Research output per year
Research output per year
Personal profile
Research interests
Dr. Klein’s research involves the use of stable isotope tracers to study substrate metabolism in human subjects. His major research interest involves learning how obesity contributes to metabolic disease. His work has increased the understanding of normal adipose tissue physiology, the alterations in fat metabolism associated with obesity and fatty liver disease, and how weight loss improves the metabolic problems caused by obesity. He is also involved in conducting clinical trials to evaluate the safety and efficacy of obesity therapies.
Clinical interests
Obesity, nutrition, weight management, gastroenterology, metabolism
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Collaborations and top research areas from the last five years
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Adipose Tissue Biology and Effect of Weight Loss in Women With Lipedema
Cifarelli, V., Smith, G. I., Gonzalez-Nieves, S., Samovski, D., Palacios, H. H., Yoshino, J., Stein, R. I., Fuchs, A., Wright, T. F. & Klein, S., Mar 2025, In: Diabetes. 74, 3, p. 308-319 12 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Effects of Obesity and Hyperglycemia on Postprandial Insulin-Mediated and Non–Insulin-Mediated Glucose Disposal
Mittendorfer, B., Patterson, B. W., Smith, G. I., Yoshino, M. & Klein, S., Jan 2025, In: Diabetes care. 48, 1, p. 84-92 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Adipocyte lipin 1 expression associates with human metabolic health and regulates systemic metabolism in mice
LaPoint, A., Singer, J. M., Ferguson, D., Shew, T. M., Renkemeyer, M. K., Palacios, H. H., Field, R. L., Yerrathota, S., Kumari, R., Shankaran, M., Smith, G. I., Yoshino, J., He, M., Patti, G. J., Hellerstein, M. K., Klein, S., Brestoff, J. R., Morris, E. M., Finck, B. N. & Lutkewitte, A. J., Dec 2 2024, In: Journal of Clinical Investigation. 134, 23, e169722.Research output: Contribution to journal › Article › peer-review
Open Access -
A multisociety Delphi consensus statement on new fatty liver disease nomenclature
NAFLD Nomenclature consensus group, Rinella, M. E., Lazarus, J. V., Ratziu, V., Francque, S. M., Sanyal, A. J., Kanwal, F., Romero, D., Abdelmalek, M. F., Anstee, Q. M., Arab, J. P., Arrese, M., Bataller, R., Beuers, U., Boursier, J., Bugianesi, E., Byrne, C. D., Narro, G. E. C., Chowdhury, A. & Cortez-Pinto, H. & 34 others, , Jan 1 2024, In: Annals of Hepatology. 29, 1, 101133.Research output: Contribution to journal › Review article › peer-review
Open Access354 Scopus citations -
Cardiometabolic characteristics of people with metabolically healthy and unhealthy obesity
Petersen, M. C., Smith, G. I., Palacios, H. H., Farabi, S. S., Yoshino, M., Yoshino, J., Cho, K., Davila-Roman, V. G., Shankaran, M., Barve, R. A., Yu, J., Stern, J. H., Patterson, B. W., Hellerstein, M. K., Shulman, G. I., Patti, G. J. & Klein, S., Apr 2 2024, In: Cell metabolism. 36, 4, p. 745-761.e5Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations