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Robert Fulton

Assistant Professor of Genetics

    • 168377
      Citations
    1994 …2022

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    • 2016

      The genomic landscape of core-binding factor acute myeloid leukemias

      Faber, Z. J., Chen, X., Gedman, A. L., Boggs, K., Cheng, J., Ma, J., Radtke, I., Chao, J. R., Walsh, M. P., Song, G., Andersson, A. K., Dang, J., Dong, L., Liu, Y., Huether, R., Cai, Z., Mulder, H., Wu, G., Edmonson, M., Rusch, M., & 29 othersQu, C., Li, Y., Vadodaria, B., Wang, J., Hedlund, E., Cao, X., Yergeau, D., Nakitandwe, J., Pounds, S. B., Shurtleff, S., Fulton, R. S., Fulton, L. L., Easton, J., Parganas, E., Pui, C. H., Rubnitz, J. E., Ding, L., Mardis, E. R., Wilson, R. K., Gruber, T. A., Mullighan, C. G., Schlenk, R. F., Paschka, P., Döhner, K., Döhner, H., Bullinger, L., Zhang, J., Klco, J. M. & Downing, J. R., Dec 1 2016, In: Nature Genetics. 48, 12, p. 1551-1556 6 p.

      Research output: Contribution to journal › Article › peer-review

      164 Scopus citations

    • TP53 and decitabine in acute myeloid leukemia and myelodysplastic syndromes

      Welch, J. S., Petti, A. A., Miller, C. A., Fronick, C. C., O'Laughlin, M., Fulton, R. S., Wilson, R. K., Baty, J. D., Duncavage, E. J., Tandon, B., Lee, Y. S., Wartman, L. D., Uy, G. L., Ghobadi, A., Tomasson, M. H., Pusic, I., Romee, R., Fehniger, T. A., Stockerl-Goldstein, K. E., Vij, R., & 19 othersOh, S. T., Abboud, C. N., Cashen, A. F., Schroeder, M. A., Jacoby, M. A., Heath, S. E., Luber, K., Janke, M. R., Hantel, A., Khan, N., Sukhanova, M. J., Knoebel, R. W., Stock, W., Graubert, T. A., Walter, M. J., Westervelt, P., Link, D. C., Dipersio, J. F. & Ley, T. J., Nov 24 2016, In: New England Journal of Medicine. 375, 21, p. 2023-2036 14 p.

      Research output: Contribution to journal › Article › peer-review

      548 Scopus citations

    • Truncating Prolactin Receptor Mutations Promote Tumor Growth in Murine Estrogen Receptor-Alpha Mammary Carcinomas

      Griffith, O. L., Chan, S. R., Griffith, M., Krysiak, K., Skidmore, Z. L., Hundal, J., Allen, J. A., Arthur, C. D., Runci, D., Bugatti, M., Miceli, A. P., Schmidt, H., Trani, L., Kanchi, K. L., Miller, C. A., Larson, D. E., Fulton, R. S., Vermi, W., Wilson, R. K., Schreiber, R. D., & 1 othersMardis, E. R., Sep 27 2016, In: Cell Reports. 17, 1, p. 249-260 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      16 Scopus citations

    • Tumor Evolution in Two Patients with Basal-like Breast Cancer: A Retrospective Genomics Study of Multiple Metastases

      Hoadley, K. A., Siegel, M. B., Kanchi, K. L., Miller, C. A., Ding, L., Zhao, W., He, X., Parker, J. S., Wendl, M. C., Fulton, R. S., Demeter, R. T., Wilson, R. K., Carey, L. A., Perou, C. M. & Mardis, E. R., Dec 2016, In: PLoS medicine. 13, 12, e1002174.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      71 Scopus citations
    • 2015

      Association between mutation clearance after induction therapy and outcomes in acute myeloid leukemia

      Klco, J. M., Miller, C. A., Griffith, M., Petti, A., Spencer, D. H., Ketkar-Kulkarni, S., Wartman, L. D., Christopher, M., Lamprecht, T. L., Helton, N. M., Duncavage, E. J., Payton, J. E., Baty, J., Heath, S. E., Griffith, O. L., Shen, D., Hundal, J., Chang, G. S., Fulton, R., O'Laughlin, M., & 16 othersFronick, C., Magrini, V., Demeter, R. T., Larson, D. E., Kulkarni, S., Ozenberger, B. A., Welch, J. S., Walter, M. J., Graubert, T. A., Westervelt, P., Radich, J. P., Link, D. C., Mardis, E. R., DiPersio, J. F., Wilson, R. K. & Ley, T. J., Aug 25 2015, In: JAMA - Journal of the American Medical Association. 314, 8, p. 811-822 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      255 Scopus citations

    • Clonal evolution revealed by whole genome sequencing in a case of primary myelofibrosis transformed to secondary acute myeloid leukemia

      Engle, E. K., Fisher, D. A. C., Miller, C. A., McLellan, M. D., Fulton, R. S., Moore, D. M., Wilson, R. K., Ley, T. J. & Oh, S. T., Apr 15 2015, In: Leukemia. 29, 4, p. 869-876 8 p.

      Research output: Contribution to journal › Article › peer-review

      40 Scopus citations

    • Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells

      Spencer, D. H., Young, M. A., Lamprecht, T. L., Helton, N. M., Fulton, R., O'Laughlin, M., Fronick, C., Magrini, V., Demeter, R. T., Miller, C. A., Klco, J. M., Wilson, R. K. & Ley, T. J., Jun 9 2015, In: Leukemia. 29, 6, p. 1279-1289 11 p.

      Research output: Contribution to journal › Article › peer-review

      74 Scopus citations

    • FHBG PET/CT imaging of CD34-TK75 transduced donor T cells in relapsed allogeneic stem cell transplant patients: Safety and feasibility

      Eissenberg, L. G., Rettig, M. P., Ritchey, J. K., Prior, J. L., Schwarz, S. W., Frye, J., White, B. S., Fulton, R. S., Ghobadi, A., Cooper, M. L., Couriel, D. R., Seegulam, M. E., Piwnica-Worms, D., Dehdashti, F., Cornetta, K. & DiPersio, J. F., Jun 1 2015, In: Molecular Therapy. 23, 6, p. 1110-1122 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      18 Scopus citations

    • Genetic heterogeneity of induced pluripotent stem cells: Results from 24 clones derived from a single C57BL/6 mouse

      Li, C., Klco, J. M., Helton, N. M., George, D. R., Mudd, J. L., Miller, C. A., Lu, C., Fulton, R., O'Laughlin, M., Fronick, C., Wilson, R. K. & Ley, T. J., Mar 23 2015, In: PloS one. 10, 3, e0120585.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      10 Scopus citations

    • Genomic analysis of germ line and somatic variants in familial myelodysplasia/acute myeloid leukemia

