Robert Fulton

2024

Human whole-exome genotype data for Alzheimer’s disease

Leung, Y. Y., Naj, A. C., Chou, Y. F., Valladares, O., Schmidt, M., Hamilton-Nelson, K., Wheeler, N., Lin, H., Gangadharan, P., Qu, L., Clark, K., Kuzma, A. B., Lee, W. P., Cantwell, L., Nicaretta, H., van der Lee, S., English, A., Kalra, D., Muzny, D. & Skinner, E. & 121 others, Doddapeneni, H., Dinh, H., Hu, J., Santibanez, J., Jayaseelan, J., Worley, K., Gibbs, R. A., Lee, S., Dugan-Perez, S., Korchina, V., Nasser, W., Liu, X., Han, Y., Zhu, Y., Liu, Y., Khan, Z., Zhu, C., Sun, F. J., Jun, G. R., Chung, J., Farrell, J., Zhang, X., Banks, E., Gupta, N., Gabriel, S., Butkiewicz, M., Benchek, P., Smieszek, S., Song, Y., Vardarajan, B., Reitz, C., Reyes-Dumeyer, D., Tosto, G., De Jager, P. L., Barral, S., Ma, Y., Beiser, A., Liu, C. T., Dupuis, J., Lunetta, K., Cupples, L. A., Choi, S. H., Chen, Y., Mez, J., Vanderspek, A., Ikram, M. A., Ahmad, S., Faber, K., Foroud, T., Mlynarski, E., Schmidt, H., Schmidt, R., Kunkle, B., Rajabli, F., Beecham, G., Vance, J. M., Adams, L. D., Cuccaro, M., Mena, P., Booth, B. M., Renton, A., Goate, A., Marcora, E., Stine, A., Feolo, M., Launer, L. J., Koboldt, D. C., Wilson, R. K., van Duijn, C., Amin, N., Kapoor, M., Salerno, W., Bennett, D. A., Xia, L. C., Malamon, J., Mosley, T. H., Satizabal, C., Jan Bressler, B., Jian, X., Nato, A. Q., Horimoto, A. R., Wang, B., Psaty, B., Witten, D., Tsuang, D., Blue, E., Wijsman, E., Sohi, H., Nguyen, H., Bis, J. C., Rice, K., Brown, L., Dorschner, M., Saad, M., Navas, P., Nafikov, R., Thornton, T., Day, T., Haut, J., Sha, J., Zhang, N., Iqbal, T., Zhao, Y., Below, J. E., Larson, D. E., Appelbaum, E., Waligorski, J., Antonacci-Fulton, L., Fulton, R. S., Haines, J., Farrer, L., Seshadri, S., Brkanac, Z., Cruchaga, C., Pericak-Vance, M., Mayeux, R. P., Bush, W. S., Destefano, A., Martin, E., Schellenberg, G. D. & Wang, L. S., Dec 2024, In: Nature communications. 15, 1, 684.

Research output: Contribution to journal › Article › peer-review

Open Access

Single-cell T-cell receptor repertoire profiling in dogs

Hoang, M. H., Skidmore, Z. L., Rindt, H., Chu, S., Fisk, B., Foltz, J. A., Fronick, C., Fulton, R., Zhou, M., Bivens, N. J., Reinero, C. N., Fehniger, T. A., Griffith, M., Bryan, J. N. & Griffith, O. L., Dec 2024, In: Communications Biology. 7, 1, 484.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

