Robert Fulton

Research output

Research output per year 1994 2014 2018 2022

• 240 Article
• 17 Comment/debate
• 4 Letter
• 3 Review article
• 2 More
  • 1 Chapter
  • 1 Short survey

Research output per year

Research output per year

Search results

• 2022

  Author Correction: Comparative and demographic analysis of orang-utan genomes (Nature, (2011), 469, 7331, (529-533), 10.1038/nature09687)

  Locke, D. P., Hillier, L. D. W., Warren, W. C., Worley, K. C., Nazareth, L. V., Muzny, D. M., Yang, S. P., Wang, Z., Chinwalla, A. T., Minx, P., Mitreva, M., Cook, L., Delehaunty, K. D., Fronick, C., Schmidt, H., Fulton, L. A., Fulton, R. S., Nelson, J. O., Magrini, V., Pohl, C., & 81 othersGraves, T. A., Markovic, C., Cree, A., Dinh, H. H., Hume, J., Kovar, C. L., Fowler, G. R., Lunter, G., Meader, S., Heger, A., Ponting, C. P., Marques-Bonet, T., Alkan, C., Chen, L., Cheng, Z., Kidd, J. M., Eichler, E. E., White, S., Searle, S., Vilella, A. J., Chen, Y., Flicek, P., Ma, J., Raney, B., Suh, B., Burhans, R., Herrero, J., Haussler, D., Faria, R., Fernando, O., Darré, F., Farré, D., Gazave, E., Oliva, M., Navarro, A., Roberto, R., Capozzi, O., Archidiacono, N., Della Valle, G., Purgato, S., Rocchi, M., Konkel, M. K., Walker, J. A., Ullmer, B., Batzer, M. A., Smit, A. F. A., Hubley, R., Casola, C., Schrider, D. R., Hahn, M. W., Quesada, V., Puente, X. S., Ordoñez, G. R., López-Otín, C., Vinar, T., Brejova, B., Ratan, A., Harris, R. S., Miller, W., Kosiol, C., Lawson, H. A., Taliwal, V., Martins, A. L., Siepel, A., RoyChoudhury, A., Ma, X., Degenhardt, J., Bustamante, C. D., Gutenkunst, R. N., Mailund, T., Dutheil, J. Y., Hobolth, A., Schierup, M. H., Ryder, O. A., Yoshinaga, Y., de Jong, P. J., Weinstock, G. M., Rogers, J., Mardis, E. R., Gibbs, R. A. & Wilson, R. K., Aug 25 2022, In: Nature. 608, 7924, p. E36

  Research output: Contribution to journal › Comment/debate

  Open Access

  • Genome 100%
  • Demography 95%
  • Single Nucleotide Polymorphism 82%
  • Publications 81%
  • Names 46%

• Author Correction: A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing (Nature Communications, (2019), 10, 1, (3660), 10.1038/s41467-019-11591-1)

  Petti, A. A., Williams, S. R., Miller, C., Fiddes, I. T., Srivatsan, S. N., Chen, D., Fronick, C. C., Fulton, R., Church, D. M. & Ley, T. J., Dec 2022, In: Nature communications. 13, 1, 4216.

  Research output: Contribution to journal › Comment/debate

  Open Access

  • Small Cytoplasmic RNA 100%
  • RNA Sequencing 92%
  • sequencing 76%
  • mutations 65%
  • RNA Sequence Analysis 62%

• Failure to Detect Mutations in U2AF1 due to Changes in the GRCh38 Reference Sequence

  Miller, C. A., Walker, J. R., Jensen, T. L., Hooper, W. F., Fulton, R. S., Painter, J. S., Sekeres, M. A., Ley, T. J., Spencer, D. H., Goll, J. B. & Walter, M. J., Mar 2022, In: Journal of Molecular Diagnostics. 24, 3, p. 219-223 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • GATA2 Deficiency 100%
  • Mutation 80%
  • Genes 57%
  • Carcinogenesis 55%
  • Messenger RNA 41%
  1 Scopus citations

• Focal disruption of DNA methylation dynamics at enhancers in IDH-mutant AML cells

