Rui Tang

2025

Cancer-targeted pro-theranostic bi-metallic organocoordination nanoparticles

Huang, H., Fang, L., Wansapura, J., Prior, J. L., Manion, B., Xu, B., Hongsermeier, C., Gamadia, N., Blasi, N., Tang, R., Egbulefu, C., Shokeen, M., Quirk, J. D. & Achilefu, S., 2025, In: Theranostics. 15, 4, p. 1205-1220 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Imaging Peripheral Nerves In Vivo with CT Neurogram Using Novel 2,4,6-Tri-Iodinated Lidocaine Contrast Agent

Tang, R., Perez, R., Brogan, D. M., Berezin, M. Y. & McCarthy, J. E., Apr 2025, In: Bioengineering. 12, 4, 422.

Research output: Contribution to journal › Article › peer-review

Open Access

2024

Development of New CD38 Targeted Peptides for Cancer Imaging

Zheleznyak, A., Tang, R., Duncan, K., Manion, B., Liang, K., Xu, B., Vanover, A., Ghai, A., Prior, J., Lees, S., Achilefu, S., Kelly, K. & Shokeen, M., Aug 2024, In: Molecular Imaging and Biology. 26, 4, p. 738-752 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

2023

Gold nanoparticle-enhanced X-ray microtomography of the rodent reveals region-specific cerebrospinal fluid circulation in the brain

Pan, S., Yang, P. H., DeFreitas, D., Ramagiri, S., Bayguinov, P. O., Hacker, C. D., Snyder, A. Z., Wilborn, J., Huang, H., Koller, G. M., Raval, D. K., Halupnik, G. L., Sviben, S., Achilefu, S., Tang, R., Haller, G., Quirk, J. D., Fitzpatrick, J. A. J., Esakky, P. & Strahle, J. M., Dec 2023, In: Nature communications. 14, 1, 453.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

2022

Analysis of Stable Chelate-free Gadolinium Loaded Titanium Dioxide Nanoparticles for MRI-Guided Radionuclide Stimulated Cancer Treatment

Fang, L., Huang, H., Quirk, J. D., Zheng, J., Shen, D., Manion, B., Mixdorf, M., Karmakar, P., Sudlow, G. P., Tang, R. & Achilefu, S., Aug 2022, In: Current Analytical Chemistry. 18, 7, p. 826-835 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

2021

Non-invasive monitoring of arthritis treatment response via targeting of tyrosine-phosphorylated annexin A2 in chondrocytes

Tsen, S. W. D., Springer, L. E., Sharmah Gautam, K., Tang, R., Liang, K., Sudlow, G., Kucharski, A., Pham, C. T. N. & Achilefu, S., Dec 2021, In: Arthritis Research and Therapy. 23, 1, 265.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Tryptophan fluorescence and machine learning to study the aggressiveness of prostate cancer cell lines: A pilot study

Xue, J., Mo, H., Tian, Y., Tang, R. & Wu, B., Jan 1 2021, Biophotonics, Tryptophan and Disease. Elsevier, p. 173-183 11 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

3 Scopus citations

2020

Effects of core titanium crystal dimension and crystal phase on ROS generation and tumour accumulation of transferrin coated titanium dioxide nanoaggregates

Lane, D. D., Black, K. C. L., Raliya, R., Reed, N., Kotagiri, N., Gilson, R., Tang, R., Biswas, P. & Achilefu, S., Jun 23 2020, In: RSC Advances. 10, 40, p. 23759-23766 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Osteotropic Radiolabeled Nanophotosensitizer for Imaging and Treating Multiple Myeloma

Tang, R., Zheleznyak, A., Mixdorf, M., Ghai, A., Prior, J., Black, K. C. L., Shokeen, M., Reed, N., Biswas, P. & Achilefu, S., Apr 28 2020, In: ACS nano. 14, 4, p. 4255-4264 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

Reduced Nhe1 (Na⁺-H⁺Exchanger-1) Function Protects ApoE-Deficient Mice from Ang II (Angiotensin II)-Induced Abdominal Aortic Aneurysms

Liu, C. L., Liu, X., Wang, Y., Deng, Z., Liu, T., Sukhova, G. K., Wojtkiewicz, G. R., Tang, R., Zhang, J. Y., Achilefu, S., Nahrendorf, M., Libby, P., Wang, X. & Shi, G. P., Jul 1 2020, In: Hypertension. 76, 1, p. 87-100 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Selective imaging of solid tumours via the calcium-dependent high-affinity binding of a cyclic octapeptide to phosphorylated Annexin A2

Shen, D., Xu, B., Liang, K., Tang, R., Sudlow, G. P., Egbulefu, C., Guo, K., Som, A., Gilson, R., Maji, D., Mondal, S., Habimana-Griffin, L. M., Akers, W. J., Li, S., Liu, Y., Bloch, S., Kurkure, S., Nussinov, Z., Seidel, A. & Tsen, S. W. D. & 1 others, Achilefu, S., Mar 1 2020, In: Nature Biomedical Engineering. 4, 3, p. 298-313 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

