Rebecca Aft

2013

A prospective longitudinal clinical trial evaluating quality of life after breast-conserving surgery and high-dose-rate interstitial brachytherapy for early-stage breast cancer

Garsa, A. A., Ferraro, D. J., Dewees, T. A., Deshields, T. L., Margenthaler, J. A., Cyr, A. E., Naughton, M., Aft, R., Gillanders, W. E., Eberlein, T., Matesa, M. A., Ochoa, L. L. & Zoberi, I., Dec 1 2013, In: International Journal of Radiation Oncology Biology Physics. 87, 5, p. 1043-1050 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

Assessment of cellular proliferation in tumors by PET using ¹⁸F-ISO-1

Dehdashti, F., Laforest, R., Gao, F., Shoghi, K. I., Aft, R. L., Nussenbaum, B., Kreisel, F. H., Bartlett, N. L., Cashen, A., Wagner-Johnson, N. & MacH, R. H., Mar 1 2013, In: Journal of Nuclear Medicine. 54, 3, p. 350-357 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

72 Scopus citations

Cosmetic analysis following breast-conserving surgery and adjuvant high-dose-rate interstitial brachytherapy for early-stage breast cancer: A prospective clinical study

Garsa, A. A., Ferraro, D. J., Dewees, T., Margenthaler, J. A., Naughton, M., Aft, R., Gillanders, W. E., Eberlein, T., Matesa, M. A. & Zoberi, I., Mar 15 2013, In: International Journal of Radiation Oncology Biology Physics. 85, 4, p. 965-970 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Detection of disseminated tumor cells in the bone marrow of breast cancer patients using multiplex gene expression measurements identifies new therapeutic targets in patients at high risk for the development of metastatic disease

Siddappa, C. M., Watson, M. A., Pillai, S. G., Trinkaus, K., Fleming, T. & Aft, R., Jan 2013, In: Breast Cancer Research and Treatment. 137, 1, p. 45-56 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

Endocrine-Therapy-Resistant ESR1 Variants Revealed by Genomic Characterization of Breast-Cancer-Derived Xenografts

Li, S., Shen, D., Shao, J., Crowder, R., Liu, W., Prat, A., He, X., Liu, S., Hoog, J., Lu, C., Ding, L., Griffith, O. L., Miller, C., Larson, D., Fulton, R. S., Harrison, M., Mooney, T., McMichael, J. F., Luo, J. & Tao, Y. & 35 others, Goncalves, R., Schlosberg, C., Hiken, J. F., Saied, L., Sanchez, C., Giuntoli, T., Bumb, C., Cooper, C., Kitchens, R. T., Lin, A., Phommaly, C., Davies, S. R., Zhang, J., Kavuri, M. S., McEachern, D., Dong, Y. Y., Ma, C., Pluard, T., Naughton, M., Bose, R., Suresh, R., McDowell, R., Michel, L., Aft, R., Gillanders, W., DeSchryver, K., Wilson, R. K., Wang, S., Mills, G. B., Gonzalez-Angulo, A., Edwards, J. R., Maher, C., Perou, C. M., Mardis, E. R. & Ellis, M. J., Sep 26 2013, In: Cell Reports. 4, 6, p. 1116-1130 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

509 Scopus citations

IL-12p70-producing patient DC vaccine elicits Tc1-polarized immunity

Carreno, B. M., Becker-Hapak, M., Huang, A., Chan, M., Alyasiry, A., Lie, W. R., Aft, R. L., Cornelius, L. A., Trinkaus, K. M. & Linette, G. P., Aug 1 2013, In: Journal of Clinical Investigation. 123, 8, p. 3383-3394 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

132 Scopus citations

Patient and tumor characteristics associated with breast cancer recurrence after complete pathological response to neoadjuvant chemotherapy

Ju, N. R., Jeffe, D. B., Keune, J. & Aft, R., Jan 2013, In: Breast Cancer Research and Treatment. 137, 1, p. 195-201 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

The effects of bisphosphonates on the bone marrow niche and circulating and disseminated tumor cells

Aft, R. L., May 2013, In: Current Cancer Therapy Reviews. 9, 2, p. 87-96 10 p.