  Wilson, E. R., Helton, N. M., Heath, S. E., Fulton, R., Payton, J. E., Welch, J., Walter, M., Westervelt, P., DiPersio, J. F., Link, D. C., Miller, C., Ley, T. J. & Spencer, D., Apr 2022, In: Leukemia. 36, 4, p. 935-945 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Myeloid Cells 100%
  • DNA Methylation 96%
  • Acute Myeloid Leukemia 93%
  • DNA Demethylation 39%
  • Mutation 31%
  3 Scopus citations

• Genomic and transcriptomic somatic alterations of hepatocellular carcinoma in non-cirrhotic livers

  Skidmore, Z. L., Kunisaki, J., Lin, Y., Cotto, K. C., Barnell, E. K., Hundal, J., Krysiak, K., Magrini, V., Trani, L., Walker, J. R., Fulton, R., Brunt, E. M., Miller, C. A., Wilson, R. K., Mardis, E. R., Griffith, M., Chapman, W. & Griffith, O. L., Jun 2022, In: Cancer Genetics. 264-265, p. 90-99 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• IL-1β expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC function

  Li, S., Yao, J. C., Oetjen, K. A., Krambs, J. R., Xia, J., Zhang, J., Schmidt, A. P., Helton, N. M., Fulton, R. S., Heath, S. E., Turnbull, I. R., Mbalaviele, G., Ley, T. J., Walter, M. J. & Link, D. C., Oct 6 2022, In: Blood. 140, 14, p. 1607-1620 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Toll-Like Receptor 1 100%
  • Interleukin-1 75%
  • Hematopoietic Stem Cells 74%
  • Agonist 72%
  • Bone Marrow Cells 71%
  1 Scopus citations

• Nine out of ten samples were mistakenly switched by The Orang-utan Genome Consortium

  Banes, G. L., Fountain, E. D., Karklus, A., Fulton, R., Antonacci-Fulton, L. & Nelson, J. O., Dec 2022, In: Scientific data. 9, 1, 485.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Genome 100%
  • Consortium 97%
  • Genomics 94%
  • Comparative Genomics 28%
  • Sequencing 25%

• Personalized ctDNA micro-panels can monitor and predict clinical outcomes for patients with triple-negative breast cancer

  Barnell, E. K., Fisk, B., Skidmore, Z. L., Cotto, K. C., Basu, A., Anand, A., Richters, M. M., Luo, J., Fronick, C., Anurag, M., Fulton, R., Ellis, M. J., Griffith, O. L., Griffith, M. & Ademuyiwa, F. O., Dec 2022, In: Scientific reports. 12, 1, 17732.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Circulating Tumor DNA 100%
  • Triple Negative Breast Neoplasms 83%
  • Recurrence 39%
  • Alleles 9%
  • Whole Exome Sequencing 7%

• Recurrent switch 2 domain RAC2 mutations in intravascular large B-cell lymphoma

  Kodgule, R., Chen, J., Khonde, P., Robinson, J., D’Albora, A., Cook, L., Fronick, C. C., Fulton, R., Srivatsan, S. N., Cimino, P. J. & Duncavage, E. J., Dec 13 2022, In: Blood Advances. 6, 23, p. 6051-6055 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Scopus citations

• Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer

  Cui Zhou, D., Jayasinghe, R. G., Chen, S., Herndon, J. M., Iglesia, M. D., Navale, P., Wendl, M. C., Caravan, W., Sato, K., Storrs, E., Mo, C. K., Liu, J., Southard-Smith, A. N., Wu, Y., Naser Al Deen, N., Baer, J. M., Fulton, R. S., Wyczalkowski, M. A., Liu, R., Fronick, C. C., & 46 othersFulton, L. A., Shinkle, A., Thammavong, L., Zhu, H., Sun, H., Wang, L. B., Li, Y., Zuo, C., McMichael, J. F., Davies, S. R., Appelbaum, E. L., Robbins, K. J., Chasnoff, S. E., Yang, X., Reeb, A. N., Oh, C., Serasanambati, M., Lal, P., Varghese, R., Mashl, J. R., Ponce, J., Terekhanova, N. V., Yao, L., Wang, F., Chen, L., Schnaubelt, M., Lu, R. J. H., Schwarz, J. K., Puram, S. V., Kim, A. H., Song, S. K., Shoghi, K. I., Lau, K. S., Ju, T., Chen, K., Chatterjee, D., Hawkins, W. G., Zhang, H., Achilefu, S., Chheda, M. G., Oh, S. T., Gillanders, W. E., Chen, F., DeNardo, D. G., Fields, R. C. & Ding, L., Sep 2022, In: Nature Genetics. 54, 9, p. 1390-1405 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pancreatic Neoplasms 100%
  • Population 41%
  • Neoplasms 34%
  • Proteogenomics 29%
  • Adenocarcinoma 27%
  5 Scopus citations

