Search results

  • 2015

    HER2-mutated breast cancer responds to treatment with single-agent neratinib, a second-generation HER2/EGFR tyrosine kinase inhibitor

    Ben-Baruch, N. E., Bose, R., Kavuri, S. M., Ma, C. X. & Ellis, M. J., Sep 1 2015, In: JNCCN Journal of the National Comprehensive Cancer Network. 13, 9, p. 1061-1064 4 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    76 Scopus citations
  • Statistically identifying tumor suppressors and oncogenes from pan-cancer genome-sequencing data

    Kumar, R. D., Searleman, A. C., Swamidass, S. J., Griffith, O. L. & Bose, R., May 25 2015, In: Bioinformatics. 31, 22, p. 3561-3568 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    46 Scopus citations
  • 2014

    Genomic events in breast cancer progression

    Goncalves, R., Cakar, B., Bose, R., Ma, C. X. & Ellis, M. J., May 14 2014, Diseases of the Breast: Fifth Edition. Wolters Kluwer Health Adis (ESP)

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

  • Tissue phosphoproteomics with PolyMAC identifies potential therapeutic targets in a transgenic mouse model of HER2 positive breast cancer

    Searleman, A. C., Iliuk, A. B., Collier, T. S., Chodosh, L. A., Tao, W. A. & Bose, R., Dec 1 2014, In: Electrophoresis. 35, 24, p. 3463-3469 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    12 Scopus citations
  • 2013

    Activating HER2 mutations in HER2 gene amplification negative breast cancer

    Bose, R., Kavuri, S. M., Searleman, A. C., Shen, W., Shen, D., Koboldt, D. C., Monsey, J., Goel, N., Aronson, A. B., Li, S., Ma, C. X., Ding, L., Mardis, E. R. & Ellis, M. J., 2013, In: Cancer discovery. 3, 2, p. 224-237 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    690 Scopus citations
  • A neu view of invasive lobular breast cancer

    Bose, R., Jul 1 2013, In: Clinical Cancer Research. 19, 13, p. 3331-3333 3 p.

    Research output: Contribution to journalShort surveypeer-review

    Open Access
    11 Scopus citations
  • Carboxyl group footprinting mass spectrometry and molecular dynamics identify key interactions in the HER2-HER3 receptor tyrosine kinase interface

    Collier, T. S., Diraviyam, K., Monsey, J., Shen, W., Sept, D. & Bose, R., Aug 30 2013, In: Journal of Biological Chemistry. 288, 35, p. 25254-25264 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    31 Scopus citations
  • DGIdb: Mining the druggable genome

    Griffith, M., Griffith, O. L., Coffman, A. C., Weible, J. V., Mcmichael, J. F., Spies, N. C., Koval, J., Das, I., Callaway, M. B., Eldred, J. M., Miller, C. A., Subramanian, J., Govindan, R., Kumar, R. D., Bose, R., Ding, L., Walker, J. R., Larson, D. E., Dooling, D. J. & Smith, S. M. & 3 others, Ley, T. J., Mardis, E. R. & Wilson, R. K., Dec 2013, In: Nature Methods. 10, 12, p. 1209-1210 2 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    399 Scopus citations
  • Endocrine-Therapy-Resistant ESR1 Variants Revealed by Genomic Characterization of Breast-Cancer-Derived Xenografts

    Li, S., Shen, D., Shao, J., Crowder, R., Liu, W., Prat, A., He, X., Liu, S., Hoog, J., Lu, C., Ding, L., Griffith, O. L., Miller, C., Larson, D., Fulton, R. S., Harrison, M., Mooney, T., McMichael, J. F., Luo, J. & Tao, Y. & 35 others, Goncalves, R., Schlosberg, C., Hiken, J. F., Saied, L., Sanchez, C., Giuntoli, T., Bumb, C., Cooper, C., Kitchens, R. T., Lin, A., Phommaly, C., Davies, S. R., Zhang, J., Kavuri, M. S., McEachern, D., Dong, Y. Y., Ma, C., Pluard, T., Naughton, M., Bose, R., Suresh, R., McDowell, R., Michel, L., Aft, R., Gillanders, W., DeSchryver, K., Wilson, R. K., Wang, S., Mills, G. B., Gonzalez-Angulo, A., Edwards, J. R., Maher, C., Perou, C. M., Mardis, E. R. & Ellis, M. J., Sep 26 2013, In: Cell Reports. 4, 6, p. 1116-1130 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    516 Scopus citations
  • Incorporating genomics into breast cancer clinical trials and care