      Churpek, J. E., Pyrtel, K., Kanchi, K. L., Shao, J., Koboldt, D., Miller, C. A., Shen, D., Fulton, R., O'Laughlin, M., Fronick, C., Pusic, I., Uy, G. L., Braunstein, E. M., Levis, M., Ross, J., Elliott, K., Heath, S., Jiang, A., Westervelt, P., DiPersio, J. F., & 7 othersLink, D. C., Walter, M. J., Welch, J., Wilson, R., Ley, T. J., Godley, L. A. & Graubert, T. A., Nov 26 2015, In: Blood. 126, 22, p. 2484-2490 7 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      156 Scopus citations

    • Germline genetic variation in ETV6 and risk of childhood acute lymphoblastic leukaemia: A systematic genetic study

      Moriyama, T., Metzger, M. L., Wu, G., Nishii, R., Qian, M., Devidas, M., Yang, W., Cheng, C., Cao, X., Quinn, E., Raimondi, S., Gastier-Foster, J. M., Raetz, E., Larsen, E., Martin, P. L., Bowman, W. P., Winick, N., Komada, Y., Wang, S., Edmonson, M., & 12 othersXu, H., Mardis, E., Fulton, R., Pui, C. H., Mullighan, C., Evans, W. E., Zhang, J., Hunger, S. P., Relling, M. V., Nichols, K. E., Loh, M. L. & Yang, J. J., 2015, In: The Lancet Oncology. 16, 16, p. 1659-1666 8 p.

      Research output: Contribution to journal › Article › peer-review

      126 Scopus citations

    • Identification of functional variants for cleft lip with or without cleft palate in or near PAX7, FGFR2, and NOG by targeted sequencing of GWAS loci

      Leslie, E. J., Taub, M. A., Liu, H., Steinberg, K. M., Koboldt, D. C., Zhang, Q., Carlson, J. C., Hetmanski, J. B., Wang, H., Larson, D. E., Fulton, R. S., Kousa, Y. A., Fakhouri, W. D., Naji, A., Ruczinski, I., Begum, F., Parker, M. M., Busch, T., Standley, J., Rigdon, J., & 14 othersHecht, J. T., Scott, A. F., Wehby, G. L., Christensen, K., Czeizel, A. E., Deleyiannis, F. W. B., Schutte, B. C., Wilson, R. K., Cornell, R. A., Lidral, A. C., Weinstock, G. M., Beaty, T. H., Marazita, M. L. & Murray, J. C., Mar 5 2015, In: American journal of human genetics. 96, 3, p. 397-411 15 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      105 Scopus citations

    • Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children

      Xu, H., Zhang, H., Yang, W., Yadav, R., Morrison, A. C., Qian, M., Devidas, M., Liu, Y., Perez-Andreu, V., Zhao, X., Gastier-Foster, J. M., Lupo, P. J., Neale, G., Raetz, E., Larsen, E., Bowman, W. P., Carroll, W. L., Winick, N., Williams, R., Hansen, T., & 13 othersHolm, J. C., Mardis, E., Fulton, R., Pui, C. H., Zhang, J., Mullighan, C. G., Evans, W. E., Hunger, S. P., Gupta, R., Schmiegelow, K., Loh, M. L., Relling, M. V. & Yang, J. J., Jun 24 2015, In: Nature communications. 6, 7553.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      55 Scopus citations

    • Mutant U2AF1 Expression Alters Hematopoiesis and Pre-mRNA Splicing In Vivo

      Shirai, C. L., Ley, J. N., White, B. S., Kim, S., Tibbitts, J., Shao, J., Ndonwi, M., Wadugu, B., Duncavage, E. J., Okeyo-Owuor, T., Liu, T., Griffith, M., McGrath, S., Magrini, V., Fulton, R. S., Fronick, C., O'Laughlin, M., Graubert, T. A. & Walter, M. J., May 11 2015, In: Cancer Cell. 27, 5, p. 631-643 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      194 Scopus citations

    • Optimizing Cancer Genome Sequencing and Analysis

      Griffith, M., Miller, C. A., Griffith, O. L., Krysiak, K., Skidmore, Z. L., Ramu, A., Walker, J. R., Dang, H. X., Trani, L., Larson, D. E., Demeter, R. T., Wendl, M. C., McMichael, J. F., Austin, R. E., Magrini, V., McGrath, S. D., Ly, A., Kulkarni, S., Cordes, M. G., Fronick, C. C., & 7 othersFulton, R. S., Maher, C. A., Ding, L., Klco, J. M., Mardis, E. R., Ley, T. J. & Wilson, R. K., Sep 23 2015, In: Cell Systems. 1, 3, p. 210-223 14 p., 35.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      131 Scopus citations

    • Patterns and functional implications of rare germline variants across 12 cancer types

      Lu, C., Xie, M., Wendl, M. C., Wang, J., McLellan, M. D., Leiserson, M. D. M., Huang, K. L., Wyczalkowski, M. A., Jayasinghe, R., Banerjee, T., Ning, J., Tripathi, P., Zhang, Q., Niu, B., Ye, K., Schmidt, H. K., Fulton, R. S., McMichael, J. F., Batra, P., Kandoth, C., & 23 othersBharadwaj, M., Koboldt, D. C., Miller, C. A., Kanchi, K. L., Eldred, J. M., Larson, D. E., Welch, J. S., You, M., Ozenberger, B. A., Govindan, R., Walter, M. J., Ellis, M. J., Mardis, E. R., Graubert, T. A., Dipersio, J. F., Ley, T. J., Wilson, R. K., Goodfellow, P. J., Raphael, B. J., Chen, F., Johnson, K. J., Parvin, J. D. & Ding, L., Dec 22 2015, In: Nature communications. 6, 10086.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      182 Scopus citations

    • Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia

      Wong, T. N., Ramsingh, G., Young, A. L., Miller, C. A., Touma, W., Welch, J. S., Lamprecht, T. L., Shen, D., Hundal, J., Fulton, R. S., Heath, S., Baty, J. D., Klco, J. M., Ding, L., Mardis, E. R., Westervelt, P., Dipersio, J. F., Walter, M. J., Graubert, T. A., Ley, T. J., & 3 othersDruley, T. E., Link, D. C. & Wilson, R. K., Feb 26 2015, In: Nature. 518, 7540, p. 552-555 4 p.

      Research output: Contribution to journal › Article › peer-review

      523 Scopus citations

    • TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits

      Diogo, D., Bastarache, L., Liao, K. P., Graham, R. R., Fulton, R. S., Greenberg, J. D., Eyre, S., Bowes, J., Cui, J., Lee, A., Pappas, D. A., Kremer, J. M., Barton, A., Coenen, M. J. H., Franke, B., Kiemeney, L. A., Mariette, X., Richard-Miceli, C., Canhão, H., Fonseca, J. E., & 34 othersDe Vries, N., Tak, P. P., Crusius, J. B. A., Nurmohamed, M. T., Kurreeman, F., Mikuls, T. R., Okada, Y., Stahl, E. A., Larson, D. E., Deluca, T. L., O'Laughlin, M., Fronick, C. C., Fulton, L. L., Kosoy, R., Ransom, M., Bhangale, T. R., Ortmann, W., Cagan, A., Gainer, V., Karlson, E. W., Kohane, I., Murphy, S. N., Martin, J., Zhernakova, A., Klareskog, L., Padyukov, L., Worthington, J., Mardis, E. R., Seldin, M. F., Gregersen, P. K., Behrens, T., Raychaudhuri, S., Denny, J. C. & Plenge, R. M., Apr 7 2015, In: PloS one. 10, 4, e0122271.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      92 Scopus citations

    • Whole exome sequencing reveals the order of genetic changes during malignant transformation and metastasis in a single patient with NF1-plexiform neurofibroma

      Hirbe, A. C., Dahiya, S., Miller, C. A., Li, T., Fulton, R. S., Zhang, X., McDonald, S., DeSchryver, K., Duncavage, E. J., Walrath, J., Reilly, K. M., Abel, H. J., Pekmezci, M., Perry, A., Ley, T. J. & Gutmann, D. H., Sep 15 2015, In: Clinical Cancer Research. 21, 18, p. 4201-4211 11 p.