• The complete sequence of a human genome

  Nurk, S., Koren, S., Rhie, A., Rautiainen, M., Bzikadze, A. V., Mikheenko, A., Vollger, M. R., Altemose, N., Uralsky, L., Gershman, A., Aganezov, S., Hoyt, S. J., Diekhans, M., Logsdon, G. A., Alonge, M., Antonarakis, S. E., Borchers, M., Bouffard, G. G., Brooks, S. Y., Caldas, G. V., & 80 othersChen, N. C., Cheng, H., Chin, C. S., Chow, W., de Lima, L. G., Dishuck, P. C., Durbin, R., Dvorkina, T., Fiddes, I. T., Formenti, G., Fulton, R. S., Fungtammasan, A., Garrison, E., Grady, P. G. S., Graves-Lindsay, T. A., Hall, I. M., Hansen, N. F., Hartley, G. A., Haukness, M., Howe, K., Hunkapiller, M. W., Jain, C., Jain, M., Jarvis, E. D., Kerpedjiev, P., Kirsche, M., Kolmogorov, M., Korlach, J., Kremitzki, M., Li, H., Maduro, V. V., Marschall, T., McCartney, A. M., McDaniel, J., Miller, D. E., Mullikin, J. C., Myers, E. W., Olson, N. D., Paten, B., Peluso, P., Pevzner, P. A., Porubsky, D., Potapova, T., Rogaev, E. I., Rosenfeld, J. A., Salzberg, S. L., Schneider, V. A., Sedlazeck, F. J., Shafin, K., Shew, C. J., Shumate, A., Sims, Y., Smit, A. F. A., Soto, D. C., Sovi, I., Storer, J. M., Streets, A., Sullivan, B. A., Thibaud-Nissen, F., Torrance, J., Wagner, J., Walenz, B. P., Wenger, A., Wood, J. M. D., Xiao, C., Yan, S. M., Young, A. C., Zarate, S., Surti, U., McCoy, R. C., Dennis, M. Y., Alexandrov, I. A., Gerton, J. L., O'Neill, R. J., Timp, W., Zook, J. M., Schatz, M. C., Eichler, E. E., Miga, K. H. & Phillippy, A. M., Apr 1 2022, In: Science. 376, 6588, p. 44-53 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Human Genome 100%
  • Telomere 69%
  • Base Pairing 65%
  • Genome 64%
  • Genomic Segmental Duplications 48%
  225 Scopus citations

• The Human Pangenome Project: a global resource to map genomic diversity

  Human Pangenome Reference Consortium, Apr 1 2022, In: Nature. 604, 7906, p. 437-446 10 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Telomere 100%
  • Human Genome 95%
  • Genome 61%
  • Human Genetics 55%
  • Nucleic Acid Repetitive Sequences 55%
  24 Scopus citations
• 2021

  A domestic cat whole exome sequencing resource for trait discovery

  Rodney, A. R., Buckley, R. M., Fulton, R. S., Fronick, C., Richmond, T., Helps, C. R., Pantke, P., Trent, D. J., Vernau, K. M., Munday, J. S., Lewin, A. C., Middleton, R., Lyons, L. A. & Warren, W. C., Dec 2021, In: Scientific reports. 11, 1, 7159.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Whole Exome Sequencing 100%
  • Cats 71%
  • Genome 32%
  • Exome 28%
  • Nucleotides 19%
  6 Scopus citations