Research output: Contribution to journal › Article › peer-review

2012

Assessment of progesterone receptors in breast carcinoma by PET with 21- ¹⁸F-fluoro-16α,17α-[(R)-(1′-α- furylmethylidene) dioxy]-19-norpregn-4-ene-3,20-dione

Dehdashti, F., Laforest, R., Gao, F., Aft, R. L., Dence, C. S., Zhou, D., Shoghi, K. I., Siegel, B. A., Katzenellenbogen, J. A. & Welch, M. J., Mar 1 2012, In: Journal of Nuclear Medicine. 53, 3, p. 363-370 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

75 Scopus citations

Careers in academic research

Cai, S. F. & Aft, R. L., Nov 1 2012, Physicians' Pathways to Non-Traditional Careers and Leadership Opportunities. Springer New York, Vol. 9781461405511. p. 167-176 10 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Comparison of accelerated partial breast irradiation via multicatheter interstitial brachytherapy versus whole breast radiation

Ferraro, D. J., Garsa, A. A., DeWees, T. A., Margenthaler, J. A., Naughton, M., Aft, R., Gillanders, W. E., Eberlein, T., Matesa, M. A. & Zoberi, I., Mar 29 2012, In: Radiation Oncology. 7, 1, 53.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Compromised margins following mastectomy for stage I-III invasive breast cancer

Yu, J., Mushawah, F. A., Taylor, M. E., Cyr, A. E., Gillanders, W. E., Aft, R. L., Eberlein, T. J., Gao, F. & Margenthaler, J. A., Sep 2012, In: Journal of Surgical Research. 177, 1, p. 102-108 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Could targeting bone delay cancer progression? Potential mechanisms of action of bisphosphonates

Aft, R., Perez, J. R., Raje, N., Hirsh, V. & Saad, F., May 2012, In: Critical Reviews in Oncology/Hematology. 82, 2, p. 233-248 16 p.

Research output: Contribution to journal › Review article › peer-review

13 Scopus citations

Current perspectives on skeletal health and cancer progression across the disease continuum in breast cancer - The role of bisphosphonates

Aft, R., Aug 23 2012, In: ecancermedicalscience. 6, 1, 265.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Disease recurrence in sentinel node-positive breast cancer patients forgoing axillary lymph node dissection

Cyr, A., Gao, F., Gillanders, W. E., Aft, R. L., Eberlein, T. J. & Margenthaler, J. A., Oct 2012, In: Annals of Surgical Oncology. 19, 10, p. 3185-3191 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Effect of (Neo)adjuvant zoledronic acid on disease-free and overall survival in clinical stage II/III breast cancer

Aft, R. L., Naughton, M., Trinkaus, K. & Weilbaecher, K., Jun 26 2012, In: British Journal of Cancer. 107, 1, p. 7-11 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Erratum: Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models (Journal of Clinical Investigation (2012) 122, 4 (1541-1552) DOI: 10.1172/JCI58765)

Ma, C. X., Cai, S., Li, S., Ryan, C. E., Guo, Z., Schaiff, W. T., Lin, L., Hoog, J., Goiffon, R. J., Prat, A., Aft, R. L., Ellis, M. J. & Piwnica-Worms, H., Jul 2 2012, In: Journal of Clinical Investigation. 122, 7, p. 2702 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

2 Scopus citations

Estimated Effects of Potential Interventions to Prevent Decreases in Self-Rated Health Among Breast Cancer Survivors

Schootman, M., Deshpande, A. D., Pruitt, S., Aft, R. & Jeffe, D. B., Feb 2012, In: Annals of Epidemiology. 22, 2, p. 79-86 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Neoadjuvant chemotherapy is associated with improved survival compared with adjuvant chemotherapy in patients with triple-negative breast cancer only after complete pathologic response

Fisher, C. S., Ma, C. X., Gillanders, W. E., Aft, R. L., Eberlein, T. J., Gao, F. & Margenthaler, J. A., Jan 2012, In: Annals of Surgical Oncology. 19, 1, p. 253-258 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

