Research output per year
Research output per year
- 50 - 87 out of 87 results
Search results
-
2012
2′-O methylation of the viral mRNA cap by West Nile virus evades Ifit1-dependent and -independent mechanisms of host restriction in vivo
Szretter, K. J., Daniels, B. P., Cho, H., Gainey, M. D., Yokoyama, W. M., Gale, M., Virgin, H. W., Klein, R. S., Sen, G. C. & Diamond, M. S., May 2012, In: PLoS pathogens. 8, 5, e1002698.Research output: Contribution to journal › Article › peer-review
Open Access122 Scopus citations -
Astrocyte TNFR2 is required for CXCL12-mediated regulation of oligodendrocyte progenitor proliferation and differentiation within the adult CNS
Patel, J. R., Williams, J. L., Muccigrosso, M. M., Liu, L., Sun, T., Rubin, J. B. & Klein, R. S., Dec 2012, In: Acta Neuropathologica. 124, 6, p. 847-860 14 p.Research output: Contribution to journal › Article › peer-review
100 Scopus citations -
Rituximab combination therapy in relapsing multiple sclerosis
Cross, A. H., Klein, R. S. & Piccio, L., Nov 2012, In: Therapeutic Advances in Neurological Disorders. 5, 6, p. 311-319 9 p.Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
2011
Bone marrow transplantation augments the effect of brain- and spinal cord-directed adeno-associated virus 2/5 gene therapy by altering inflammation in the murine model of globoid-cell leukodystrophy
Reddy, A. S., Kim, J. H., Hawkins-Salsbury, J. A., Macauley, S. L., Tracy, E. T., Vogler, C. A., Han, X., Song, S. K., Wozniak, D. F., Fowler, S. C., Klein, R. S. & Sands, M. S., Jul 6 2011, In: Journal of Neuroscience. 31, 27, p. 9945-9957 13 p.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
CXCR7 antagonism prevents axonal injury during experimental autoimmune encephalomyelitis as revealed by in vivo axial diffusivity
Cruz-Orengo, L., Chen, Y. J., Kim, J. H., Dorsey, D., Song, S. K. & Klein, R. S., Dec 6 2011, In: Journal of Neuroinflammation. 8, 170.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity
Cruz-Orengo, L., Holman, D. W., Dorsey, D., Zhou, L., Zhang, P., Wright, M., McCandless, E. E., Patel, J. R., Luker, G. D., Littman, D. R., Russell, J. H. & Klein, R. S., Feb 14 2011, In: Journal of Experimental Medicine. 208, 2, p. 327-339 13 p.Research output: Contribution to journal › Article › peer-review
Open Access177 Scopus citations -
Quantification of increased cellularity during inflammatory demyelination
Wang, Y., Wang, Q., Haldar, J. P., Yeh, F. C., Xie, M., Sun, P., Tu, T. W., Trinkaus, K., Klein, R. S., Cross, A. H. & Song, S. K., Dec 2011, In: Brain. 134, 12, p. 3587-3598 12 p.Research output: Contribution to journal › Article › peer-review
Open Access267 Scopus citations -
2010
Changes in B- and T-lymphocyte and chemokine levels with rituximab treatment in multiple sclerosis
Piccio, L., Naismith, R. T., Trinkaus, K., Klein, R. S., Parks, B. J., Lyons, J. A. & Cross, A. H., Jun 2010, In: Archives of neurology. 67, 6, p. 707-714 8 p.Research output: Contribution to journal › Article › peer-review
Open Access191 Scopus citations -
CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination
Patel, J. R., McCandless, E. E., Dorsey, D. & Klein, R. S., Jun 15 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 24, p. 11062-11067 6 p.Research output: Contribution to journal › Article › peer-review
186 Scopus citations -
The innate immune adaptor molecule MyD88 restricts west nile virus replication and spread in neurons of the central nervous system
Szretter, K. J., Daffis, S., Patel, J., Suthar, M. S., Klein, R. S., Gale, M. & Diamond, M. S., Dec 2010, In: Journal of virology. 84, 23, p. 12125-12138 14 p.Research output: Contribution to journal › Article › peer-review
67 Scopus citations -
TNF-α-dependent regulation of CXCR3 expression modulates neuronal survival during West Nile virus encephalitis
Zhang, B., Patel, J., Croyle, M., Diamond, M. S. & Klein, R. S., Jul 2010, In: Journal of Neuroimmunology. 224, 1-2, p. 28-38 11 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
2009
IL-1R signaling within the central nervous system regulates CXCL12 expression at the blood-brain barrier and disease severity during experimental autoimmune encephalomyelitis
