S. Peter Goedegebuure

2024

Overexpression of human DNA polymerase theta is a biomarker of aggressive and DNA repair-deficient papillary thyroid cancers

Frye, C. C., Tennant, L., Yeager, A., Azimzadeh, P., Bhardwaj, P., Xu, Y., Liu, J., Othoum, G., Maher, C. A., Chernock, R., Goedegebuure, S. P., Gillanders, W., Olson, J. A. & Brown, T. C., Nov 2024, In: Surgery (United States). 176, 5, p. 1380-1387 8 p.

Research output: Contribution to journal › Article › peer-review

sc2MeNetDrug: A computational tool to uncover inter-cell signaling targets and identify relevant drugs based on single cell RNA-seq data

Feng, J., Goedegebuure, S. P., Zeng, A., Bi, Y., Wang, T., Payne, P., Ding, L., DeNardo, D., Hawkins, W., Fields, R. C. & Li, F., Jan 2024, In: PLoS computational biology. 20, 1, e1011785.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

The novel drug candidate S2/IAPinh improves survival in models of pancreatic and ovarian cancer

Hagi, T., Vangveravong, S., Takchi, R., Gong, Q., Goedegebuure, S. P., Tiriac, H., Van Tine, B. A., Powell, M. A., Hawkins, W. G. & Spitzer, D., Dec 2024, In: Scientific reports. 14, 1, 6373.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment

Chiorazzi, M., Martinek, J., Krasnick, B., Zheng, Y., Robbins, K. J., Qu, R., Kaufmann, G., Skidmore, Z., Juric, M., Henze, L. A., Brösecke, F., Adonyi, A., Zhao, J., Shan, L., Sefik, E., Mudd, J., Bi, Y., Goedegebuure, S. P., Griffith, M. & Griffith, O. & 14 others, Oyedeji, A., Fertuzinhos, S., Garcia-Milian, R., Boffa, D., Detterbeck, F., Dhanasopon, A., Blasberg, J., Judson, B., Gettinger, S., Politi, K., Kluger, Y., Palucka, K., Fields, R. C. & Flavell, R. A., Jul 24 2023, In: Journal for ImmunoTherapy of Cancer. 11, 7, e006921.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Computational prediction of MHC anchor locations guides neoantigen identification and prioritization

Xia, H., McMichael, J., Becker-Hapak, M., Onyeador, O. C., Buchli, R., McClain, E., Pence, P., Supabphol, S., Richters, M. M., Basu, A., Ramirez, C. A., Puig-Saus, C., Cotto, K. C., Freshour, S. L., Hundal, J., Kiwala, S., Goedegebuure, S. P., Johanns, T. M., Dunn, G. P. & Ribas, A. & 5 others, Miller, C. A., Gillanders, W. E., Fehniger, T. A., Griffith, O. L. & Griffith, M., Apr 2023, In: Science immunology. 8, 82, eabg2200.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Engineering a Novel Modular Adenoviral mRNA Delivery Platform Based on Tag/Catcher Bioconjugation

Geng, K., Rice-Boucher, P. J., Kashentseva, E. A., Dmitriev, I. P., Lu, Z. H., Goedegebuure, S. P., Gillanders, W. E. & Curiel, D. T., Nov 2023, In: Viruses. 15, 11, 2277.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

High-dimensional deconstruction of pancreatic cancer identifies tumor microenvironmental and developmental stemness features that predict survival

Storrs, E. P., Chati, P., Usmani, A., Sloan, I., Krasnick, B. A., Babbra, R., Harris, P. K., Sachs, C. M., Qaium, F., Chatterjee, D., Wetzel, C., Goedegebuure, S. P., Hollander, T., Anthony, H., Ponce, J., Khaliq, A. M., Badiyan, S., Kim, H., Denardo, D. G. & Lang, G. D. & 10 others, Cosgrove, N. D., Kushnir, V. M., Early, D. S., Masood, A., Lim, K. H., Hawkins, W. G., Ding, L., Fields, R. C., Das, K. K. & Chaudhuri, A. A., Dec 2023, In: npj Precision Oncology. 7, 1, 105.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Induction of cancer neoantigens facilitates development of clinically relevant models for the study of pancreatic cancer immunobiology

Panni, U. Y., Chen, M. Y., Zhang, F., Cullinan, D. R., Li, L., James, C. A., Zhang, X., Rogers, S., Alarcon, A., Baer, J. M., Zhang, D., Gao, F., Miller, C. A., Gong, Q., Lim, K. H., DeNardo, D. G., Goedegebuure, S. P., Gillanders, W. E. & Hawkins, W. G., Aug 2023, In: Cancer Immunology, Immunotherapy. 72, 8, p. 2813-2827 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Proteins in Tumor-Derived Plasma Extracellular Vesicles Indicate Tumor Origin

Barlin, M., Erdmann-Gilmore, P., Mudd, J. L., Zhang, Q., Seymour, R. W., Guo, Z., Miessner, J. R., Goedegebuure, S. P., Bi, Y., Osorio, O. A., Alexander-Brett, J., Li, S., Ma, C. X., Fields, R. C., Townsend, R. R. & Held, J. M., Jan 2023, In: Molecular and Cellular Proteomics. 22, 1, 100476.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Single-cell transcriptomics reveals long noncoding RNAs associated with tumor biology and the microenvironment in pancreatic cancer

Dang, H. X., Saha, D., Jayasinghe, R., Zhao, S., Coonrod, E., Mudd, J., Goedegebuure, S. P., Fields, R., Ding, L. & Maher, C. A., Dec 1 2023, In: NAR Cancer. 5, 4, zcad055.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Combination TIGIT/PD-1 blockade enhances the efficacy of neoantigen vaccines in a model of pancreatic cancer

Peng, H., Li, L., Zuo, C., Chen, M. Y., Zhang, X., Myers, N. B., Hogg, G. D., DeNardo, D. G., Goedegebuure, S. P., Hawkins, W. G. & Gillanders, W. E., Dec 8 2022, In: Frontiers in immunology. 13, 1039226.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

2021

In Silico Epitope Prediction Analyses Highlight the Potential for Distracting Antigen Immunodominance with Allogeneic Cancer Vaccines

Alston James, C., Ronning, P., Cullinan, D., Cotto, K. C., Barnell, E. K., Campbell, K. M., Skidmore, Z. L., Sanford, D. E., Peter Goedegebuure, S., Gillanders, W. E., Griffith, O. L., Hawkins, W. G. & Griffith, M., Nov 2021, In: Cancer research communications. 1, 2, p. 115-126 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Memory-like differentiation enhances NK cell responses to melanoma

Marin, N. D., Krasnick, B. A., Becker-Hapak, M., Conant, L., Goedegebuure, S. P., Berrien-Elliott, M. M., Robbins, K. J., Foltz, J. A., Foster, M., Wong, P., Cubitt, C. C., Tran, J., Wetzel, C. B., Jacobs, M., Zhou, A. Y., Russler-Germain, D., Marsala, L., Schappe, T., Fields, R. C. & Fehniger, T. A., Sep 1 2021, In: Clinical Cancer Research. 27, 17, p. 4859-4869 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

46 Scopus citations

Neoadjuvant FOLFIRINOX Therapy Is Associated with Increased Effector T Cells and Reduced Suppressor Cells in Patients with Pancreatic Cancer

Peng, H., James, C. A., Cullinan, D. R., Hogg, G. D., Mudd, J. L., Zuo, C., Takchi, R., Caldwell, K. E., Liu, J., DeNardo, D. G., Fields, R. C., Gillanders, W. E., Goedegebuure, S. P. & Hawkins, W. G., Dec 15 2021, In: Clinical Cancer Research. 27, 24, p. 6761-6771 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Neoantigen vaccine platforms in clinical development: understanding the future of personalized immunotherapy

Supabphol, S., Li, L., Goedegebuure, S. P. & Gillanders, W. E., 2021, In: Expert Opinion on Investigational Drugs. 30, 5, p. 529-541 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation

Li, L., Zhang, X., Wang, X., Kim, S. W., Herndon, J. M., Becker-Hapak, M. K., Carreno, B. M., Myers, N. B., Sturmoski, M. A., McLellan, M. D., Miller, C. A., Johanns, T. M., Tan, B. R., Dunn, G. P., Fleming, T. P., Hansen, T. H., Goedegebuure, S. P. & Gillanders, W. E., Dec 2021, In: Genome medicine. 13, 1, 56.