      Research output: Contribution to journal › Article › peer-review

      32 Scopus citations
    • 2014

      A dominant mutation in hexokinase 1 (HK1) causes retinitis pigmentosa

      Sullivan, L. S., Koboldt, D. C., Bowne, S. J., Lang, S., Blanton, S. H., Cadena, E., Avery, C. E., Lewis, R. A., Webb-Jones, K., Wheaton, D. H., Birch, D. G., Coussa, R., Ren, H., Lopez, I., Chakarova, C., Koenekoop, R. K., Garcia, C. A., Fulton, R. S., Wilson, R. K., Weinstock, G. M., & 1 othersDaiger, S. P., Sep 4 2014, In: Investigative Ophthalmology and Visual Science. 55, 11, p. 7147-7158 12 p.

      Research output: Contribution to journal › Article › peer-review

      39 Scopus citations

    • Ancestry estimation and control of population stratification for sequence-based association studies

      Wang, C., Zhan, X., Bragg-Gresham, J., Kang, H. M., Stambolian, D., Chew, E. Y., Branham, K. E., Heckenlively, J., Fulton, R., Wilson, R. K., Mardis, E. R., Lin, X., Swaroop, A., Zöllner, S. & Abecasis, G. R., Apr 2014, In: Nature Genetics. 46, 4, p. 409-415 7 p.

      Research output: Contribution to journal › Article › peer-review

      89 Scopus citations

    • Application of next-generation sequencing to identify genes and mutations causing autosomal dominant retinitis pigmentosa (adRP)

      Daiger, S. P., Bowne, S. J., Sullivan, L. S., Blanton, S. H., Weinstock, G. M., Koboldt, D. C., Fulton, R. S., Larsen, D., Humphries, P., Humphries, M. M., Pierce, E. A., Chen, R. & Li, Y., 2014, In: Advances in Experimental Medicine and Biology. 801, p. 123-129 7 p.

      Research output: Contribution to journal › Article › peer-review

      29 Scopus citations

    • C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma

      Parker, M., Mohankumar, K. M., Punchihewa, C., Weinlich, R., Dalton, J. D., Li, Y., Lee, R., Tatevossian, R. G., Phoenix, T. N., Thiruvenkatam, R., White, E., Tang, B., Orisme, W., Gupta, K., Rusch, M., Chen, X., Li, Y., Nagahawhatte, P., Hedlund, E., Finkelstein, D., & 29 othersWu, G., Shurtleff, S., Easton, J., Boggs, K., Yergeau, D., Vadodaria, B., Mulder, H. L., Becksford, J., Gupta, P., Huether, R., Ma, J., Song, G., Gajjar, A., Merchant, T., Boop, F., Smith, A. A., Ding, L., Lu, C., Ochoa, K., Zhao, D., Fulton, R. S., Fulton, L. L., Mardis, E. R., Wilson, R. K., Downing, J. R., Green, D. R., Zhang, J., Ellison, D. W. & Gilbertson, R. J., 2014, In: Nature. 506, 7489, p. 451-455 5 p.

      Research output: Contribution to journal › Article › peer-review

      453 Scopus citations

    • Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice

      Lu, E. P., McLellan, M., Ding, L., Fulton, R., Mardis, E. R., Wilson, R. K., Miller, C. A., Westervelt, P., DiPersio, J. F., Link, D. C., Walter, M. J., Ley, T. J. & Graubert, T. A., Dec 18 2014, In: Blood. 124, 26, p. 3887-3895 9 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      18 Scopus citations

    • CDNA hybrid capture improves transcriptome analysis on low-input and archived samples

      Cabanski, C. R., Magrini, V., Griffith, M., Griffith, O. L., McGrath, S., Zhang, J., Walker, J., Ly, A., Demeter, R., Fulton, R. S., Pong, W. W., Gutmann, D. H., Govindan, R., Mardis, E. R. & Maher, C. A., Jul 2014, In: Journal of Molecular Diagnostics. 16, 4, p. 440-451 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      31 Scopus citations

    • Clonal Architecture of Secondary Acute Myeloid Leukemia Defined by Single-Cell Sequencing

      Hughes, A. E. O., Magrini, V., Demeter, R., Miller, C. A., Fulton, R., Fulton, L. L., Eades, W. C., Elliott, K., Heath, S., Westervelt, P., Ding, L., Conrad, D. F., White, B. S., Shao, J., Link, D. C., DiPersio, J. F., Mardis, E. R., Wilson, R. K., Ley, T. J., Walter, M. J., & 1 othersGraubert, T. A., Jul 2014, In: PLoS genetics. 10, 7, e1004462.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      98 Scopus citations

    • Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network

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      Open Access
      3553 Scopus citations

    • Functional heterogeneity of genetically defined subclones in acute myeloid leukemia

      Klco, J. M., Spencer, D. H., Miller, C. A., Griffith, M., Lamprecht, T. L., O'Laughlin, M., Fronick, C., Magrini, V., Demeter, R. T., Fulton, R. S., Eades, W. C., Link, D. C., Graubert, T. A., Walter, M. J., Mardis, E. R., Dipersio, J. F., Wilson, R. K. & Ley, T. J., Mar 17 2014, In: Cancer Cell. 25, 3, p. 379-392 14 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      283 Scopus citations

    • Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences

      Colonna, V., Ayub, Q., Chen, Y., Pagani, L., Luisi, P., Pybus, M., Garrison, E., Xue, Y., Tyler-Smith, C., Abecasis, G. R., Auton, A., Brooks, L. D., Depristo, M. A., Durbin, R. M., Handsaker, R. E., Kang, H. M., Marth, G. T., McVean, G., Altshuler, D. M., Durbin, R. M., & 685 othersAbecasis, G. R., Bentley, D. R., Chakravarti, A., Clark, A. G., Donnelly, P., Eichler, E. E., Flicek, P., Gabriel, S. B., Gibbs, R. A., Green, E. D., Hurles, M. E., Knoppers, B. M., Korbel, J. O., Lander, E. S., Lee, C., Lehrach, H., Mardis, E. R., Marth, G. T., McVean, G. A., Nickerson, D. A., Schmidt, J. P., Sherry, S. T., Wang, J., Wilson, R. K., Gibbs, R. A., Dinh, H., Kovar, C., Lee, S., Lewis, L., Muzny, D., Reid, J., Wang, M., Wang, J., Fang, X., Guo, X., Jian, M., Jiang, H., Jin, X., Li, G., Li, J., Li, Y., Li, Z., Liu, X., Lu, Y., Ma, X., Su, Z., Tai, S., Tang, M., Wang, B., Wang, G., Wu, H., Wu, R., Yin, Y., Zhang, W., Zhao, J., Zhao, M., Zheng, X., Zhou, Y., Lander, E. S., Altshuler, D. M., Gabriel, S. B., Gupta, N., Flicek, P., Clarke, L., Leinonen, R., Smith, R. E., Zheng-Bradley, X., Bentley, D. R., Grocock, R., Humphray, S., James, T., Kingsbury, Z., Lehrach, H., Sudbrak, R., Albrecht, M. W., Amstislavskiy, V. S., Borodina, T. A., Lienhard, M., Mertes, F., Sultan, M., Timmermann, B., Yaspo, M. L., Sherry, S. T., McVean, G. A., Mardis, E. R., Wilson, R. K., Fulton, L., Fulton, R., Weinstock, G. M., Durbin, R. M., Balasubramaniam, S., Burton, J., Danecek, P., Keane, T. M., Kolb-Kokocinski, A., McCarthy, S., Stalker, J., Quail, M., Schmidt, J. P., Davies, C. J., Gollub, J., Webster, T., Wong, B., Zhan, Y., Auton, A., Gibbs, R. A., Yu, F., Bainbridge, M., Challis, D., Evani, U. S., Lu, J., Muzny, D., Nagaswamy, U., Reid, J., Sabo, A., Wang, Y., Yu, J., Wang, J., Coin, L. J., Fang, L., Guo, X., Jin, X., Li, G., Li, Q., Li, Y., Li, Z., Lin, H., Liu, B., Luo, R., Qin, N., Shao, H., Wang, B., Xie, Y., Ye, C., Yu, C., Zhang, F., Zheng, H., Zhu, H., Marth, G. T., Garrison, E. P., Kural, D., Lee, W. P., Leong, W. F., Ward, A. N., Wu, J., Zhang, M., Lee, C., Griffin, L., Hsieh, C. H., Mills, R. E., Shi, X., von Grotthuss, M., Zhang, C., Daly, M. J., Depristo, M. A., Altshuler, D. M., Banks, E., Bhatia, G., Carneiro, M. O., Del Angel, G., Gabriel, S. B., Genovese, G., Gupta, N., Handsaker, R. E., Hartl, C., Lander, E. S., McCarroll, S. A., Nemesh, J. C., Poplin, R. E., Schaffner, S. F., Shakir, K., Yoon, S. C., Lihm, J., Makarov, V., Jin, H., Kim, W., Kim, K. C., Korbel, J. O., Rausch, T., Flicek, P., Beal, K., Clarke, L., Cunningham, F., Herrero, J., McLaren, W. M., Ritchie, G. R., Smith, R. E., Zheng-Bradley, X., Clark, A. G., Gottipati, S., Keinan, A., Rodriguez-Flores, J. L., Sabeti, P. C., Grossman, S. R., Tabrizi, S., Tariyal, R., Cooper, D. N., Ball, E. V., Stenson, P. D., Bentley, D. R., Barnes, B., Bauer, M., Cheetham, R., Cox, T., Eberle, M., Humphray, S., Kahn, S., Murray, L., Peden, J., Shaw, R., Ye, K., Batzer, M. A., Konkel, M. K., Walker, J. A., Macarthur, D. G., Lek, M., Sudbrak, R., Amstislavskiy, V. S., Herwig, R., Shriver, M. D., Bustamante, C. D., Byrnes, J. K., De La Vega, F. M., Gravel, S., Kenny, E. E., Kidd, J. M., Lacroute, P., Maples, B. K., Moreno-Estrada, A., Zakharia, F., Halperin, E., Baran, Y., Craig, D. W., Christoforides, A., Homer, N., Izatt, T., Kurdoglu, A. A., Sinari, S. A., Squire, K., Sherry, S. T., Xiao, C., Sebat, J., Bafna, V., Ye, K., Burchard, E. G., Hernandez, R. D., Gignoux, C. R., Haussler, D., Katzman, S. J., Kent, W. J., Howie, B., Ruiz-Linares, A., Dermitzakis, E. T., Lappalainen, T., Devine, S. E., Liu, X., Maroo, A., Tallon, L. J., Rosenfeld, J. A., Michelson, L. P., Anderson, P., Angius, A., Bigham, A., Blackwell, T., Busonero, F., Cucca, F., Fuchsberger, C., Jones, C., Li, Y., Lyons, R., Maschio, A., Porcu, E., Reinier, F., Sanna, S., Schlessinger, D., Sidore, C., Tan, A., Trost, M. K., Awadalla, P., Hodgkinson, A., Lunter, G., McVean, G. A., Marchini, J. L., Myers, S., Churchhouse, C., Delaneau, O., Gupta-Hinch, A., Iqbal, Z., Mathieson, I., Rimmer, A., Xifara, D. K., Oleksyk, T. K., Fu, Y., Liu, X., Xiong, M., Jorde, L., Witherspoon, D., Xing, J., Browning, B. L., Alkan, C., Hajirasouliha, I., Hormozdiari, F., Ko, A., Sudmant, P. H., Mardis, E. R., Chen, K., Chinwalla, A., Ding, L., Dooling, D., Koboldt, D. C., McLellan, M. D., Wallis, J. W., Wendl, M. C., Zhang, Q., Durbin, R. M., Hurles, M. E., Tyler-Smith, C., Albers, C. A., Ayub, Q., Balasubramaniam, S., Chen, Y., Coffey, A. J., Colonna, V., Danecek, P., Huang, N., Jostins, L., Keane, T. M., Li, H., McCarthy, S., Scally, A., Stalker, J., Walter, K., Xue, Y., Zhang, Y., Gerstein, M. B., Abyzov, A., Balasubramanian, S., Chen, J., Clarke, D., Fu, Y., Habegger, L., Harmanci, A. O., Jin, M., Khurana, E., Mu, X. J., Sisu, C., Li, Y., Luo, R., Zhu, H., Lee, C., Griffin, L., Hsieh, C. H., Mills, R. E., Shi, X., von Grotthuss, M., Zhang, C., Marth, G. T., Garrison, E. P., Kural, D., Lee, W. P., Ward, A. N., Wu, J., Zhang, M., McCarroll, S. A., Altshuler, D. M., Banks, E., Del Angel, G., Genovese, G., Handsaker, R. E., Hartl, C., Nemesh, J. C., Shakir, K., Yoon, S. C., Lihm, J., Makarov, V., Degenhardt, J., Flicek, P., Clarke, L., Smith, R. E., Zheng-Bradley, X., Korbel, J. O., Rausch, T., Stütz, A. M., Bentley, D. R., Barnes, B., Cheetham, R., Eberle, M., Humphray, S., Kahn, S., Murray, L., Shaw, R., Ye, K., Batzer, M. A., Konkel, M. K., Walker, J. A., Lacroute, P., Craig, D. W., Homer, N., Church, D., Xiao, C., Sebat, J., Bafna, V., Michaelson, J. J., Ye, K., Devine, S. E., Liu, X., Maroo, A., Tallon, L. J., Lunter, G., McVean, G. A., Iqbal, Z., Witherspoon, D., Xing, J., Eichler, E. E., Alkan, C., Hajirasouliha, I., Hormozdiari, F., Ko, A., Sudmant, P. H., Chen, K., Chinwalla, A., Ding, L., McLellan, M. D., Wallis, J. W., Hurles, M. E., Blackburne, B., Li, H., Lindsay, S. J., Ning, Z., Scally, A., Walter, K., Zhang, Y., Gerstein, M. B., Abyzov, A., Chen, J., Clarke, D., Khurana, E., Mu, X. J., Sisu, C., Gibbs, R. A., Yu, F., Bainbridge, M., Challis, D., Evani, U. S., Kovar, C., Lewis, L., Lu, J., Muzny, D., Nagaswamy, U., Reid, J., Sabo, A., Yu, J., Guo, X., Li, Y., Wu, R., Marth, G. T., Garrison, E. P., Leong, W. F., Ward, A. N., Del Angel, G., Depristo, M. A., Gabriel, S. B., Gupta, N., Hartl, C., Poplin, R. E., Clark, A. G., Rodriguez-Flores, J. L., Flicek, P., Clarke, L., Smith, R. E., Zheng-Bradley, X., Macarthur, D. G., Bustamante, C. D., Gravel, S., Craig, D. W., Christoforides, A., Homer, N., Izatt, T., Sherry, S. T., Xiao, C., Dermitzakis, E., Abecasis, G. R., Kang, H. M., McVean, G. A., Mardis, E. R., Dooling, D., Fulton, L., Fulton, R., Koboldt, D. C., Durbin, R. M., Balasubramaniam, S., Keane, T. M., McCarthy, S., Stalker, J., Gerstein, M. B., Balasubramanian, S., Habegger, L., Garrison, E. P., Gibbs, R. A., Bainbridge, M., Muzny, D., Yu, F., Yu, J., Del Angel, G., Handsaker, R. E., Makarov, V., Rodriguez-Flores, J. L., Jin, H., Kim, W., Kim, K. C., Flicek, P., Beal, K., Clarke, L., Cunningham, F., Herrero, J., McLaren, W. M., Ritchie, G. R., Zheng-Bradley, X., Tabrizi, S., Macarthur, D. G., Lek, M., Bustamante, C. D., De La Vega, F. M., Craig, D. W., Kurdoglu, A. A., Lappalainen, T., Rosenfeld, J. A., Michelson, L. P., Awadalla, P., Hodgkinson, A., McVean, G. A., Chen, K., Tyler-Smith, C., Chen, Y., Colonna, V., Frankish, A., Harrow, J., Xue, Y., Gerstein, M. B., Abyzov, A., Balasubramanian, S., Chen, J., Clarke, D., Fu, Y., Harmanci, A. O., Jin, M., Khurana, E., Mu, X. J., Sisu, C., Gibbs, R. A., Kovar, C., Kalra, D., Hale, W., Fowler, G., Muzny, D., Reid, J., Wang, J., Guo, X., Li, G., Li, Y., Zheng, X., Altshuler, D. M., Flicek, P., Clarke, L., Barker, J., Kelman, G., Kulesha, E., Leinonen, R., McLaren, W. M., Radhakrishnan, R., Roa, A., Smirnov, D., Smith, R. E., Streeter, I., Toneva, I., Vaughan, B., Zheng-Bradley, X., Bentley, D. 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D., Sandoval, K., Su, Y., Sudbrak, R., Tian, Z., Timmermann, B., Tishkoff, S., Toji, L. H., Tyler-Smith, C., Via, M., Wang, Y., Yang, H., Yang, L., Zhu, J., Bodmer, W., Bedoya, G., Ruiz-Linares, A., Ming, C. Z., Yang, G., You, C. J., Peltonen, L., Garcia-Montero, A., Orfao, A., Dutil, J., Martinez-Cruzado, J. C., Oleksyk, T. K., Brooks, L. D., Felsenfeld, A. L., McEwen, J. E., Clemm, N. C., Duncanson, A., Dunn, M., Green, E. D., Guyer, M. S. & Peterson, J. L., Jun 30 2014, In: Genome biology. 15, 6, R88.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      51 Scopus citations

    • Integrated analysis of germline and somatic variants in ovarian cancer

      Kanchi, K. L., Johnson, K. J., Lu, C., McLellan, M. D., Leiserson, M. D. M., Wendl, M. C., Zhang, Q., Koboldt, D. C., Xie, M., Kandoth, C., McMichael, J. F., Wyczalkowski, M. A., Larson, D. E., Schmidt, H. K., Miller, C. A., Fulton, R. S., Spellman, P. T., Mardis, E. R., Druley, T. E., Graubert, T. A., & 4 othersGoodfellow, P. J., Raphael, B. J., Wilson, R. K. & Ding, L., Jan 22 2014, In: Nature communications. 5, 3156.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      210 Scopus citations

    • Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel

      Delaneau, O., Marchini, J., McVeanh, G. A., Donnelly, P., Lunter, G., Marchini, J. L., Myers, S., Gupta-Hinch, A., Iqbal, Z., Mathieson, I., Rimmer, A., Xifara, D. K., Kerasidou, A., Churchhouse, C., Altshuler, D. M., Gabriel, S. B., Lander, E. S., Gupta, N., Daly, M. J., DePristo, M. A., & 363 othersBanks, E., Bhatia, G., Carneiro, M. O., Del Angel, G., Genovese, G., Handsaker, R. E., Hartl, C., McCarroll, S. A., Nemesh, J. C., Poplin, R. E., Schaffner, S. F., Shakir, K., Sabeti, P. C., Grossman, S. R., Tabrizi, S., Tariyal, R., Li, H., Reich, D., Durbin, R. M., Hurles, M. E., Balasubramaniam, S., Burton, J., Danecek, P., Keane, T. M., Kolb-Kokocinski, A., McCarthy, S., Stalker, J., Quail, M., Ayub, Q., Chen, Y., Coffey, A. J., Colonna, V., Huang, N., Jostins, L., Scally, A., Walter, K., Xue, Y., Zhang, Y., Blackburne, B., Lindsay, S. J., Ning, Z., Frankish, A., Harrow, J., Chris, T. S., Abecasis, G. R., Kang, H. M., Anderson, P., Blackwell, T., Busonero, F., Fuchsberger, C., Jun, G., Maschio, A., Porcu, E., Sidore, C., Tan, A., Trost, M. K., Bentley, D. R., Grocock, R., Humphray, S., James, T., Kingsbury, Z., Bauer, M., Cheetham, R. K., Cox, T., Eberle, M., Murray, L., Shaw, R., Chakravarti, A., Clark, A. G., Keinan, A., Rodriguez-Flores, J. L., De LaVega, F. M., Degenhardt, J., Eichler, E. E., Flicek, P., Clarke, L., Leinonen, R., Smith, R. E., Zheng-Bradley, X., Beal, K., Cunningham, F., Herrero, J., McLaren, W. M., Ritchie, G. R. S., Barker, J., Kelman, G., Kulesha, E., Radhakrishnan, R., Roa, A., Smirnov, D., Streeter, I., Toneva, I., Gibbs, R. A., Dinh, H., Kovar, C., Lee, S., Lewis, L., Muzny, D., Reid, J., Wang, M., Yu, F., Bainbridge, M., Challis, D., Evani, U. S., Lu, J., Nagaswamy, U., Sabo, A., Wang, Y., Yu, J., Fowler, G., Hale, W., Kalra, D., Green, E. D., Knoppers, B. M., Korbel, J. O., Rausch, T., Sttz, A. M., Lee, C., Griffin, L., Hsieh, C. H., Mills, R. 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      Research output: Contribution to journal › Article › peer-review

      Open Access
      252 Scopus citations

    • Integration of sequence data from a consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene

      Okada, Y., Diogo, D., Greenberg, J. D., Mouassess, F., Achkar, W. A. L., Fulton, R. S., Denny, J. C., Gupta, N., Mirel, D., Gabriel, S., Li, G., Kremer, J. M., Pappas, D. A., Carroll, R. J., Eyler, A. E., Trynka, G., Stahl, E. A., Cui, J., Saxena, R., Coenen, M. J. H., & 28 othersGuchelaar, H. J., Huizinga, T. W. J., Dieudé, P., Mariette, X., Barton, A., Canhão, H., Fonseca, J. E., De Vries, N., Tak, P. P., Moreland, L. W., Bridges, S. L., Miceli-Richard, C., Choi, H. K., Kamatani, Y., Galan, P., Lathrop, M., Raj, T., De Jager, P. L., Raychaudhuri, S., Worthington, J., Padyukov, L., Klareskog, L., Siminovitch, K. A., Gregersen, P. K., Mardis, E. R., Arayssi, T., Kazkaz, L. A. & Plenge, R. M., Feb 10 2014, In: PloS one. 9, 2, e87645.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      24 Scopus citations

    • Mammalian y chromosomes retain widely expressed dosage-sensitive regulators

      Bellott, D. W., Hughes, J. F., Skaletsky, H., Brown, L. G., Pyntikova, T., Cho, T. J., Koutseva, N., Zaghlul, S., Graves, T., Rock, S., Kremitzki, C., Fulton, R. S., Dugan, S., Ding, Y., Morton, D., Khan, Z., Lewis, L., Buhay, C., Wang, Q., Watt, J., & 9 othersHolder, M., Lee, S., Nazareth, L., Rozen, S., Muzny, D. M., Warren, W. C., Gibbs, R. A., Wilson, R. K. & Page, D. C., 2014, In: Nature. 508, 7497, p. 494-499 6 p.

      Research output: Contribution to journal › Article › peer-review

      395 Scopus citations

    • Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin

      The Cancer Genome Atlas Research Network, Aug 14 2014, In: Cell. 158, 4, p. 929-944 16 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1005 Scopus citations

    • RB1 gene inactivation by chromothripsis in human retinoblastoma

      McEvoy, J., Nagahawatte, P., Finkelstein, D., Richards-Yutz, J., Valentine, M., Ma, J., Mullighan, C., Song, G., Chen, X., Wilson, M., Brennan, R., Pounds, S., Becksfort, J., Huether, R., Lu, C., Fulton, R. S., Fulton, L. L., Hong, X., Dooling, D. J., Ochoa, K., & 7 othersMardis, E. R., Wilson, R. K., Easton, J., Zhang, J., Downing, J. R., Ganguly, A. & Dyer, M. A., 2014, In: Oncotarget. 5, 2, p. 438-450 13 p.

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      Open Access
      74 Scopus citations

    • Re-sequencing Expands Our Understanding of the Phenotypic Impact of Variants at GWAS Loci

      Service, S. K., Teslovich, T. M., Fuchsberger, C., Ramensky, V., Yajnik, P., Koboldt, D. C., Larson, D. E., Zhang, Q., Lin, L., Welch, R., Ding, L., McLellan, M. D., O'Laughlin, M., Fronick, C., Fulton, L. L., Magrini, V., Swift, A., Elliott, P., Jarvelin, M. R., Kaakinen, M., & 14 othersMcCarthy, M. I., Peltonen, L., Pouta, A., Bonnycastle, L. L., Collins, F. S., Narisu, N., Stringham, H. M., Tuomilehto, J., Ripatti, S., Fulton, R. S., Sabatti, C., Wilson, R. K., Boehnke, M. & Freimer, N. B., Jan 2014, In: PLoS genetics. 10, 1, e1004147.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      44 Scopus citations

    • Sequencing the mouse y chromosome reveals convergent gene acquisition and amplification on both sex chromosomes

      Soh, Y. Q. S., Alföldi, J., Pyntikova, T., Brown, L. G., Graves, T., Minx, P. J., Fulton, R. S., Kremitzki, C., Koutseva, N., Mueller, J. L., Rozen, S., Hughes, J. F., Owens, E., Womack, J. E., Murphy, W. J., Cao, Q., De Jong, P., Warren, W. C., Wilson, R. K., Skaletsky, H., & 1 othersPage, D. C., Nov 6 2014, In: Cell. 159, 4, p. 800-813 14 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      197 Scopus citations

    • Single haplotype assembly of the human genome from a hydatidiform mole

      Steinberg, K. M., Schneider, V. A., Graves-Lindsay, T. A., Fulton, R. S., Agarwala, R., Huddleston, J., Shiryev, S. A., Morgulis, A., Surti, U., Warren, W. C., Church, D. M., Eichler, E. E. & Wilson, R. K., Dec 1 2014, In: Genome research. 24, 12, p. 2066-2076 11 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      80 Scopus citations

    • Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia

      Roberts, K. G., Li, Y., Payne-Turner, D., Harvey, R. C., Yang, Y. L., Pei, D., McCastlain, K., Ding, L., Lu, C., Song, G., Ma, J., Becksfort, J., Rusch, M., Chen, S. C., Easton, J., Cheng, J., Boggs, K., Santiago-Morales, N., Iacobucci, I., Fulton, R. S., & 54 othersWen, J., Valentine, M., Cheng, C., Paugh, S. W., Devidas, M., Chen, I. M., Reshmi, S., Smith, A., Hedlund, E., Gupta, P., Nagahawatte, P., Wu, G., Chen, X., Yergeau, D., Vadodaria, B., Mulder, H., Winick, N. J., Larsen, E. C., Carroll, W. L., Heerema, N. A., Carroll, A. J., Grayson, G., Tasian, S. K., Moore, A. S., Keller, F., Frei-Jones, M., Whitlock, J. A., Raetz, E. A., White, D. L., Hughes, T. P., Guidry Auvil, J. M., Smith, M. A., Marcucci, G., Bloomfield, C. D., Mrózek, K., Kohlschmidt, J., Stock, W., Kornblau, S. M., Konopleva, M., Paietta, E., Pui, C. H., Jeha, S., Relling, M. V., Evans, W. E., Gerhard, D. S., Gastier-Foster, J. M., Mardis, E., Wilson, R. K., Loh, M. L., Downing, J. R., Hunger, S. P., Willman, C. L., Zhang, J. & Mullighan, C. G., Sep 11 2014, In: New England Journal of Medicine. 371, 11, p. 1005-1015 11 p.