    Tabchy, A., Ma, C. X., Bose, R. & Ellis, M. J., Dec 1 2013, In: Clinical Cancer Research. 19, 23, p. 6371-6379 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    17 Scopus citations
  • Prioritizing Potentially Druggable Mutations with dGene: An Annotation Tool for Cancer Genome Sequencing Data

    Kumar, R. D., Chang, L. W., Ellis, M. J. & Bose, R., Jun 27 2013, In: PloS one. 8, 6, e67980.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    26 Scopus citations
  • Quantitative proteomics with siRNA screening identifies novel mechanisms of trastuzumab resistance in HER2 amplified breast cancers

    Boyer, A. P., Collier, T. S., Vidavsky, I. & Bose, R., Jan 2013, In: Molecular and Cellular Proteomics. 12, 1, p. 180-193 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    47 Scopus citations
  • Using multigene tests to select treatment for early-stage breast cancer

    Goncalves, R. & Bose, R., Feb 1 2013, In: JNCCN Journal of the National Comprehensive Cancer Network. 11, 2, p. 174-182 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    55 Scopus citations
  • 2012

    Comprehensive genomic characterization of squamous cell lung cancers

    Hammerman, P. S., Voet, D., Lawrence, M. S., Voet, D., Jing, R., Cibulskis, K., Sivachenko, A., Stojanov, P., McKenna, A., Lander, E. S., Gabriel, S., Getz, G., Imielinski, M., Helman, E., Hernandez, B., Pho, N. H., Meyerson, M., Chu, A., Hye-Chun, J. E. & Mungall, A. J. & 316 others, Pleasance, E., Robertson, A. G., Sipahimalani, P., Stoll, D., Balasundaram, M., Birol, I., Butterfield, Y. S. N., Chuah, E., Coope, R. J. N., Corbett, R., Dhalla, N., Guin, R., He, A., Hirst, C., Hirst, M., Holt, R. A., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Mungall, K., Nip, K. M., Olshen, A., Schein, J. E., Slobodan, J. R., Tam, A., Thiessen, N., Varhol, R., Zeng, T., Zhao, Y., Jones, S. J. M., Marra, M. A., Saksena, G., Cherniack, A. D., Schumacher, S. E., Tabak, B., Carter, S. L., Nguyen, H., Onofrio, R. C., Crenshaw, A., Ardlie, K., Beroukhim, R., Winckler, W., Protopopov, A., Zhang, J., Hadjipanayis, A., Lee, S., Xi, R., Yang, L., Ren, X., Zhang, H., Shukla, S., Chen, P. C., Haseley, P., Lee, E., Chin, L., Park, P. J., Kucherlapati, R., Socci, N. D., Liang, Y., Schultz, N., Borsu, L., Lash, A. E., Viale, A., Sander, C., Ladanyi, M., Auman, J. T., Hoadley, K. A., Wilkerson, M. D., Shi, Y., Liquori, C., Meng, S., Li, L., Turman, Y. J., Topal, M. D., Tan, D., Waring, S., Buda, E., Walsh, J., Jones, C. D., Mieczkowski, P. A., Singh, D., Wu, J., Gulabani, A., Dolina, P., Bodenheimer, T., Hoyle, A. P., Simons, J. V., Soloway, M. G., Stuart, J., Mose, L. E., Jefferys, S. R., Balu, S., O'Connor, B. D., Chiang, D., Liu, J., Chiang, D. Y., Hayes, D. N., Perou, C. M., Cope, L., Weisenberger, D., Danilova, L., Weisenberger, D. J., Maglinte, D. T., Pan, F., Van Den