Research output: Contribution to journal › Article › peer-review

Open Access

37 Scopus citations

2020

Cancer vaccines: shared tumor antigens return to the spotlight

Li, L., Goedegebuure, S. P. & Gillanders, W., Dec 1 2020, In: Signal Transduction and Targeted Therapy. 5, 1, 251.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

Long non-coding RNA RAMS11 promotes metastatic colorectal cancer progression

Silva-Fisher, J. M., Dang, H. X., White, N. M., Strand, M. S., Krasnick, B. A., Rozycki, E. B., Jeffers, G. G. L., Grossman, J. G., Highkin, M. K., Tang, C., Cabanski, C. R., Eteleeb, A., Mudd, J., Goedegebuure, S. P., Luo, J., Mardis, E. R., Wilson, R. K., Ley, T. J., Lockhart, A. C. & Fields, R. C. & 1 others, Maher, C. A., Dec 1 2020, In: Nature communications. 11, 1, 2156.

Research output: Contribution to journal › Article › peer-review

Open Access

88 Scopus citations

The clonal evolution of metastatic colorectal cancer

Dang, H. X., Krasnick, B. A., White, B. S., Grossman, J. G., Strand, M. S., Zhang, J., Cabanski, C. R., Miller, C. A., Fulton, R. S., Goedegebuure, S. P., Fronick, C. C., Griffith, M., Larson, D. E., Goetz, B. D., Walker, J. R., Hawkins, W. G., Strasberg, S. M., Linehan, D. C., Lim, K. H. & Lockhart, A. C. & 5 others, Mardis, E. R., Wilson, R. K., Ley, T. J., Maher, C. A. & Fields, R. C., Jun 2020, In: Science Advances. 6, 24, eaay9691.

Research output: Contribution to journal › Article › peer-review

Open Access

48 Scopus citations

2019

Defining a murine ovarian cancer model for the evaluation of conditionally-replicative adenovirus (CRAd) virotherapy agents

González-Pastor, R., Ashshi, A. M., El-Shemi, A. G., Dmitriev, I. P., Kashentseva, E. A., Lu, Z. H., Goedegebuure, S. P., Podhajcer, O. L. & Curiel, D. T., Feb 15 2019, In: Journal of Ovarian Research. 12, 1, 18.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Precision delivery of RAS-inhibiting siRNA to KRAS driven cancer via peptide-based nanoparticles

Strand, M. S., Krasnick, B. A., Pan, H., Zhang, X., Bi, Y., Brooks, C., Wetzel, C., Sankpal, N., Fleming, T., Peter Goedegebuure, S., DeNardo, D. G., Gillanders, W. E., Hawkins, W. G., Wickline, S. A. & Fields, R. C., 2019, In: Oncotarget. 10, 46, p. 4761-4775 15 p.

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

T cell– and monocyte-specific RNA-sequencing analysis in septic and nonseptic critically ill patients and in patients with cancer

Washburn, M. L., Wang, Z., Walton, A. H., Peter Goedegebuure, S., Figueroa, D. J., van Horn, S., Grossman, J., Remlinger, K., Madsen, H., Brown, J., Srinivasan, R., Wolf, A. I., Berger, S. B., Yi, V. N., Hawkins, W. G., Fields, R. C. & Hotchkiss, R. S., Oct 1 2019, In: Journal of Immunology. 203, 7, p. 1897-1908 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

2018

Development of an adenovirus vector vaccine platform for targeting dendritic cells

Sharma, P. K., Dmitriev, I. P., Kashentseva, E. A., Raes, G., Li, L., Kim, S. W., Lu, Z. H., Arbeit, J. M., Fleming, T. P., Kaliberov, S. A., Goedegebuure, S. P., Curiel, D. T. & Gillanders, W. E., Feb 1 2018, In: Cancer gene therapy. 25, 1-2, p. 27-38 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

Recruitment of CCR2⁺ tumor associated macrophage to sites of liver metastasis confers a poor prognosis in human colorectal cancer

Grossman, J. G., Nywening, T. M., Belt, B. A., Panni, R. Z., Krasnick, B. A., DeNardo, D. G., Hawkins, W. G., Goedegebuure, S. P., Linehan, D. C. & Fields, R. C., Sep 2 2018, In: OncoImmunology. 7, 9, e1470729.