2023

A draft human pangenome reference

Liao, W. W., Asri, M., Ebler, J., Doerr, D., Haukness, M., Hickey, G., Lu, S., Lucas, J. K., Monlong, J., Abel, H. J., Buonaiuto, S., Chang, X. H., Cheng, H., Chu, J., Colonna, V., Eizenga, J. M., Feng, X., Fischer, C., Fulton, R. S. & Garg, S. & 99 others, Groza, C., Guarracino, A., Harvey, W. T., Heumos, S., Howe, K., Jain, M., Lu, T. Y., Markello, C., Martin, F. J., Mitchell, M. W., Munson, K. M., Mwaniki, M. N., Novak, A. M., Olsen, H. E., Pesout, T., Porubsky, D., Prins, P., Sibbesen, J. A., Sirén, J., Tomlinson, C., Villani, F., Vollger, M. R., Antonacci-Fulton, L. L., Baid, G., Baker, C. A., Belyaeva, A., Billis, K., Carroll, A., Chang, P. C., Cody, S., Cook, D. E., Cook-Deegan, R. M., Cornejo, O. E., Diekhans, M., Ebert, P., Fairley, S., Fedrigo, O., Felsenfeld, A. L., Formenti, G., Frankish, A., Gao, Y., Garrison, N. A., Giron, C. G., Green, R. E., Haggerty, L., Hoekzema, K., Hourlier, T., Ji, H. P., Kenny, E. E., Koenig, B. A., Kolesnikov, A., Korbel, J. O., Kordosky, J., Koren, S., Lee, H. J., Lewis, A. P., Magalhães, H., Marco-Sola, S., Marijon, P., McCartney, A., McDaniel, J., Mountcastle, J., Nattestad, M., Nurk, S., Olson, N. D., Popejoy, A. B., Puiu, D., Rautiainen, M., Regier, A. A., Rhie, A., Sacco, S., Sanders, A. D., Schneider, V. A., Schultz, B. I., Shafin, K., Smith, M. W., Sofia, H. J., Abou Tayoun, A. N., Thibaud-Nissen, F., Tricomi, F. F., Wagner, J., Walenz, B., Wood, J. M. D., Zimin, A. V., Bourque, G., Chaisson, M. J. P., Flicek, P., Phillippy, A. M., Zook, J. M., Eichler, E. E., Haussler, D., Wang, T., Jarvis, E. D., Miga, K. H., Garrison, E., Marschall, T., Hall, I. M., Li, H. & Paten, B., May 11 2023, In: Nature. 617, 7960, p. 312-324 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

219 Scopus citations

Genomic landscape of TP53-mutated myeloid malignancies

Abel, H. J., Oetjen, K. A., Miller, C. A., Ramakrishnan, S. M., Day, R. B., Helton, N. M., Fronick, C. C., Fulton, R. S., Heath, S. E., Tarnawsky, S. P., Srivatsan, S. N., Duncavage, E. J., Schroeder, M. C., Payton, J. E., Spencer, D. H., Walter, M. J., Westervelt, P., DiPersio, J. F., Ley, T. J. & Link, D. C., Aug 16 2023, In: Blood Advances. 7, 16, p. 4586-4598 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Increased mutation and gene conversion within human segmental duplications

Human Pangenome Reference Consortium, Abel, H. J., Antonacci-Fulton, L. L., Fulton, R. S., Hall, I., Liao, W. W., Regier, A., Tomlinson, C. & Wang, T., May 11 2023, In: Nature. 617, 7960, p. 325-334 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Pan-conserved segment tags identify ultra-conserved sequences across assemblies in the human pangenome

Human Pangenome Reference Consortium, Aug 28 2023, In: Cell Reports Methods. 3, 8, 100543.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Pangenome graph construction from genome alignments with Minigraph-Cactus

Human Pangenome Reference Consortium, 2023, (Accepted/In press) In: Nature Biotechnology.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Scopus citations

Recombination between heterologous human acrocentric chromosomes

Human Pangenome Reference Consortium, Abel, H. J., Antonacci-Fulton, L. L., Fulton, R. S., Hall, I., Liao, W. W., Regier, A. & Wang, T., May 11 2023, In: Nature. 617, 7960, p. 335-343 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Ultra-Deep Sequencing Reveals the Mutational Landscape of Classical Hodgkin Lymphoma

Gomez, F., Fisk, B., McMichael, J. F., Mosior, M., Foltz, J. A., Skidmore, Z. L., Duncavage, E. J., Miller, C. A., Abel, H., Li, Y. S., Russler-Germain, D. A., Krysiak, K., Watkins, M. P., Ramirez, C. A., Schmidt, A., Rodrigues, F. M., Trani, L., Khanna, A., Wagner, J. A. & Fulton, R. S. & 11 others, Fronick, C. C., O'Laughlin, M. D., Schappe, T., Cashen, A. F., Mehta-Shah, N., Kahl, B. S., Walker, J., Bartlett, N. L., Griffith, M., Fehniger, T. A. & Griffith, O. L., Nov 2023, In: Cancer research communications. 3, 11, p. 2312-2330 19 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Utility of targeted gene sequencing to differentiate myeloid malignancies from other cytopenic conditions