Ultrabright fluorescent nanoscale labels for the femtomolar detection of analytes with standard bioassays

Luan, J., Seth, A., Gupta, R., Wang, Z., Rathi, P., Cao, S., Gholami Derami, H., Tang, R., Xu, B., Achilefu, S., Morrissey, J. J. & Singamaneni, S., May 1 2020, In: Nature Biomedical Engineering. 4, 5, p. 518-530 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

141 Scopus citations

2019

3D Printing of Poloxamer 407 Nanogel Discs and Their Applications in Adjuvant Ovarian Cancer Therapy

Cho, H., Jammalamadaka, U., Tappa, K., Egbulefu, C., Prior, J., Tang, R. & Achilefu, S., Feb 4 2019, In: Molecular Pharmaceutics. 16, 2, p. 552-560 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

41 Scopus citations

Electrospray Functionalization of Titanium Dioxide Nanoparticles with Transferrin for Cerenkov Radiation Induced Cancer Therapy

Reed, N. A., Raliya, R., Tang, R., Xu, B., Mixdorf, M., Achilefu, S. & Biswas, P., Mar 18 2019, In: ACS Applied Bio Materials. 2, 3, p. 1141-1147 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Na⁺-H⁺ exchanger 1 determines atherosclerotic lesion acidification and promotes atherogenesis

Liu, C. L., Zhang, X., Liu, J., Wang, Y., Sukhova, G. K., Wojtkiewicz, G. R., Liu, T., Tang, R., Achilefu, S., Nahrendorf, M., Libby, P., Guo, J., Zhang, J. Y. & Shi, G. P., Dec 1 2019, In: Nature communications. 10, 1, 3978.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Shape-Dependent Biodistribution of Biocompatible Silk Microcapsules

Cao, S., Tang, R., Sudlow, G., Wang, Z., Liu, K. K., Luan, J., Tadepalli, S., Seth, A., Achilefu, S. & Singamaneni, S., Feb 6 2019, In: ACS Applied Materials and Interfaces. 11, 5, p. 5499-5508 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Trafficking of a single photosensitizing molecule to different intracellular organelles demonstrates effective hydroxyl radical-mediated photodynamic therapy in the endoplasmic reticulum

Gilson, R. C., Tang, R., Gautam, K. S., Grabowska, D. & Achilefu, S., May 15 2019, In: Bioconjugate Chemistry. 30, 5, p. 1451-1458 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

2018

Perfusion-based fluorescence imaging method delineates diverse organs and identifies multifocal tumors using generic near-infrared molecular probes

Miller, J., Wang, S. T., Orukari, I., Prior, J., Sudlow, G., Su, X., Liang, K., Tang, R., Hillman, E. M. C., Weilbaecher, K. N., Culver, J. P., Berezin, M. Y. & Achilefu, S., Apr 2018, In: Journal of Biophotonics. 11, 4, e201700232.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Ultrasmall visible-to-near-infrared emitting silver-sulfide quantum dots for cancer detection and imaging

Tang, R., Xu, B., Shen, D., Sudlow, G. & Achilefu, S., 2018, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications X. Achilefu, S. & Raghavachari, R. (eds.). SPIE, 105080G. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10508).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

2017

Bolus injections of novel thrombogenic site-targeted fusion proteins comprising annexin-V and Kunitz protease inhibitors attenuate intimal hyperplasia after balloon angioplasty

Yeh, Y. H., Chang, S. H., Chen, S. Y., Wen, C. J., Wei, F. C., Tang, R., Achilefu, S., Wun, T. C. & Chen, W. J., Aug 1 2017, In: International Journal of Cardiology. 240, p. 339-346 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Fluorescence Cancer Imaging

Black, K., Tang, R., Egbulefu, C., Tsen, S. W. D., Akers, W. J. & Achilefu, S., Jun 22 2017, Fluorescent Sensors and Imaging Agents. Elsevier Inc., Vol. 8. p. 469-490 22 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

Nanophotosensitive drugs for light-based cancer therapy: What does the future hold?

Tang, R., Habimana-Griffin, L. M. M., Lane, D. D., Egbulefu, C. & Achilefu, S., May 2017, In: Nanomedicine. 12, 10, p. 1101-1105 5 p.

