Robert Gropler

Professor of Radiology, Senior Vice Chair - Division of Radiological Sciences, Research Laboratories, Associate Professor of Biomedical Engineering, Associate Professor of Medicine

    • 8770
    1990 …2024

    Research activity per year

    If you made any changes in Pure these will be visible here soon.

    Personal profile

    Research interests

    The focus of our investigative efforts is on the role of myocardial metabolic remodeling in both normal and abnormal cardiac states. Quantification of myocardial perfusion and substrate metabolism is performed with positron emission tomography using novel PET radiopharmaceuticals and well-validated kinetic models. The measurements of myocardial perfusion and metabolism are then correlated to measurements of left ventricular systolic and diastolic function obtained with either echocardiography or MRI. These measurements are obtained in variety models of disease ranging from rodents to humans. Active areas of investigation include the role nitric oxide and peroxisome proliferator-activated receptor on the age related decline in myocardial fatty acid metabolism, the effect of fatty acid delivery on myocardial substrate metabolism in type 2 diabetes mellitus, and the relationship between myocardial and whole-body substrate metabolism in obesity.

    Clinical interests

    Nuclear medicine, cardiovascular imaging, coronary artery disease, PET imaging


    Dive into the research topics where Robert Gropler is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
    • 1 Similar Profiles

    Collaborations and top research areas from the last five years

    Recent external collaboration on country/territory level. Dive into details by clicking on the dots or