DeZern, A. E., Goll, J. B., Lindsley, R. C., Bejar, R., Wilson, S. H., Hebert, D., Deeg, J., Zhang, L., Gore, S., Baghdadi, T. A., Maciejewski, J., Liu, J., Padron, E., Komrojki, R., Saber, W., Abel, G., Kroft, S. H., Harrington, A., Grimes, T. & Reed, H. & 5 others, Fulton, R. S., DiFronzo, N. L., Gillis, N., Sekeres, M. A. & Walter, M. J., Jul 25 2023, In: Blood Advances. 7, 14, p. 3749-3759 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

2022

Convergent Clonal Evolution of Signaling Gene Mutations Is a Hallmark of Myelodysplastic Syndrome Progression

Menssen, A. J., Khanna, A., Miller, C. A., Srivatsan, S. N., Chang, G. S., Shao, J., Robinson, J., O’Laughlin, M., Fronick, C. C., Fulton, R. S., Brendel, K., Heath, S. E., Saba, R., Welch, J. S., Spencer, D. H., Payton, J. E., Westervelt, P., DiPersio, J. F., Link, D. C. & Schuelke, M. J. & 4 others, Jacoby, M. A., Duncavage, E. J., Ley, T. J. & Walter, M. J., Jul 1 2022, In: Blood cancer discovery. 3, 4, p. 330-345 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Failure to Detect Mutations in U2AF1 due to Changes in the GRCh38 Reference Sequence

Miller, C. A., Walker, J. R., Jensen, T. L., Hooper, W. F., Fulton, R. S., Painter, J. S., Sekeres, M. A., Ley, T. J., Spencer, D. H., Goll, J. B. & Walter, M. J., Mar 2022, In: Journal of Molecular Diagnostics. 24, 3, p. 219-223 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Focal disruption of DNA methylation dynamics at enhancers in IDH-mutant AML cells

Wilson, E. R., Helton, N. M., Heath, S. E., Fulton, R., Payton, J. E., Welch, J., Walter, M., Westervelt, P., DiPersio, J. F., Link, D. C., Miller, C., Ley, T. J. & Spencer, D., Apr 2022, In: Leukemia. 36, 4, p. 935-945 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Genetic and Transcriptional Contributions to Relapse in Normal Karyotype Acute Myeloid Leukemia

Petti, A. A., Khan, S. M., Xu, Z., Helton, N., Fronick, C. C., Fulton, R., Ramakrishnan, S. M., Srivatsan, S. N., Heath, S. E., Westervelt, P., Payton, J. E., Walter, M. J., Link, D. C., DiPersio, J., Miller, C. & Ley, T. J., Jan 1 2022, In: Blood cancer discovery. 3, 1, p. 32-49 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Genomic and transcriptomic somatic alterations of hepatocellular carcinoma in non-cirrhotic livers

Skidmore, Z. L., Kunisaki, J., Lin, Y., Cotto, K. C., Barnell, E. K., Hundal, J., Krysiak, K., Magrini, V., Trani, L., Walker, J. R., Fulton, R., Brunt, E. M., Miller, C. A., Wilson, R. K., Mardis, E. R., Griffith, M., Chapman, W. & Griffith, O. L., Jun 2022, In: Cancer Genetics. 264-265, p. 90-99 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

IL-1β expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC function

Li, S., Yao, J. C., Oetjen, K. A., Krambs, J. R., Xia, J., Zhang, J., Schmidt, A. P., Helton, N. M., Fulton, R. S., Heath, S. E., Turnbull, I. R., Mbalaviele, G., Ley, T. J., Walter, M. J. & Link, D. C., Oct 6 2022, In: Blood. 140, 14, p. 1607-1620 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health

Stanford TDA, University of Connecticut TMC, University of Michigan TDA, University of Minnesota TMC, University of Pittsburgh TMC, University of Washington TDA, Washington University TMC, Yale TMC, SenNet Consortium, Writing Group, Brown University TDA, Buck Institute for Research on Aging TMC/TDA, Consortium Organization and Data Coordinating Center (CODCC), Columbia TMC, Duke University TMC, Massachusetts General Hospital TDA, Mayo Clinic TDA & National Institute of Health (NIH), Dec 2022, In: Nature Aging. 2, 12, p. 1090-1100 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

37 Scopus citations

Nine out of ten samples were mistakenly switched by The Orang-utan Genome Consortium

Banes, G. L., Fountain, E. D., Karklus, A., Fulton, R. S., Antonacci-Fulton, L. & Nelson, J. O., Dec 2022, In: Scientific data. 9, 1, 485.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Personalized ctDNA micro-panels can monitor and predict clinical outcomes for patients with triple-negative breast cancer