Research output: Contribution to journal › Article › peer-review

Open Access

90 Scopus citations

Targeting both tumour-associated CXCR2⁺ neutrophils and CCR2⁺ macrophages disrupts myeloid recruitment and improves chemotherapeutic responses in pancreatic ductal adenocarcinoma

Nywening, T. M., Belt, B. A., Cullinan, D. R., Panni, R. Z., Han, B. J., Sanford, D. E., Jacobs, R. C., Ye, J., Patel, A. A., Gillanders, W. E., Fields, R. C., DeNardo, D. G., Hawkins, W. G., Goedegebuure, P. & Linehan, D. C., 2018, In: Gut. 67, 6, p. 1112-1123 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

358 Scopus citations

Tumor-on-a-chip platform to investigate progression and drug sensitivity in cell lines and patient-derived organoids

Shirure, V. S., Bi, Y., Curtis, M. B., Lezia, A., Goedegebuure, M. M., Goedegebuure, S. P., Aft, R., Fields, R. C. & George, S. C., Dec 7 2018, In: Lab on a Chip. 18, 23, p. 3687-3702 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

213 Scopus citations

2017

Breast cancer neoantigens can induce CD8⁺ T-cell responses and antitumor immunity

Zhang, X., Kim, S., Hundal, J., Herndon, J. M., Li, S., Petti, A. A., Soysal, S. D., Li, L., McLellan, M. D., Hoog, J., Primeau, T., Myers, N., Vickery, T. L., Sturmoski, M., Hagemann, I. S., Miller, C. A., Ellis, M. J., Mardis, E. R., Hansen, T. & Fleming, T. P. & 2 others, Goedegebuure, S. P. & Gillanders, W. E., Jul 2017, In: Cancer immunology research. 5, 7, p. 516-523 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

67 Scopus citations

Personalized cancer vaccines: Targeting the cancer mutanome

Zhang, X., Sharma, P. K., Peter Goedegebuure, S. & Gillanders, W. E., Feb 15 2017, In: Vaccine. 35, 7, p. 1094-1100 7 p.

Research output: Contribution to journal › Article › peer-review

63 Scopus citations

The Targeted SMAC Mimetic SW IV-134 is a strong enhancer of standard chemotherapy in pancreatic cancer

Hashim, Y. M., Vangveravong, S., Sankpal, N. V., Binder, P. S., Liu, J., Goedegebuure, S. P., Mach, R. H., Spitzer, D. & Hawkins, W. G., Jan 17 2017, In: Journal of Experimental and Clinical Cancer Research. 36, 1, 14.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

2016

Conjugation to the sigma-2 ligand SV119 overcomes uptake blockade and converts dm-Erastin into a potent pancreatic cancer therapeutic

Ohman, K. A., Hashim, Y. M., Vangveravong, S., Nywening, T. M., Cullinan, D. R., Goedegebuure, S. P., Liu, J., Van Tine, B. A., Tiriac, H., Tuveson, D. A., DeNardo, D. G., Spitzer, D., Mach, R. H. & Hawkins, W. G., Jun 7 2016, In: Oncotarget. 7, 23, p. 33529-33541 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Mammaglobin-A is a target for breast cancer vaccination

Kim, S. W., Goedegebuure, P. & Gillanders, W. E., Feb 1 2016, In: OncoImmunology. 5, 2

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Membrane-proximal TRAIL species are incapable of inducing short circuit apoptosis signaling: Implications for drug development and basic cytokine biology

Tatzel, K., Kuroki, L., Dmitriev, I., Kashentseva, E., Curiel, D. T., Goedegebuure, S. P., Powell, M. A., Mutch, D. G., Hawkins, W. G. & Spitzer, D., Mar 3 2016, In: Scientific reports. 6, 22661.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: A single-centre, open-label, dose-finding, non-randomised, phase 1b trial