Berg, D. J., Triche, T., Herman, J. G., Baylin, S. B., Laird, P. W., Noble, M., Gehlenborg, N., DiCara, D., Zhang, J., Wu, C. J., Liu, S. Y., Zou, L., Lin, P., Cho, J., Nazaire, M. D., Robinson, J., Thorvaldsdottir, H., Mesirov, J., Sinha, R., Ciriello, G., Cerami, E., Gross, B., Jacobsen, A., Gao, J., Aksoy, B. A., Weinhold, N., Ramirez, R., Taylor, B. S., Antipin, Y., Reva, B., Mo, Q., Seshan, V., Paik, P. K., Akbani, R., Zhang, N., Broom, B. M., Casasent, T., Unruh, A., Wakefield, C., Cason, R. C., Baggerly, K. A., Weinstein, J. N., Haussler, D., Benz, C. C., Stuart, J. M., Zhu, J., Szeto, C., Scott, G. K., Yau, C., Ng, S., Goldstein, T., Waltman, P., Sokolov, A., Collisson, E., Ellrott, K., Collisson, E. A., Zerbino, D., Ma, S., Craft, B., Du, Y., Cabanski, C., Walter, V., Marron, J. S., Liu, Y., Wang, K., Prins, J. F., Creighton, C. J., Zhang, Y., Travis, W. D., Rekhtman, N., Yi, J., Aubry, M. C., Cheney, R., Dacic, S., Flieder, D., Funkhouser, W., Illei, P., Myers, J., Tsao, M. S., Penny, R., Mallery, D., Shelton, T., Hatfield, M., Morris, S., Yena, P., Shelton, C., Sherman, M., Paulauskis, J., Govindan, R., Azodo, I., Beer, D., Bose, R., Byers, L. A., Carbone, D., Chang, L. W., Chun, E., Ding, L., Heymach, J., Ida, C., Johnson, B., Jurisica, I., Kaufman, J., Kosari, F., Kwiatkowski, D., Maher, C. A., Pao, W., Peifer, M., Robertson, G., Rusch, V., Siegfried, J., Sougnez, C., Thomas, R. K., Tomaszek, S., Vaske, C., Wheeler, D., Wigle, D. A., Wilks, C., Zhang, J. J., Jensen, M. A., Sfeir, R., Kahn, A. B., Chu, A. L., Kothiyal, P., Wang, Z., Snyder, E. E., Pontius, J., Pihl, T. D., Backus, M., Walton, J., Baboud, J., Berton, D. L., Nicholls, M. C., Srinivasan, D., Raman, R., Girshik, S., Kigonya, P. A., Alonso, S., Sanbhadti, R. N., Barletta, S. P., Greene, J. M., Pot, D. A., Bandarchi-Chamkhaleh, B., Boyd, J., Weaver, J., Azodo, I. A., Tomaszek, S. C., Yang, P., Brock, M. V., Rogers, K., Rutledge, M., Brown, T., Lee, B., Shin, J., Trusty, D., Dhir, R., Siegfried, J. M., Potapova, O., Fedosenko, K. V., Zakowski, M., Nemirovich-Danchenko, E., Iacocca, M. V., Brown, J., Rabeno, B., Czerwinski, C., Petrelli, N., Fan, Z., Todaro, N., Eckman, J., Rathmell, W. K., Thorne, L. B., Huang, M., Boice, L., Hill, A., Curley, E., Morrison, C., Gaudioso, C., Bartlett, J. M. S., Kodeeswaran, S., Zanke, B., Sekhon, H., David, K., Juhl, H., Le, X. V., Kohl, B., Thorp, R., Tien, N. V., Bang, N. V., Sussman, H., Phu, B. D., Hajek, R., Hung, N. P., Khan, K. Z., Muley, T., Mills Shaw, K. R., Sheth, M., Yang, L., Demchok, J. A., Davidsen, T., Buetow, K., Eley, G., Ferguson, M., Dillon, L. A. L., Schaefer, C., Guyer, M. S., Ozenberger, B. A., Palchik, J. D., Peterson, J., Sofia, H. J., Thomson, E., Johnson, B. E. & Shen, R., Sep 27 2012, In: Nature. 489, 7417, p. 519-525 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3252 Scopus citations
  • Comprehensive molecular portraits of human breast tumours