Barnell, E. K., Fisk, B., Skidmore, Z. L., Cotto, K. C., Basu, A., Anand, A., Richters, M. M., Luo, J., Fronick, C., Anurag, M., Fulton, R., Ellis, M. J., Griffith, O. L., Griffith, M. & Ademuyiwa, F. O., Dec 2022, In: Scientific reports. 12, 1, 17732.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Recurrent switch 2 domain RAC2 mutations in intravascular large B-cell lymphoma

Kodgule, R., Chen, J., Khonde, P., Robinson, J., D’Albora, A., Cook, L., Fronick, C. C., Fulton, R., Srivatsan, S. N., Cimino, P. J. & Duncavage, E. J., Dec 13 2022, In: Blood Advances. 6, 23, p. 6051-6055 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Semi-automated assembly of high-quality diploid human reference genomes

Human Pangenome Reference Consortium, Cody, S., Fulton, R. S., Fulton, L. L., Li, D., Lindsay, T., Regier, A., Stitziel, N. O., Wang, T. & Hall, I., Nov 17 2022, In: Nature. 611, 7936, p. 519-531 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

70 Scopus citations

Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer

Cui Zhou, D., Jayasinghe, R. G., Chen, S., Herndon, J. M., Iglesia, M. D., Navale, P., Wendl, M. C., Caravan, W., Sato, K., Storrs, E., Mo, C. K., Liu, J., Southard-Smith, A. N., Wu, Y., Naser Al Deen, N., Baer, J. M., Fulton, R. S., Wyczalkowski, M. A., Liu, R. & Fronick, C. C. & 46 others, Fulton, L. A., Shinkle, A., Thammavong, L., Zhu, H., Sun, H., Wang, L. B., Li, Y., Zuo, C., McMichael, J. F., Davies, S. R., Appelbaum, E. L., Robbins, K. J., Chasnoff, S. E., Yang, X., Reeb, A. N., Oh, C., Serasanambati, M., Lal, P., Varghese, R., Mashl, J. R., Ponce, J., Terekhanova, N. V., Yao, L., Wang, F., Chen, L., Schnaubelt, M., Lu, R. J. H., Schwarz, J. K., Puram, S. V., Kim, A. H., Song, S. K., Shoghi, K. I., Lau, K. S., Ju, T., Chen, K., Chatterjee, D., Hawkins, W. G., Zhang, H., Achilefu, S., Chheda, M. G., Oh, S. T., Gillanders, W. E., Chen, F., DeNardo, D. G., Fields, R. C. & Ding, L., Sep 2022, In: Nature Genetics. 54, 9, p. 1390-1405 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

85 Scopus citations

The complete sequence of a human genome

Nurk, S., Koren, S., Rhie, A., Rautiainen, M., Bzikadze, A. V., Mikheenko, A., Vollger, M. R., Altemose, N., Uralsky, L., Gershman, A., Aganezov, S., Hoyt, S. J., Diekhans, M., Logsdon, G. A., Alonge, M., Antonarakis, S. E., Borchers, M., Bouffard, G. G., Brooks, S. Y. & Caldas, G. V. & 80 others, Chen, N. C., Cheng, H., Chin, C. S., Chow, W., de Lima, L. G., Dishuck, P. C., Durbin, R., Dvorkina, T., Fiddes, I. T., Formenti, G., Fulton, R. S., Fungtammasan, A., Garrison, E., Grady, P. G. S., Graves-Lindsay, T. A., Hall, I. M., Hansen, N. F., Hartley, G. A., Haukness, M., Howe, K., Hunkapiller, M. W., Jain, C., Jain, M., Jarvis, E. D., Kerpedjiev, P., Kirsche, M., Kolmogorov, M., Korlach, J., Kremitzki, M., Li, H., Maduro, V. V., Marschall, T., McCartney, A. M., McDaniel, J., Miller, D. E., Mullikin, J. C., Myers, E. W., Olson, N. D., Paten, B., Peluso, P., Pevzner, P. A., Porubsky, D., Potapova, T., Rogaev, E. I., Rosenfeld, J. A., Salzberg, S. L., Schneider, V. A., Sedlazeck, F. J., Shafin, K., Shew, C. J., Shumate, A., Sims, Y., Smit, A. F. A., Soto, D. C., Sovi, I., Storer, J. M., Streets, A., Sullivan, B. A., Thibaud-Nissen, F., Torrance, J., Wagner, J., Walenz, B. P., Wenger, A., Wood, J. M. D., Xiao, C., Yan, S. M., Young, A. C., Zarate, S., Surti, U., McCoy, R. C., Dennis, M. Y., Alexandrov, I. A., Gerton, J. L., O'Neill, R. J., Timp, W., Zook, J. M., Schatz, M. C., Eichler, E. E., Miga, K. H. & Phillippy, A. M., Apr 1 2022, In: Science. 376, 6588, p. 44-53 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1136 Scopus citations