• Co-evolution of tumor and immune cells during progression of multiple myeloma

  Liu, R., Gao, Q., Foltz, S. M., Fowles, J. S., Yao, L., Wang, J. T., Cao, S., Sun, H., Wendl, M. C., Sethuraman, S., Weerasinghe, A., Rettig, M. P., Storrs, E. P., Yoon, C. J., Wyczalkowski, M. A., McMichael, J. F., Kohnen, D. R., King, J., Goldsmith, S. R., O’Neal, J., & 9 othersFulton, R. S., Fronick, C. C., Ley, T. J., Jayasinghe, R. G., Fiala, M. A., Oh, S. T., DiPersio, J. F., Vij, R. & Ding, L., Dec 1 2021, In: Nature communications. 12, 1, 2559.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • progressions 100%
  • Plasma Cells 89%
  • Multiple Myeloma 88%
  • tumors 85%
  • Plasma 54%
  25 Scopus citations

• Genome sequencing as an alternative to cytogenetic analysis in myeloid cancers

  Duncavage, E. J., Schroeder, M. C., O'Laughlin, M., Wilson, R., MacMillan, S., Bohannon, A., Kruchowski, S., Garza, J., Du, F., Hughes, A. E. O., Robinson, J., Hughes, E., Heath, S. E., Baty, J. D., Neidich, J., Christopher, M. J., Jacoby, M. A., Uy, G. L., Fulton, R. S., Miller, C. A., & 7 othersPayton, J. E., Link, D. C., Walter, M. J., Westervelt, P., DiPersio, J. F., Ley, T. J. & Spencer, D. H., Mar 11 2021, In: New England Journal of Medicine. 384, 10, p. 924-935 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cytogenetic Analysis 100%
  • Whole Genome Sequencing 66%
  • Genome 58%
  • Neoplasms 27%
  • GATA2 Deficiency 26%
  72 Scopus citations

• Genomic Profiling of Lung Adenocarcinoma in Never-Smokers

  Devarakonda, S., Li, Y., Martins Rodrigues, F., Sankararaman, S., Kadara, H., Goparaju, C., Lanc, I., Pepin, K., Waqar, S. N., Morgensztern, D., Ward, J., Masood, A., Fulton, R., Fulton, L., Gillette, M. A., Satpathy, S., Carr, S. A., Wistuba, I., Pass, H., Wilson, R. K., & 2 othersDing, L. & Govindan, R., Nov 20 2021, In: Journal of Clinical Oncology. 39, 33, p. 3747-3758 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Adenocarcinoma of Lung 100%
  • Smokers 79%
  • RNA Sequence Analysis 19%
  • Whole Exome Sequencing 13%
  • Smoke 11%
  10 Scopus citations

• Immunosuppression and outcomes in adult patients with de novo acute myeloid leukemia with normal karyotypes

  Ferraro, F., Miller, C. A., Christensen, K. A., Helton, N. M., O’Laughlin, M., Fronick, C. C., Fulton, R. S., Kohlschmidt, J., Eisfeld, A. K., Bloomfield, C. D., Ramakrishnan, S. M., Day, R. B., Wartman, L., Uy, G. L., Welch, J., Christopher, M. J., Heath, S. E., Baty, J. D., Schuelke, M. J., Payton, J. E., & 7 othersSpencer, D. H., Rettig, M. P., Link, D. C., Walter, M. J., Westervelt, P., DiPersio, J. F. & Ley, T. J., Dec 7 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 49, e2116427118.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Karyotype 100%
  • Acute Myeloid Leukemia 93%
  • Immunosuppression 88%
  • Myeloid Cells 36%
  • Drug Therapy 20%
  2 Scopus citations

• Rapid and Extraction-Free Detection of SARS-CoV-2 from Saliva by Colorimetric Reverse-Transcription Loop-Mediated Isothermal Amplification

  Lalli, M. A., Langmade, J. S., Chen, X., Fronick, C. C., Sawyer, C. S., Burcea, L. C., Wilkinson, M. N., Fulton, R. S., Heinz, M., Buchser, W. J., Head, R. D., Mitra, R. D. & Milbrandt, J., Feb 1 2021, In: Clinical chemistry. 67, 2, p. 415-424 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SARS Virus 100%
  • Saliva 66%
  • Reverse Transcription 59%
  • RNA 14%
  • Polymerase Chain Reaction 12%
  112 Scopus citations
• 2020

  Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (Nature Communications, (2020), 11, 1, (4748), 10.1038/s41467-020-18151-y)

  MC3 Working Group, PCAWG novel somatic mutation calling methods working group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 6232.

  Research output: Contribution to journal › Comment/debate

  Open Access

  • genome 100%
  • Exome 92%
  • mutations 89%
  • medicine 82%
  • cancer 71%

• Harnessing Expressed Single Nucleotide Variation and Single Cell RNA Sequencing to Define Immune Cell Chimerism in the Rejecting Kidney Transplant

  Malone, A. F., Wu, H., Fronick, C., Fulton, R., Gaut, J. P. & Humphreys, B. D., Sep 2020, In: Journal of the American Society of Nephrology. 31, 9, p. 1977-1986 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Chimerism 100%
  • RNA Sequence Analysis 89%
  • Nucleotides 64%
  • Tissue Donors 62%
  • Transplants 49%
  32 Scopus citations

• Mapping and characterization of structural variation in 17,795 human genomes

  NHGRI Centers for Common Disease Genomics, Jul 2 2020, In: Nature. 583, 7814, p. 83-89 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Whole Genome Sequencing 100%
  • Human Genome 90%
  • Alleles 62%
  • Genome 38%
  • Human Genetics 35%
  80 Scopus citations

• Pan-cancer analysis of whole genomes

  The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, Feb 6 2020, In: Nature. 578, 7793, p. 82-93 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Genome 100%
  • Neoplasms 47%
  • Mutation 21%
  • Telomere 21%
  • Point Mutation 19%
  1038 Scopus citations

• Precise breakpoint detection in a patient with 9p– syndrome

  Ng, J., Sams, E., Baldridge, D., Kremitzki, M., Wegner, D. J., Lindsay, T., Fulton, R., Cole, F. S. & Turner, T. N., Feb 2020, In: Cold Spring Harbor molecular case studies. 6, 3, a005348.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Developmental 100%
  • Genomics 83%
  • Karyotype 42%
  • Technology 40%
  • Chromosome Duplication 30%
  3 Scopus citations

• Remethylation of Dnmt3a^−/− hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing

  Ketkar, S., Verdoni, A. M., Smith, A. M., Bangert, C. V., Leight, E. R., Chen, D. Y., Brune, M. K., Helton, N. M., Hoock, M., George, D. R., Fronick, C., Fulton, R. S., Ramakrishnan, S. M., Chang, G. S., Petti, A. A., Spencer, D. H., Miller, C. A. & Ley, T. J., Feb 11 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 6, p. 3123-3134 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • DNA methyltransferase 3A 100%
  • Acute Myeloid Leukemia 28%
  • Genes 24%
  • Mutation 22%
  • Hematopoiesis 21%
  13 Scopus citations

• Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

  MC3 Working Group, PCAWG novel somatic mutation calling methods working group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 4748.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • genome 100%
  • Exome 92%
  • mutations 89%
  • sequencing 87%
  • cancer 71%
  18 Scopus citations

• Sex differences in oncogenic mutational processes

  PCAWG Tumour Subtypes and Clinical Translation & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 4330.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oncogenic 100%
  • Sex Characteristics 66%
  • Mutation 60%
  • cancer 57%
  • genome 39%
  33 Scopus citations

• Telomere-to-telomere assembly of a complete human X chromosome

  Miga, K. H., Koren, S., Rhie, A., Vollger, M. R., Gershman, A., Bzikadze, A., Brooks, S., Howe, E., Porubsky, D., Logsdon, G. A., Schneider, V. A., Potapova, T., Wood, J., Chow, W., Armstrong, J., Fredrickson, J., Pak, E., Tigyi, K., Kremitzki, M., Markovic, C., & 33 othersMaduro, V., Dutra, A., Bouffard, G. G., Chang, A. M., Hansen, N. F., Wilfert, A. B., Thibaud-Nissen, F., Schmitt, A. D., Belton, J. M., Selvaraj, S., Dennis, M. Y., Soto, D. C., Sahasrabudhe, R., Kaya, G., Quick, J., Loman, N. J., Holmes, N., Loose, M., Surti, U., Risques, R. A., Graves Lindsay, T. A., Fulton, R., Hall, I., Paten, B., Howe, K., Timp, W., Young, A., Mullikin, J. C., Pevzner, P. A., Gerton, J. L., Sullivan, B. A., Eichler, E. E. & Phillippy, A. M., Sep 3 2020, In: Nature. 585, 7823, p. 79-84 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Chromosomes, Human, X 100%
  • Telomere 71%
  • Human Genome 67%
  • Human Chromosomes 36%
  • Nanopore Sequencing 27%
  276 Scopus citations