    Koboldt, D. C., Fulton, R. S., McLellan, M. D., Schmidt, H., Kalicki-Veizer, J., McMichael, J. F., Fulton, L. L., Dooling, D. J., Ding, L., Mardis, E. R., Wilson, R. K., Ally, A., Balasundaram, M., Butterfield, Y. S. N., Carlsen, R., Carter, C., Chu, A., Chuah, E., Chun, H. J. E. & Coope, R. J. N. & 323 others, Dhalla, N., Guin, R., Hirst, C., Hirst, M., Holt, R. A., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Mungall, A. J., Pleasance, E., Robertson, A. G., Schein, J. E., Shafiei, A., Sipahimalani, P., Slobodan, J. R., Stoll, D., Tam, A., Thiessen, N., Varhol, R. J., Wye, N., Zeng, T., Zhao, Y., Birol, I., Jones, S. J. M., Marra, M. A., Cherniack, A. D., Saksena, G., Onofrio, R. C., Pho, N. H., Carter, S. L., Schumacher, S. E., Tabak, B., Hernandez, B., Gentry, J., Nguyen, H., Crenshaw, A., Ardlie, K., Beroukhim, R., Winckler, W., Getz, G., Gabriel, S. B., Meyerson, M., Chin, L., Kucherlapati, R., Hoadley, K. A., Auman, J. T., Fan, C., Turman, Y. J., Shi, Y., Li, L., Topal, M. D., He, X., Chao, H. H., Prat, A., Silva, G. O., Iglesia, M. D., Zhao, W., Usary, J., Berg, J. S., Adams, M., Booker, J., Wu, J., Gulabani, A., Bodenheimer, T., Hoyle, A. P., Simons, J. V., Soloway, M. G., Mose, L. E., Jefferys, S. R., Balu, S., Parker, J. S., Hayes, D. N., Perou, C. M., Malik, S., Mahurkar, S., Shen, H., Weisenberger, D. J., Triche, T., Lai, P. H., Bootwalla, M. S., Maglinte, D. T., Berman, B. P., Van Den Berg, D. J., Baylin, S. B., Laird, P. W., Creighton, C. J., Donehower, L. A., Noble, M., Voet, D., Gehlenborg, N., Di Cara, D., Zhang, J., Zhang, H., Wu, C. J., Yingchun Liu, S., Lawrence, M. S., Zou, L., Sivachenko, A., Lin, P., Stojanov, P., Jing, R., Cho, J., Sinha, R., Park, R. W., Nazaire, M. D., Robinson, J., Thorvaldsdottir, H., Mesirov, J., Park, P. J., Reynolds, S., Kreisberg, R. B., Bernard, B., Bressler, R., Erkkila, T., Lin, J., Thorsson, V., Zhang, W., Shmulevich, I., Ciriello, G., Weinhold, N., Schultz, N., Gao, J., Cerami, E., Gross, B., Jacobsen, A., Sinha, R., Aksoy, B. A., Antipin, Y., Reva, B., Shen, R., Taylor, B. S., Ladanyi, M., Sander, C., Anur, P., Spellman, P. T., Lu, Y., Liu, W., Verhaak, R. R. G., Mills, G. B., Akbani, R., Zhang, N., Broom, B. M., Casasent, T. D., Wakefield, C., Unruh, A. K., Baggerly, K., Coombes, K., Weinstein, J. N., Haussler, D., Benz, C. C., Stuart, J. M., Benz, S. C., Zhu, J., Szeto, C. C., Scott, G. K., Yau, C., Paull