep 2021, In: Gastroenterology. 161, 3, p. 968-981.e12

Research output: Contribution to journal › Article › peer-review

Open Access

94 Scopus citations

Attenuated early pregnancy weight gain by prenatal lifestyle interventions does not prevent gestational diabetes in the LIFE-Moms consortium

the LIFE-Moms Research Group, Jan 2021, In: Diabetes Research and Clinical Practice. 171, 108549.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Describing the Weight-Reduced State: Physiology, Behavior, and Interventions

Aronne, L. J., Hall, K. D., M. Jakicic, J., Leibel, R. L., Lowe, M. R., Rosenbaum, M. & Klein, S., Apr 2021, In: Obesity. 29, S1, p. S9-S24

Research output: Contribution to journal › Article › peer-review

Open Access

54 Scopus citations

Dynamic Shifts in the Composition of Resident and Recruited Macrophages Influence Tissue Remodeling in NASH

Daemen, S., Gainullina, A., Kalugotla, G., He, L., Chan, M. M., Beals, J. W., Liss, K. H., Klein, S., Feldstein, A. E., Finck, B. N., Artyomov, M. N. & Schilling, J. D., Jan 12 2021, In: Cell Reports. 34, 2, 108626.

Research output: Contribution to journal › Article › peer-review

Open Access

177 Scopus citations

Evaluating microbiome-directed fibre snacks in gnotobiotic mice and humans

Delannoy-Bruno, O., Desai, C., Raman, A. S., Chen, R. Y., Hibberd, M. C., Cheng, J., Han, N., Castillo, J. J., Couture, G., Lebrilla, C. B., Barve, R. A., Lombard, V., Henrissat, B., Leyn, S. A., Rodionov, D. A., Osterman, A. L., Hayashi, D. K., Meynier, A., Vinoy, S. & Kirbach, K. & 5 others, Wilmot, T., Heath, A. C., Klein, S., Barratt, M. J. & Gordon, J. I., Jul 1 2021, In: Nature. 595, 7865, p. 91-95 5 p.

Research output: Contribution to journal › Article › peer-review

73 Scopus citations

Samuel Klein

Research output

Search results