2021

A domestic cat whole exome sequencing resource for trait discovery

Rodney, A. R., Buckley, R. M., Fulton, R. S., Fronick, C., Richmond, T., Helps, C. R., Pantke, P., Trent, D. J., Vernau, K. M., Munday, J. S., Lewin, A. C., Middleton, R., Lyons, L. A. & Warren, W. C., Dec 2021, In: Scientific reports. 11, 1, 7159.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Co-evolution of tumor and immune cells during progression of multiple myeloma

Liu, R., Gao, Q., Foltz, S. M., Fowles, J. S., Yao, L., Wang, J. T., Cao, S., Sun, H., Wendl, M. C., Sethuraman, S., Weerasinghe, A., Rettig, M. P., Storrs, E. P., Yoon, C. J., Wyczalkowski, M. A., McMichael, J. F., Kohnen, D. R., King, J., Goldsmith, S. R. & O’Neal, J. & 9 others, Fulton, R. S., Fronick, C. C., Ley, T. J., Jayasinghe, R. G., Fiala, M. A., Oh, S. T., DiPersio, J. F., Vij, R. & Ding, L., Dec 1 2021, In: Nature communications. 12, 1, 2559.

Research output: Contribution to journal › Article › peer-review

Open Access

75 Scopus citations

Genome sequencing as an alternative to cytogenetic analysis in myeloid cancers

Duncavage, E. J., Schroeder, M. C., O'Laughlin, M., Wilson, R., MacMillan, S., Bohannon, A., Kruchowski, S., Garza, J., Du, F., Hughes, A. E. O., Robinson, J., Hughes, E., Heath, S. E., Baty, J. D., Neidich, J., Christopher, M. J., Jacoby, M. A., Uy, G. L., Fulton, R. S. & Miller, C. A. & 7 others, Payton, J. E., Link, D. C., Walter, M. J., Westervelt, P., DiPersio, J. F., Ley, T. J. & Spencer, D. H., Mar 11 2021, In: New England Journal of Medicine. 384, 10, p. 924-935 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

168 Scopus citations

Genomic Profiling of Lung Adenocarcinoma in Never-Smokers

Devarakonda, S., Li, Y., Martins Rodrigues, F., Sankararaman, S., Kadara, H., Goparaju, C., Lanc, I., Pepin, K., Waqar, S. N., Morgensztern, D., Ward, J., Masood, A., Fulton, R., Fulton, L., Gillette, M. A., Satpathy, S., Carr, S. A., Wistuba, I., Pass, H. & Wilson, R. K. & 2 others, Ding, L. & Govindan, R., Nov 20 2021, In: Journal of Clinical Oncology. 39, 33, p. 3747-3758 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

48 Scopus citations

Immunosuppression and outcomes in adult patients with de novo acute myeloid leukemia with normal karyotypes

Ferraro, F., Miller, C. A., Christensen, K. A., Helton, N. M., O’Laughlin, M., Fronick, C. C., Fulton, R. S., Kohlschmidt, J., Eisfeld, A. K., Bloomfield, C. D., Ramakrishnan, S. M., Day, R. B., Wartman, L., Uy, G. L., Welch, J., Christopher, M. J., Heath, S. E., Baty, J. D., Schuelke, M. J. & Payton, J. E. & 7 others, Spencer, D. H., Rettig, M. P., Link, D. C., Walter, M. J., Westervelt, P., DiPersio, J. F. & Ley, T. J., Dec 7 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 49, e2116427118.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Rapid and Extraction-Free Detection of SARS-CoV-2 from Saliva by Colorimetric Reverse-Transcription Loop-Mediated Isothermal Amplification

Lalli, M. A., Langmade, J. S., Chen, X., Fronick, C. C., Sawyer, C. S., Burcea, L. C., Wilkinson, M. N., Fulton, R. S., Heinz, M., Buchser, W. J., Head, R. D., Mitra, R. D. & Milbrandt, J., Feb 1 2021, In: Clinical chemistry. 67, 2, p. 415-424 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

161 Scopus citations

2020

A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns

PCAWG Tumor Subtypes and Clinical Translation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 728.