, E. O., Carlin, D., Wong, C., Sokolov, A., Thusberg, J., Mooney, S., Ng, S., Goldstein, T. C., Ellrott, K., Grifford, M., Wilks, C., Ma, S., Craft, B., Yan, C., Hu, Y., Meerzaman, D., Gastier-Foster, J. M., Bowen, J., Ramirez, N. C., Black, A. D., Pyatt, R. E., White, P., Zmuda, E. J., Frick, J., Lichtenberg, T. M., Brookens, R., George, M. M., Gerken, M. A., Harper, H. A., Leraas, K. M., Wise, L. J., Tabler, T. R., McAllister, C., Barr, T., Hart-Kothari, M., Tarvin, K., Saller, C., Sandusky, G., Mitchell, C., Iacocca, M. V., Brown, J., Rabeno, B., Czerwinski, C., Petrelli, N., Dolzhansky, O., Abramov, M., Voronina, O., Potapova, O., Marks, J. R., Suchorska, W. M., Murawa, D., Kycler, W., Ibbs, M., Korski, K., Spychała, A., Murawa, P., Brzeziński, J. J., Perz, H., Łaźniak, R., Teresiak, M., Tatka, H., Leporowska, E., Bogusz-Czerniewicz, M., Malicki, J., Mackiewicz, A., Wiznerowicz, M., Van Le, X., Kohl, B., Viet Tien, N., Thorp, R., Van Bang, N., Sussman, H., Phu, B. D., Hajek, R., Hung, N. P., Phuong, T. V. T., Thang, H. Q., Khan, K. Z., Penny, R., Mallery, D., Curley, E., Shelton, C., Yena, P., Ingle, J. N., Couch, F. J., Lingle, W. L., King, T. A., Gonzalez-Angulo, A. M., Dyer, M. D., Liu, S., Meng, X., Patangan, M., Waldman, F., Stöppler, H., Rathmell, W. K., Thorne, L., Huang, M., Boice, L., Hill, A., Morrison, C., Gaudioso, C., Bshara, W., Daily, K., Egea, S. C., Pegram, M. D., Gomez-Fernandez, C., Dhir, R., Bhargava, R., Brufsky, A., Shriver, C. D., Hooke, J. A., Campbell, J. L., Mural, R. J., Hu, H., Somiari, S., Larson, C., Deyarmin, B., Kvecher, L., Kovatich, A. J., Ellis, M. J., Stricker, T., White, K., Olopade, O., Luo, C., Chen, Y., Bose, R., Chang, L. W., Beck, A. H., Pihl, T., Jensen, M., Sfeir, R., Kahn, A., Chu, A., Kothiyal, P., Wang, Z., Snyder, E., Pontius, J., Ayala, B., Backus, M., Walton, J., Baboud, J., Berton, D., Nicholls, M., Srinivasan, D., Raman, R., Girshik, S., Kigonya, P., Alonso, S., Sanbhadti, R., Barletta, S., Pot, D., Sheth, M., Demchok, J. A., Shaw, K. R. M., Yang, L., Eley, G., Ferguson, M. L., Tarnuzzer, R. W., Zhang, J., Dillon, L. A. L., Buetow, K., Fielding, P., Ozenberger, B. A., Guyer, M. S., Sofia, H. J. & Palchik, J. D., Oct 4 2012, In: Nature. 490, 7418, p. 61-70 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    9431 Scopus citations
  • Genomic landscape of non-small cell lung cancer in smokers and never-smokers