58 Scopus citations

Positive margin rates following breast-conserving surgery for stage I-III breast cancer: Palpable versus nonpalpable tumors

Atkins, J., Mushawah, F. A., Appleton, C., Cyr, A. E., Gillanders, W. E., Aft, R. L., Eberlein, T. J., Gao, F. & Margenthaler, J. A., Sep 2012, In: Journal of Surgical Research. 177, 1, p. 109-115 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

61 Scopus citations

Protection of bone in premenopausal women with breast cancer: Focus on zoledronic acid

Aft, R., 2012, In: International Journal of Women's Health. 4, 1, p. 569-576 8 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

6 Scopus citations

Quality of life over time in women diagnosed with ductal carcinoma in situ, early-stage invasive breast cancer, and age-matched controls

Jeffe, D. B., Pérez, M., Liu, Y., Collins, K. K., Aft, R. L. & Schootman, M., Jul 2012, In: Breast Cancer Research and Treatment. 134, 1, p. 379-391 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

Relevance of Micrometastases and targeting the bone marrow niche with zoledronic acid in breast cancer

Aft, R., May 2012, In: Current Cancer Therapy Reviews. 8, 2, p. 152-160 9 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models

Ma, C. X., Cai, S., Li, S., Ryan, C. E., Guo, Z., Schaiff, W. T., Lin, L., Hoog, J., Goiffon, R. J., Prat, A., Aft, R. L., Ellis, M. J. & Piwnica-Worms, H., Apr 2 2012, In: Journal of Clinical Investigation. 122, 4, p. 1541-1552 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

181 Scopus citations

2011

Are we overtreating papillomas diagnosed on core needle biopsy?

Cyr, A. E., Novack, D., Trinkaus, K., Margenthaler, J. A., Gillanders, W. E., Eberlein, T. J., Ritter, J. & Aft, R. L., Apr 2011, In: Annals of Surgical Oncology. 18, 4, p. 946-951 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

37 Scopus citations

Bisphosphonates in breast cancer: Antitumor effects

Aft, R., Apr 1 2011, In: Clinical Advances in Hematology and Oncology. 9, 4, p. 292-299 8 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Bisphosphonates in breast cancer: Clinical activity and implications of preclinical data

Aft, R., Mar 2011, In: Clinical Advances in Hematology and Oncology. 9, 3, p. 194-205 12 p.

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Breast cancer in elderly women (≥80 years): Variation in standard of care?

Cyr, A., Gillanders, W. E., Aft, R. L., Eberlein, T. J. & Margenthaler, J. A., Mar 1 2011, In: Journal of surgical oncology. 103, 3, p. 201-206 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

37 Scopus citations

Correlates of fear of cancer recurrence in women with ductal carcinoma in situ and early invasive breast cancer

Liu, Y., Pérez, M., Schootman, M., Aft, R. L., Gillanders, W. E. & Jeffe, D. B., Nov 2011, In: Breast Cancer Research and Treatment. 130, 1, p. 165-173 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

88 Scopus citations

Effects of breast cancer surgery and surgical side effects on body image over time

Collins, K. K., Liu, Y., Schootman, M., Aft, R., Yan, Y., Dean, G., Eilers, M. & Jeffe, D. B., Feb 2011, In: Breast Cancer Research and Treatment. 126, 1, p. 167-176 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

131 Scopus citations

Effects of breast cancer surgery and surgical side effects on body image over time

Collins, K. K., Pérez, M., Schootman, M., Aft, R. & Jeffe, D. B., Feb 2011, In: Breast Cancer Research and Treatment. 126, 1, p. 263-264 2 p.

Research output: Contribution to journal › Letter › peer-review

10 Scopus citations

Temporal and spatial cooperation of Snail1 and Twist1 during epithelial-mesenchymal transition predicts for human breast cancer recurrence

Tran, D. D., Corsa, C. A. S., Biswas, H., Aft, R. L. & Longmore, G. D., Dec 2011, In: Molecular Cancer Research. 9, 12, p. 1644-1657 14 p.