McCandless, E. E., Budde, M., Lees, J. R., Dorsey, D., Lyng, E. & Klein, R. S., Jul 1 2009, In: Journal of Immunology. 183, 1, p. 613-620 8 p.Research output: Contribution to journal › Article › peer-review
Open Access77 Scopus citations -
2008
CXCR3 mediates region-specific antiviral T cell trafficking within the central nervous system during west nile virus encephalitis
Zhang, B., Ying, K. C., Lu, B., Diamond, M. S. & Klein, R. S., Feb 15 2008, In: Journal of Immunology. 180, 4, p. 2641-2649 9 p.Research output: Contribution to journal › Article › peer-review
Open Access134 Scopus citations -
CXCR4 antagonism increases T cell trafficking in the central nervous system and improves survival from West Nile virus encephalitis
McCandless, E. E., Zhang, B., Diamond, M. S. & Klein, R. S., Aug 12 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 32, p. 11270-11275 6 p.Research output: Contribution to journal › Article › peer-review
44 Scopus citations -
Pathological expression of CXCL12 at the blood-brain barrier correlates with severity of multiple sclerosis
McCandless, E. E., Piccio, L., Woerner, B. M., Schmidt, R. E., Rubin, J. B., Cross, A. H. & Klein, R. S., Mar 2008, In: American Journal of Pathology. 172, 3, p. 799-808 10 p.Research output: Contribution to journal › Article › peer-review
Open Access104 Scopus citations -
Tumor necrosis factor alpha protects against lethal West Nile virus infection by promoting trafficking of mononuclear leukocytes into the central nervous system
Shrestha, B., Zhang, B., Purtha, W. E., Klein, R. S. & Diamond, M. S., Sep 2008, In: Journal of virology. 82, 18, p. 8956-8964 9 p.Research output: Contribution to journal › Article › peer-review
86 Scopus citations -
2007
CD40-CD40 ligand interactions promote trafficking of CD8+ T cells into the brain and protection against west Nile virus encephalitis
Sitati, E., McCandless, E. E., Klein, R. S. & Diamond, M. S., Sep 2007, In: Journal of virology. 81, 18, p. 9801-9811 11 p.Research output: Contribution to journal › Article › peer-review
49 Scopus citations -
Molecular targets for disrupting leukocyte trafficking during multiple sclerosis
McCandless, E. E. & Klein, R. S., Jul 2007, In: Expert reviews in molecular medicine. 9, 20, p. 1-19 19 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
2006
A tumor necrosis factor receptor 1-dependent conversation between central nervous system-specific T cells and the central nervous system is required for inflammatory infiltration of the spinal cord
Gimenez, M. A., Sim, J., Archambault, A. S., Klein, R. S. & Russell, J. H., Apr 2006, In: American Journal of Pathology. 168, 4, p. 1200-1209 10 p.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
CXCL12 limits inflammation by localizing mononuclear infiltrates to the perivascular space during experimental autoimmune encephalomyelitis
McCandless, E. E., Wang, Q., Mark Woerner, B., Harper, J. M. & Klein, R. S., Dec 1 2006, In: Journal of Immunology. 177, 11, p. 8053-8064 12 p.Research output: Contribution to journal › Article › peer-review
Open Access203 Scopus citations -
Detecting axon damage in spinal cord from a mouse model of multiple sclerosis
Kim, J. H., Budde, M. D., Liang, H. F., Klein, R. S., Russell, J. H., Cross, A. H. & Song, S. K., Mar 2006, In: Neurobiology of Disease. 21, 3, p. 626-632 7 p.Research output: Contribution to journal › Article › peer-review
207 Scopus citations -
Region-specific regulation of inflammation and pathogenesis in experimental autoimmune encephalomyelitis
Archambault, A. S., Sim, J., McCandless, E. E., Klein, R. S. & Russell, J. H., Dec 2006, In: Journal of Neuroimmunology. 181, 1-2, p. 122-132 11 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
2005
Neuronal CXCL10 directs CD8+ T-cell recruitment and control of West Nile virus encephalitis
Klein, R. S., Lin, E., Zhang, B., Luster, A. D., Tollett, J., Samuel, M. A., Engle, M. & Diamond, M. S., Sep 2005, In: Journal of virology. 79, 17, p. 11457-11466 10 p.Research output: Contribution to journal › Article › peer-review
346 Scopus citations -
2004
IFN-Inducible Protein 10/CXC Chemokine Ligand 10-Independent Induction of Experimental Autoimmune Encephalomyelitis
Klein, R. S., Izikson, L., Means, T., Gibson, H. D., Lin, E., Sobel, R. A., Weiner, H. L. & Luster, A. D., Jan 1 2004, In: Journal of Immunology. 172, 1, p. 550-559 10 p.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
2003
A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors
Rubin, J. B., Kung, A. L., Klein, R. S., Chan, J. A., Sun, Y. P., Schmidt, K., Kieran, M. W., Luster, A. D. & Segal, R. A., Nov 11 2003, In: Proceedings of the National Academy of Sciences of the United States of America. 100, 23, p. 13513-13518 6 p.Research output: Contribution to journal › Article › peer-review
Open Access502 Scopus citations -
2002
BDNF stimulates migration of cerebellar granule cells
Borghesani, P. R., Peyrin, J. M., Klein, R., Rubin, J., Carter, A. R., Schwartz, P. M., Luster, A., Corfas, G. & Sergal, R. A., 2002, In: Development. 129, 6, p. 1435-1442 8 p.Research output: Contribution to journal › Article › peer-review
131 Scopus citations -
Targeting monocyte recruitment in CNS autoimmune disease
Izikson, L., Klein, R. S., Luster, A. D. & Weiner, H. L., Jan 1 2002, In: Clinical Immunology. 103, 2, p. 125-131 7 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
2001
Ephrin-B reverse signaling is mediated by a novel PDZ-RGS protein and selectively inhibits G protein-coupled chemoattraction
Lu, Q., Sun, E. E., Klein, R. S. & Flanagan, J. G., Apr 6 2001, In: Cell. 105, 1, p. 69-79 11 p.Research output: Contribution to journal › Article › peer-review
Open Access119 Scopus citations -
SDF-1α induces chemotaxis and enhances Sonic hedgehog-induced proliferation of cerebellar granule cells
Klein, R. S., Rubin, J. B., Gibson, H., DeHaan, E. N., Alvarez-Hernandez, Segal, R. A. & Luster, A. D., 2001, In: Development. 128, 11, p. 1971-1981 11 p.Research output: Contribution to journal › Article › peer-review
265 Scopus citations -
2000
Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2
Izikson, L., Klein, R. S., Charo, I. F., Weiner, H. L. & Luster, A. D., Oct 2 2000, In: Journal of Experimental Medicine. 192, 7, p. 1075-1080 6 p.Research output: Contribution to journal › Article › peer-review
Open Access522 Scopus citations -
1999
Chemokine receptor expression and signaling in macaque and human fetal neurons and astrocytes: Implications for the neuropathogenesis of AIDS
Klein, R. S., Williams, K. C., Alvarez-Hernandez, X., Westmoreland, S., Force, T., Lackner, A. A. & Luster, A. D., Aug 1 1999, In: Journal of Immunology. 163, 3, p. 1636-1646 11 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
1993
Differential Effects of a Phorbol Ester on Carboxypeptidase E in Cultured Astrocytes and AtT‐20 Cells, a Neuroendocrine Cell Line
Klein, R. S. & Flicker, L. D., May 1993, In: Journal of Neurochemistry. 60, 5, p. 1615-1625 11 p.Research output: Contribution to journal › Article › peer-review
-
1992
Cultured astrocytes express mRNA for peptidylglycine-α-amidating monooxygenase, a neuropeptide processing enzyme
Klein, R. S. & Fricker, L. D., Nov 20 1992, In: Brain Research. 596, 1-2, p. 202-208 7 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Heterogeneous expression of carboxypeptidase E and proenkephalin mRNAs by cultured astrocytes
Klein, R. S. & Fricker, L. D., Jan 13 1992, In: Brain Research. 569, 2, p. 300-310 11 p.Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
Secretion of Carboxypeptidase E from Cultured Astrocytes and from AtT‐20 Cells, a Neuroendocrine Cell Line: Implications for Neuropeptide Biosynthesis
Klein, R. S., Das, B. & Fricker, L. D., Jun 1992, In: Journal of Neurochemistry. 58, 6, p. 2011-2018 8 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
1991
Regulation of carboxypeptidase E (enkephalin convertase)
Fricker, L. D., Das, B., Klein, R. S., Greene, D. & Jung, Y. K., 1991, In: NIDA Research Monograph Series. 111, p. 171-187 17 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
1986
Molecular and Immunocytochemical Studies of Neurofibromas and Related Cell Types
PINTAR, JOHN. E., SONNENFELD, KENNETH. H., FISHER, JOHN., KLEIN, ROBYN. S. & KREIDER, BARBARA., Dec 1986, In: Annals of the New York Academy of Sciences. 486, 1, p. 96-106 11 p.Research output: Contribution to journal › Article › peer-review