    Govindan, R., Ding, L., Griffith, M., Subramanian, J., Dees, N. D., Kanchi, K. L., Maher, C. A., Fulton, R., Fulton, L., Wallis, J., Chen, K., Walker, J., McDonald, S., Bose, R., Ornitz, D., Xiong, D., You, M., Dooling, D. J., Watson, M. & Mardis, E. R. & 1 others, Wilson, R. K., Sep 14 2012, In: Cell. 150, 6, p. 1121-1134 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1005 Scopus citations
  • Identification of targets of c-Src tyrosine kinase by chemical complementation and phosphoproteomics

    Ferrando, I. M., Chaerkady, R., Zhong, J., Molina, H., Jacob, H. K. C., Herbst-Robinson, K., Dancy, B. M., Katju, V., Bose, R., Zhang, J., Pandey, A. & Cole, P. A., Aug 2012, In: Molecular and Cellular Proteomics. 11, 8, p. 355-369 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    49 Scopus citations
  • Whole-genome analysis informs breast cancer response to aromatase inhibition

    Ellis, M. J., Ding, L., Shen, D., Luo, J., Suman, V. J., Wallis, J. W., Van Tine, B. A., Hoog, J., Goiffon, R. J., Goldstein, T. C., Ng, S., Lin, L., Crowder, R., Snider, J., Ballman, K., Weber, J., Chen, K., Koboldt, D. C., Kandoth, C. & Schierding, W. S. & 39 others, McMichael, J. F., Miller, C. A., Lu, C., Harris, C. C., McLellan, M. D., Wendl, M. C., Deschryver, K., Allred, D. C., Esserman, L., Unzeitig, G., Margenthaler, J., Babiera, G. V., Marcom, P. K., Guenther, J. M., Leitch, M., Hunt, K., Olson, J., Tao, Y., Maher, C. A., Fulton, L. L., Fulton, R. S., Harrison, M., Oberkfell, B., Du, F., Demeter, R., Vickery, T. L., Elhammali, A., Piwnica-Worms, H., McDonald, S., Watson, M., Dooling, D. J., Ota, D., Chang, L. W., Bose, R., Ley, T. J., Piwnica-Worms, D., Stuart, J. M., Wilson, R. K. & Mardis, E. R., Jun 21 2012, In: Nature. 486, 7403, p. 353-360 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    879 Scopus citations
  • 2011

    Carboxyl-group footprinting maps the dimerization interface and phosphorylation-induced conformational changes of a membrane-associated tyrosine kinase

    Zhang, H., Shen, W., Rempel, D., Monsey, J., Vidavsky, I., Gross, M. L. & Bose, R., Jun 2011, In: Molecular and Cellular Proteomics. 10, 6

    Research output: Contribution to journalArticlepeer-review

    Open Access
    28 Scopus citations
  • Exome sequencing and cis-regulatory mapping identify mutations in MAK, a gene encoding a regulator of ciliary length, as a cause of retinitis pigmentosa

    Özgül, R. K., Siemiatkowska, A. M., Yücel, D., Myers, C. A., Collin, R. W. J., Zonneveld, M. N., Beryozkin, A., Banin, E., Hoyng, C. B., Van Den Born, L. I., Bose, R., Shen, W., Sharon, D., Cremers, F. P. M., Klevering, B. J., Den Hollander, A. I. & Corbo, J. C., Aug 12 2011, In: American journal of human genetics. 89, 2, p. 253-264 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    94 Scopus citations
  • Target Proteins: Bottom-Up And Top-Down Proteomics

    Boyne, M. & Bose, R., Sep 23 2011, Protein and Peptide Mass Spectrometry in Drug Discovery. John Wiley and Sons, p. 89-100 12 p.

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

    2 Scopus citations
  • 2010

    Her4 and Her2/neu tyrosine kinase domains dimerize and activate in a reconstituted in vitro system

    Monsey, J., Shen, W., Schlesinger, P. & Bose, R., Mar 5 2010, In: Journal of Biological Chemistry. 285, 10, p. 7035-7044 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    53 Scopus citations
  • 2009

    The ErbB kinase domain: Structural perspectives into kinase activation and inhibition

    Bose, R. & Zhang, X., Feb 15 2009, In: Experimental Cell Research. 315, 4, p. 649-658 10 p.

    Research output: Contribution to journalReview articlepeer-review

    61 Scopus citations
  • 2008

    Human Proteinpedia enables sharing of human protein data [4]

    Mathivanan, S., Ahmed, M., Ahn, N. G., Alexandre, H., Amanchy, R., Andrews, P. C., Bader, J. S., Balgley, B. M., Bantscheff, M., Bennett, K. L., Björling, E., Blagoev, B., Bose, R., Brahmachari, S. K., Burlingame, A. S., Bustelo, X. R., Cagney, G., Cantin, G. T., Cardasis, H. L. & Celis, J. E. & 140 others, Chaerkady, R., Chu, F., Cole, P. A., Costello, C. E., Cotter, R. J., Crockett, D., DeLany, J. P., De Marzo, A. M., DeSouza, L. V., Deutsch, E. W., Dransfield, E., Drewes, G., Droit, A., Dunn, M. J., Elenitoba-Johnson, K., Ewing, R. M., Eyk, J. V., Faca, V., Falkner, J., Fang, X., Fenselau, C., Figeys, D., Gagné, P., Gelfi, C., Gevaert, K., Gimble, J. M., Gnad, F., Goel, R., Gromov, P., Hanash, S. M., Hancock, W. S., Harsha, H. C., Hart, G., Hays, F., He, F., Hebbar, P., Helsens, K., Hermeking, H., Hide, W., Hjernø, K., Hochstrasser, D. F., Hofmann, O., Horn, D. M., Hruban, R. H., Ibarrola, N., James, P., Jensen, O. N., Jensen, P. H., Jung, P., Kandasamy, K., Kheterpal, I., Kikuno, R. F., Korf, U., Körner, R., Kuster, B., Kwon, M. S., Lee, H. J., Lee, Y. J., Lefevre, M., Lehvaslaiho, M., Lescuyer, P., Levander, F., Lim, M. S., Löbke, C., Loo, J. A., Mann, M., Martens, L., Martinez-Heredia, J., McComb, M., McRedmond, J., Mehrle, A., Menon, R., Miller, C. A., Mischak, H., Mohan, S. S., Mohmood, R., Molina, H., Moran, M. F., Morgan, J. D., Moritz, R., Morzel, M., Muddiman, D. C., Nalli, A., Navarro, J. D., Neubert, T. A., Ohara, O., Oliva, R., Omenn, G. S., Oyama, M., Paik, Y. K., Pennington, K., Pepperkok, R., Periaswamy, B., Petricoin, E. F., Poirier, G. G., Prasad, T. S. K., Purvine, S. O., Rahiman, B. A., Ramachandran, P., Ramachandra, Y. L., Rice, R. H., Rick, J., Ronnholm, R. H., Salonen, J., Sanchez, J. C., Sayd, T., Seshi, B., Shankari, K., Sheng, S. J., Shetty, V., Shivakumar, K., Simpson, R. J., Sirdeshmukh, R., Michael Siu, K. W., Smith, J. C., Smith, R. D., States, D. J., Sugano, S., Sullivan, M., Superti-Furga, G., Takatalo, M., Thongboonkerd, V., Trinidad, J. C., Uhlen, M., Vandekerckhove, J., Vasilescu, J., Veenstra, T. D., Vidal-Taboada, J. M., Vihinen, M., Wait, R., Wang, X., Wiemann, S., Wu, B., Xu, T., Yates, J. R., Zhong, J., Zhou, M., Zhu, Y., Zurbig, P. & Pandey, A., Feb 2008, In: Nature Biotechnology. 26, 2, p. 164-167 4 p.

    Research output: Contribution to journalLetterpeer-review

    Open Access
    141 Scopus citations
  • Mechanism of Activation and Inhibition of the HER4/ErbB4 Kinase

    Qiu, C., Tarrant, M. K., Choi, S. H., Sathyamurthy, A., Bose, R., Banjade, S., Pal, A., Bornmann, W. G., Lemmon, M. A., Cole, P. A. & Leahy, D. J., Mar 11 2008, In: Structure. 16, 3, p. 460-467 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    155 Scopus citations
  • 2007

    Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface

    Zhang, X., Pickin, K. A., Bose, R., Jura, N., Cole, P. A. & Kuriyan, J., Nov 29 2007, In: Nature. 450, 7170, p. 741-744 4 p.