• The clonal evolution of metastatic colorectal cancer

  Dang, H. X., Krasnick, B. A., White, B. S., Grossman, J. G., Strand, M. S., Zhang, J., Cabanski, C. R., Miller, C. A., Fulton, R. S., Goedegebuure, S. P., Fronick, C. C., Griffith, M., Larson, D. E., Goetz, B. D., Walker, J. R., Hawkins, W. G., Strasberg, S. M., Linehan, D. C., Lim, K. H., Lockhart, A. C., & 5 othersMardis, E. R., Wilson, R. K., Ley, T. J., Maher, C. A. & Fields, R. C., Jun 2020, In: Science Advances. 6, 24, eaay9691.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Clonal Evolution 100%
  • Colorectal Neoplasms 57%
  • Heterografts 56%
  • Neoplasm Metastasis 38%
  • Neoplasms 14%
  19 Scopus citations

• The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution

  Human Tumor Atlas Network, Apr 16 2020, In: Cell. 181, 2, p. 236-249 14 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Ecosystem 100%
  • Atlases 90%
  • Biological Marker 75%
  • Time 30%
  • Neoplasms 27%
  163 Scopus citations
• 2019

  A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing

  Petti, A. A., Williams, S. R., Miller, C. A., Fiddes, I. T., Srivatsan, S. N., Chen, D. Y., Fronick, C. C., Fulton, R. S., Church, D. M. & Ley, T. J., Dec 1 2019, In: Nature communications. 10, 1, 3660.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • RNA Sequencing 100%
  • leukemias 87%
  • sequencing 81%
  • mutations 70%
  • RNA Sequence Analysis 67%
  74 Scopus citations

• A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease

  Alzheimer's Disease Sequencing Project, Mar 2019, In: Alzheimer's and Dementia. 15, 3, p. 441-452 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Alzheimer disease type 2 100%
  • dementia 66%
  • Alzheimer Disease 51%
  • Datasets 39%
  • Hispanic Americans 31%
  23 Scopus citations

• Author Correction: Exome sequencing of Finnish isolates enhances rare-variant association power (Nature, (2019), 572, 7769, (323-328), 10.1038/s41586-019-1457-z)

  FinnGen Project, Nov 21 2019, In: Nature. 575, 7783, p. E4

  Research output: Contribution to journal › Comment/debate

  Open Access

  • Exome 100%
  3 Scopus citations

• Erratum: The Immune Landscape of Cancer (Immunity (2018) 48(4) (812–830.e14), (S1074761318301213), (10.1016/j.immuni.2018.03.023))

  The Cancer Genome Atlas Research Network, Aug 20 2019, In: Immunity. 51, 2, p. 411-412 2 p.

  Research output: Contribution to journal › Comment/debate

  Open Access

  • Immunity 100%
  • Names 77%
  • Genes 49%
  • Neoplasms 39%
  • Research Design 32%
  135 Scopus citations

• Exome sequencing of Finnish isolates enhances rare-variant association power

  FinnGen Project, Aug 15 2019, In: Nature. 572, 7769, p. 323-328 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Exome 100%
  • Alleles 61%
  • Multifactorial Inheritance 20%
  • Population Characteristics 19%
  • Population 19%
  77 Scopus citations

• No evidence that G6PD deficiency affects the efficacy or safety of daunorubicin in acute lymphoblastic leukemia induction therapy

  Robinson, K. M., Yang, W., Karol, S. E., Kornegay, N., Jay, D., Cheng, C., Choi, J. K., Campana, D., Pui, C. H., Wood, B., Borowitz, M. J., Gastier-Foster, J., Larsen, E. C., Winick, N., Carroll, W. L., Loh, M. L., Raetz, E. A., Hunger, S. P., Devidas, M., Mardis, E. R., & 3 othersFulton, R. S., Relling, M. V. & Jeha, S., Jun 2019, In: Pediatric Blood and Cancer. 66, 6, e27681.

