Research output per year
Research output per year
Personal profile
Research interests
My lab is currently focused on elucidating the structures and functions of microtubule associated proteins and microtubule-based macromolecular assemblies such as the cilia. We use high-resolution cryo-electron microscopy (cryo-EM) as our main structural technique, in combination with other genetic and biochemical approaches.
Available to Mentor:
- PhD/MSTP Students
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Evolutionary adaptations of doublet microtubules in trypanosomatid parasites
Doran, M. H., Niu, Q., Zeng, J., Beneke, T., Smith, J., Ren, P., Fochler, S., Coscia, A., Höög, J. L., Meleppattu, S., Lishko, P. V., Wheeler, R. J., Gluenz, E., Zhang, R. & Brown, A., Mar 14 2025, In: Science (New York, N.Y.). 387, 6739, p. eadr5507Research output: Contribution to journal › Article › peer-review
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Structural diversity of axonemes across mammalian motile cilia
Leung, M. R., Sun, C., Zeng, J., Anderson, J. R., Niu, Q., Huang, W., Noteborn, W. E. M., Brown, A., Zeev-Ben-Mordehai, T. & Zhang, R., Jan 30 2025, In: Nature. 637, 8048, p. 1170-1177 8 p., 5727.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
TRiC Is a Structural Component of Mammalian Sperm Axonemes
Brown, A., Leung, M. R., Zeev-Ben-Mordehai, T. & Zhang, R., 2025, (Accepted/In press) In: Cytoskeleton.Research output: Contribution to journal › Article › peer-review
Open Access -
Undocking of an extensive ciliary network induces proteostasis and cell fate switching resulting in severe primary ciliary dyskinesia
Brody, S. L., Pan, J., Huang, T., Xu, J., Xu, H., Koenitizer, J. R., Brennan, S. K., Nanjundappa, R., Saba, T. G., Rumman, N., Berical, A., Hawkins, F. J., Wang, X., Zhang, R., Mahjoub, M. R., Horani, A. & Dutcher, S. K., Jan 29 2025, In: Science translational medicine. 17, 783, eadp5173.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Automated model building and protein identification in cryo-EM maps
Jamali, K., Käll, L., Zhang, R., Brown, A., Kimanius, D. & Scheres, S. H. W., Apr 11 2024, In: Nature. 628, 8007, p. 450-457 8 p.Research output: Contribution to journal › Article › peer-review
123 Scopus citations