Robert Culverhouse

Associate Professor of Medicine, Associate Professor of Biostatistics

  • 3327 Citations

Research output per year

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Personal profile

Research interests

My primary research interest is analytical issues related to complex phenotypes, with a particular interest in how statistical interactions among genes or between genes and environmental factors may mask genetic associations to phenotype. I am a mathematician and statistical geneticist with particular expertise in the genetics of addiction and psychiatric traits. My research encompasses the development, evaluation, and application of statistical methods to identify genes and interaction effects that influence human complex traits, with particular focus on addictions and other psychiatric phenotypes.

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Research Output

Dissecting the genetic overlap of smoking behaviors, lung cancer, and chronic obstructive pulmonary disease: A focus on nicotinic receptors and nicotine metabolizing enzyme

Bray, M. J., Chen, L-S., Fox, L., Hancock, D. B., Culverhouse, R., Hartz, S. M., Johnson, E. O., Liu, M., McKay, J. D., Saccone, N., Hokanson, J. E., Vrieze, S. I., Tyndale, R. F., Baker, T. B. & Bierut, L. J., 2020, (Accepted/In press) In : Genetic Epidemiology.

Research output: Contribution to journalArticle

  • Genetic Variant in CHRNA5 and Response to Varenicline and Combination Nicotine Replacement in a Randomized Placebo-Controlled Trial

    Chen, L-S., Baker, T. B., Miller, J. P., Bray, M., Smock, N., Chen, J., Stoneking, F., Culverhouse, R., Saccone, N., Amos, C. I., Carney, R. M., Jorenby, D. E. & Bierut, L. J., 2020, (Accepted/In press) In : Clinical pharmacology and therapeutics.

    Research output: Contribution to journalArticle

  • 2 Scopus citations
  • 9 Scopus citations

    Collaborative meta-Analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression

    Culverhouse, R. C., Saccone, N. L., Horton, A. C., Ma, Y., Anstey, K. J., Banaschewski, T., Burmeister, M., Cohen-Woods, S., Etain, B., Fisher, H. L., Goldman, N., Guillaume, S., Horwood, J., Juhasz, G., Lester, K. J., Mandelli, L., Middeldorp, C. M., Olié, E., Villafuerte, S., Air, T. M. & 73 others, Araya, R., Bowes, L., Burns, R., Byrne, E. M., Coffey, C., Coventry, W. L., Gawronski, K. A. B., Glei, D., Hatzimanolis, A., Hottenga, J. J., Jaussent, I., Jawahar, C., Jennen-Steinmetz, C., Kramer, J. R., Lajnef, M., Little, K., Zu Schwabedissen, H. M., Nauck, M., Nederhof, E., Petschner, P., Peyrot, W. J., Schwahn, C., Sinnamon, G., Stacey, D., Tian, Y., Toben, C., Van Der Auwera, S., Wainwright, N., Wang, J. C., Willemsen, G., Anderson, I. M., Arolt, V., Aslund, C., Bagdy, G., Baune, B. T., Bellivier, F., Boomsma, D. I., Courtet, P., Dannlowski, U., De Geus, E. J. C., Deakin, J. F. W., Easteal, S., Eley, T., Fergusson, D. M., Goate, A. M., Gonda, X., Grabe, H. J., Holzman, C., Johnson, E. O., Kennedy, M., Laucht, M., Martin, N. G., Munafò, M. R., Nilsson, K. W., Oldehinkel, A. J., Olsson, C. A., Ormel, J., Otte, C., Patton, G. C., Penninx, B. W. J. H., Ritchie, K., Sarchiapone, M., Scheid, J. M., Serretti, A., Smit, J. H., Stefanis, N. C., Surtees, P. G., Völzke, H., Weinstein, M., Whooley, M., Nurnberger, J. I., Breslau, N. & Bierut, L. J., Jan 1 2018, In : Molecular Psychiatry. 23, 1, p. 133-142 10 p.

    Research output: Contribution to journalArticle

  • 116 Scopus citations