Nywening, T. M., Wang-Gillam, A., Sanford, D. E., Belt, B. A., Panni, R. Z., Cusworth, B. M., Toriola, A. T., Nieman, R. K., Worley, L. A., Yano, M., Fowler, K. J., Lockhart, A. C., Suresh, R., Tan, B. R., Lim, K. H., Fields, R. C., Strasberg, S. M., Hawkins, W. G., DeNardo, D. G. & Goedegebuure, S. P. & 1 others, Linehan, D. C., May 1 2016, In: The Lancet Oncology. 17, 5, p. 651-662 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

591 Scopus citations

2015

Incorporation of porcine adenovirus 4 fiber protein enhances infectivity of adenovirus vector on dendritic cells: Implications for immune-mediated cancer therapy

Wilkinson-Ryan, I., Kim, J., Kim, S., Ak, F., Dodson, L., Colonna, M., Powell, M., Mutch, D., Spitzer, D., Hansen, T., Goedegebuure, S. P., Curiel, D. & Hawkins, W., May 1 2015, In: PloS one. 10, 5, e0125851.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

2014

CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models

Zhu, Y., Knolhoff, B. L., Meyer, M. A., Nywening, T. M., West, B. L., Luo, J., Wang-Gillam, A., Goedegebuure, S. P., Linehan, D. C. & De Nardo, D. G., Jul 31 2014, In: Cancer research. 74, 18, p. 5057-5069 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

999 Scopus citations

Identification and translational validation of novel mammaglobin-A CD8 T cell epitopes

Soysal, S. D., Muenst, S., Kan-Mitchell, J., Huarte, E., Zhang, X., Wilkinson-Ryan, I., Fleming, T., Tiriveedhi, V., Mohanakumar, T., Li, L., Herndon, J., Oertli, D., Goedegebuure, S. P. & Gillanders, W. E., Sep 24 2014, In: Breast Cancer Research and Treatment. 147, 3, p. 527-537 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Novel treatment option for MUC16-positive malignancies with the targeted TRAIL-based fusion protein Meso-TR3

Garg, G., Gibbs, J., Belt, B., Powell, M. A., Mutch, D. G., Goedegebuure, P., Collins, L., Piwnica-Worms, D., Hawkins, W. G. & Spitzer, D., Jan 21 2014, In: BMC Cancer. 14, 1, 35.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Safety and preliminary evidence of biologic efficacy of a mammaglobin-A DNA vaccine in patients with stable metastatic breast cancer

Tiriveedhi, V., Tucker, N., Herndon, J., Li, J., Sturmoski, M., Ellis, M., Ma, C., Naughton, M., Lockhart, A. C., Gao, F., Fleming, T., Goedegebuure, P., Mohanakumar, T. & Gillanders, W. E., Dec 1 2014, In: Clinical Cancer Research. 20, 23, p. 5964-5975 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

72 Scopus citations

Targeted pancreatic cancer therapy with the small molecule drug conjugate SW IV-134

Hashim, Y. M., Spitzer, D., Vangveravong, S., Hornick, M. C., Garg, G., Hornick, J. R., Goedegebuure, P., Mach, R. H. & Hawkins, W. G., Jul 2014, In: Molecular Oncology. 8, 5, p. 956-967 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer

Panni, R. Z., Sanford, D. E., Belt, B. A., Mitchem, J. B., Worley, L. A., Goetz, B. D., Mukherjee, P., Wang-Gillam, A., Link, D. C., Denardo, D. G., Goedegebuure, S. P. & Linehan, D. C., May 2014, In: Cancer Immunology, Immunotherapy. 63, 5, p. 513-528 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

165 Scopus citations

2013

A phase i study of IMP321 and gemcitabine as the front-line therapy in patients with advanced pancreatic adenocarcinoma

Wang-Gillam, A., Plambeck-Suess, S., Goedegebuure, P., Simon, P. O., Mitchem, J. B., Hornick, J. R., Sorscher, S., Picus, J., Suresh, R., Lockhart, A. C., Tan, B. & Hawkins, W. G., Jun 2013, In: Investigational New Drugs. 31, 3, p. 707-713 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

