Robert Schreiber

2008

Interferon-α initiates type 1 diabetes in nonobese diabetic mice

Li, Q., Xu, B., Michie, S. A., Rubins, K. H., Schreriber, R. D. & McDevitt, H. O., Aug 26 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 34, p. 12439-12444 6 p.

Research output: Contribution to journal › Article › peer-review

147 Scopus citations

Prolongation of cardiac and islet allograft survival by a blocking hamster anti-mouse CXCR3 monoclonal antibody

Uppaluri, R., Sheehan, K. C. F., Wang, L., Bui, J. D., Brotman, J. J., Lu, B., Gerard, C., Hancock, W. W. & Schreiber, R. D., Jul 15 2008, In: Transplantation. 86, 1, p. 137-147 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

64 Scopus citations

2007

ABIN-3: A molecular basis for species divergence in interleukin-10-induced anti-inflammatory actions

Weaver, B. K., Bohn, E., Judd, B. A., Gil, M. P. & Schreiber, R. D., Jul 2007, In: Molecular and cellular biology. 27, 13, p. 4603-4616 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

45 Scopus citations

Adaptive immunity maintains occult cancer in an equilibrium state

Koebel, C. M., Vermi, W., Swann, J. B., Zerafa, N., Rodig, S. J., Old, L. J., Smyth, M. J. & Schreiber, R. D., Dec 6 2007, In: Nature. 450, 7171, p. 903-907 5 p.

Research output: Contribution to journal › Article › peer-review

1123 Scopus citations

A novel c-Jun-dependent signal transduction pathway necessary for the transcriptional activation of interferon γ response genes

Gough, D. J., Sabapathy, K., Ko, E. Y. N., Arthur, H. A., Schreiber, R. D., Trapani, J. A., Clarke, C. J. P. & Johnstone, R. W., Jan 12 2007, In: Journal of Biological Chemistry. 282, 2, p. 938-946 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

56 Scopus citations

Cancer immunosurveillance, immunoediting and inflammation: independent or interdependent processes?

Bui, J. D. & Schreiber, R. D., Apr 2007, In: Current Opinion in Immunology. 19, 2, p. 203-208 6 p.

Research output: Contribution to journal › Review article › peer-review

264 Scopus citations

Type I IFN contributes to NK cell homeostasis, activation, and antitumor function

Swann, J. B., Hayakawa, Y., Zerafa, N., Sheehan, K. C. F., Scott, B., Schreiber, R. D., Hertzog, P. & Smyth, M. J., Jun 15 2007, In: Journal of Immunology. 178, 12, p. 7540-7549 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

263 Scopus citations

Vav proteins control MyD88-dependent oxidative burst

Miletic, A. V., Graham, D. B., Montgrain, V., Fujikawa, K., Kloeppel, T., Brim, K., Weaver, B., Schreiber, R., Xavier, R. & Swat, W., Apr 15 2007, In: Blood. 109, 8, p. 3360-3368 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

71 Scopus citations

2006

Blocking monoclonal antibodies specific for mouse IFN-α/β receptor subunit 1 (IFNAR-1) from mice immunized by in vivo hydrodynamic transfection

Sheehan, K. C. F., Lai, K. S., Dunn, G. P., Bruce, A. T., Diamond, M. S., Heutel, J. D., Dungo-Arthur, C., Carrero, J. A., White, J. M., Hertzog, P. J. & Schreiber, R. D., Nov 2006, In: Journal of Interferon and Cytokine Research. 26, 11, p. 804-819 16 p.

Research output: Contribution to journal › Article › peer-review

221 Scopus citations

Bone marrow stromal cell antigen 2 is a specific marker of type I IFN-producing cells in the naive mouse, but a promiscuous cell surface antigen following IFN stimulation

Blasius, A. L., Giurisato, E., Cella, M., Schreiber, R. D., Shaw, A. S. & Colonna, M., Sep 1 2006, In: Journal of Immunology. 177, 5, p. 3260-3265 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

367 Scopus citations

Cancer Immunosurveillance and Immunoediting: The Roles of Immunity in Suppressing Tumor Development and Shaping Tumor Immunogenicity

Smyth, M. J., Dunn, G. P. & Schreiber, R. D., 2006, In: Advances in Immunology. 90, p. 1-50 50 p.

Research output: Contribution to journal › Review article › peer-review

707 Scopus citations

Comparative analysis of regulatory and effector T cells in progressively growing versus rejecting tumors of similar origins

Bui, J. D., Uppaluri, R., Hsieh, C. S. & Schreiber, R. D., Jul 15 2006, In: Cancer research. 66, 14, p. 7301-7309 9 p.