Research output: Contribution to journal › Article › peer-review

Open Access

127 Scopus citations

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

PCAWG Consortium, PCAWG Drivers and Functional Interpretation Working Group & PCAWG-Structural Variation Working Group, Feb 6 2020, In: Nature. 578, 7793, p. 102-111 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

361 Scopus citations

Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

PCAWG Drivers and Functional Interpretation Group & PCAWG Consortium, Dec 1 2020, In: Communications Biology. 3, 1, 56.

Research output: Contribution to journal › Article › peer-review

Open Access

145 Scopus citations

Combined burden and functional impact tests for cancer driver discovery using DriverPower

PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 734.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

PCAWG-Structural Variation Working Group & PCAWG Consortium, Mar 1 2020, In: Nature Genetics. 52, 3, p. 331-341 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

392 Scopus citations

Comprehensive molecular characterization of mitochondrial genomes in human cancers

PCAWG Consortium, Mar 1 2020, In: Nature Genetics. 52, 3, p. 342-352 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

234 Scopus citations

Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer

PCAWG-Structural Variation Working Group & PCAWG Consortium, Mar 1 2020, In: Nature Genetics. 52, 3, p. 294-305 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

154 Scopus citations

Divergent mutational processes distinguish hypoxic and normoxic tumours

PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 737.

Research output: Contribution to journal › Article › peer-review

Open Access

84 Scopus citations

Genomic basis for RNA alterations in cancer

PCAWG Transcriptome Core Group, PCAWG Transcriptome Working Group & PCAWG Consortium, Feb 6 2020, In: Nature. 578, 7793, p. 129-136 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

261 Scopus citations

Genomic footprints of activated telomere maintenance mechanisms in cancer

PCAWG-Structural Variation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 733.

Research output: Contribution to journal › Article › peer-review

Open Access

75 Scopus citations

Harnessing Expressed Single Nucleotide Variation and Single Cell RNA Sequencing to Define Immune Cell Chimerism in the Rejecting Kidney Transplant

Malone, A. F., Wu, H., Fronick, C., Fulton, R., Gaut, J. P. & Humphreys, B. D., Sep 2020, In: Journal of the American Society of Nephrology. 31, 9, p. 1977-1986 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

71 Scopus citations

High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations

PCAWG Transcriptome Working Group, PCAWG-Structural Variation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 736.

Research output: Contribution to journal › Article › peer-review

Open Access

49 Scopus citations

Inferring structural variant cancer cell fraction

PCAWG Consortium & PCAWG Evolution and Heterogeneity Working Group, Dec 1 2020, In: Nature communications. 11, 1, 730.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Integrative pathway enrichment analysis of multivariate omics data

PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 735.

Research output: Contribution to journal › Article › peer-review

Open Access

112 Scopus citations

Mapping and characterization of structural variation in 17,795 human genomes

NHGRI Centers for Common Disease Genomics, Jul 2 2020, In: Nature. 583, 7814, p. 83-89 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

148 Scopus citations

Pan-cancer analysis of whole genomes

The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, Feb 6 2020, In: Nature. 578, 7793, p. 82-93 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1699 Scopus citations

Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

PCAWG-Structural Variation Working Group & PCAWG Consortium, Mar 1 2020, In: Nature Genetics. 52, 3, p. 306-319 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

241 Scopus citations

Pathway and network analysis of more than 2500 whole cancer genomes

PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 729.

Research output: Contribution to journal › Article › peer-review

Open Access

68 Scopus citations

Precise breakpoint detection in a patient with 9p– syndrome

Ng, J., Sams, E., Baldridge, D., Kremitzki, M., Wegner, D. J., Lindsay, T., Fulton, R., Cole, F. S. & Turner, T. N., Feb 2020, In: Cold Spring Harbor molecular case studies. 6, 3, a005348.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig

PCAWG Evolution and Heterogeneity Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 731.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Remethylation of Dnmt3a^−/− hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing

Ketkar, S., Verdoni, A. M., Smith, A. M., Bangert, C. V., Leight, E. R., Chen, D. Y., Brune, M. K., Helton, N. M., Hoock, M., George, D. R., Fronick, C., Fulton, R. S., Ramakrishnan, S. M., Chang, G. S., Petti, A. A., Spencer, D. H., Miller, C. A. & Ley, T. J., Feb 11 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 6, p. 3123-3134 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

Robert Fulton

Research output

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