Research output: Contribution to journal › Article › peer-review

140 Scopus citations

2010

Accuracy of perceived risk of recurrence among patients with early-stage breast cancer

Liu, Y., Pérez, M., Aft, R. L., Massman, K., Robinson, E., Myles, S., Schootman, M., Gillanders, W. E. & Jeffe, D. B., Mar 2010, In: Cancer Epidemiology Biomarkers and Prevention. 19, 3, p. 675-680 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

Accuracy of ultrasonography and mammography in predicting pathologic response after neoadjuvant chemotherapy for breast cancer

Keune, J. D., Jeffe, D. B., Schootman, M., Hoffman, A., Gillanders, W. E. & Aft, R. L., Apr 2010, In: American journal of surgery. 199, 4, p. 477-484 8 p.

Research output: Contribution to journal › Article › peer-review

96 Scopus citations

A gene expression signature that predicts the therapeutic response of the basal-like breast cancer to neoadjuvant chemotherapy

Lin, Y., Lin, S., Watson, M., Trinkaus, K. M., Kuo, S., Naughton, M. J., Weilbaecher, K., Fleming, T. P. & Aft, R. L., Oct 2010, In: Breast Cancer Research and Treatment. 123, 3, p. 691-699 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

A longitudinal study of factors associated with perceived risk of recurrence in women with ductal carcinoma in situ and early-stage invasive breast cancer

Liu, Y., Pérez, M., Schootman, M., Aft, R. L., Gillanders, W. E., Ellis, M. J. & Jeffe, D. B., Dec 2010, In: Breast Cancer Research and Treatment. 124, 3, p. 835-844 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

38 Scopus citations

Changes in sexual problems over time in women with and without early-stage breast cancer

Pérez, M., Liu, Y., Schootman, M., Aft, R. L., Schechtman, K. B., Gillanders, W. E. & Jeffe, D. B., Sep 2010, In: Menopause. 17, 5, p. 924-937 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

Correction: Accuracy of perceived risk of recurrence among patients with early-stage breast cancer (Cancer Epidemiol Biomarkers Prev (2010) 19, (675-680) doi: 10.1158/1055-9965.EPI-10-0403)

Liu, Y., Pérez, M., Aft, R. L., Massman, K. L., Robinson, E., Myles, S. L., Schootman, M., Gillanders, W. E., Yan, Y. & Jeffe, D. B., Jun 2010, In: Cancer Epidemiology Biomarkers and Prevention. 19, 6, p. 1661 1 p.

Research output: Contribution to journal › Comment/debate

Effect of zoledronic acid on disseminated tumour cells in women with locally advanced breast cancer: An open label, randomised, phase 2 trial

Aft, R., Naughton, M., Trinkaus, K., Watson, M., Ylagan, L., Chavez-MacGregor, M., Zhai, J., Kuo, S., Shannon, W., Diemer, K., Herrmann, V., Dietz, J., Ali, A., Ellis, M., Weiss, P., Eberlein, T., Ma, C., Fracasso, P. M., Zoberi, I. & Taylor, M. & 4 others, Gillanders, W., Pluard, T., Mortimer, J. & Weilbaecher, K., May 2010, In: The Lancet Oncology. 11, 5, p. 421-428 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