Research output: Contribution to journal › Article › peer-review

87 Scopus citations

IFN-dependent down-regulation of the NKG2D ligand H60 on tumors

Bui, J. D., Carayannopoulos, L. N., Lanier, L. L., Yokoyama, W. M. & Schreiber, R. D., Jan 15 2006, In: Journal of Immunology. 176, 2, p. 905-913 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

93 Scopus citations

Interferons, immunity and cancer immunoediting

Dunn, G. P., Koebel, C. M. & Schreiber, R. D., Nov 13 2006, In: Nature Reviews Immunology. 6, 11, p. 836-848 13 p.

Research output: Contribution to journal › Review article › peer-review

1322 Scopus citations

NF-κB-inducing kinase regulates selected gene expression in the Nod2 signaling pathway

Pan, Q., Kravchenko, V., Katz, A., Huang, S., Ii, M., Mathison, J. C., Kobayashi, K., Flavell, R. A., Schreiber, R. D., Goeddel, D. & Ulevitch, R. J., Apr 2006, In: Infection and immunity. 74, 4, p. 2121-2127 7 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

47 Scopus citations

Novel STAT1 alleles in otherwise healthy patients with mycobacterial disease

Chapgier, A., Boisson-Dupuis, S., Jouanguy, E., Vogt, G., Feinberg, J., Prochnicka-Chalufour, A., Casrouge, A., Yang, K., Soudais, C., Fieschi, C., Santos, O. F., Bustamante, J., Picard, C., De Beaucoudrey, L., Emile, J. F., Arkwright, P. D., Schreiber, R. D., Rolinck-Werninghaus, C., Rösen-Wolff, A. & Magdorf, K. & 2 others, Roesler, J. & Casanova, J. L., 2006, In: PLoS genetics. 2, 8, p. 1193-1206 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

154 Scopus citations

Perforin and Granzymes Have Distinct Roles in Defensive Immunity and Immunopathology

van Dommelen, S. L. H., Sumaria, N., Schreiber, R. D., Scalzo, A. A., Smyth, M. J. & Degli-Esposti, M. A., Nov 2006, In: Immunity. 25, 5, p. 835-848 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

131 Scopus citations

Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity

Fenner, J. E., Starr, R., Cornish, A. L., Zhang, J. G., Metcalf, D., Schreiber, R. D., Sheehan, K., Hilton, D. J., Alexander, W. S. & Hertzog, P. J., Jan 2006, In: Nature immunology. 7, 1, p. 33-39 7 p.

Research output: Contribution to journal › Article › peer-review

240 Scopus citations

2005

A critical function for type I interferons in cancer immunoediting

Dunn, G. P., Bruce, A. T., Sheehan, K. C. F., Shankaran, V., Uppaluri, R., Bui, J. D., Diamond, M. S., Koebel, C. M., Arthur, C., White, J. M. & Schreiber, R. D., 2005, In: Nature immunology. 6, 7, p. 722-729 8 p.

Research output: Contribution to journal › Article › peer-review

520 Scopus citations

Breaking down the barriers to cancer immunotherapy

Puré, E., Allison, J. P. & Schreiber, R. D., Dec 2005, In: Nature immunology. 6, 12, p. 1207-1210 4 p.

Research output: Contribution to journal › Article › peer-review

56 Scopus citations

Cancer Vaccines 2004 opening address: The molecular and cellular basis of cancer immunosurveillance and immunoediting

Schreiber, R. D., Apr 6 2005, In: Cancer Immunity. 5, SUPPL. 1

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Definition of target antigens for naturally occurring CD4⁺ CD25⁺ regulatory T cells

Nishikawa, H., Kato, T., Tawara, I., Saito, K., Ikeda, H., Kuribayashi, K., Allen, P. M., Schreiber, R. D., Sakaguchi, S., Old, L. J. & Shiku, H., Mar 7 2005, In: Journal of Experimental Medicine. 201, 5, p. 681-686 6 p.

Research output: Contribution to journal › Article › peer-review

118 Scopus citations

Erratum: A critical function for type I interferons in cancer immunoediting (Nature Immunology (2005) vol. 6 (722-729))

Cunn, G. P., Bruce, A. T., Sheehan, K. C. F., Shankaran, V., Uppaluri, R., Bui, J. D., Diamond, M. S., Koebel, C. M., Arthur, C., White, J. M. & Schreiber, R. D., Aug 1 2005, In: Nature immunology. 6, 8, 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

Gains of glycosylation comprise an unexpectedly large group of pathogenic mutations

Vogt, G., Chapgier, A., Yang, K., Chuzhanova, N., Feinberg, J., Fieschi, C., Boisson-Dupuis, S., Alcais, A., Filipe-Santos, O., Bustamante, J., De Beaucoudrey, L., Al-Mohsen, I., Al-Hajjar, S., Al-Ghonaium, A., Adimi, P., Mirsaeidi, M., Khalilzadeh, S., Rosenzweig, S., De La Galle Martin, O. & Bauer, T. R. & 12 others, Puck, J. M., Ochs, H. D., Furthner, D., Engelhorn, C., Belohradsky, B., Mansouri, D., Holland, S. M., Schreiber, R. D., Abel, L., Cooper, D. N., Soudais, C. & Casanova, J. L., 2005, In: Nature Genetics. 37, 7, p. 692-700 9 p.

Research output: Contribution to journal › Article › peer-review

195 Scopus citations

IFN unresponsiveness in LNCaP cells due to the lack of JAK1 gene expression

Dunn, G. P., Sheehan, K. C. F., Old, L. J. & Schreiber, R. D., Apr 15 2005, In: Cancer research. 65, 8, p. 3447-3453 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

144 Scopus citations

IFN-γ controls the generation/activation of CD4⁺CD25 ⁺ regulatory T cells in antitumor immune response

Nishikawa, H., Kato, T., Tawara, I., Ikeda, H., Kuribayashi, K., Allen, P. M., Schreiber, R. D., Old, L. J. & Shiku, H., Oct 1 2005, In: Journal of Immunology. 175, 7, p. 4433-4440 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

87 Scopus citations

Interferon-γ and cancer immunoediting

Dunn, G. P., Ikeda, H., Bruce, A. T., Koebel, C., Uppaluri, R., Bui, J., Chan, R., Diamond, M., White, J. M., Sheehan, K. C. F. & Schreiber, R. D., 2005, In: Immunologic Research. 32, 1-3, p. 231-245 15 p.

Research output: Contribution to journal › Review article › peer-review

126 Scopus citations

The continuing evolution of immunology at Washington University

Allen, P. M. & Schreiber, R. D., Jan 1 2005, In: Immunologic Research. 32, 1-3, p. 1-3 3 p.

Research output: Contribution to journal › Editorial

2004

A cancer immunosurveillance controversy (multiple letters)

Qin, Z., Blankenstein, T., Schreiber, R. D., Old, L. J., Hayday, A. C. & Smyth, M. J., Jan 1 2004, In: Nature immunology. 5, 1, p. 3-5 3 p.

Research output: Contribution to journal › Letter › peer-review

48 Scopus citations

A role for the immunological synapse in lineage commitment of CD4 lymphocytes

Maldonade, R. A., Irvine, D. J., Schreiber, R. & Glimcher, L. H., Sep 30 2004, In: Nature. 431, 7008, p. 527-532 6 p.

Research output: Contribution to journal › Review article › peer-review

162 Scopus citations

Enhanced tumorigenesis in HTLV-1 Tax-transgenic mice deficient in interferon-gamma

Mitra-Kaushik, S., Harding, J., Hess, J., Schreiber, R. & Ratner, L., Nov 15 2004, In: Blood. 104, 10, p. 3305-3311 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

47 Scopus citations

The immunobiology of cancer immunosurveillance and immunoediting

Dunn, G. P., Old, L. J. & Schreiber, R. D., Aug 2004, In: Immunity. 21, 2, p. 137-148 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

2395 Scopus citations

The three Es of cancer immunoediting

Dunn, G. P., Old, L. J. & Schreiber, R. D., 2004, In: Annual Review of Immunology. 22, p. 329-360 32 p.

Research output: Contribution to journal › Review article › peer-review

2391 Scopus citations

2003

Impaired response to interferon-α/β and lethal viral disease in human STAT1 deficiency

Dupuis, S., Jouanguy, E., Al-Hajjar, S., Fieschi, C., Zaid Al-Mohsen, I., Al-Jumaah, S., Yang, K., Chapgier, A., Eidenschenk, C., Eid, P., Al Ghonaium, A., Tufenkeji, H., Frayha, H., Al-Gazlan, S., Al-Rayes, H., Schreiber, R. D., Gresser, I. & Casanova, J. L., Mar 1 2003, In: Nature Genetics. 33, 3, p. 388-391 4 p.

Research output: Contribution to journal › Article › peer-review

691 Scopus citations

Interferon-γ

Schreiber, G. H. & Schreiber, R. D., Jul 7 2003, The Cytokine Handbook. Elsevier Inc., p. 567-601 35 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

28 Scopus citations

The IκB function of NF-κB2 p100 controls stimulated osteoclastogenesis

Novack, D. V., Yin, L., Hagen-Stapleton, A., Schreiber, R. D., Goeddel, D. V., Ross, F. P. & Teitelbaum, S. L., Sep 1 2003, In: Journal of Experimental Medicine. 198, 5, p. 771-781 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

248 Scopus citations

Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice

Kobayashi, M., Kweon, M. N., Kuwata, H., Schreiber, R. D., Kiyono, H., Takeda, K. & Akira, S., May 2003, In: Journal of Clinical Investigation. 111, 9, p. 1297-1308 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

232 Scopus citations

2002

Cancer immunoediting: From immunosurveillance to tumor escape

Dunn, G. P., Bruce, A. T., Ikeda, H., Old, L. J. & Schreiber, R. D., Nov 2002, In: Nature immunology. 3, 11, p. 991-998 8 p.