      Research output: Contribution to journal › Article › peer-review

      934 Scopus citations

    • The common marmoset genome provides insight into primate biology and evolution

      Worley, K. C., Warren, W. C., Rogers, J., Locke, D., Muzny, D. M., Mardis, E. R., Weinstock, G. M., Tardif, S. D., Aagaard, K. M., Archidiacono, N., Arul Rayan, N., Batzer, M. A., Beal, K., Brejova, B., Capozzi, O., Capuano, S. B., Casola, C., Chandrabose, M. M., Cree, A., Diep Dao, M., & 91 othersDe Jong, P. J., Cruz-Herrera del Rosario, R., Delehaunty, K. D., Dinh, H. H., Eichler, E. E., Fitzgerald, S., Flicek, P., Fontenot, C. C., Fowler, R. G., Fronick, C., Fulton, L. A., Fulton, R. S., Gabisi, R. A., Gerlach, D., Graves, T. A., Gunaratne, P. H., Hahn, M. W., Haig, D., Han, Y., Harris, R. A., Herrero, J., Hillier, L. D. W., Hubley, R., Hughes, J. F., Hume, J., Jhangiani, S. N., Jorde, L. B., Joshi, V., Karakor, E., Konkel, M. K., Kosiol, C., LKovar, C., Kriventseva, E. V., Lee, S. L., Lewis, L. R., Liu, Y. S., Lopez, J., Lopez-Otin, C., Lorente-Galdos, B., Mansfield, K. G., Marques-Bonet, T., Minx, P., Misceo, D., Moncrieff, J. S., Morgan, M. B., Nazareth, L. V., Newsham, I., Nguyen, N. B., Okwuonu, G. O., Prabhakar, S., Perales, L., Pu, L. L., Puente, X. S., Quesada, V., Ranck, M. C., Raney, B. J., Raveendran, M., Deiros, D. R., Rocchi, M., Rodriguez, D., Ross, C., Ruffier, M., Ruiz, S. J., Sajjadian, S., Santibanez, J., Schrider, D. R., Searle, S., Skaletsky, H., Soibam, B., Smit, A. F. A., Tennakoon, J. B., Tomaska, L., Ullmer, B., Vejnar, C. E., Ventura, M., Vilella, A. J., Vinar, T., Vogel, J. H., Walker, J. A., Wang, Q., Warner, C. M., Wildman, D. E., Witherspoon, D. J., Wright, R. A., Wu, Y., Xiao, W., Xing, J., Zdobnov, E. M., Zhu, B., Gibbs, R. A. & Wilson, R. K., Aug 2014, In: Nature Genetics. 46, 8, p. 850-857 8 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      165 Scopus citations

    • The DNA double-strand break response is abnormal in myeloblasts from patients with therapy-related acute myeloid leukemia

      Jacoby, M. A., De Jesus Pizarro, R. E., Shao, J., Koboldt, D. C., Fulton, R. S., Zhou, G., Wilson, R. K. & Walter, M. J., Jun 2014, In: Leukemia. 28, 6, p. 1242-1251 10 p.

      Research output: Contribution to journal › Article › peer-review

      29 Scopus citations

    • The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

      Wu, G., Diaz, A. K., Paugh, B. S., Rankin, S. L., Ju, B., Li, Y., Zhu, X., Qu, C., Chen, X., Zhang, J., Easton, J., Edmonson, M., Ma, X., Lu, C., Nagahawatte, P., Hedlund, E., Rusch, M., Pounds, S., Lin, T., Onar-Thomas, A., & 27 othersHuether, R., Kriwacki, R., Parker, M., Gupta, P., Becksfort, J., Wei, L., Mulder, H. L., Boggs, K., Vadodaria, B., Yergeau, D., Russell, J. C., Ochoa, K., Fulton, R. S., Fulton, L. L., Jones, C., Boop, F. A., Broniscer, A., Wetmore, C., Gajjar, A., Ding, L., Mardis, E. R., Wilson, R. K., Taylor, M. R., Downing, J. R., Ellison, D. W., Zhang, J. & Baker, S. J., May 2014, In: Nature Genetics. 46, 5, p. 444-450 7 p.

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      687 Scopus citations

    • The R882H DNMT3A Mutation Associated with AML Dominantly Inhibits Wild-Type DNMT3A by Blocking Its Ability to Form Active Tetramers

      Russler-Germain, D. A., Spencer, D. H., Young, M. A., Lamprecht, T. L., Miller, C. A., Fulton, R., Meyer, M. R., Erdmann-Gilmore, P., Townsend, R. R., Wilson, R. K. & Ley, T. J., Apr 14 2014, In: Cancer Cell. 25, 4, p. 442-454 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      300 Scopus citations
    • 2013

      Clonal diversity of recurrently mutated genes in myelodysplastic syndromes

      Walter, M. J., Shen, D., Shao, J., Ding, L., White, B., Kandoth, C., Miller, C. A., Niu, B., McLellan, M. D., Dees, N. D., Fulton, R., Elliot, K., Heath, S., Grillot, M., Westervelt, P., Link, D. C., DiPersio, J. F., Mardis, E., Ley, T. J., Wilson, R. K., & 1 othersGraubert, T. A., Jun 2013, In: Leukemia. 27, 6, p. 1275-1282 8 p.

      Research output: Contribution to journal › Article › peer-review

      232 Scopus citations

    • Endocrine-Therapy-Resistant ESR1 Variants Revealed by Genomic Characterization of Breast-Cancer-Derived Xenografts

      Li, S., Shen, D., Shao, J., Crowder, R., Liu, W., Prat, A., He, X., Liu, S., Hoog, J., Lu, C., Ding, L., Griffith, O. L., Miller, C., Larson, D., Fulton, R. S., Harrison, M., Mooney, T., McMichael, J. F., Luo, J., Tao, Y., & 35 othersGoncalves, R., Schlosberg, C., Hiken, J. F., Saied, L., Sanchez, C., Giuntoli, T., Bumb, C., Cooper, C., Kitchens, R. T., Lin, A., Phommaly, C., Davies, S. R., Zhang, J., Kavuri, M. S., McEachern, D., Dong, Y. Y., Ma, C., Pluard, T., Naughton, M., Bose, R., Suresh, R., McDowell, R., Michel, L., Aft, R., Gillanders, W., DeSchryver, K., Wilson, R. K., Wang, S., Mills, G. B., Gonzalez-Angulo, A., Edwards, J. R., Maher, C., Perou, C. M., Mardis, E. R. & Ellis, M. J., Sep 26 2013, In: Cell Reports. 4, 6, p. 1116-1130 15 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      452 Scopus citations

    • Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

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      3325 Scopus citations

    • Integrated genomic characterization of endometrial carcinoma

      Getz, G., Gabriel, S. B., Cibulskis, K., Lander, E., Sivachenko, A., Sougnez, C., Lawrence, M., Kandoth, C., Dooling, D., Fulton, R., Fulton, L., Kalicki-Veizer, J., McLellan, M. D., O'Laughlin, M., Schmidt, H., Wilson, R. K., Ye, K., Li, D., Ally, A., Balasundaram, M., & 256 othersBirol, I., Butterfield, Y. S. N., Carlsen, R., Carter, C., Chu, A., Chuah, E., Chun, H. J. E., Dhalla, N., Guin, R., Hirst, C., Holt, R. A., Jones, S. J. M., Lee, D., Li, H. I., Marra, M. A., Mayo, M., Moore, R. A., Mungall, A. J., Plettner, P., Schein, J. E., Sipahimalani, P., Tam, A., Varhol, R. J., Gordon Robertson, A., Cherniack, A. D., Pashtan, I., Saksena, G., Onofrio, R. C., Schumacher, S. E., Tabak, B., Carter, S. L., Hernandez, B., Gentry, J., Salvesen, H. B., Ardlie, K., Winckler, W., Beroukhim, R., Meyerson, M., Hadjipanayis, A., Lee, S., Mahadeshwar, H. S., Park, P., Protopopov, A., Ren, X., Seth, S., Song, X., Tang, J., Xi, R., Yang, L., Dong, Z., Kucherlapati, R., Chin, L., Zhang, J., Todd Auman, J., Balu, S., Bodenheimer, T., Buda, E., Neil Hayes, D., Hoyle, A. P., Jefferys, S. R., Jones, C. D., Meng, S., Mieczkowski, P. A., Mose, L. E., Parker, J. S., Perou, C. M., Roach, J., Yan, S., Simons, J. V., Soloway, M. G., Tan, D., Topal, M. D., Waring, S., Wu, J., Hoadley, K. A., Baylin, S. B., Bootwalla, M. S., Lai, P. H., Triche, T. J., Van Den Berg, D. J., Weisenberger, D. J., Laird, P. W., Shen, H., Cho, J., Dicara, D., Frazer, S., Heiman, D., Jing, R., Lin, P., Mallard, W., Stojanov, P., Voet, D., Zhang, H., Zou, L., Noble, M., Reynolds, S. M., Shmulevich, I., Arman Aksoy, B., Antipin, Y., Ciriello, G., Dresdner, G., Gao, J., Gross, B., Jacobsen, A., Ladanyi, M., Reva, B., Sander, C., Sinha, R., Onur Sumer, S., Taylor, B. S., Cerami, E., Weinhold, N., Schultz, N., Shen, R., Benz, S., Goldstein, T., Haussler, D., Ng, S., Szeto, C., Stuart, J., Benz, C. C., Yau, C., Zhang, W., Annala, M., Broom, B. M., Casasent, T. D., Ju, Z., Liang, H., Liu, G., Lu, Y., Unruh, A. K., Wakefield, C., Weinstein, J. N., Zhang, N., Liu, Y., Broaddus, R., Akbani, R., Mills, G. B., Adams, C., Barr, T., Black, A. D., Bowen, J., Deardurff, J., Frick, J., Gastier-Foster, J. M., Grossman, T., Harper, H. A., Hart-Kothari, M., Helsel, C., Hobensack, A., Kuck, H., Kneile, K., Leraas, K. M., Lichtenberg, T. M., McAllister, C., Pyatt, R. E., Ramirez, N. C., Tabler, T. R., Vanhoose, N., White, P., Wise, L., Zmuda, E., Barnabas, N., Berry-Green, C., Blanc, V., Boice, L., Button, M., Farkas, A., Green, A., MacKenzie, J., Nicholson, D., Kalloger, S. E., Blake Gilks, C., Karlan, B. Y., Lester, J., Orsulic, S., Borowsky, M., Cadungog, M., Czerwinski, C., Huelsenbeck-Dill, L., Iacocca, M., Petrelli, N., Rabeno, B., Witkin, G., Nemirovich-Danchenko, E., Potapova, O., Rotin, D., Berchuck, A., Birrer, M., Disaia, P., Monovich, L., Curley, E., Gardner, J., Mallery, D., Penny, R., Dowdy, S. C., Winterhoff, B., Dao, L., Gostout, B., Meuter, A., Teoman, A., Dao, F., Olvera, N., Bogomolniy, F., Garg, K., Soslow, R. A., Abramov, M., Bartlett, J. M. S., Kodeeswaran, S., Parfitt, J., Moiseenko, F., Clarke, B. A., Goodman, M. T., Carney, M. E., Matsuno, R. K., Fisher, J., Huang, M., Kimryn Rathmell, W., Thorne, L., Van Le, L., Dhir, R., Edwards, R., Elishaev, E., Zorn, K., Goodfellow, P. J., Mutch, D., Kahn, A. B., Bell, D. W., Pollock, P. M., Wang, C., Wheeler, D., Shinbrot, E., Gordon Robertson, A., Ding, L., Blake Gilks, C., Mardis, E. R., Ayala, B., Chu, A. L., Jensen, M. A., Kothiyal, P., Pihl, T. D., Pontius, J., Pot, D. A., Snyder, E. E., Srinivasan, D., Mills Shaw, K. R., Sheth, M., Davidsen, T., Eley, G., Ferguson, M. L., Yang, L., Guyer, M. S., Ozenberger, B. A., Sofia, H. J., Gordon Robertson, A. & Levine, D. A., 2013, In: Nature. 497, 7447, p. 67-73 7 p.

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      Open Access
      3038 Scopus citations

    • Integrative annotation of variants from 1092 humans: Application to cancer genomics

      1000 Genomes Project Consortium, Oct 4 2013, In: Science. 342, 6154, 1235587.

      Research output: Contribution to journal › Article › peer-review

      272 Scopus citations

    • Oil palm genome sequence reveals divergence of interfertile species in Old and New worlds

      Singh, R., Ong-Abdullah, M., Low, E. T. L., Manaf, M. A. A., Rosli, R., Nookiah, R., Ooi, L. C. L., Ooi, S. E., Chan, K. L., Halim, M. A., Azizi, N., Nagappan, J., Bacher, B., Lakey, N., Smith, S. W., He, D., Hogan, M., Budiman, M. A., Lee, E. K., Desalle, R., & 8 othersKudrna, D., Goicoechea, J. L., Wing, R. A., Wilson, R. K., Fulton, R. S., Ordway, J. M., Martienssen, R. A. & Sambanthamurthi, R., 2013, In: Nature. 500, 7462, p. 335-339 5 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
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    • Somatic neurofibromatosis type 1 (NF1) inactivation characterizes NF1-associated pilocytic astrocytoma

      Gutmann, D. H., McLellan, M. D., Hussain, I., Wallis, J. W., Fulton, L. L., Fulton, R. S., Magrini, V., Demeter, R., Wylie, T., Kandoth, C., Leonard, J. R., Guha, A., Miller, C. A., Ding, L. & Mardis, E. R., Mar 2013, In: Genome research. 23, 3, p. 431-439 9 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      80 Scopus citations