Research output: Contribution to journal › Comment/debate

Open Access

17 Scopus citations

Novel injury site targeted fusion protein comprising annexin v and kunitz inhibitor domains ameliorates ischemia-reperfusion injury and promotes survival of ischemic rat abdominal skin flaps

Shyu, V. B. H., Hsu, C. E., Wen, C. J., Wun, T. C., Tang, R., Achilefu, S., Wei, F. C. & Cheng, H. Y., 2017, In: Annals of Plastic Surgery. 78, 3, p. S129-S134

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

2016

Proof-of-Concept of Polymeric Sol-Gels in Multi-Drug Delivery and Intraoperative Image-Guided Surgery for Peritoneal Ovarian Cancer

McKenzie, M., Betts, D., Suh, A., Bui, K., Tang, R., Liang, K., Achilefu, S., Kwon, G. S. & Cho, H., Sep 1 2016, In: Pharmaceutical Research. 33, 9, p. 2298-2306 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

2015

Protonation and Trapping of a Small pH-Sensitive Near-Infrared Fluorescent Molecule in the Acidic Tumor Environment Delineate Diverse Tumors in Vivo

Gilson, R. C., Tang, R., Som, A., Klajer, C., Sarder, P., Sudlow, G. P., Akers, W. J. & Achilefu, S., Oct 21 2015, In: Molecular Pharmaceutics. 12, 12, p. 4237-4246 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

Tunable ultrasmall visible-to-extended near-infrared emitting silver sulfide quantum dots for integrin-targeted cancer imaging

Tang, R., Xue, J., Xu, B., Shen, D., Sudlow, G. P. & Achilefu, S., Jan 27 2015, In: ACS nano. 9, 1, p. 220-230 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

188 Scopus citations

2014

Probing distance-dependent plasmon-enhanced near-infrared fluorescence using polyelectrolyte multilayers as dielectric spacers

Gandra, N., Portz, C., Tian, L., Tang, R., Xu, B., Achilefu, S. & Singamaneni, S., Jan 13 2014, In: Angewandte Chemie - International Edition. 53, 3, p. 866-870 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

84 Scopus citations

Synthesis of dye conjugates to visualize the cancer cells using fluorescence microscopy

Pu, Y., Tang, R., Xue, J., Wang, W. B., Xu, B. & Achilefu, S., Apr 10 2014, In: Applied Optics. 53, 11, p. 2345-2351 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

Ultrabright NIR fluorescent mesoporous silica nanoparticles

Palantavida, S., Tang, R., Sudlow, G. P., Akers, W. J., Achilefu, S. & Sokolov, I., May 28 2014, In: Journal of Materials Chemistry B. 2, 20, p. 3107-3114 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

51 Scopus citations

2013

All-near-infrared multiphoton microscopy interrogates intact tissues at deeper imaging depths than conventional single-and two-photon near-infrared excitation microscopes

Sarder, P., Yazdanfar, S., Akers, W. J., Tang, R., Sudlow, G. P., Egbulefu, C. & Achilefu, S., Oct 2013, In: Journal of biomedical optics. 18, 10, 106012.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Dual fluorescent molecular substrates selectively report the activation, sustainability and reversibility of cellular PKB/Akt activity

Shen, D., Bai, M., Tang, R., Xu, B., Ju, X., Pestell, R. G. & Achilefu, S., 2013, In: Scientific reports. 3, 1697.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Investigation of native fluorescence spectral difference among prostate cancer cell lines with different risk levels

Pu, Y., Xue, J., Xu, B., Wang, W., Gu, Y., Tang, R., Achilefu, S., Ackerstaff, E., Koutcher, J. A. & Alfano, R. R., 2013, Optical Biopsy XI. 85770X. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 8577).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

5 Scopus citations

Native fluorescence spectroscopy reveals spectral differences among prostate cancer cell lines with different risk levels

Pu, Y., Xue, J., Wang, W., Xu, B., Gu, Y., Tang, R., Ackerstaff, E., Koutcher, J. A., Achilefu, S. & Alfano, R. R., Aug 2013, In: Journal of biomedical optics. 18, 8, 087002.

Research output: Contribution to journal › Article › peer-review

Open Access

41 Scopus citations

Near-infrared fluorescence goggle system with complementary metal-oxide-semiconductor imaging sensor and see-through display

Liu, Y., Njuguna, R., Matthews, T., Akers, W. J., Sudlow, G. P., Mondal, S., Tang, R., Gruev, V. & Achilefu, S., 2013, In: Journal of biomedical optics. 18, 10, 101303.