  Research output: Contribution to journal › Article › peer-review

  • Glucosephosphate Dehydrogenase Deficiency 100%
  • Daunorubicin 91%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 70%
  • Residual Neoplasm 57%
  • Erythrocyte Transfusion 44%
  3 Scopus citations

• Publisher Correction: Subsets of ILC3−ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues (Nature Immunology, (2019), 20, 8, (980-991), 10.1038/s41590-019-0425-y)

  Cella, M., Gamini, R., Sécca, C., Collins, P. L., Zhao, S., Peng, V., Robinette, M. L., Schettini, J., Zaitsev, K., Gordon, W., Bando, J. K., Yomogida, K., Cortez, V., Fronick, C., Fulton, R., Lin, L. L., Gilfillan, S., Flavell, R. A., Shan, L., Artyomov, M. N., & 4 othersBowman, M., Oltz, E. M., Jelinsky, S. A. & Colonna, M., Oct 1 2019, In: Nature immunology. 20, 10, p. 1405 1 p.

  Research output: Contribution to journal › Comment/debate

  Open Access

  • Allergy and Immunology 100%
  • Mucous Membrane 74%
  • Lymphocytes 64%
  7 Scopus citations

• Subsets of ILC3−ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues

  Cella, M., Gamini, R., Sécca, C., Collins, P. L., Zhao, S., Peng, V., Robinette, M. L., Schettini, J., Zaitsev, K., Gordon, W., Bando, J. K., Yomogida, K., Cortez, V., Fronick, C., Fulton, R., Lin, L. L., Gilfillan, S., Flavell, R. A., Shan, L., Artyomov, M. N., & 4 othersBowman, M., Oltz, E. M., Jelinsky, S. A. & Colonna, M., Aug 1 2019, In: Nature immunology. 20, 8, p. 980-991 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Mucous Membrane 100%
  • Lymphocytes 86%
  • T-box transcription factor TBX21 49%
  • interleukin-22 42%
  • Cytokines 38%
  94 Scopus citations
• 2018

  A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

  The Cancer Genome Atlas Research Network, Apr 9 2018, In: Cancer Cell. 33, 4, p. 690-705.e9

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Atlases 100%
  • Breast Neoplasms 99%
  • Decision Trees 77%
  • Long Noncoding RNA 67%
  • Genome 63%
  296 Scopus citations

• A multiple myeloma-specific capture sequencing platform discovers novel translocations and frequent, risk-associated point mutations in IGLL5

  White, B. S., Lanc, I., O'Neal, J., Gupta, H., Fulton, R. S., Schmidt, H., Fronick, C., Belter, E. A., Fiala, M., King, J., Ahmann, G. J., Derome, M., Mardis, E. R., Vij, R., Dipersio, J. F., Levy, J., Auclair, D. & Tomasson, M. H., Mar 1 2018, In: Blood cancer journal. 8, 3, 35.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Multiple Myeloma 100%
  • Point Mutation 98%
  • Mutation 56%
  • Monosomy 1p Chromosome 1 40%
  • Nucleotides 40%
  27 Scopus citations

• An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

  The Cancer Genome Atlas Research Network, Apr 5 2018, In: Cell. 173, 2, p. 400-416.e11

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Atlases 100%
  • Genome 63%
  • Survival 51%
  • Neoplasms 30%
  • Datasets 9%
  1297 Scopus citations

• An “off-the-shelf” fratricide-resistant CAR-T for the treatment of T cell hematologic malignancies