86 Scopus citations

Inflammatory monocyte mobilization decreases patient survival in pancreatic cancer: A role for targeting the CCL2/CCR2 axis

Sanford, D. E., Belt, B. A., Panni, R. Z., Mayer, A., Deshpande, A. D., Carpenter, D., Mitchem, J. B., Plambeck-Suess, S. M., Worley, L. A., Goetz, B. D., Wang-Gillam, A., Eberlein, T. J., Denardo, D. G., Goedegebuure, S. P. & Linehan, D. C., Jul 1 2013, In: Clinical Cancer Research. 19, 13, p. 3404-3415 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

469 Scopus citations

Mammaglobin-A cDNA vaccination of breast cancer patients induces antigen-specific cytotoxic CD4+ICOS^hi T cells

Tiriveedhi, V., Fleming, T. P., Goedegebuure, P. S., Naughton, M., Ma, C., Lockhart, C., Gao, F., Gillanders, W. E. & Mohanakumar, T., Feb 2013, In: Breast Cancer Research and Treatment. 138, 1, p. 109-118 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

49 Scopus citations

Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses

Mitchem, J. B., Brennan, D. J., Knolhoff, B. L., Belt, B. A., Zhu, Y., Sanford, D. E., Belaygorod, L., Carpenter, D., Collins, L., Piwnica-Worms, D., Hewitt, S., Udupi, G. M., Gallagher, W. M., Wegner, C., West, B. L., Wang-Gillam, A., Goedegebuure, P., Linehan, D. C. & DeNardo, D. G., Feb 1 2013, In: Cancer research. 73, 3, p. 1128-1141 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

786 Scopus citations

2012

Cross-dressed CD8α⁺/CD103⁺ dendritic cells prime CD8⁺ T cells following vaccination

Li, J., Kim, S., Herndon, J. M., Goedegebuure, P., Belt, B. A., Satpathy, A. T., Fleming, T. P., Hansen, T. H., Murphy, K. M. & Gillanders, W. E., Jul 31 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 31, p. 12716-12721 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

64 Scopus citations

Lysosomal membrane permeabilization is an early event in sigma-2 receptor ligand mediated cell death in pancreatic cancer

Hornick, J. R., Vangveravong, S., Spitzer, D., Abate, C., Berardi, F., Goedegebuure, P., MacH, R. H. & Hawkins, W. G., 2012, In: Journal of Experimental and Clinical Cancer Research. 31, 1, 41.

Research output: Contribution to journal › Article › peer-review

Open Access

67 Scopus citations

Pancreatic adenocarcinoma induces bone marrow mobilization of myeloid-derived suppressor cells which promote primary tumor growth

Porembka, M. R., Mitchem, J. B., Belt, B. A., Hsieh, C. S., Lee, H. M., Herndon, J., Gillanders, W. E., Linehan, D. C. & Goedegebuure, P., Sep 2012, In: Cancer Immunology, Immunotherapy. 61, 9, p. 1373-1385 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

223 Scopus citations

Regulating mammalian target of rapamycin to tune vaccination-induced CD8 ⁺ T cell responses for tumor immunity

Li, Q., Rao, R., Vazzana, J., Goedegebuure, P., Odunsi, K., Gillanders, W. & Shrikant, P. A., Apr 1 2012, In: Journal of Immunology. 188, 7, p. 3080-3087 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

73 Scopus citations

Therapeutic targeting of pancreatic cancer utilizing sigma-2 ligands

Hornick, J. R., Spitzer, D., Goedegebuure, P., MacH, R. H. & Hawkins, W. G., Sep 2012, In: Surgery (United States). 152, 3 SUPPL., p. S152-S156

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Use of multifunctional sigma-2 receptor ligand conjugates to trigger cancer-selective cell death signaling

Spitzer, D., Simon, P. O., Kashiwagi, H., Xu, J., Zeng, C., Vangveravong, S., Zhou, D., Chang, K., McDunn, J. E., Hornick, J. R., Goedegebuure, P., Hotchkiss, R. S., Mach, R. H. & Hawkins, W. G., Jan 1 2012, In: Cancer research. 72, 1, p. 201-209 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

40 Scopus citations

S. Peter Goedegebuure

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