252 Scopus citations

Genome remodelling in a basal-like breast cancer metastasis and xenograft

Ding, L., Ellis, M. J., Li, S., Larson, D. E., Chen, K., Wallis, J. W., Harris, C. C., McLellan, M. D., Fulton, R. S., Fulton, L. L., Abbott, R. M., Hoog, J., Dooling, D. J., Koboldt, D. C., Schmidt, H., Kalicki, J., Zhang, Q., Chen, L., Lin, L. & Wendl, M. C. & 49 others, McMichael, J. F., Magrini, V. J., Cook, L., McGrath, S. D., Vickery, T. L., Appelbaum, E., Deschryver, K., Davies, S., Guintoli, T., Lim, L., Crowder, R., Tao, Y., Snider, J. E., Smith, S. M., Dukes, A. F., Sanderson, G. E., Pohl, C. S., Delehaunty, K. D., Fronick, C. C., Pape, K. A., Reed, J. S., Robinson, J. S., Hodges, J. S., Schierding, W., Dees, N. D., Shen, D., Locke, D. P., Wiechert, M. E., Eldred, J. M., Peck, J. B., Oberkfell, B. J., Lolofie, J. T., Du, F., Hawkins, A. E., Oĝlaughlin, M. D., Bernard, K. E., Cunningham, M., Elliott, G., Mason, M. D., Thompson, D. M., Ivanovich, J. L., Goodfellow, P. J., Perou, C. M., Weinstock, G. M., Aft, R., Watson, M., Ley, T. J., Wilson, R. K. & Mardis, E. R., Apr 15 2010, In: Nature. 464, 7291, p. 999-1005 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1019 Scopus citations

Impact of multiple caregiving roles on elevated depressed mood in early-stage breast cancer patients and same-age controls

Bailey, E. H., Pérez, M., Aft, R. L., Liu, Y., Schootman, M. & Jeffe, D. B., Jun 2010, In: Breast Cancer Research and Treatment. 121, 3, p. 709-718 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Micrometastatic disease and isolated tumor cells as a predictor for additional breast cancer axillary metastatic burden

Cyr, A., Gillanders, W. E., Aft, R. L., Eberlein, T. J., Gao, F. & Margenthaler, J. A., Oct 2010, In: Annals of Surgical Oncology. 17, SUPPL. 3, p. S303-S311

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

National estimates of racial disparities in health status and behavioral risk factors among long-term cancer survivors and non-cancer controls

Schootman, M., Deshpande, A. D., Pruitt, S. L., Aft, R. & Jeffe, D. B., Sep 2010, In: Cancer Causes and Control. 21, 9, p. 1387-1395 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

Temporal trends in area socioeconomic disparities in breast-cancer incidence and mortality, 1988-2005

Schootman, M., Lian, M., Deshpande, A. D., Baker, E. A., Pruitt, S. L., Aft, R. & Jeffe, D. B., Jul 2010, In: Breast Cancer Research and Treatment. 122, 2, p. 533-543 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

Temporal trends in geographic disparities in small-area breast cancer incidence and mortality, 1988 to 2005

Schootman, M., Lian, M., Deshpande, A. D., Baker, E. A., Pruitt, S. L., Aft, R. & Jeffe, D. B., Apr 2010, In: Cancer Epidemiology Biomarkers and Prevention. 19, 4, p. 1122-1131 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

2009

An evaluation of lower-body functional limitations among long-term survivors of 11 different types of cancers

Schootman, M., Aft, R. & Jeffe, D. B., Nov 15 2009, In: Cancer. 115, 22, p. 5329-5338 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Chemosensitizing and cytotoxic effects of 2-deoxy-D-glucose on breast cancer cells.

Zhang, F. & Aft, R. L., 2009, In: Journal of cancer research and therapeutics. 5 Suppl 1, p. S41-43

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Method of breast cancer presentation and depressed mood 1 year after diagnosis in women with locally advanced disease

Roth, E. B., Jeffe, D. B., Margenthaler, J. A. & Aft, R. L., Jun 2009, In: Annals of Surgical Oncology. 16, 6, p. 1637-1641 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Patient and tumor characteristics associated with increased mortality in young women (≤40 years) with breast cancer

Bharat, A., Aft, R. L., Gao, F. & Margenthaler, J. A., 2009, In: Journal of surgical oncology. 100, 3, p. 248-251 4 p.

Research output: Contribution to journal › Article › peer-review

125 Scopus citations

Predictors of complete pathological response after neoadjuvant systemic therapy for breast cancer

Tan, M. C., Al Mushawah, F., Gao, F., Aft, R. L., Gillanders, W. E., Eberlein, T. J. & Margenthaler, J. A., Oct 2009, In: American journal of surgery. 198, 4, p. 520-525 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

67 Scopus citations

Rebecca Aft

Research output

Search results