    Research output: Contribution to journalArticlepeer-review

    299 Scopus citations
  • 2006

    Phosphoproteomic analysis of Her2/neu signaling and inhibition

    Bose, R., Molina, H., Scott Patterson, A., Bitok, J. K., Periaswamy, B., Baderh, J. S., Pandey, A. & Cole, P. A., Jun 27 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 26, p. 9773-9778 6 p.

    Research output: Contribution to journalArticlepeer-review

    184 Scopus citations
  • Protein tyrosine kinase-substrate interactions

    Bose, R., Holbert, M. A., Pickin, K. A. & Cole, P. A., Dec 2006, In: Current Opinion in Structural Biology. 16, 6, p. 668-675 8 p.

    Research output: Contribution to journalReview articlepeer-review

    53 Scopus citations
  • 2000

    Measurement of ceramide levels by the diacylglycerol kinase reaction and by high-performance liquid chromatography-flourescence spectrometry

    Bose, R. & Kolesnick, R., 2000, In: Methods in enzymology. 322, p. 373-378 6 p.

    Research output: Contribution to journalReview articlepeer-review

    21 Scopus citations
  • Measurement of ceramide synthase activity

    Bose, R. & Kolesnick, R., 2000, In: Methods in enzymology. 322, p. 378-382 5 p.

    Research output: Contribution to journalReview articlepeer-review

    11 Scopus citations
  • 1998

    Autoantibodies to DEK oncoprotein in a patient with systemic lupus erythematosus and sarcoidosis

    Dong, X., Michelis, M. A., Wang, J., Bose, R., DeLange, T. & Reeves, W. H., Aug 1998, In: Arthritis and rheumatism. 41, 8, p. 1505-1510 6 p.

    Research output: Contribution to journalArticlepeer-review

    38 Scopus citations
  • Ceramide generation by the reaper protein is not blocked by the caspase inhibitor, p35

    Bose, R., Chen, P., Loconti, A., Grüllich, C., Abrams, J. M. & Kolesnick, R. N., Oct 30 1998, In: Journal of Biological Chemistry. 273, 44, p. 28852-28859 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    47 Scopus citations
  • 1996

    Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis

    Verheij, M., Bose, R., Lin, X. H., Yao, B., Jarvis, W. D., Grant, S., Birrer, M. J., Szabo, E., Zon, L. I., Kyriakis, J. M., Haimovitz-Friedman, A., Fuks, Z. & Kolesnick, R. N., Mar 7 1996, In: Nature. 380, 6569, p. 75-79 5 p.

    Research output: Contribution to journalArticlepeer-review

    1731 Scopus citations
  • 1995

    Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals

    Bose, R., Verheij, M., Haimovitz-Friedman, A., Scotto, K., Fuks, Z. & Kolesnick, R., Aug 11 1995, In: Cell. 82, 3, p. 405-414 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    804 Scopus citations
  • Overexpression of SIS2, which contains an extremely acidic region, increases the expression of SWI4, CLN1 and CLN2 in sit4 mutants

    Di Como, C. J., Bose, R. & Arndt, K. T., 1995, In: Genetics. 139, 1, p. 95-107 13 p.

    Research output: Contribution to journalArticlepeer-review

    70 Scopus citations
  • 1991

    The genes for a mouse hematopoietic differentiation marker called the heat‐stable antigen

    Wenger, R. H., Ayane, M., Bose, R., Köhler, G. & Nielsen, P. J., Apr 1991, In: European Journal of Immunology. 21, 4, p. 1039-1046 8 p.

    Research output: Contribution to journalArticlepeer-review

    65 Scopus citations