  Cooper, M. L., Choi, J., Staser, K., Ritchey, J. K., Devenport, J. M., Eckardt, K., Rettig, M. P., Wang, B., Eissenberg, L. G., Ghobadi, A., Gehrs, L. N., Prior, J. L., Achilefu, S., Miller, C. A., Fronick, C. C., O’Neal, J., Gao, F., Weinstock, D. M., Gutierrez, A., Fulton, R. S., & 1 othersDiPersio, J. F., Sep 1 2018, In: Leukemia. 32, 9, p. 1970-1983 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Chimeric Antigen Receptors 100%
  • Hematologic Neoplasms 75%
  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 48%
  • T-Lymphocytes 45%
  • Antigen Receptors, T-Cell, alpha-beta 17%
  197 Scopus citations

• A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples

  The Cancer Genome Atlas Research Network, Apr 5 2018, In: Cell. 173, 2, p. 386-399.e12

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Enhancer 100%
  • Neoplasms 27%
  • Genes 14%
  • RNA-Seq 14%
  • Aneuploidy 12%
  148 Scopus citations

• A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily

  The Cancer Genome Atlas Research Network, Oct 24 2018, In: Cell Systems. 7, 4, p. 422-437.e7

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Transforming Growth Factors 100%
  • Sequence Deletion 31%
  • Neoplasms 30%
  • Genes 21%
  • Transforming Growth Factor-beta Type II Receptors 19%
  92 Scopus citations

• Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

  The Cancer Genome Atlas Network, Apr 5 2018, In: Cell. 173, 2, p. 291-304.e6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • MicroRNA 100%
  • Cluster Analysis 36%
  • Protein 33%
  • Neoplasms 26%
  • Aneuploidy 21%
  1037 Scopus citations

• Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential

  Wong, T. N., Miller, C. A., Jotte, M. R. M., Bagegni, N., Baty, J. D., Schmidt, A. P., Cashen, A. F., Duncavage, E. J., Helton, N. M., Fiala, M., Fulton, R. S., Heath, S. E., Janke, M., Luber, K., Westervelt, P., Vij, R., Dipersio, J. F., Welch, J. S., Graubert, T. A., Walter, M. J., & 2 othersLey, T. J. & Link, D. C., Dec 1 2018, In: Nature communications. 9, 1, 455.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • mutations 100%
  • Mutation 72%
  • Clone Cells 68%
  • expansion 53%
  • transplantation 53%
  97 Scopus citations

• Clinical outcomes and differential effects of PI3K pathway mutation in obese versus non-obese patients with cervical cancer

  Grigsby, P., Elhammali, A., Ruiz, F., Markovina, S., McLellan, M. D., Miller, C. A., Chundury, A., Ta, N. A. L., Rashmi, R., Pfeifer, J. D., Fulton, R. S., DeWees, T. & Schwarz, J. K., 2018, In: Oncotarget. 9, 3, p. 4061-4073 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Phosphatidylinositol 3-Kinases 100%
  • Uterine Cervical Neoplasms 93%
  • Mutation 56%
  • Radiation 16%
  • Body Mass Index 16%
  9 Scopus citations

• Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas

  The Cancer Genome Atlas Research Network, Apr 9 2018, In: Cancer Cell. 33, 4, p. 721-735.e8

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adenocarcinoma 100%
  • Genome 49%
  • Chromosomal Instability 45%
  • Neoplasms 41%
  • Rectum 36%
  268 Scopus citations

• Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

  The Cancer Genome Atlas Research Network, Aug 13 2018, In: Cancer Cell. 34, 2, p. 211-224.e6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Alternative Splicing 100%
  • Neoplasms 29%
  • Exons 12%
  • Peptides 9%
  • Whole Exome Sequencing 9%
  381 Scopus citations

• Comprehensive Characterization of Cancer Driver Genes and Mutations

  The MC3 Working Group & The Cancer Genome Atlas Research Network, Apr 5 2018, In: Cell. 173, 2, p. 371-385.e18

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neoplasm Genes 100%
  • Mutation 77%
  • Neoplasms 29%
  • Oncogenic 25%
  • Catalogs 11%
  941 Scopus citations

• Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer

  The Cancer Genome Atlas Research Network, Oct 30 2018, In: Cell Reports. 25, 5, p. 1304-1317.e5

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • MicroRNA 100%
  • Heterogeneity 75%
  • Mutation 68%
  • Neoplasms 26%
  • Squamous Cell Neoplasms 20%
  188 Scopus citations