Research output: Contribution to journal › Review article › peer-review

4188 Scopus citations

Cutting edge: IFN-producing cells respond to CXCR3 ligands in the presence of CXCL12 and secrete inflammatory chemokines upon activation

Krug, A., Uppaluri, R., Facchetti, F., Dorner, B. G., Sheehan, K. C. F., Schreiber, R. D., Cella, M. & Colonna, M., Dec 1 2002, In: Journal of Immunology. 169, 11, p. 6079-6083 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

131 Scopus citations

Cytokine signaling in 2002: New surprises in the Jak/Stat pathway

OShea, J. J., Gadina, M. & Schreiber, R. D., 2002, In: Cell. 109, 2 SUPPL. 1, p. S121-S131

Research output: Contribution to journal › Review article › peer-review

Open Access

1001 Scopus citations

STAT1 deficiency unexpectedly and markedly exacerbates the pathophysiological actions of IFN-α in the central nervous system

Wang, J., Schreiber, R. D. & Campbell, I. L., Dec 10 2002, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 25, p. 16209-16214 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

56 Scopus citations

Stat1-dependent and -independent pathways in IFN-γ-dependent signaling

Ramana, C. V., Gil, M. P., Schreiber, R. D. & Stark, G. R., Feb 1 2002, In: Trends in Immunology. 23, 2, p. 96-101 6 p.

Research output: Contribution to journal › Review article › peer-review

496 Scopus citations

The roles of IFNγ in protection against tumor development and cancer immunoediting

Ikeda, H., Old, L. J. & Schreiber, R. D., 2002, In: Cytokine and Growth Factor Reviews. 13, 2, p. 95-109 15 p.

Research output: Contribution to journal › Review article › peer-review

763 Scopus citations

2001

A completely foreign receptor can mediate an interferon-γ-like response

Strobl, B., Arulampalam, V., Is'Harc, H., Newman, S. J., Schlaak, J. F., Watling, D., Costa-Pereira, A. P., Schaper, F., Behrmann, I., Sheehan, K. C. F., Schreiber, R. D., Horn, F., Heinrich, P. C. & Kerr, I. M., Oct 1 2001, In: EMBO Journal. 20, 19, p. 5431-5442 12 p.

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Biologic consequences of Stat1-independent IFN signaling

Gil, M. P., Bohn, E., O'Guin, A. K., Ramana, C. V., Levine, B., Stark, G. R., Virgin, H. W. & Schreiber, R. D., Jun 5 2001, In: Proceedings of the National Academy of Sciences of the United States of America. 98, 12, p. 6680-6685 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

305 Scopus citations

Defective lymphotoxin-β receptor-induced NF-κB transcriptional activity in NIK-deficient mice

Yin, L., Wu, L., Wesche, H., Arthur, C. D., White, J. M., Goeddel, D. V. & Schreiber, R. D., Mar 16 2001, In: Science. 291, 5511, p. 2162-2165 4 p.

Research output: Contribution to journal › Article › peer-review

359 Scopus citations

ERK1 and ERK2 activate CCAAAT/enhancer-binding protein-β-dependent gene transcription in response to interferon-γ

Hu, J., Roy, S. K., Shapiro, P. S., Rodig, S. R., Reddy, S. P. M., Platanias, L. C., Schreiber, R. D. & Kalvakolanu, D. V., Jan 5 2001, In: Journal of Biological Chemistry. 276, 1, p. 287-297 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

139 Scopus citations

IFNγ, and lymphocytes prevent primary tumour development and shape tumour immunogenicity

Shankaran, V., Ikeda, H., Bruce, A. T., White, J. M., Swanson, P. E., Old, L. J. & Schreiber, R. D., Apr 26 2001, In: Nature. 410, 6832, p. 1107-1111 5 p.

Research output: Contribution to journal › Article › peer-review

2297 Scopus citations

Impairment of mycobacterial but not viral immunity by a germline human STAT1 mutation

Dupuis, S., Dargemont, C., Fieschi, C., Thomassin, N., Rosenzweig, S., Harris, J., Holland, S. M., Schreiber, R. D. & Casanova, J. L., Jul 13 2001, In: Science. 293, 5528, p. 300-303 4 p.

Research output: Contribution to journal › Article › peer-review

451 Scopus citations

Measurement of mouse and human interferon gamma

Schreiber, R. D., May 1 2001, In: Current protocols in immunology / edited by John E. Coligan ... [et al.]. Chapter 6, p. Unit 6.8

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Robert Schreiber

Research output

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