Research output: Contribution to journal › Article › peer-review

Open Access

50 Scopus citations

Pyrazole-substituted near-infrared cyanine dyes exhibit pH-dependent fluorescence lifetime properties

Lee, H., Berezin, M. Y., Tang, R., Zhegalova, N. & Achilefu, S., Mar 2013, In: Photochemistry and Photobiology. 89, 2, p. 326-331 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Synthesize dye-bioconjugates to visualize cancer cells using fluorescence microscopy

Pu, Y., Tang, R., Xue, J., Wang, W. B., Xu, B., Shen, D., Bloch, S., Zhou, M., Achilefu, S. & Alfano, R. R., 2013, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XI. 85871Z. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 8587).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

The search for universal optical molecular imaging probes for tumors

Shen, D., Liu, Y., Liang, K., Tang, R., Charanya, T., Xu, B., Sudlow, G., Akers, W. & Achilefu, S., 2013, Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013. Optical Society of America (OSA), p. JW4A.4 (Optical Molecular Probes, Imaging and Drug Delivery, OMP 2013).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

The search for universal optical molecular imaging probes for tumors

Shen, D., Liu, Y., Liang, K., Tang, R., Charanya, T., Xu, B., Sudlow, G., Akers, W. & Achilefu, S., 2013, Bio-Optics: Design and Application, BODA 2013. p. JW4A.4 (Bio-Optics: Design and Application, BODA 2013).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

The search for universal optical molecular imaging probes for tumors

Shen, D., Liu, Y., Liang, K., Tang, R., Charanya, T., Xu, B., Sudlow, G., Akers, W. & Achilefu, S., 2013, Optical Trapping Applications, OTA 2013. p. JW4A.4 (Optical Trapping Applications, OTA 2013).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2012

Bound 1D excitons in single CdSe quantum wires

Wayman, V. L., Morrison, P. J., Wang, F., Tang, R., Buhro, W. E. & Loomis, R. A., Sep 20 2012, In: Journal of Physical Chemistry Letters. 3, 18, p. 2627-2632 6 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Induction of pH sensitivity on the fluorescence lifetime of quantum dots by NIR fluorescent dyes

Tang, R., Lee, H. & Achilefu, S., Mar 14 2012, In: Journal of the American Chemical Society. 134, 10, p. 4545-4548 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

82 Scopus citations

2011

Near-infrared pH-activatable fluorescent probes for imaging primary and metastatic breast tumors

Lee, H., Akers, W., Bhushan, K., Bloch, S., Sudlow, G., Tang, R. & Achilefu, S., Apr 20 2011, In: Bioconjugate Chemistry. 22, 4, p. 777-784 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

188 Scopus citations

2009

Exciton localization and migration in individual CdSe quantum wires at low temperatures

Glennon, J. J., Tang, R., Buhro, W. E., Loomis, R. A., Bussian, D. A., Htoon, H. & Klimov, V. I., Aug 11 2009, In: Physical Review B - Condensed Matter and Materials Physics. 80, 8, 081303.

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Spectroscopic identification of tri-n-octylphosphine oxide (TOPO) impurities and elucidation of their roles in cadmium selenide quantum-wire growth

Wang, F., Tang, R., Kao, J. L. F., Dingman, S. D. & Buhro, W. E., Apr 8 2009, In: Journal of the American Chemical Society. 131, 13, p. 4983-4994 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

141 Scopus citations

2008

Size- and shape-controlled synthesis of bismuth nanoparticles

Wang, F., Tang, R., Yu, H., Gibbons, P. C. & Buhro, W. E., Jun 10 2008, In: Chemistry of Materials. 20, 11, p. 3656-3662 7 p.

Research output: Contribution to journal › Article › peer-review

156 Scopus citations

Spectroscopy and dynamics of multiexciton states in single CdSe quantum wires

Loomis, R. A., Glennon, J. J., Buchanan, L. E., Tang, R. & Buhro, W. E., Dec 1 2008, American Chemical Society - 235th National Meeting, Abstracts of Scientific Papers. (ACS National Meeting Book of Abstracts).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

The trouble with TOPO; identification of adventitious impurities beneficial to the growth of cadmium selenide quantum dots, rods, and wires

Wang, F., Tang, R. & Buhro, W. E., Oct 1 2008, In: Nano Letters. 8, 10, p. 3521-3524 4 p.

Research output: Contribution to journal › Article › peer-review

171 Scopus citations

2007

Solution-based growth and structural characterization of homo- and heterobranched semiconductor nanowires

Dong, A., Tang, R. & Buhro, W. E., Oct 10 2007, In: Journal of the American Chemical Society. 129, 40, p. 12254-12262 9 p.

Research output: Contribution to journal › Article › peer-review

109 Scopus citations

Synchronous photoluminescence intermittency (blinking) along whole semiconductor quantum wires

Glennon, J. J., Tang, R., Buhro, W. E. & Loomis, R. A., Nov 1 2007, In: Nano Letters. 7, 11, p. 3290-3295 6 p.

Research output: Contribution to journal › Article › peer-review

75 Scopus citations

2006

Solution-liquid-solid growth of semiconductor nanowires

Wang, F., Dong, A., Sun, J., Tang, R., Yu, H. & Buhro, W. E., Sep 18 2006, In: Inorganic Chemistry. 45, 19, p. 7511-7521 11 p.

Research output: Contribution to journal › Review article › peer-review

317 Scopus citations

Rui Tang

Research output

Search results