Research output per year
Research output per year
Personal profile
Research interests
Dr. Klein’s research involves the use of stable isotope tracers to study substrate metabolism in human subjects. His major research interest involves learning how obesity contributes to metabolic disease. His work has increased the understanding of normal adipose tissue physiology, the alterations in fat metabolism associated with obesity and fatty liver disease, and how weight loss improves the metabolic problems caused by obesity. He is also involved in conducting clinical trials to evaluate the safety and efficacy of obesity therapies.
Clinical interests
Obesity, nutrition, weight management, gastroenterology, metabolism
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ADRA1A–Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP
Rahbani, J. F., Scholtes, C., Lagarde, D. M., Hussain, M. F., Roesler, A., Dykstra, C. B., Bunk, J., Samborska, B., O’Brien, S. L., Tripp, E., Pacis, A., Angueira, A. R., Johansen, O. S., Cinkornpumin, J., Hossain, I., Lynes, M. D., Zhang, Y., White, A. P., Pastor, W. A., Chondronikola, M., & 12 others, Nov 2022, In: Nature Metabolism. 4, 11, p. 1459-1473 15 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Architecture of the outbred brown fat proteome defines regulators of metabolic physiology
Xiao, H., Bozi, L. H. M., Sun, Y., Riley, C. L., Philip, V. M., Chen, M., Li, J., Zhang, T., Mills, E. L., Emont, M. P., Sun, W., Reddy, A., Garrity, R., Long, J., Becher, T., Vitas, L. P., Laznik-Bogoslavski, D., Ordonez, M., Liu, X., Chen, X., & 26 others, Nov 23 2022, In: Cell. 185, 24, p. 4654-4673.e28Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Complex physiology and clinical implications of time-restricted eating
Petersen, M. C., Gallop, M. R., Ramos, S. F., Zarrinpar, A., Broussard, J. L., Chondronikola, M., Chaix, A. & Klein, S., Oct 2022, In: Physiological reviews. 102, 4, p. 1991-2034 44 p.Research output: Contribution to journal › Review article › peer-review
4 Scopus citations -
Do lifestyle factors and quality of life differ in people with metabolically healthy and unhealthy obesity?
Farabi, S. S., Smith, G. I., Schweitzer, G. G., Stein, R. I. & Klein, S., Oct 2022, In: International Journal of Obesity. 46, 10, p. 1778-1785 8 p.Research output: Contribution to journal › Article › peer-review
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Effect of excessive gestational weight gain on insulin sensitivity and insulin kinetics in women with overweight/obesity
Cade, W. T., Mittendorfer, B., Patterson, B. W., Haire-Joshu, D., Cahill, A. G., Stein, R. I., Schechtman, K. B., Tinius, R. A., Brown, K. & Klein, S., Oct 2022, In: Obesity. 30, 10, p. 2014-2022 9 p.Research output: Contribution to journal › Article › peer-review
Open Access