Personal profile
Research interests
My current research focuses on examining the phenotypic (anatomic, physiologic, and clinical) heterogeneity among patients with hypertrophic cardiomyopathy (HCM) and their family members, including genotype-phenotype relationships that may account for this heterogeneity, novel diagnostic methods to diagnose at risk individuals before clinically manifest disease, and on the effect of therapeutic interventions on coronary and myocardial physiology in patients with severe obstructive HCM. Research is also directed at management and outcomes of patients with coronary artery disease (CAD) and acute coronary syndromes.
Clinical interests
Interventional cardiology, coronary angioplasty, atherectomy and stenting, valvuloplasty, peripheral intervention, percutaneous atrial septal defect closure, transcoronary alcohol septal ablation for HCM, cardiac catheterization, hypertrophic cardiomyopathy with obstruction, coronary ultrasonographic and physiologic assessment, cardiac critical care
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Collaborations and top research areas from the last five years
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A Deep Learning Model to Guide Personalized Mechanical Circulatory Support Use in Cardiogenic Shock Patients Undergoing PCI
Amin, A. P., Bach, R. G., Tsang, D. C., Zheng, W. S., Qarajeh, R. A., Brilakis, E. S. & Kulkarni, H., Jan 2026, In: JACC: Advances. 5, 1, 102379.Research output: Contribution to journal › Article › peer-review
Open Access -
Association Between age or Duration of Diagnosis in Obstructive Hypertrophic Cardiomyopathy and Response to Mavacamten Treatment: Exploratory Analysis of the EXPLORER-HCM Trial
WANG, A., LAKDAWALA, N. K., ABRAHAM, T. P., NILLES, E. K., WOJDYLA, D. M., OWENS, A. T., BACH, R. G., SABERI, S. A. R. A., SEHNERT, A. M. Y. & CRESCI, S., Jun 2025, In: Journal of cardiac failure. 31, 6, p. 901-911 11 p.Research output: Contribution to journal › Article › peer-review
5 Link opens in a new tab Scopus citations -
Mavacamten-Associated Temporal Changes in Left Atrial Function in Obstructive HCM: Insights From the VALOR-HCM Trial
VALOR-HCM Investigators, Mar 2025, In: JACC: Cardiovascular Imaging. 18, 3, p. 251-262 12 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Link opens in a new tab Scopus citations -
Proteomic Analysis of Valsartan for Attenuating Disease Cardiomyopathy Evolution(VANISH) in Early Sarcomeric Clinical Trial Hypertrophic
Topriceanu, C. C., Vissing, C. R., Raja, A. A., Day, S. M., Russell, M. W., Zahka, K., Pereira, A. C., Colan, S. D., Murphy, A. M., Canter, C., Bach, R. G., Wheeler, M. T., Rossano, J. W., Owens, A. T., Mestroni, L., Taylor, M. R. G., Moon, J. C., Captur, G., Patel, A. R. & Wilmot, I. & 7 others, , Jun 1 2025, In: Circulation: Heart Failure. 18, 6, p. 581-592 12 p.Research output: Contribution to journal › Article › peer-review
2 Link opens in a new tab Scopus citations -
Response to Mavacamten in Patients With High Baseline Left Ventricular Filling Pressures in the EXPLORER-HCM Trial
Cresci, S., Bach, R. G., Owens, A. T., Lakdawala, N. K., Saberi, S., Hegde, S. M., Nilles, E. K., Wojdyla, D. M., Sehnert, A. J. & Wang, A., Jun 1 2025, In: Circulation: Cardiovascular Imaging. 18, 6, e01782.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations